|
2017 Journal Article Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohortGarton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302 |
|
2017 Journal Article 10 years of GWAS discovery: biology, function, and translationVisscher, Peter M., Wray, Naomi R., Zhang, Qian, Sklar, Pamela, McCarthy, Mark I., Brown, Matthew A. and Yang, Jian (2017). 10 years of GWAS discovery: biology, function, and translation. American Journal of Human Genetics, 101 (1), 5-22. doi: 10.1016/j.ajhg.2017.06.005 |
|
2017 Journal Article Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Alda, M., Alliey-Rodriguez, N., Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S., Bethell, A., Biernacka, J. M. ... Rietschel, M. (2017). Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.. Translational psychiatry, 7 (6), e1155-e1155. doi: 10.1038/tp.2017.115 |
|
2017 Journal Article Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneityMcCombe, P. A., Wray, N. R. and Henderson, R. D. (2017). Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity. Expert Review of Neurotherapeutics, 17 (6), 561-577. doi: 10.1080/14737175.2017.1273772 |
|
2017 Journal Article Maternal depression and family adversity: linked pathways to offspring depression?Najman, Jake M., Plotnikova, M., Williams, G. M., Alati, R., Mamun, A. A., Scott, J., Clavarino, A. M. and Wray, N. (2017). Maternal depression and family adversity: linked pathways to offspring depression?. Journal of Psychiatric Research, 88, 97-104. doi: 10.1016/j.jpsychires.2017.01.006 |
|
2017 Journal Article Genetic signatures of high-altitude adaptation in TibetansYang, Jian, Jin, Zi-Bing, Chen, Jie, Huang, Xiu-Feng, Li, Xiao-Man, Liang, Yuan-Bo, Mao, Jian-Yang, Chen, Xin, Zheng, Zhili, Bakshi, Andrew, Zheng, Dong-Dong, Zheng, Mei-Qin, Wray, Naomi R., Visscher, Peter M., Lu, Fan and Qu, Jia (2017). Genetic signatures of high-altitude adaptation in Tibetans. Proceedings of the National Academy of Sciences, 114 (16), 4189-4194. doi: 10.1073/pnas.1617042114 |
|
2017 Journal Article Genetic effects influencing risk for major depressive disorder in China and EuropeBigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A, Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschon, H. N., Byrne, E. M., Cichon, S., Clarke, T-K, Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F., Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P. ... Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry, 7 (3) e1074, e1074-e1074. doi: 10.1038/tp.2016.292 |
|
2017 Journal Article Genetic correlation between amyotrophic lateral sclerosis and schizophreniaMcLaughlin, Russell L., Schijven, Dick, Van Rheenen, Wouter, Van Eijk, Kriste R., O'Brien, Margaret, Kahn, Rene S., Ophoff, Roel A., Goris, An, Bradley, Daniel G., Al-Chalabi, Ammar, Van Den Berg, Leonard H., Luykx, Jurjen J., Hardiman, Orla, Veldink, Jan H., Project MinE GWAS Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M. and Mowry, Bryan J. (2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications, 8 (1) 14774, 14774. doi: 10.1038/ncomms14774 |
|
2017 Journal Article Using information of relatives in genomic prediction to apply effective stratified medicineLee, S. Hong, Weerasinghe, W. M. Shalanee P., Wray, Naomi R., Goddard, Michael E. and Van Der Werf, Julius H. J. (2017). Using information of relatives in genomic prediction to apply effective stratified medicine. Scientific Reports, 7 (1) 42091, 42091. doi: 10.1038/srep42091 |
|
2017 Journal Article Trajectories of maternal depression: a 27-year population-based prospective studyNajman, J. M., Plotnikova, M., Williams, G. M., Alati, R., Mamun, A. A., Scott, J., Wray, N. and Clavarino, A. M. (2017). Trajectories of maternal depression: a 27-year population-based prospective study. Epidemiology and Psychiatric Sciences, 26 (1), 79-88. doi: 10.1017/S2045796015001109 |
|
2017 Journal Article Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutationsGratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2017). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Obstetrical and Gynecological Survey, 72 (2), 96-96. doi: 10.1097/01.OGX.0000512485.13448.C7 |
|
2017 Journal Article Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approachMendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan, North, Kari, Sundstrom, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F., Harris, Sarah E., Gibson, Jude, Redmond, Paul, Corley, Janie ... Deary, Ian J. (2017). Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach. PLoS Medicine, 14 (1) e1002215, e1002215. doi: 10.1371/journal.pmed.1002215 |
|
