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1999 Journal Article The possible origin of free radicals from amyloid peptides in Alzheimer's diseaseBush, A. I., Huang, X. and Fairlie, D. (1999). The possible origin of free radicals from amyloid peptides in Alzheimer's disease. Neurobiology of Aging, 20 (3), 335-337. doi: 10.1016/S0197-4580(99)00058-5 |
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1999 Journal Article Con formational homogeneity in molecular recognition by proteolytic enzymesTyndall, J. and Fairlie, D. (1999). Con formational homogeneity in molecular recognition by proteolytic enzymes. Journal of Molecular Recognition, 12 (6), 363-370. doi: 10.1002/(SICI)1099-1352(199911/12)12:63.3.CO;2-D |
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1999 Journal Article Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5aFinch, A., Wong, A. K., Paczkowski, N. J., Wadi, S. K., Craik, D. J., Fairlie, D. and Taylor, S. M. (1999). Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. Journal of Medicinal Chemistry, 42 (6), 1965-1974. doi: 10.1021/jm9806594 |
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1999 Journal Article X-ray absorption spectroscopy of cadmium phytochelatin and model systemsPickering, I. J., Prince, R. C., George, G. N., Rauser, W. E., Wickramasinghe, W. A., Watson, A. A., Dameron, C., Dance, I. G., Fairlie, D. and Salt, D. E. (1999). X-ray absorption spectroscopy of cadmium phytochelatin and model systems. Biochimica Et Biophysica Acta, 1429 (2), 351-364. doi: 10.1016/S0167-4838(98)00242-8 |
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1999 Journal Article Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate.Qiu, L., Kelso, M., Hansen, C., West, M. L., Fairlie, D. and Parsons, P. (1999). Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate.. British Journal of Cancer, 80 (8), 1252-1258. doi: 10.1038/sj.bjc.6690493 |
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1999 Journal Article Development of C5a receptor antagonistsWong, A., Taylor, S. M. and Fairlie, D. (1999). Development of C5a receptor antagonists. Investigational Drugs, 2 (7), 686-693. |
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1999 Journal Article Cyclooligomerization of Thiazole-Containing Tetrapeptides. Symmetrical Macrocycles with up to 76 Amino AcidsSokolenko, N., Abbenante, G., Scanlon, M. J., Jones, A., Gahan, L. R., Hanson, G. R. and Fairlie, D. P. (1999). Cyclooligomerization of Thiazole-Containing Tetrapeptides. Symmetrical Macrocycles with up to 76 Amino Acids. Journal of the American Chemical Society, 121 (11), 2603-2604. doi: 10.1021/ja983354n |
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1999 Journal Article Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 proteaseMartin, J. L., Begun, J., Schindeler, A., Wickramasinghe, W. A., Alewood, D., Alewood, P. F., Bergman, D. A., Brinkworth, R. I., Abbenante, G., March, D. R., Reid, R. C., Fairlie, D. P. and Armstrong, Richard A. (1999). Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38 (25), 7978-7988. doi: 10.1021/bi990174x |
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1999 Journal Article Pharmacological characterization of antagonists of the C5a receptorPaczkowski, NJ, Finch, AM, Whitmore, JB, Short, AJ, Wong, AK, Monk, PN, Cain, SA, Fairlie, DP and Taylor, SM (1999). Pharmacological characterization of antagonists of the C5a receptor. British Journal of Pharmacology, 128 (10), 1461-1466. doi: 10.1038/sj.bjp.0702938 |
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1999 Journal Article Aqueous Dissolution of Alzheimer's Disease Ab Amyloid Deposits by Biometal DepletionCherny, R. A., Legg, J. T., McLean, C. A., Fairlie, D., Huang, X., Atwood, C.S., Beyreuther, K., Tanzi, R. E., Masters, C. L. and Bush, A. (1999). Aqueous Dissolution of Alzheimer's Disease Ab Amyloid Deposits by Biometal Depletion. Journal of Biological Chemistry, 274 (33), 23223-23228. doi: 10.1074/jbc.274.33.23223 |
