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2017

Conference Publication

Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study)

Coles, A. J., Boyko, A. N., De Seze, J., Hartung, H-P., Havrdova, E., Inshasi, J. S., McCombe, P., Montalban, X., Pozzilli, C., Selmaj, K. W., Vermersch, P., Margolin, D. H., Daizadeh, N., Rodriguez, C. E. and Van Wijmeersch, B. (2017). Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study). 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study)

2017

Conference Publication

The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis

Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Prat, A., Girard, M., Hupperts, R., Van Pesch, V., Ferraro, D., Alroughani, R., Bergamaschi, R., Pucci, E., Iuliano, G., Lechner-Scott, J., Spelman, T., Jokubaitis, V., Ramo-Tello, C., Spitaleri, D., Granella, F., Solaro, C., Ampapa, R., Deri, N., McCombe, P., Petersen, T., Van Wijmeersch, B., Prevost, J., Sanchez-Menoyo, J. L. ... Robsertson, N. (2017). The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731283

The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis

2016

Conference Publication

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program

Oh, Jiwon, Achiron, Anat, Chambers, Christina, Fox, Edward, McCombe, Pamela, Otero, Susana, Margolin, David, Kasten, Linda and Compston, D. Alastair (2016). Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program. AAN 68th Annual Meeting, Vancouver, Canada, 15 - 21 April 2016. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.86.16_supplement.s24.008

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program

2016

Conference Publication

Prospectively tracking disease course and treatment changes in Neuromyelitis Optica using NMOBase, a global online registry

Kister, Ilya, Bacon, Tamar, Shaygannejad, Vahid, Hor, Jyh Yung, Alroughani, Raed, Haas, Shannon, Terzi, Murat, Boz, Cavit, Olascoaga, Javier, McCombe, Pamela, Fragoso, Yara, Lugaresi, Alessandra, Sola, Patrizia, Vucic, Steve, Pucci, Eugenio, Al-Harbi, Talal, Sajedi, Seyed Aidin, Rojas, Juan Ignacio, Patrucco, Liliana, Cristiano, Edgardo, Suarez, Jose Alberto, Tsolaki, Magdalini, Taylor, Bruce, Iuliano, Gerardo, Devranis, Paschalis, Marriott, Mark and Butzkueven, Helmut (2016). Prospectively tracking disease course and treatment changes in Neuromyelitis Optica using NMOBase, a global online registry. AAN 68th Annual Meeting, Vancouver, Canada, 15 - 21 April 2016. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.86.16_supplement.p5.307

Prospectively tracking disease course and treatment changes in Neuromyelitis Optica using NMOBase, a global online registry

2016

Conference Publication

Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.

McCombe, P., Achiron, A., Chambers, C., Fox, E. J., Otero, S., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2016). Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.. 8th Congress of the Pan-Asian-Committee-for-Research-and-Treatment-of-Multiple-Sclerosis (PACTRIMS), Seoul South Korea, Nov 19-21, 2015. LONDON: SAGE PUBLICATIONS LTD.

Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.

2016

Conference Publication

Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study

McCombe, P. A., Hartung, H-P, Havrdova, E., Selmaj, K. W., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2016). Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study. 8th Congress of the Pan-Asian-Committee-for-Research-and-Treatment-of-Multiple-Sclerosis (PACTRIMS), Seoul South Korea, Nov 19-21, 2015. LONDON: SAGE PUBLICATIONS LTD.

Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study

2016

Conference Publication

Individual response to disease modifying therapies: a global observational cohort study

Kalincik, T., Sobisek, L., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Girard, M., Prat, A., Duquette, P., Grammond, P., Sola, P., Hupperts, R., Grand'Maison, F., Pucci, E., Boz, C., Alroughani, R., Van Pesch, V., Lechner-Scott, J., Terzi, M., Bergamaschi, R., Iuliano, G., Granella, F., Spitaleri, D., Shaygannejad, V., Oreja-Guevara, C., Slee, M. ... Butzkueven, H. (2016). Individual response to disease modifying therapies: a global observational cohort study. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Individual response to disease modifying therapies: a global observational cohort study

2016

Conference Publication

Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms

Rog, David, Chambers, Christina, McCombe, Pamela, Otero, Susana, Hellwig, Kerstin, Margolin, David, Thangavelu, Karthinathan and Oh, Jiwon (2016). Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms. Annual Meeting of the Association-of-British-Neurologists (ABN), Brighton, England, May 17-19, 2016. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2016-315106.155

Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms

2016

Conference Publication

Pregnancy protects against long-term disability accrual in relapsing-remitting MS

Jokubaitis, V. G., Kalincik, T., Lorscheider, J., Spelman, T., Horakova, D., Duquette, P., Girard, M., Prat, A., Izquierdo, G., Grammond, P., Pucci, E., Grand'Maison, F., Granella, F., Sola, P., Bergamaschi, R., Iuliano, G., Spitaleri, D., Hodgkinson, S., Olascoaga, J., Verheul, F., McCombe, P., Rozsa, C., Lechner-Scott, J., Terzi, M., Hughes, S., Saladino, M. -L., Lugaresi, A., Trojano, M. and Butzkueven, H. (2016). Pregnancy protects against long-term disability accrual in relapsing-remitting MS. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Pregnancy protects against long-term disability accrual in relapsing-remitting MS

2016

Conference Publication

Australian cladribine experience

Kalincik, T., Lizak, N., Jokubaitis, V., Butler, E., Lechner-Scott, J., Slee, M., McCombe, P., Shaw, C., Skibina, O., Vucic, S., Shuey, N., Barnett, M., Parratt, J., Butzkueven, H. and Hodgkinson, S. (2016). Australian cladribine experience. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Australian cladribine experience

2016

Conference Publication

Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).

Coles, A. J., Boyko, A. N., Cohen, J. A., De Seze, J., Fox, E. J., Havrdova, E., Hartung, H. -P., Inshasi, J. S., McCombe, P., Selmaj, K. W., Vermersch, P., Van Wijmeersch, B., Margolin, D. H., Thangavelu, K., Rodriguez, C. E. and Montalban, X. (2016). Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).

2016

Conference Publication

Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a

Kalincik, T., Brown, J. W., Robertson, N., Willis, M., Scolding, N., Pearson, O., Ziemssen, T., Hutchinson, M., McGuigan, C., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Alroughani, R., Pucci, E., Sola, P., Hupperts, R., Lechner-Scott, J., Fernandez Bolanos, R., Terzi, M., Van Pesch, V., Rozsa, C. ... Coles, A. (2016). Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a

2016

Conference Publication

Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up)

Oreja-Guevara, C., Alroughani, R., Brassat, D., Boyko, A. N., McCombe, P., Steingo, B., Van Wijmeersch, B., Margolin, D. H., Thangavelu, K., Rodriguez, C. E. and Vermersch, P. (2016). Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up). 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up)

2015

Conference Publication

Defining secondary progressive multiple sclerosis

Lorscheider, Johannes, Buzzard, Katherine, Jokubaitis, Vilija, Spelman, Tim, Lechner-Scott, Jeannette, McCombe, Pam, Vucic, Steve, Barnett, Michael, Butzkueven, Helmut and Kalincik, Tomas (2015). Defining secondary progressive multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne Australia, Oct 29-30, 2015. LONDON: SAGE PUBLICATIONS LTD.

