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2020

Journal Article

Modern clinician-initiated clinical trials to determine optimal therapy for multi-drug resistant Gram-negative infections

Stewart, Adam G., Harris, Patrick N. A., Chatfield, Mark, Evans, Scott R., van Duin, David and Paterson, David L. (2020). Modern clinician-initiated clinical trials to determine optimal therapy for multi-drug resistant Gram-negative infections. Clinical Infectious Diseases, 71 (2), 433-439. doi: 10.1093/cid/ciz1132

Modern clinician-initiated clinical trials to determine optimal therapy for multi-drug resistant Gram-negative infections

2020

Journal Article

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model

Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20

Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model

2020

Journal Article

Antimicrobial resistance in ESKAPE pathogens

De Oliveira, David M. P., Forde, Brian M., Kidd, Timothy J., Harris, Patrick N. A., Schembri, Mark A., Beatson, Scott A., Paterson, David L. and Walker, Mark J. (2020). Antimicrobial resistance in ESKAPE pathogens. Clinical Microbiology Reviews, 33 (3) e00181-19, e00181-19. doi: 10.1128/cmr.00181-19

Antimicrobial resistance in ESKAPE pathogens

2020

Journal Article

Oral cephalosporin and β-lactamase inhibitor combinations for ESBL-producing Enterobacteriaceae urinary tract infections

Stewart, Adam G., Harris, Patrick N. A., Henderson, Andrew, Schembri, Mark A. and Paterson, David L. (2020). Oral cephalosporin and β-lactamase inhibitor combinations for ESBL-producing Enterobacteriaceae urinary tract infections. Journal of Antimicrobial Chemotherapy, 75 (9), 2384-2393. doi: 10.1093/jac/dkaa183

Oral cephalosporin and β-lactamase inhibitor combinations for ESBL-producing Enterobacteriaceae urinary tract infections

2020

Journal Article

Genomic investigation reveals contaminated detergent as the source of an Extended-Spectrum-β-Lactamase-producing Klebsiella michiganensis outbreak in a neonatal unit

Chapman, Paul, Forde, Brian M., Roberts, Leah W., Bergh, Haakon, Vesey, Debra, Jennison, Amy V., Moss, Susan, Paterson, David L., Beatson, Scott A. and Harris, Patrick N. A. (2020). Genomic investigation reveals contaminated detergent as the source of an Extended-Spectrum-β-Lactamase-producing Klebsiella michiganensis outbreak in a neonatal unit. Journal of Clinical Microbiology, 58 (5) e01980. doi: 10.1128/jcm.01980-19

Genomic investigation reveals contaminated detergent as the source of an Extended-Spectrum-β-Lactamase-producing Klebsiella michiganensis outbreak in a neonatal unit

2020

Journal Article

Beyond the Core Genome: Tracking Plasmids in Outbreaks of Multidrug-resistant Bacteria

Harris, Patrick N. A. and Wailan, Alexander M. (2020). Beyond the Core Genome: Tracking Plasmids in Outbreaks of Multidrug-resistant Bacteria. Clinical Infectious Diseases, 72 (3), 421-422. doi: 10.1093/cid/ciaa052

Beyond the Core Genome: Tracking Plasmids in Outbreaks of Multidrug-resistant Bacteria

2020

Other Outputs

Comparative genomics and antimicrobial resistance profiling of Elizabethkingia isolates reveals nosocomial transmission and in vitro susceptibility to fluoroquinolones, tetracyclines and trimethoprim-sulfamethoxazole

Burnard, Delaney, Gore, Letitia, Henderson, Andrew, Ranasinghe, Ama, Bergh, Haakon, Cottrell, Kyra, Sarovich, Derek S., Price, Erin P., Paterson, David L. and Harris, Patrick N. A. (2020). Comparative genomics and antimicrobial resistance profiling of Elizabethkingia isolates reveals nosocomial transmission and in vitro susceptibility to fluoroquinolones, tetracyclines and trimethoprim-sulfamethoxazole. doi: 10.1101/2020.03.12.20032722

Comparative genomics and antimicrobial resistance profiling of Elizabethkingia isolates reveals nosocomial transmission and in vitro susceptibility to fluoroquinolones, tetracyclines and trimethoprim-sulfamethoxazole

