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2009

Journal Article

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Psychiatric GWAS Consortium Coordinating Committee, Martin, N., Wray, N., Mowry, B. and Holliday, E. (2009). Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders. American Journal of Psychiatry, 166 (5), 540-556. doi: 10.1176/appi.ajp.2008.08091354

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

2009

Journal Article

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

Sullivan, P. F., de Geus, E. J. C., Willemsen, G., James, M. R., Smit, J. H., Zandbelt, T., Martin, N. G., Wray, N. R., Boomsma, D. I. and Penninx, B. W. J. H. (2009). Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Molecular Psychiatry, 14 (4), 359-375. doi: 10.1038/mp.2008.125

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

2009

Journal Article

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

Evans, David M., Visscher, Peter M. and Wray, Naomi R. (2009). Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk. Human Molecular Genetics, 18 (18), 3525-3531. doi: 10.1093/hmg/ddp295

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

2009

Journal Article

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

International Schizophrenia Consortium and Wray, Naomi (2009). Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460 (7256), 748-752. doi: 10.1038/nature08185

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

2008

Journal Article

Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression

Middeldorp, CM, Sullivan, PF, Wray, NR, Hottenga, JJ, de Geus, EJC, van den Berg, M, Montgomery, GW, Coventry, WL, Statham, DJ, Andrews, G, Slagboom, PE, Boomsma, DI and Martin, NG (2008). Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 150B (3), 352-358. doi: 10.1002/ajmg.b.30817

Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression

2008

Journal Article

Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands

Wray, Naomi R., Middeldorp, Christel M., Birley, Andrew J., Gordon, Scott D., Sullivan, Patrick F., Visscher, Peter M., Nyholt, Dale R, Willemsen, Gonneke, de Geus, Eco J.C., Slagboom, P. Eline, Montgomery, Grant W., Martin, Nicholas G. and Boomsma, Dorret I. (2008). Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands. Archives of General Psychiatry, 65 (6), 649-658. doi: 10.1001/archpsyc.65.6.649

Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands

2008

Journal Article

Association study of candidate variants of COMT with neuroticism, anxiety and depression

Wray, Naomi, James, Michael R., Dumenil, Troy, Handoko, Herlina Y., Lind, Penelope A., Montgomery, Grant W. and Martin, Nicholas G. (2008). Association study of candidate variants of COMT with neuroticism, anxiety and depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B (7), 1314-1318. doi: 10.1002/ajmg.b.30744

Association study of candidate variants of COMT with neuroticism, anxiety and depression

2008

Journal Article

A whole genome association study of neuroticism using DNA pooling

Shifman, S., Bhomra, A., Smiley, S., Wray, N. R., James, M. R., Martin, N. G., Hettema, J. M., An, S. S., Neale, M. C., van den Oord, E. J., Kendler, K. S., Chen, X., Boomsma, D. I., Middeldorp, C. M., Hottenga, J. J., Slagboom, P. E. and Flint, J. (2008). A whole genome association study of neuroticism using DNA pooling. Molecular Psychiatry, 13 (3), 302-312. doi: 10.1038/sj.mp.4002048

A whole genome association study of neuroticism using DNA pooling

2008

Journal Article

Prediction of individual genetic risk of complex disease

Wray, Naomi, Goddard, Michael E. and Visscher, Peter (2008). Prediction of individual genetic risk of complex disease. Current Opinion in Genetics and Development, 18 (3), 257-263. doi: 10.1016/j.gde.2008.07.006

Prediction of individual genetic risk of complex disease

2008

Journal Article

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression

Wray, Naomi R., James, Michael R., Handoko, Herlina Y., Dumenil, Troy, Lind, Penelope A., Montgomery, Grant W. and Martin, Nicholas G. (2008). Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression. Psychiatric Genetics, 18 (5), 219-225. doi: 10.1097/YPG.0b013e3283050aee

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression

2008

Journal Article

Shared temperament risk factors for anorexia nervosa: a twin study

Wade, T. D., Tiggemann, M., Bulik, C. M., Fairburn, C. G., Wray, N. R. and Martin, N. G. (2008). Shared temperament risk factors for anorexia nervosa: a twin study. Psychosomatic Medicine, 70 (2), 239-244. doi: 10.1097/PSY.0b013e31815c40f1

Shared temperament risk factors for anorexia nervosa: a twin study

2008

Journal Article

Heritability in the genomics era — concepts and misconceptions

Visscher, Peter, Hill, William G. and Wray, Naomi (2008). Heritability in the genomics era — concepts and misconceptions. Nature Reviews Genetics, 9 (4), 255-266. doi: 10.1038/nrg2322