2017 Journal Article Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjectsMarshall, Christian R., Howrigan, Daniel P., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wu, Wenting, Greer, Douglas S., Antaki, Danny, Shetty, Aniket, Holmans, Peter A., Pinto, Dalila, Gujral, Madhusudan, Brandler, William M., Malhotra, Dheeraj, Wang, Zhouzhi, Fuentes Fajarado, Karin V., Maile, Michelle S., Ripke, Stephan, Agartz, Ingrid, Albus, Margot, Alexander, Madeline, Amin, Farooq, Atkins, Joshua, Bacanu, Silviu A., Belliveau, Richard A., Jr., Bergen, Sarah E., Bertalan, Marcelo, Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W. ... Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 49 (1), 27-35. doi: 10.1038/ng.3725 |
|
2016 Journal Article Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorderZeng, Yanni, Navarro, Pau, Shirali, Masoud, Howard, David M., Adams, Mark J., Hall, Lynsey S., Clarke, Toni-Kim, Thomson, Pippa A., Smith, Blair H., Murray, Alison, Padmanabhan, Sandosh, Hayward, Caroline, Boutin, Thibaud, MacIntyre, Donald J., Lewis, Cathryn M., Wray, Naomi R., Mehta, Divya, Penninx, Brenda W. J. H., Milaneschi, Yuri, Baune, Bernhard T., Air, Tracy, Hottenga, Jouke-Jan, Mbarek, Hamdi, Castelao, Enrique, Pistis, Giorgio, Schulze, Thomas G., Streit, Fabian, Forstner, Andreas J., Byrne, Enda M. ... McIntosh, Andrew M. (2016). Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder. Biological Psychiatry, 82 (5), 312-321. doi: 10.1016/j.biopsych.2016.12.012 |
|
2016 Journal Article A DNA methylation biomarker of alcohol consumptionLiu, C., Marioni, R. E., Hedman, K., Pfeiffer, L., Tsai, P. -C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C., Mendelson, M. M., Joehanes, R., Liang, L., Love, S. -A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H. ... Levy, D. (2016). A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry, 23 (2), 422-433. doi: 10.1038/mp.2016.192 |
|
2016 Journal Article Exploring boundaries for the genetic consequences of assortative mating for psychiatric traitsPeyrot, Wouter J., Robinson, Matthew R., Penninx, Brenda W. J. H. and Wray, Naomi R. (2016). Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits. JAMA Psychiatry, 73 (11), 1189-1195. doi: 10.1001/jamapsychiatry.2016.2566 |
|
2016 Journal Article No reliable association between runs of homozygosity and schizophrenia in a well-powered replication studyJohnson, Emma C., Bjelland, Douglas W., Howrigan, Daniel P., Abdellaoui, Abdel, Breen, Gerome, Borglum, Anders, Cichon, Sven, Degenhardt, Franziska, Forstner, Andreas J., Frank, Josef, Genovese, Giulio, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffman, Per, Maier, Wolfgang, Mattheisen, Manuel, Morris, Derek, Mowry, Bryan, Muller-Mhysok, Betram, Neale, Benjamin, Nenadic, Igor, Nothen, Markus M., O'Dushlaine, Colm, Rietschel, Marcella, Ruderfer, Douglas M., Rujescu, Dan, Schulze, Thomas G., Simonson, Matthew A., Stahl, Eli ... Keller, Matthew C. (2016). No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study. PLoS Genetics, 12 (10) e1006343, e1006343. doi: 10.1371/journal.pgen.1006343 |
|
2016 Journal Article Epigenetic signatures of cigarette smokingJoehanes, Roby, Just, Allan C., Marioni, Riccardo E., Pilling, Luke C., Reynolds, Lindsay M., Mandaviya, Pooja R., Guan, Weihua, Xu, Tao, Elks, Cathy E., Aslibekyan, Stella, Moreno-Macias, Hortensia, Smith, Jennifer A., Brody, Jennifer A., Dhingra, Radhika, Yousefi, Paul, Pankow, James S., Kunze, Sonja, Shah, Sonia H., McRae, Allan F., Lohman, Kurt, Sha, Jin, Absher, Devin M., Ferrucci, Luigi, Zhao, Wei, Demerath, Ellen W., Bressler, Jan, Grove, Megan L., Huan, Tianxiao, Liu, Chunyu ... London, Stephanie J. (2016). Epigenetic signatures of cigarette smoking. Circulation: Cardiovascular Genetics, 9 (5), 436-447. doi: 10.1161/CIRCGENETICS.116.001506 |
|
2016 Journal Article Meta-analysis of genome-wide association studies of anxiety disordersOtowa, T., Hek, K., Lee, M., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T., Aggen, S. H., Adkins, D., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., Der Auwera, S. V., Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J. -J., Direk, N., Hofman, A., Uitterlinden, A., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F. ... Hettema, J. M. (2016). Meta-analysis of genome-wide association studies of anxiety disorders. Molecular Psychiatry, 21 (10), 1391-1399. doi: 10.1038/mp.2015.197 |
|
2016 Journal Article Concepts and misconceptions about the polygenic additive model applied to diseaseVisscher, Peter M. and Wray, Naomi R. (2016). Concepts and misconceptions about the polygenic additive model applied to disease. Human Heredity, 80 (4), 165-170. doi: 10.1159/000446931 |