2020

Conference Publication

Pharmacodynamic evaluation of intermittent versus prolonged infusion dosing regimens of piperacillin/tazobactam in a hollow-fiber infection model against two susceptible Klebsiella pneumoniae clinical isolates

Sumi, Chandra Datta, B.Sime, Fekade, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Harris, Patrick N.A. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus prolonged infusion dosing regimens of piperacillin/tazobactam in a hollow-fiber infection model against two susceptible Klebsiella pneumoniae clinical isolates. Federation of Infection Societies Conference 2019, Edinburgh, United Kingdom, 11-14 November 2019. London, United Kingdom: The Microbiology Society. doi: 10.1099/acmi.fis2019.po0103

Pharmacodynamic evaluation of intermittent versus prolonged infusion dosing regimens of piperacillin/tazobactam in a hollow-fiber infection model against two susceptible Klebsiella pneumoniae clinical isolates

2020

Journal Article

Current evidence for therapy of ceftriaxone-resistant Gram-negative bacteremia

Paterson, David L., Henderson, Andrew and Harris, Patrick N. A. (2020). Current evidence for therapy of ceftriaxone-resistant Gram-negative bacteremia. Current Opinion in Infectious Diseases, 33 (1), 78-85. doi: 10.1097/QCO.0000000000000623

Current evidence for therapy of ceftriaxone-resistant Gram-negative bacteremia

2020

Journal Article

Measuring patient-centred long-term outcome following a bloodstream infection: a pilot study

McNamara, J. F., Harris, P. N. A., Chatfield, M. D., Lorenc, P. and Paterson, D. L. (2020). Measuring patient-centred long-term outcome following a bloodstream infection: a pilot study. Clinical Microbiology and Infection, 26 (2), 257.e1-257.e4. doi: 10.1016/j.cmi.2019.10.011

Measuring patient-centred long-term outcome following a bloodstream infection: a pilot study

2020

Journal Article

Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei

Roberts, Leah W., Harris, Patrick N. A., Forde, Brian M., Ben Zakour, Nouri L., Catchpoole, Elizabeth, Stanton-Cook, Mitchell, Phan, Minh-Duy, Sidjabat, Hanna E., Bergh, Haakon, Heney, Claire, Gawthorne, Jayde A., Lipman, Jeffrey, Allworth, Anthony, Chan, Kok-Gan, Chong, Teik Min, Yin, Wai-Fong, Schembri, Mark A., Paterson, David L. and Beatson, Scott A. (2020). Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei. Nature Communications, 11 (1) 466, 466. doi: 10.1038/s41467-019-14139-5

Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei

2020

Journal Article

A hybrid simulation model approach to examine bacterial genome sequencing during a hospital outbreak

Elliott, Thomas M., Lee, Xing J., Foeglein, Anna, Harris, Patrick N. and Gordon, Louisa G. (2020). A hybrid simulation model approach to examine bacterial genome sequencing during a hospital outbreak. BMC Infectious Diseases, 20 (1) 72, 72. doi: 10.1186/s12879-019-4743-3

A hybrid simulation model approach to examine bacterial genome sequencing during a hospital outbreak

2020

Journal Article

Bacterial profile, multi-drug resistance and seasonality following lower limb orthopaedic surgery in tropical and subtropical Australian hospitals: an epidemiological cohort study

Vickers, Mark L., Ballard, Emma L., Harris, Patrick N. A., Knibbs, Luke D., Jaiprakash, Anjali, Dulhunty, Joel M., Crawford, Ross W. and Parkinson, Benjamin (2020). Bacterial profile, multi-drug resistance and seasonality following lower limb orthopaedic surgery in tropical and subtropical Australian hospitals: an epidemiological cohort study. International Journal of Environmental Research and Public Health, 17 (2) 657, 1-15. doi: 10.3390/ijerph17020657

Bacterial profile, multi-drug resistance and seasonality following lower limb orthopaedic surgery in tropical and subtropical Australian hospitals: an epidemiological cohort study

2020

Journal Article

Erratum to ‘When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit’ [Clin Microbiol Infect 26 (1) (January 2020) 35–40](S1198743X19303969)(10.1016/j.cmi.2019.07.007)

Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N.A. and Lipman, J. (2020). Erratum to ‘When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit’ [Clin Microbiol Infect 26 (1) (January 2020) 35–40](S1198743X19303969)(10.1016/j.cmi.2019.07.007). Clinical Microbiology and Infection, 26 (6), 801-801. doi: 10.1016/j.cmi.2020.01.016

Erratum to ‘When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit’ [Clin Microbiol Infect 26 (1) (January 2020) 35–40](S1198743X19303969)(10.1016/j.cmi.2019.07.007)

2020

Journal Article

Clinical and Economic Outcomes of Genome Sequencing Availability on Containing a Hospital Outbreak of Resistant Escherichia coli in Australia

Lee, Xing J., Elliott, Thomas M., Harris, Patrick N. A., Douglas, Joel, Henderson, Belinda, Watson, Catherine, Paterson, David L., Schofield, Deborah S., Graves, Nicholas and Gordon, Louisa G. (2020). Clinical and Economic Outcomes of Genome Sequencing Availability on Containing a Hospital Outbreak of Resistant Escherichia coli in Australia. Value in Health, 23 (8), 994-1002. doi: 10.1016/j.jval.2020.03.006

Clinical and Economic Outcomes of Genome Sequencing Availability on Containing a Hospital Outbreak of Resistant Escherichia coli in Australia

2020

Journal Article

Evaluating the economic effects of genomic sequencing of pathogens to prioritise hospital patients competing for isolation beds

Elliott, Thomas M., Hare, Nicole, Hajkowicz, Krispin, Hurst, Trish, Doidge, Michelle, Harris, Patrick N. and Gordon, Louisa G. (2020). Evaluating the economic effects of genomic sequencing of pathogens to prioritise hospital patients competing for isolation beds. Australian Health Review, 45 (1), 59-65. doi: 10.1071/AH20071

Evaluating the economic effects of genomic sequencing of pathogens to prioritise hospital patients competing for isolation beds

2020

Conference Publication

Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings

Ayfan, A., Ertl, N., Whiley, D., Paterson, D., Heney, C., Harris, P., Macdonald, J., Irwin, A. and Zowawi, H. (2020). Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings. GCCMID 2019, Dubai, United Arab Emirates, 6-9 November 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2020.01.059

Rapid and sensitive molecular detection of antimicrobial resistance (AMR); towards point-of-care testing in low resource settings

2020

Conference Publication

Molecular epidemiology and hospital spread of ceftriaxone non-susceptible enterobacterales in the Sunshine Coast region, Australia

Stewart, Adam, Sarovich, Derek, Price, Erin, Burnard, Delaney, Harris, Patrick, Choong, Keat and Subedi, Shradha (2020). Molecular epidemiology and hospital spread of ceftriaxone non-susceptible enterobacterales in the Sunshine Coast region, Australia. RACP Congress 2020: Balancing medical science with humanity, Online, May 2020. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/imj.4_14846

Molecular epidemiology and hospital spread of ceftriaxone non-susceptible enterobacterales in the Sunshine Coast region, Australia

2020

Journal Article

When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit

Denny, K. J., De Waele, J., Laupland, K. B., Harris, P. N. A. and Lipman, J. (2020). When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit. Clinical Microbiology and Infection, 26 (1), 35-40. doi: 10.1016/j.cmi.2019.07.007

When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit

2019

Journal Article

Genomic analysis of carbapenemase-producing Enterobacteriaceae in Queensland reveals widespread transmission of blaIMP-4 on an IncHI2 plasmid

Roberts, Leah W., Catchpoole, Elizabeth, Jennison, Amy V., Bergh, Haakon, Hume, Anna, Heney, Claire, George, Narelle, Paterson, David L., Schembri, Mark A., Beatson, Scott A. and Harris, Patrick N. A. (2019). Genomic analysis of carbapenemase-producing Enterobacteriaceae in Queensland reveals widespread transmission of blaIMP-4 on an IncHI2 plasmid. Microbial Genomics, 6 (1) 000321. doi: 10.1099/mgen.0.000321

Genomic analysis of carbapenemase-producing Enterobacteriaceae in Queensland reveals widespread transmission of blaIMP-4 on an IncHI2 plasmid