Heritability in the genomics era — concepts and misconceptions

2007

Journal Article

Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus

Tomlinson, V. A. L., Newbery, H. J., Bergmann, J. H., Boyd, J., Scott, D., Wray, N. R., Sellar, G. C., Gabra, H., Graham, A., Williams, A. R. W. and Abbott, C. M. (2007). Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus. British Journal of Cancer, 96 (10), 1613-1620. doi: 10.1038/sj.bjc.6603748

Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus

2007

Journal Article

Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder

Le Hellard, Stephanie, Lee, Andrew J., Underwood, Sarah, Thomson, Pippa A., Morris, Stewart W., Torrance, Helen S., Anderson, Susan M., Adams, Richard R., Navarro, Pau, Christoforou, Andrea, Houlihan, Lorna M., Detera-Wadleigh, Sevilla, Owen, Michael J., Asherson, Philip, Muir, Walter I., Blackwood, Douglas H. R., Wray, Naomi R., Porteous, David I. and Evans, Kathryn L. (2007). Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder. Biological Psychiatry, 61 (6), 797-805. doi: 10.1016/j.biopsych.2006.06.029

Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder

2007

Journal Article

Anxiety and comorbid measures associated with PLXNA2

Wray, Naomi R., James, Michael R., Mah, Steven P., Nelson, Matthew, Andrews, Gavin, Sullivan, Patrick F., Montgomery, Grant W., Birley, Andrew J., Braun, Andreas and Martin, Nicholas G. (2007). Anxiety and comorbid measures associated with PLXNA2. Archives of General Psychiatry, 64 (3), 318-326. doi: 10.1001/archpsyc.64.3.318

Anxiety and comorbid measures associated with PLXNA2

2007

Journal Article

Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia

Christoforou, A., Le Hellard, S., Thomson, P. A., Morris, S. W., Tenesa, A., Pickard, B. S., Wray, N. R., Muir, W. J., Blackwood, D. H., Porteous, D. J. and Evans, K. L. (2007). Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia. Molecular Psychiatry, 12 (11), 1011-1025. doi: 10.1038/sj.mp.4002003

Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia

2007

Journal Article

Genetic and phenotypic stability of measures of neuroticism over 22 years

Wray, N. R., Birley, A. J., Sullivan, P. F., Visscher, P. M. and Martin, N. G. (2007). Genetic and phenotypic stability of measures of neuroticism over 22 years. Twin Research & Human Genetics, 10 (5), 695-702. doi: 10.1375/twin.10.5.695

Genetic and phenotypic stability of measures of neuroticism over 22 years

2007

Journal Article

Prediction of individual genetic risk to disease from genome-wide association studies

Wray, Naomi R., Goddard, Michael E. and Visscher, Peter M. (2007). Prediction of individual genetic risk to disease from genome-wide association studies. Genome Research, 17 (10), 1520-1528. doi: 10.1101/gr.6665407

Prediction of individual genetic risk to disease from genome-wide association studies

2006

Journal Article

Empirical Evaluation of the Genetic Similarity of Samples From Twin Registries in Australia and the Netherlands Using 359 STRP Markers

Sullivan, Patrick F., Montgomery, Grant W., Hottenga, Jouke J., Wray, Naomi R., Boomsma, Dorret I. and Martin, Nicholas G. (2006). Empirical Evaluation of the Genetic Similarity of Samples From Twin Registries in Australia and the Netherlands Using 359 STRP Markers. Twin Research And Human Genetics, 9 (4), 600-602. doi: 10.1375/183242706778025026

Empirical Evaluation of the Genetic Similarity of Samples From Twin Registries in Australia and the Netherlands Using 359 STRP Markers

2006

Journal Article

Sex Differences in Symptoms of Depression in Unrelated Individuals and Opposite-Sex Twin and Sibling Pairs

Middeldorp, Christel M., Wray, Naomi R., Andrews, Gavin, Martin, Nicholas G. and Boomsma, Dorret I. (2006). Sex Differences in Symptoms of Depression in Unrelated Individuals and Opposite-Sex Twin and Sibling Pairs. Twin Research And Human Genetics, 9 (5), 632-636. doi: 10.1375/183242706778553507

Sex Differences in Symptoms of Depression in Unrelated Individuals and Opposite-Sex Twin and Sibling Pairs