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2024 Journal Article An automated and robust tool for musculoskeletal and finite element modeling of the knee jointEsrafilian, Amir, Chandra, Shekhar S., Gatti, Anthony A., Nissi, Mikko, Mustonen, Anne-Mari, Saisanen, Laura, Reijonen, Jusa, Nieminen, Petteri, Julkunen, Petro, Toyras, Juha, Saxby, David J., Lloyd, David G. and Korhonen, Rami K. (2024). An automated and robust tool for musculoskeletal and finite element modeling of the knee joint. IEEE Transactions on Biomedical Engineering, 72 (1), 1-13. doi: 10.1109/tbme.2024.3438272 |
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2024 Journal Article “An excellent servant but a terrible master”: understanding the value of wearables for self-management in people with cystic fibrosis and their healthcare providers – a qualitative studyMattison, Graeme, Canfell, Oliver J., Smith, Daniel, Forrester, Doug, Reid, David, Töyräs, Juha and Dobbins, Chelsea (2024). “An excellent servant but a terrible master”: understanding the value of wearables for self-management in people with cystic fibrosis and their healthcare providers – a qualitative study. International Journal of Medical Informatics, 189 105532, 105532. doi: 10.1016/j.ijmedinf.2024.105532 |
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2024 Journal Article Relationship between depth-wise refractive index and biomechanical properties of human articular cartilageKhan, Bilour, Nippolainen, Ervin, Shahini, Fatemeh, Nonappa,, Popov, Alexey, Töyräs, Juha and Afara, Isaac O. (2024). Relationship between depth-wise refractive index and biomechanical properties of human articular cartilage. Journal of biomedical optics, 29 (9) 095003, 095003. doi: 10.1117/1.JBO.29.9.095003 |
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2024 Journal Article Estimation of photon path length and penetration depth in articular cartilage zonal architecture over the therapeutic windowKafian-Attari, I., Nippolainen, E., Bergmann, F., George, A., Paakkari, P., Mirhashemi, A., Foschum, F., Kienle, A., Toyras, J. and Afara, I. O. (2024). Estimation of photon path length and penetration depth in articular cartilage zonal architecture over the therapeutic window. IEEE Transactions on Biomedical Engineering, 71 (8), 2300-2310. doi: 10.1109/TBME.2024.3368012 |
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2024 Journal Article Infrared spectroscopy can differentiate between cartilage injury models: implication for assessment of cartilage integrityShahini, Fatemeh, Oskouei, Soroush, Nippolainen, Ervin, Mohammadi, Ali, Sarin, Jaakko K., Moller, Nikae C. R. te, Brommer, Harold, Shaikh, Rubina, Korhonen, Rami K., van Weeren, P. René, Töyräs, Juha and Afara, Isaac O. (2024). Infrared spectroscopy can differentiate between cartilage injury models: implication for assessment of cartilage integrity. Annals of Biomedical Engineering, 52 (9), 2521-2533. doi: 10.1007/s10439-024-03540-x |
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2024 Journal Article Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: potential and challenges for diagnosing osteoarthritisKrebs, P., Nägele, M., Fomina, P., Virtanen, V., Nippolainen, E., Shaikh, R., Afara, I. O., Töyräs, J., Usenov, I., Sakharova, T., Artyushenko, V., Tafintseva, V., Solheim, J.H., Zimmermann, B., Kohler, A., König, O., Saarakkala, S. and Mizaikoff, B. (2024). Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: potential and challenges for diagnosing osteoarthritis. Osteoarthritis and Cartilage Open, 6 (2) 100466, 100466. doi: 10.1016/j.ocarto.2024.100466 |
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2024 Journal Article Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apneaChen, Xin, Leppänen, Timo, Kainulainen, Samu, Howarth, Timothy P., Oksenberg, Arie, Töyräs, Juha, Terrill, Philip I. and Korkalainen, Henri (2024). Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apnea. Journal of Clinical Sleep Medicine, 20 (10), 1595-1606. doi: 10.5664/jcsm.11198 |
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2024 Journal Article Site-specific elastic and viscoelastic biomechanical properties of healthy and osteoarthritic human knee joint articular cartilageLinus, Awuniji, Tanska, Petri, Nippolainen, Ervin, Tiitu, Virpi, Töyras, Juha, Korhonen, Rami K., Afara, Isaac O. and Mononen, Mika E. (2024). Site-specific elastic and viscoelastic biomechanical properties of healthy and osteoarthritic human knee joint articular cartilage. Journal of Biomechanics, 169 112135, 112135. doi: 10.1016/j.jbiomech.2024.112135 |
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2024 Journal Article Increased flow limitation during sleep is associated with increased psychomotor vigilance task lapses in individuals with suspected obstructive sleep apneaStaykov, Eric, Mann, Dwayne L., Duce, Brett, Kainulainen, Samu, Leppänen, Timo, Töyräs, Juha, Azarbarzin, Ali, Georgeson, Thomas, Sands, Scott A. and Terrill, Philip I. (2024). Increased flow limitation during sleep is associated with increased psychomotor vigilance task lapses in individuals with suspected obstructive sleep apnea. CHEST, 165 (4), 990-1003. doi: 10.1016/j.chest.2023.11.031 |
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2024 Journal Article Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apneaPahari, Purbanka, Korkalainen, Henri, Karhu, Tuomas, Arnardottir, Erna Sif, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2024). Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea. Journal of Sleep Research, 33 (2) e13988, e13988. doi: 10.1111/jsr.13988 |
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2024 Journal Article Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxemia in sleep apnea patientsPahari, Purbanka, Korkalainen, Henri, Arnardóttir, Erna Sif, Islind, Anna Sigridur, August, Elias, Oksenberg, Arie, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2024). Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxemia in sleep apnea patients. ERJ Open Research, 10 (4) 01051-2023, 1-12. doi: 10.1183/23120541.01051-2023 |
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2024 Journal Article Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patientsEbrahimian, Serajeddin, Sillanmäki, Saara, Hietakoste, Salla, Kulkas, Antti, Töyräs, Juha, Bailon, Raquel, Hernando, David, Lombardi, Carolina, Grote, Ludger, Bonsignore, Maria R, Saaresranta, Tarja, Pépin, Jean-Louis, Leppänen, Timo and Kainulainen, Samu (2024). Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients. American Journal of Physiology-Heart and Circulatory Physiology, 326 (5), H1094-H1104. doi: 10.1152/ajpheart.00760.2023 |
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2024 Journal Article Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterationsJäntti, Jiri, Joenathan, Anisha, Fugazzola, Maria, Tuppurainen, Juuso, Honkanen, Juuso T. J., Töyräs, Juha, van Weeren, René, Snyder, Brian D., Grinstaff, Mark W., Matikka, Hanna and Mäkelä, Janne T.A. (2024). Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations. Osteoarthritis and Cartilage, 32 (3), 299-309. doi: 10.1016/j.joca.2023.11.020 |
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2024 Journal Article Variation in the photoplethysmogram response to arousal from sleep depending on the cause of arousal and the presence of desaturationLuukinen, Mieli, Pitkänen, Henna, Leppänen, Timo, Töyräs, Juha, Islind, Anna Sigridur, Kainulainen, Samu and Korkalainen, Henri (2024). Variation in the photoplethysmogram response to arousal from sleep depending on the cause of arousal and the presence of desaturation. IEEE Journal of Translational Engineering in Health and Medicine, 12, 328-339. doi: 10.1109/jtehm.2024.3349916 |
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2024 Journal Article Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—A proof of concept studyOrava, Heta, Paakkari, Petri, Jäntti, Jiri, Honkanen, Miitu K. M., Honkanen, Juuso T. J., Virén, Tuomas, Joenathan, Anisha, Tanska, Petri, Korhonen, Rami K., Grinstaff, Mark W., Töyräs, Juha and Mäkelä, Janne T. A. (2024). Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—A proof of concept study. Journal of Orthopaedic Research, 42 (2), 415-424. doi: 10.1002/jor.25683 |
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2024 Journal Article Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemiaHietakoste, Salla, Armañac-Julián, Pablo, Karhu, Tuomas, Bailón, Raquel, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia. IEEE Transactions on Biomedical Engineering, 71 (1), 326-333. doi: 10.1109/tbme.2023.3300079 |
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2023 Journal Article Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea indexPitkänen, Minna, Nath, Rajdeep Kumar, Korkalainen, Henri, Nikkonen, Sami, Mahamid, Alaa, Oksenberg, Arie, Duce, Brett, Töyräs, Juha, Kainulainen, Samu and Leppänen, Timo (2023). Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index. Sleep Advances, 5 (1) zpad054, 1-9. doi: 10.1093/sleepadvances/zpad054 |
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2023 Journal Article Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrixKafian-Attari, Iman, Nippolainen, Ervin, Bergmann, Florian, George, Akuroma, Paakkari, Petri, Mirhashemi, Arash, Foschum, Florian, Kienle, Alwin, Töyräs, Juha and Afara, Isaac O. (2023). Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix. Journal of biomedical optics, 28 (12) 125003, 1-16. doi: 10.1117/1.JBO.28.12.125003 |
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2023 Journal Article 3D T<sub>1</sub> relaxation time measurements in an equine model of subtle post‐traumatic osteoarthritis using MB‐SWIFTPala, Swetha, Hänninen, Nina E., Mohammadi, Ali, Ebrahimi, Mohammadhossein, te Moller, Nikae C. R., Brommer, Harold, René van Weeren, P., Mäkelä, Janne T. A., Korhonen, Rami K., Afara, Isaac O., Töyräs, Juha, Mikkonen, Santtu, Nissi, Mikko J. and Nykänen, Olli (2023). 3D T1 relaxation time measurements in an equine model of subtle post‐traumatic osteoarthritis using MB‐SWIFT. Journal of Orthopaedic Research, 41 (12), 2657-2666. doi: 10.1002/jor.25629 |
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2023 Journal Article Review and perspective on sleep-disordered breathing research and translation to clinicsKorkalainen, Henri, Kainulainen, Samu, Islind, Anna Sigridur, Óskarsdóttir, María, Strassberger, Christian, Nikkonen, Sami, Töyräs, Juha, Kulkas, Antti, Grote, Ludger, Hedner, Jan, Sund, Reijo, Hrubos-Strom, Harald, Saavedra, Jose M., Ólafsdóttir, Kristín Anna, Ágústsson, Jón S., Terrill, Philip I., McNicholas, Walter T., Arnardóttir, Erna Sif, Leppänen, Timo and On behalf of SLEEP REVOLUTION (2023). Review and perspective on sleep-disordered breathing research and translation to clinics. Sleep Medicine Reviews, 73 101874, 1-12. doi: 10.1016/j.smrv.2023.101874 |