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2019

Journal Article

Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania

Menegas, Samira, Dal-Pont, Gustavo C., Cararo, José H., Varela, Roger B., Aguiar-Geraldo, Jorge M., Possamai-Della, Taise, Andersen, Monica L., Quevedo, João and Valvassori, Samira S. (2019). Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania. Metabolic Brain Disease, 35 (2), 413-425. doi: 10.1007/s11011-019-00503-3

Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania

2019

Journal Article

Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats

Valvassori, Samira S., Tonin, Paula T., Dal-Pont, Gustavo C., Varela, Roger B., Cararo, José Henrique, Garcia, Abel Freitas, Gava, Fernanda F., Menegas, Samira, Soares, Jair C. and Quevedo, João (2019). Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats. Translational Psychiatry, 9 (1) 297, 1-11. doi: 10.1038/s41398-019-0637-9

Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats

2019

Journal Article

Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania

Valvassori, Samira S., Dal-Pont, Gustavo C., Tonin, Paula T., Varela, Roger B., Ferreira, Camila L., Gava, Fernanda F., Andersen, Monica L., Soares, Jair C. and Quevedo, Joao (2019). Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania. Pharmacology, Biochemistry and Behavior, 183, 56-63. doi: 10.1016/j.pbb.2019.05.009

Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania

2019

Journal Article

Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives

Valvassori, Samira S., Dal-Pont, Gustavo C., Resende, Wilson R., Varela, Roger B., Lopes-Borges, Jessica, Cararo, Jose Henrique and Quevedo, Joao (2019). Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives. Translational Psychiatry, 9 (1) 158. doi: 10.1038/s41398-019-0494-6

Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives

2019

Journal Article

Tamoxifen has an anti-manic effect but not protect the brain against oxidative stress in an animal model of mania induced by ouabain

Dal-Pont, Gustavo C., Resende, Wilson R., Bianchini, Guilherme, Gava, Fernanda F., Peterle, Bruna R., Trajano, Kerolen S., Varela, Roger B., Quevedo, Joao and Valvassori, Samira S. (2019). Tamoxifen has an anti-manic effect but not protect the brain against oxidative stress in an animal model of mania induced by ouabain. Journal of Psychiatric Research, 113, 181-189. doi: 10.1016/j.jpsychires.2019.03.020

Tamoxifen has an anti-manic effect but not protect the brain against oxidative stress in an animal model of mania induced by ouabain

2019

Journal Article

Inhibition of GSK-3β on behavioral changes and oxidative stress in an animal model of mania

Dal-Pont, Gustavo C., Resende, Wilson R., Varela, Roger B., Menegas, Samira, Trajano, Kerolen S., Peterle, Bruna R., Quevedo, Joao and Valvassori, Samira S. (2019). Inhibition of GSK-3β on behavioral changes and oxidative stress in an animal model of mania. Molecular Neurobiology, 56 (4), 2379-2393. doi: 10.1007/s12035-018-1226-2

Inhibition of GSK-3β on behavioral changes and oxidative stress in an animal model of mania

2019

Journal Article

The role of neurotrophic factors in manic-, anxious- and depressive-like behaviors induced by amphetamine sensitization: implications to the animal model of bipolar disorder

Valvassori, Samira S., Mariot, Edemilson, Varela, Roger B., Bavaresco, Daniela V., Dal-Pont, Gustavo C., Ferreira, Camila L., Andersen, Monica L., Tye, Susannah J. and Quevedo, João (2019). The role of neurotrophic factors in manic-, anxious- and depressive-like behaviors induced by amphetamine sensitization: implications to the animal model of bipolar disorder. Journal of Affective Disorders, 245, 1106-1113. doi: 10.1016/j.jad.2018.10.370

The role of neurotrophic factors in manic-, anxious- and depressive-like behaviors induced by amphetamine sensitization: implications to the animal model of bipolar disorder

