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2010 Journal Article Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structureRuiz-Gomez, Gloria, Tyndall, Joel D. A., Pfeiffer, Bernhard, Abbenante, Giovanni and Fairlie, David (2010). Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure. Chemical Reviews, 110 (6), 1-41. doi: 10.1021/cr900344w |
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2010 Journal Article Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive ratsIyer, Abishek, Fenning, Andrew, Lim, Junxian, Le, Giang T, Reid, Robert C, Halili, Maria A, Fairlie, David P and Brown, Lindsay (2010). Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. British Journal of Pharmacology, 159 (7), 1408-1417. doi: 10.1111/j.1476-5381.2010.00637.x |
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2010 Journal Article Update 1 of: Over One Hundred Petide-Activated G Protein-Coupled Receptors Recognized Ligands with Turn StructureRuiz-Gomez, Gloria, Tyndall, Joel D. A., Pfeiffer, Bernhard, Abbenante, Giovanni and Fairlie, David P. (2010). Update 1 of: Over One Hundred Petide-Activated G Protein-Coupled Receptors Recognized Ligands with Turn Structure. Chemical Reviews, 110 (4), PR1-PR41. |
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2010 Journal Article Noncovalent tripeptidyl benzyl- And cyclohexyl-amine inhibitors of the cysteine protease caspase-1Loser, Reik, Abbenante, Giovanni, Madala, Praveen K., Halili, Maria, Le, Giang T. and Fairlie, David P. (2010). Noncovalent tripeptidyl benzyl- And cyclohexyl-amine inhibitors of the cysteine protease caspase-1. Journal of Medicinal Chemistry, 53 (6), 2651-2655. doi: 10.1021/jm901790w |
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2010 Journal Article Inflammatory lipid mediators in adipocyte function and obesityIyer, Abishek, Fairlie, David P., Prins, Johannes B., Hammock, Bruce D. and Brown, Lindsay (2010). Inflammatory lipid mediators in adipocyte function and obesity. Nature Reviews Endocrinology, 6 (2), 71-82. doi: 10.1038/nrendo.2009.264 |
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2009 Journal Article In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flavivirusesKampmann, T., Yennamalli, R., Campbell, P., Stoermer, M. J., Fairlie, D. P., Kobe, B. and Young, P. R. (2009). In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses. Antiviral Research, 84 (3), 234-241. doi: 10.1016/j.antiviral.2009.09.007 |
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2009 Journal Article Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffoldsShepherd, N. E., Hoang, H. N., Abbenante, G and Fairlie, D. P. (2009). Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds. Journal of the American Chemical Society, 131 (43), 15877-15886. doi: 10.1021/ja9065283 |
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2009 Journal Article Structure-activity relationships for substrate-based inhibitors of human complement factor BRuiz-Gomez, G, Lim, J, Halili, M. A., Le, G. T., Madala, P. K., Abbenante, G and Fairlie, D. P. (2009). Structure-activity relationships for substrate-based inhibitors of human complement factor B. JOURNAL OF MEDICINAL CHEMISTRY, 52 (19), 6042-6052. doi: 10.1021/jm900781m |
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2009 Journal Article Base-sensitivity of arginine alpha-ketoamide inhibitors of serine proteasesStoermer, Martin J., Leung, Donmienne, Young, Paul R. and Fairlie, David P. (2009). Base-sensitivity of arginine alpha-ketoamide inhibitors of serine proteases. Australian Journal of Chemistry, 62 (9), 988-992. doi: 10.1071/CH09150 |
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2009 Journal Article A cyclic beta-strand tripeptide with an alpha-helix like CD spectrumDriver, Russell W., Hoang, Huy N., Abbenante, Giovanni and Fairlie, David P. (2009). A cyclic beta-strand tripeptide with an alpha-helix like CD spectrum. Organic Letters, 11 (14), 3092-3095. doi: 10.1021/ol901181b |
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2009 Journal Article Metal clips that induce unstructured pentapeptides to be alpha-Helical in waterMa, Michelle T., Hoang, Huy N., Scully, Conor C. G., Appleton, Trevor G. and Fairlie, David P. (2009). Metal clips that induce unstructured pentapeptides to be alpha-Helical in water. Journal of the American Chemical Society, 131 (12), 4505-4512. doi: 10.1021/ja900047w |
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2009 Journal Article The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitisCantley, M. D., Bartold, P. M., Marino, V, Reid, R. C., Fairlie, D. P., Wyszynski, R. N., Zilm, P. S. and Haynes, D. R. (2009). The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis. Journal of Periodontal Research, 44 (3), 317-322. doi: 10.1111/j.1600-0765.2008.01132.x |
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2009 Journal Article Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformationRobin, Gautier, Chappell, Keith, Stoermer, Martin J., Hu, Shu-Hong, Young, Paul R., Fairlie, David P. and Martin, Jennifer L. (2009). Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation. Journal of Molecular Biology, 385 (5), 1568-1577. doi: 10.1016/j.jmb.2008.11.026 |
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2009 Journal Article Histone deacetylase inhibitors in inflammatory diseaseHalili, M. A., Andrews, M, Sweet, M. and Fairlie, D. P. (2009). Histone deacetylase inhibitors in inflammatory disease. Current Topics in Medicinal Chemistry, 9 (3), 309-319. doi: 10.2174/156802609788085250 |
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2009 Journal Article Targeting histone deacetylase inhibitors for anti-malarial therapyAndrews, K. T, Tran, T. N., Wheatley, N. and Fairlie, David (2009). Targeting histone deacetylase inhibitors for anti-malarial therapy. Current Topics in Medicinal Chemistry, 9 (3), 292-308. doi: 10.2174/156802609788085313 |
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2009 Journal Article Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activationHalili, Maria A., Ruiz-Gomez, Gloria, Le, Giang T., Abbenante, Giovanni and Fairlie, David P. (2009). Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. Biochemistry, 48 (35), 8466-8472. doi: 10.1021/bi900679r |
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2008 Journal Article West Nile Virus NS2B/NS3 protease as an antiviral targetChappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2008). West Nile Virus NS2B/NS3 protease as an antiviral target. Current Medicinal Chemistry, 15 (27), 2771-2784. doi: 10.2174/092986708786242804 |
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2008 Journal Article Linkage isomerism in the binding of pentapeptide Ac-His(ALA)3His-NH2 to (Ethylenediamine)Palladium(II): Effect of the binding mode on peptide conformationHoang, H.N., Bryant, G.K., Kelso, M.J., Beyer, R.L., Appleton, T.G. and Fairlie, D.P. (2008). Linkage isomerism in the binding of pentapeptide Ac-His(ALA)3His-NH2 to (Ethylenediamine)Palladium(II): Effect of the binding mode on peptide conformation. Inorganic Chemistry, 47 (20), 9439-9449. doi: 10.1021/ic800970p |
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2008 Journal Article Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activityStoermer, Martin J., Chappell, Keith J., Liebscher, Susann, Jensen, Christina M., Gan, Chun H., Gupta, Praveer K., Xu, Wei-Jun, Young, Paul R. and Fairlie, David P. (2008). Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity. Journal of Medicinal Chemistry, 51 (18), 5714-5721. doi: 10.1021/jm800503y |
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2008 Journal Article Cyclooligomerization of a helix-bearing template into macrocycles bearing multiple helicesBeyer, Rene´e L., Singh, Yogendra and Fairlie, David P. (2008). Cyclooligomerization of a helix-bearing template into macrocycles bearing multiple helices. Organic Letters, 10 (16), 3481-3484. doi: 10.1021/ol801040c |
