Skip to menu Skip to content Skip to footer

2010

Conference Publication

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

2010

Journal Article

Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model

Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031

Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model

2009

Journal Article

Influence of perfusate composition on drug disposition in the in-situ perfused rat lung

Liu, X., Wang, J. Y., Khlentzos, A. M., Fontaine, F., Nikolovski, J., Goh, L.- A. and Roberts, M. S. (2009). Influence of perfusate composition on drug disposition in the in-situ perfused rat lung. International Journal of Pharmaceutics, 382 (1-2), 192-197. doi: 10.1016/j.ijpharm.2009.08.028

Influence of perfusate composition on drug disposition in the in-situ perfused rat lung

2009

Book Chapter

Optimizing drug dosing in the ICU

Kruger, P., Liu, X. and Roberts, M. S. (2009). Optimizing drug dosing in the ICU. Optimizing Drug Dosing in the ICU. (pp. 859-869) edited by Vincent, JL. Berlin, Germany: Springer. doi: 10.1007/978-3-540-92276-6

Optimizing drug dosing in the ICU

2008

Journal Article

Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma.

Liu, Xin, Chan, S. Y. and Ho, P. C. (2008). Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma.. Cancer Chemotherapy and Pharmacology, 63 (1), 167-174. doi: 10.1007/s00280-008-0763-1

Comparison of the in vitro and in vivo effects of retinoids either alone or in combination with cisplatin and 5-fluorouracil on tumor development and metastasis of melanoma.

2008

Journal Article

The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement

Li, P., Wang, G-J., Li, J., Liu, X., Khlentzos, A. and Roberts, M. S. (2008). The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement. Current Drug Metabolism, 9 (1), 39-45. doi: 10.2174/138920008783331103

The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement

2007

Journal Article

In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species

Venkadesh, Pilla Reddy, Goh, Evelyn, Zeng, Peizi, New, Lee Sun, Liu, Xin, Pasha, Mohammed Khalid, Sangthongpitag, Kanda, Yeo, Pauline and Kantharaj, Ethirajulu (2007). In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species. Biological and Pharmaceutical Bulletin, 30 (5), 1021-1024. doi: 10.1248/bpb.30.1021

In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species

2007

Journal Article

Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies

Yeo, Pauline, Xin, Liu, Goh, Evelyn, New, Lee Sun, Zeng, Peizi, Wu, Xiaofeng, Venkatesh, P. and Kantharaj, Ethirajulu (2007). Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies. Biomedical Chromatography, 21 (2), 184-189. doi: 10.1002/bmc.734

Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies

2006

Conference Publication

ADME and PK/PD attributes of SB939, a potent orally active HDAC inhibitor

Sangthongpitag, K., Wang, H., Yeo, P., Liu, X., Goh, E., New, L., Zeng, P., Wu, X., Hu, C. and Ethirajulu, K. (2006). ADME and PK/PD attributes of SB939, a potent orally active HDAC inhibitor. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(06)70172-0

ADME and PK/PD attributes of SB939, a potent orally active HDAC inhibitor

2005

Journal Article

Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis

Yap, K. L., Liu, X., Thenmozhiyal, J. C. and Ho, P. C. (2005). Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis. European Journal of Pharmaceutical Sciences, 25 (1), 49-56. doi: 10.1016/j.ejps.2005.01.021

Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis

2004

Journal Article

Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats

Liu, X., Lin, H. S., Chan, S. Y. and Ho, P. C. (2004). Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats. Journal of Pharmaceutical Sciences, 93 (4), 805-815. doi: 10.1002/jps.10578

Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats

2003

Journal Article

Inclusion of acitretin into cyclodextrins: Phase solubility, photostability, and physicochemical characterization

Liu, X., Lin, H. S., Thenmozhiyal, J. C., Chan, S. Y. and Ho, P. C. (2003). Inclusion of acitretin into cyclodextrins: Phase solubility, photostability, and physicochemical characterization. Journal of Pharmaceutical Sciences, 92 (12), 2449-2457. doi: 10.1002/jps.10495

Inclusion of acitretin into cyclodextrins: Phase solubility, photostability, and physicochemical characterization