2018

Journal Article

Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of D-galactose

Garcez, Michelle Lima, de Carvalho, Carlos Alberto, Mina, Francielle, Bellettini-Santos, Tatiani, Schiavo, Gustavo Luis, da Silva, Sabrina, Campos, Ana Carolina Brunatto Falchetti, Varela, Roger Bitencourt, Valvassori, Samira S., Damiani, Adriani Paganini, Longaretti, Luiza Martins, de Andrade, Vanessa Moraes and Budni, Josiane (2018). Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of D-galactose. Experimental Gerontology, 113, 209-217. doi: 10.1016/j.exger.2018.10.005

Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of D-galactose

2018

Journal Article

Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels

Valvassori, Samira S., Borges, Cenita, Bavaresco, Daniela V., Varela, Roger B., Resende, Wilson R., Peterle, Bruna R., Arent, Camila O., Budni, Josiane and Quevedo, João (2018). Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels. Revista Brasileira de Psiquiatria, 40 (4), 367-375. doi: 10.1590/1516-4446-2017-2271

Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels

2018

Journal Article

Increased oxidative stress in the mitochondria isolated from lymphocytes of bipolar disorder patients during depressive episodes

Valvassori, Samira S., Bavaresco, Daniela V., Feier, Gustavo, Cechinel-Recco, Kelen, Steckert, Amanda V., Varela, Roger B., Borges, Cenita, Carvalho-Silva, Milena, Gomes, Lara M., Streck, Emílio L. and Quevedo, João (2018). Increased oxidative stress in the mitochondria isolated from lymphocytes of bipolar disorder patients during depressive episodes. Psychiatry Research, 264, 192-201. doi: 10.1016/j.psychres.2018.03.089

Increased oxidative stress in the mitochondria isolated from lymphocytes of bipolar disorder patients during depressive episodes

2018

Journal Article

The Effects of Histone Deacetylase Inhibition on the Levels of Cerebral Cytokines in an Animal Model of Mania Induced by Dextroamphetamine

Valvassori, Samira S., Resende, Wilson R., Varela, Roger B., Arent, Camila O., Gava, Fernanda F., Peterle, Bruna R., Dal-Pont, Gustavo C., Carvalho, André F., Andersen, Monica L. and Quevedo, João (2018). The Effects of Histone Deacetylase Inhibition on the Levels of Cerebral Cytokines in an Animal Model of Mania Induced by Dextroamphetamine. Molecular Neurobiology, 55 (2), 1430-1439. doi: 10.1007/s12035-017-0384-y

The Effects of Histone Deacetylase Inhibition on the Levels of Cerebral Cytokines in an Animal Model of Mania Induced by Dextroamphetamine

2017

Journal Article

Lithium and tamoxifen modulate behavior and Protein Kinase C activity in the animal model of mania induced by ouabain

Valvassori, Samira S., Dal-Pont, Gustavo C., Resende, Wilson R., Varela, Roger B., Peterle, Bruna R., Gava, Fernanda F., Mina, Francielle G., Cararo, José H., Carvalho, André F. and Quevedo, João (2017). Lithium and tamoxifen modulate behavior and Protein Kinase C activity in the animal model of mania induced by ouabain. International Journal of Neuropsychopharmacology, 20 (11), 877-885. doi: 10.1093/ijnp/pyx049

Lithium and tamoxifen modulate behavior and Protein Kinase C activity in the animal model of mania induced by ouabain

2017

Journal Article

The different effects of lithium and tamoxifen on memory formation and the levels of neurotrophic factors in the brain of male and female rats

Valvassori, Samira S., Borges, Cenita P., Varela, Roger B., Bavaresco, Daniela V., Bianchini, Guilherme, Mariot, Edemilson, Arent, Camila O., Resende, Wilson R., Budni, Josiane and Quevedo, João (2017). The different effects of lithium and tamoxifen on memory formation and the levels of neurotrophic factors in the brain of male and female rats. Brain Research Bulletin, 134, 228-235. doi: 10.1016/j.brainresbull.2017.08.006