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1998 Journal Article Template assembled synthetic proteins (TASPS). Are template size, shape, and directionality important in formation of four-helix bundles?Wong A.K., Jacobsen M.P., Winzor D.J. and Fairlie D.P. (1998). Template assembled synthetic proteins (TASPS). Are template size, shape, and directionality important in formation of four-helix bundles?. Journal of the American Chemical Society, 120 (16), 3836-3841. doi: 10.1021/ja971951o |
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1998 Journal Article Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?Watson, AA, Fairlie, DP and Craik, DJ (1998). Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?. Biochemistry, 37 (37), 12700-12706. doi: 10.1021/bi9810757 |
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1998 Journal Article Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?Coles, M, Bicknell, W, Watson, AA, Fairlie, DP and Craik, DJ (1998). Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?. Biochemistry, 37 (31), 11064-11077. doi: 10.1021/bi972979f |
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1998 Journal Article The solution structure of a copper(II) compound of a new cyclic octapeptide by EPR spectroscopy and force field calculationsComba, P, Cusack, R, Fairlie, DP, Gahan, LR, Hanson, GR, Kazmaier, U and Ramlow, A (1998). The solution structure of a copper(II) compound of a new cyclic octapeptide by EPR spectroscopy and force field calculations. Inorganic Chemistry, 37 (26), 6721-6727. doi: 10.1021/ic9809299 |
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1998 Journal Article Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5aWong, AK, Finch, AM, Pierens, GK, Craik, DJ, Taylor, SM and Fairlie, DP (1998). Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a. Journal of Medicinal Chemistry, 41 (18), 3417-3425. doi: 10.1021/jm9800651 |
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1998 Journal Article Conformationally restricted cyclic peptides incorporating oxazoline and thiazole ring constraints.Abbenante, G., Sokolenko, N. and Fairlie, D. P. (1998). Conformationally restricted cyclic peptides incorporating oxazoline and thiazole ring constraints.. Abstracts of Papers of The American Chemical Society, 216, U382-U382. |
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1997 Journal Article Simple cis-epoxide-based inhibitors of HIV-1 proteaseAbell A.D., Hoult D.A., Bergman D.A. and Fairlie D.P. (1997). Simple cis-epoxide-based inhibitors of HIV-1 protease. Bioorganic & Medicinal Chemistry Letters, 7 (22), 2853-2856. doi: 10.1016/S0960-894X(97)10106-8 |
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1997 Journal Article Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cellsParsons, P. G., Hansen, C., Fairlie, D. P., West, M. L., Danoy, P. A. C., Sturm, R. A., Dunn, I. S., Pedley, J. and Ablett, E. M. (1997). Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells. Biochemical Pharmacology, 53 (11), 1719-1724. doi: 10.1016/S0006-2952(97)00016-6 |
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1997 Journal Article Activation of thiourea bound through sulfur to pentaammineruthenium(III): Structure and reactivityFairlie, DP, Wickramasinghe, WA, Byriel, KA and Taube, H (1997). Activation of thiourea bound through sulfur to pentaammineruthenium(III): Structure and reactivity. Inorganic Chemistry, 36 (11), 2242-2243. doi: 10.1021/ic9611397 |
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1997 Journal Article Models for arginine-metal binding. Synthesis of guanidine and urea ligands through amination and hydration of a cyanamide ligand bound to platinum(II), osmium(III), and cobalt(III)Fairlie, David P., Jackson, W. Gregory, Skelton, Brian W., Wen, Huo, White, Allan H., Wickramasinghe, Wasantha A., Woon, Tai Chin and Taube, Henry (1997). Models for arginine-metal binding. Synthesis of guanidine and urea ligands through amination and hydration of a cyanamide ligand bound to platinum(II), osmium(III), and cobalt(III). Inorganic Chemistry, 36 (6), 1020-1028. doi: 10.1021/ic961138e |