Defining secondary progressive multiple sclerosis

2015

Conference Publication

Pregnancy outcomes in patients with active RRMS who received alemtuzumab in the clinical development program

Achiron, A., Chambers, C., Fox, E. J., Mc Combe, P., Otero, S., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2015). Pregnancy outcomes in patients with active RRMS who received alemtuzumab in the clinical development program. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

Pregnancy outcomes in patients with active RRMS who received alemtuzumab in the clinical development program

2015

Conference Publication

Defining secondary progressive multiple sclerosis

Lorscheider, J., Buzzard, K., Jokubaitis, V., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Girard, M., Duquette, P., Prat, A., Lugaresi, A., Grand'Maison, F., Grammond, P., Hupperts, R., Alroughani, R., Sola, P., Boz, C., Terzi, M., Pucci, E., Lechner-Scott, J., Bergamaschi, R., Oreja-Guevara, C., Iuliano, G., Van Pesch, V., Bolanos, R. Fernandez, Granella, F., Rio, M. E., Ramo, C. ... Kalincik, T. (2015). Defining secondary progressive multiple sclerosis. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

Defining secondary progressive multiple sclerosis

2015

Conference Publication

Effect of relapse phenotype on the accumulation of disability in relapsing-remitting multiple sclerosis

Stewart, T., Jokubaitis, V., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Girard, M., Duquette, P., Prat, A., Lugaresi, A., Grammond, P., Grand'Maison, F., Sola, P., Hupperts, R., Petersen, T., Pucci, E., Bergamaschi, R., Boz, C., Oreja-Guevara, C., Lechner-Scott, J., Alroughani, R., Ramo, C., Van Pesch, V., Fernandez-Bolanos, R., Iuliano, G., Rio, M. E., Granella, F., Slee, M. ... Kalincik, T. (2015). Effect of relapse phenotype on the accumulation of disability in relapsing-remitting multiple sclerosis. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

Effect of relapse phenotype on the accumulation of disability in relapsing-remitting multiple sclerosis

2015

Conference Publication

10-year progression predictors after first treatment initiation in a relapsing-remitting MS cohort

Jokubaitis, V. G., Spelman, T., Kalincik, T., Travaglini, D., Paolicelli, D., Duquette, P., Girard, M., Prat, A., Havrdova, E., Horakova, D., Izquierdo, G., Grammond, P., Pucci, E., Grand'Maison, F., Bergamaschi, R., Granella, F., Van Pesch, V., Hupperts, R., Iuliano, G., Spitaleri, D., Sola, P., Boz, C., Fernandez-Bolanos, R., Petersen, T., Verheul, F., Olascoaga, J., McCombe, P., Rozsa, C., Lechner-Scott, J. ... Trojano, M. (2015). 10-year progression predictors after first treatment initiation in a relapsing-remitting MS cohort. 31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona Spain, Oct 07-10, 2015. LONDON: SAGE PUBLICATIONS LTD.

10-year progression predictors after first treatment initiation in a relapsing-remitting MS cohort

2015

Conference Publication

Pregnancy outcomes in the alemtuzumab MS clinical development program

McCombe, P., Achiron, A., Brinar, V., Margolin, D. H., Palmer, J., Oyuela, P. and Compston, D. A. S. (2015). Pregnancy outcomes in the alemtuzumab MS clinical development program. Pactrims Invited Lecture, Unknown, Unknown. London, United Kingdom: Sage Publications. doi: 10.1177/1352458514563659

Pregnancy outcomes in the alemtuzumab MS clinical development program

2015

Conference Publication

First-line injectable therapy and pregnancy protect against long-term disability accrual in patients with relapse-onset multiple sclerosis

Jokubaitis, Vilija, Spelman, Tim, Kalincik, Tomask, Lorscheider, Johannes, McCombe, Pamela, Lechner-Scott, Jeannette, Hodgkinson, Suzanne and Butzkueven, Helmut (2015). First-line injectable therapy and pregnancy protect against long-term disability accrual in patients with relapse-onset multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne, Australia, Oct 29-30, 2015. London, United Kingdom: Sage Publications. doi: 10.1177/1352458515616527

First-line injectable therapy and pregnancy protect against long-term disability accrual in patients with relapse-onset multiple sclerosis