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2013 Journal Article Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1Rao, Tara, Ruiz-Gomez, Gloria, Hill, Timothy A., Hoang, Huy N., Fairlie, David P. and Mason, Jody M. (2013). Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1. PLoS One, 8 (3) e59415, e59415.1-e59415.12. doi: 10.1371/journal.pone.0059415 |
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2013 Journal Article C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signalingLiu, Junxian, Iyer, Abishek, Suen, Jacky Y., Seow, Vernon, Reid, Robert C., Brown, Lindsay and Fairlie, David P. (2013). C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling. The FASEB Journal, 27 (2), 822-831. doi: 10.1096/fj.12-220582 |
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2013 Journal Article Efficient chemical synthesis of human complement protein C3aGhassemian, Artin, Wang, Ching-I Anderson, Yau, Mei-Kwan, Reid, Robert C., Lewis, Richard J., Fairlie, David P., Alewood, Paul F. and Durek, Thomas (2013). Efficient chemical synthesis of human complement protein C3a. Chemical Communications, 49 (23), 2356-2358. doi: 10.1039/c3cc40537k |
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2013 Journal Article The Future of Peptide-based DrugsCraik, David J., Fairlie, David P., Liras, Spiros and Price, David (2013). The Future of Peptide-based Drugs. Chemical Biology and Drug Design, 81 (1), 136-147. doi: 10.1111/cbdd.12055 |
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2013 Journal Article Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide ANielsen, Daniel S., Hoang, Huy N., Lohman, Rink-Jan, Diness, Frederik and Fairlie, David P. (2013). Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A. Organic Letters, 14 (22), 5720-5723. doi: 10.1021/ol3027347 |
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2012 Journal Article MR1 presents microbial vitamin B metabolites to MAIT cellsKjer-Nielsen, Lars, Patel, Onisha, Corbett, Alexandra J., Le Nours, Jerome, Meehan, Bronwyn, Liu, Ligong, Bhati, Mugdha, Chen, Zhenjun, Kostenko, Lyudmila, Reantragoon, Rangsima, Williamson, Nicholas A., Purcell, Anthony W., Dudek, Nadine L., McConville, Malcolm J., O'Hair, Richard A. J., Khairallah, George N., Godfrey, Dale I., Fairlie, David P., Rossjohn, Jamie and McCluskey, James (2012). MR1 presents microbial vitamin B metabolites to MAIT cells. Nature, 491 (7426), 717-725. doi: 10.1038/nature11605 |
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2012 Journal Article Targeting quorum sensing and competence stimulation for antimicrobial chemotherapyShepherd, Nicholas E., Harrison, Rosemary S. and Fairlie, David P. (2012). Targeting quorum sensing and competence stimulation for antimicrobial chemotherapy. Current Drug Targets, 13 (11), 1348-1359. doi: 10.2174/138945012803530233 |
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2012 Journal Article An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in ratsIyer, Abishek, Lim, Junxian, Poudyal, Hemant, Reid, Robert C., Suen, Jacky Y., Webster, Julie, Prins, Johannes B., Whitehead, Jonathan P., Fairlie, David P. and Brown, Lindsay (2012). An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats. Diabetes, 61 (9), 2320-2329. doi: 10.2337/db11-1179 |
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2012 Journal Article Catalyst-free N-arylation using unactivated fluorobenzenesDiness, Frederik and Fairlie, David (2012). Catalyst-free N-arylation using unactivated fluorobenzenes. Angewandte Chemie International Edition, 51 (32), 8012-8016. doi: 10.1002/anie.201202149 |
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2012 Journal Article A comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly Gi coupled GPCR (C5aR) signallingHalai, Reena, Croker, Daniel E., Suen, Jacky Y., Fairlie, David P. and Cooper, Matthew A. (2012). A comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly Gi coupled GPCR (C5aR) signalling. Biosensors, 2 (3), 273-290. doi: 10.3390/bios2030273 |
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2012 Journal Article Antimalarial activity of the anticancer histone deacetylase inhibitor SB939Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P. and Andrews, Katherine T. (2012). Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. Antimicrobial Agents and Chemotherapy, 56 (7), 3849-3856. doi: 10.1128/AAC.00030-12 |
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2012 Journal Article An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in ratsLohman, Rink-Jan, Cotterell, Adam J., Barry, Grant D., Liu, Ligong, Suen, Jacky Y., Vesey, David A. and Fairlie, David P. (2012). An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. The FASEB Journal, 26 (7), 2877-2887. doi: 10.1096/fj.11-201004 |
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2012 Journal Article Chemical biology down underFairlie, David (2012). Chemical biology down under. Current Topics in Medicinal Chemistry, 12 (14), 1469-1470. doi: 10.2174/156802612802652475 |
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2012 Journal Article Towards isozyme-selective HDA inhibitors for interrogating diseaseGupta, Praveer, Reid, Robert C., Iyer, Abishek, Sweet, Matthew J. and Fairlie, David (2012). Towards isozyme-selective HDA inhibitors for interrogating disease. Current Topics in Medicinal Chemistry, 12 (14), 1479-1499. doi: 10.2174/156802612802652420 |
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2012 Journal Article Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseasesCantley, Melissa D., Bartold, Peter M., Fairlie, David P., Rainsford, K. D. and Haynes, David R. (2012). Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases. Journal of Pharmacy and Pharmacology, 64 (6), 763-774. doi: 10.1111/j.2042-7158.2011.01421.x |
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2012 Journal Article Folding pentapeptides into left and right handed alpha helicesHoang, Huy N., Abbenante, Giovanni, Hill, Timothy A., Ruiz-Gomez, Gloria and Fairlie, David P. (2012). Folding pentapeptides into left and right handed alpha helices. Tetrahedron, 68 (23), 4513-4516. doi: 10.1016/j.tet.2011.10.108 |
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2012 Journal Article Matching cavities in G protein-coupled receptors to infer ligand-binding sitesMadala, Praveen K., Fairlie, David P. and Bodén, Mikael (2012). Matching cavities in G protein-coupled receptors to infer ligand-binding sites. Journal of Chemical Information and Modeling, 52 (5), 1401-1410. doi: 10.1021/ci2005498 |
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2012 Journal Article C5a receptor (CD88) and TLR2 inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic modelThundyil, John, Pavlovski, Dale, Hsieh, Yu-Hsuan, Gelderblom, Mathias, Magnus, Tim, Fairlie, David P. and Arumugam, Thiruma V. (2012). C5a receptor (CD88) and TLR2 inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model. NeuroMolecular Medicine, 14 (1), 30-39. doi: 10.1007/s12017-012-8167-0 |
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2012 Journal Article Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)Suen, J. Y., Barry, G. D., Lohman, R. J., Halili, M. A., Cotterell, A. J., Le, G. T. and Fairlie, D. P. (2012). Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). British Journal of Pharmacology, 165 (5), 1413-1423. doi: 10.1111/j.1476-5381.2011.01610.x |
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2012 Journal Article Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitorsAndrews, Katherine T., Gupta, Archna P., Tran, Thanh N., Fairlie, David P., Gobert, Geoffrey N. and Bozdech, Zbynek (2012). Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors. Plos One, 7 (2) e31847, e31847-1-e31847-9. doi: 10.1371/journal.pone.0031847 |