The different effects of lithium and tamoxifen on memory formation and the levels of neurotrophic factors in the brain of male and female rats

2017

Book Chapter

Animal models of mood disorders: focus on bipolar disorder and depression

Valvassori, Samira S., Varela, Roger B. and Quevedo, João (2017). Animal models of mood disorders: focus on bipolar disorder and depression. Animal models for the study of human disease. (pp. 991-1001) edited by P. Michael Conn. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-809468-6.00038-3

Animal models of mood disorders: focus on bipolar disorder and depression

2017

Journal Article

Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic-pituitary-adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice

Valvassori, Samira S., Resende, Wilson R., Dal-Pont, Gustavo, Sangaletti-Pereira, Heron, Gava, Fernanda F., Peterle, Bruna R., Carvalho, André F., Varela, Roger B., Dal-Pizzol, Felipe and Quevedo, João (2017). Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic-pituitary-adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice. Bipolar Disorders, 19 (4), 246-258. doi: 10.1111/bdi.12503

Lithium ameliorates sleep deprivation-induced mania-like behavior, hypothalamic-pituitary-adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice

2015

Journal Article

Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania

Fries, Gabriel R., Valvassori, Samira S., Bock, Hugo, Stertz, Laura, Magalhães, Pedro Vieira da Silva, Mariot, Edimilson, Varela, Roger B., Kauer-Sant'Anna, Marcia, Quevedo, João, Kapczinski, Flávio and Saraiva-Pereira, Maria Luiza (2015). Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania. Journal of Psychiatric Research, 68, 329-336. doi: 10.1016/j.jpsychires.2015.05.006

Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania

2015

Journal Article

Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania

Valvassori, Samira S., Arent, Camila O., Steckert, Amanda V., Varela, Roger B., Jornada, Luciano K., Tonin, Paula T., Budni, Josiane, Mariot, Edemilson, Kapczinski, Flávio and Quevedo, João (2015). Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania. Molecular Neurobiology, 52 (1), 353-362. doi: 10.1007/s12035-014-8873-8

Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania

2015

Journal Article

Effects of palatable cafeteria diet on cognitive and noncognitive behaviors and brain neurotrophins’ levels in mice

Leffa, Daniela D., Valvassori, Samira S., Varela, Roger B., Lopes-Borges, Jésica, Daumann, Francine, Longaretti, Luiza M., Dajori, Ana Luiza F., Quevedo, João and Andrade, Vanessa M. (2015). Effects of palatable cafeteria diet on cognitive and noncognitive behaviors and brain neurotrophins’ levels in mice. Metabolic Brain Disease, 30 (4), 1073-1082. doi: 10.1007/s11011-015-9682-0

Effects of palatable cafeteria diet on cognitive and noncognitive behaviors and brain neurotrophins’ levels in mice

2015

Journal Article

Lithium modulates the production of peripheral and cerebral cytokines in an animal model of mania induced by dextroamphetamine

Valvassori, Samira S., Tonin, Paula T., Varela, Roger B., Carvalho, André F., Mariot, Edemilson, Amboni, Rafaela T., Bianchini, Guilherme, Andersen, Monica L. and Quevedo, João (2015). Lithium modulates the production of peripheral and cerebral cytokines in an animal model of mania induced by dextroamphetamine. Bipolar Disorders, 17 (5), 507-517. doi: 10.1111/bdi.12299

Lithium modulates the production of peripheral and cerebral cytokines in an animal model of mania induced by dextroamphetamine

2015

Journal Article

Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain

Valvassori, Samira S., Dal-Pont, Gustavo C., Steckert, Amanda V., Varela, Roger B., Lopes-Borges, Jéssica, Mariot, Edemilson, Resende, Wilson R., Arent, Camila O., Carvalho, André F. and Quevedo, João (2015). Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. Psychiatry Research, 235, 154-159. doi: 10.1016/j.psychres.2015.11.017

Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain