|
2024 Conference Publication The Novel Potent Complement C3a Receptor (C3aR) Antagonist JR14a Confers Robust Neuroprotection in StrokeAhmad, Saif, Contreras, Jessica, Bhatia, Kanchan, Fairlie, David P., Waters, Michael F. and Ducruet, Andrew F. (2024). The Novel Potent Complement C3a Receptor (C3aR) Antagonist JR14a Confers Robust Neuroprotection in Stroke. American Stroke Association's 2024 International Stroke Conference, Phoenix, AZ United States, 7-9 February 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/str.55.suppl_1.tp320 |
|
2024 Journal Article Dynamic MAIT cell recovery after severe COVID-19 is transient with signs of heterogeneous functional anomaliesKammann, Tobias, Gorin, Jean-Baptiste, Parrot, Tiphaine, Gao, Yu, Ponzetta, Andrea, Emgård, Johanna, Maleki, Kimia T., Sekine, Takuya, Rivera-Ballesteros, Olga, Gredmark-Russ, Sara, Rooyackers, Olav, Skagerberg, Magdalena, Eriksson, Lars I., Norrby-Teglund, Anna, Mak, Jeffrey Y. W., Fairlie, David P., Björkström, Niklas K., Klingström, Jonas, Ljunggren, Hans-Gustaf, Aleman, Soo, Buggert, Marcus, Strålin, Kristoffer, Sandberg, Johan K. and Karolinska COVID-19 Study Group (2024). Dynamic MAIT cell recovery after severe COVID-19 is transient with signs of heterogeneous functional anomalies. The Journal of Immunology, 212 (3), 389-396. doi: 10.4049/jimmunol.2300639 |
|
2024 Journal Article Sulfated bile acid is a host-derived ligand for MAIT cellsIto, Emi, Inuki, Shinsuke, Izumi, Yoshihiro, Takahashi, Masatomo, Dambayashi, Yuki, Ciacchi, Lisa, Awad, Wael, Takeyama, Ami, Shibata, Kensuke, Mori, Shotaro, Mak, Jeffrey Y. W., Fairlie, David P., Bamba, Takeshi, Ishikawa, Eri, Nagae, Masamichi, Rossjohn, Jamie and Yamasaki, Sho (2024). Sulfated bile acid is a host-derived ligand for MAIT cells. Science Immunology, 9 (91) eade6924, eade6924. doi: 10.1126/sciimmunol.ade6924 |
|
2023 Journal Article Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cellsShah, Himani, Hill, Timothy A., Lim, Junxian and Fairlie, David P. (2023). Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells. Journal of Cell Communication and Signaling, 17 (4), 1-15. doi: 10.1007/s12079-023-00791-6 |
|
2023 Journal Article N-(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic ActivityGerokonstantis, Dimitrios Triantafyllos, Mantzourani, Christiana, Gkikas, Dimitrios, Wu, Kai-Chen, Hoang, Huy N., Triandafillidi, Ierasia, Barbayianni, Ilianna, Kanellopoulou, Paraskevi, Kokotos, Alexandros C., Moutevelis-Minakakis, Panagiota, Aidinis, Vassilis, Politis, Panagiotis K., Fairlie, David P. and Kokotos, George (2023). N-(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity. Journal of Medicinal Chemistry, 66 (20), 1-20. doi: 10.1021/acs.jmedchem.3c01422 |
|
2023 Journal Article Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011Salim, Angela A., Hussein, Waleed M., Dewapriya, Pradeep, Hoang, Huy N., Zhou, Yahao, Samarasekera, Kaumadi, Khalil, Zeinab G., Fairlie, David P. and Capon, Robert J. (2023). Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine Drugs, 21 (9) 487, 1-17. doi: 10.3390/md21090487 |
|
2023 Journal Article Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivoNelson, Adam G., Wang, Huimeng, Dewar, Phoebe M., Eddy, Eleanor M., Li, Songyi, Lim, Xin Yi, Patton, Timothy, Zhou, Yuchen, Pediongco, Troi J., Meehan, Lucy J., Meehan, Bronwyn S., Mak, Jeffrey Y. W., Fairlie, David P., Stent, Andrew W., Kjer-Nielsen, Lars, McCluskey, James, Eckle, Sidonia B. G., Corbett, Alexandra J., Souter, Michael N. T. and Chen, Zhenjun (2023). Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo. Frontiers in Immunology, 14 1109759, 1-15. doi: 10.3389/fimmu.2023.1109759 |
|
2023 Conference Publication Cigarette smoking suppresses T cell immunity in MR1-dependent mechanismAwad, Wael, Xu, Weijun, Howson, Lauren, Lim, Xin Yi, Mayall, Jemma, Fairlie, David, Hansbro, Philip, Corbett, Alexandra and Rossjohn, Jamie (2023). Cigarette smoking suppresses T cell immunity in MR1-dependent mechanism. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323094159 |
|
2023 Journal Article Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cellsAwad, Wael, Ciacchi, Lisa, McCluskey, James, Fairlie, David P. and Rossjohn, Jamie (2023). Molecular insights into metabolite antigen recognition by mucosal-associated invariant T cells. Current Opinion in Immunology, 83 102351, 1-8. doi: 10.1016/j.coi.2023.102351 |
|
2023 Journal Article Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)Goudarzi, Mohaddeseh H., Eagles, David A., Lim, Junxian, Biggs, Kimberley A., Kotze, Andrew C., Ruffell, Angela P., Fairlie, David P., King, Glenn F. and Walker, Andrew A. (2023). Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae). Biochemical Pharmacology, 213 115598, 1-11. doi: 10.1016/j.bcp.2023.115598 |
|
2023 Journal Article Wollamide cyclic hexapeptides synergize with established and new tuberculosis antibiotics in targeting Mycobacterium tuberculosisRollo, Rachel F., Mori, Giorgia, Hill, Timothy A., Hillemann, Doris, Niemann, Stefan, Homolka, Susanne, Fairlie, David P. and Blumenthal, Antje (2023). Wollamide cyclic hexapeptides synergize with established and new tuberculosis antibiotics in targeting Mycobacterium tuberculosis. Microbiology Spectrum, 11 (4). doi: 10.1128/spectrum.00465-23 |
|
2023 Journal Article Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and diseaseWang, Yizhuo, Abrol, Rishika, Mak, Jeffrey Y. W., Das Gupta, Kaustav, Ramnath, Divya, Karunakaran, Denuja, Fairlie, David P. and Sweet, Matthew J. (2023). Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease. The FEBS Journal, 290 (11), 2805-2832. doi: 10.1111/febs.16437 |
|
2023 Journal Article Effect of a protease‐activated receptor‐2 antagonist (GB88) on inflammation‐related loss of alveolar bone in periodontal diseaseFrancis, Nidhish, Sanaei, Reza, Ayodele, Babatunde A., O'Brien‐Simpson, Neil M., Fairlie, David P., Wijeyewickrema, Lakshmi C., Pike, Robert N., Mackie, Eleanor Jean and Pagel, Charles Neil (2023). Effect of a protease‐activated receptor‐2 antagonist (GB88) on inflammation‐related loss of alveolar bone in periodontal disease. Journal of Periodontal Research, 58 (3), 544-552. doi: 10.1111/jre.13120 |
|
2023 Journal Article Hydrolases in GtoPdb v.2023.1Alexander, Stephen P.H., Doherty, Patrick, Fairlie, David, Fowler, Christopher J., Overall, Christopher M., Rawlings, Neil, Southan, Christopher and Turner, Anthony J. (2023). Hydrolases in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE, 2023 (1), 1-10. doi: 10.2218/gtopdb/f799/2023.1 |
|
2023 Journal Article Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activationAshley, Caroline L., McSharry, Brian P., McWilliam, Hamish E. G., Stanton, Richard J., Fielding, Ceri A., Mathias, Rommel A., Fairlie, David P., McCluskey, James, Villadangos, Jose A., Rossjohn, Jamie, Abendroth, Allison and Slobedman, Barry (2023). Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation. Frontiers in Immunology, 14 1107497, 1-13. doi: 10.3389/fimmu.2023.1107497 |
|
2023 Journal Article HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophagesDas Gupta, Kaustav, Ramnath, Divya, von Pein, Jessica B., Curson, James E. B., Wang, Yizhuo, Abrol, Rishika, Kakkanat, Asha, Moradi, Shayli Varasteh, Gunther, Kimberley S., Murthy, Ambika M. V., Stocks, Claudia J., Kapetanovic, Ronan, Reid, Robert C., Iyer, Abishek, Ilka, Zoe C., Nauseef, William M., Plan, Manuel, Luo, Lin, Stow, Jennifer L., Schroder, Kate, Karunakaran, Denuja, Alexandrov, Kirill, Shakespear, Melanie R., Schembri, Mark A., Fairlie, David P. and Sweet, Matthew J. (2023). HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences, 120 (4) e2212813120, 1-12. doi: 10.1073/pnas.2212813120 |
|
2023 Journal Article Ras related protein Rab5a regulates complement C5a receptor trafficking, chemotaxis and chemokine secretion in human macrophagesWu, Kai-Chen, Condon, Nicholas D., Hill, Timothy A., Reid, Robert C., Fairlie, David and Lim, Junxian (2023). Ras related protein Rab5a regulates complement C5a receptor trafficking, chemotaxis and chemokine secretion in human macrophages. Journal of Innate Immunity, 15 (1), 468-484. doi: 10.1159/000530012 |
|
2022 Journal Article Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1Wang, Carl J.H., Awad, Wael, Liu, Ligong, Mak, Jeffrey Y.W., Veerapen, Natacha, Illing, Patricia T., Purcell, Anthony W., Eckle, Sidonia B.G., McCluskey, James, Besra, Gurdyal S., Fairlie, David P., Rossjohn, Jamie and Le Nours, Jérôme (2022). Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1. Journal of Biological Chemistry, 298 (12) 102714, 1-12. doi: 10.1016/j.jbc.2022.102714 |
|
2022 Journal Article Helical structure in cyclic peptides: effect of N-methyl amides versus estersWu, Chongyang, Hoang, Huy N., Hill, Timothy A., Lim, Junxian, Kok, W. Mei, Akondi, Kalyani, Liu, Ligong and Fairlie, David P. (2022). Helical structure in cyclic peptides: effect of N-methyl amides versus esters. Chemical Communications, 58 (89), 12475-12478. doi: 10.1039/d2cc05092g |
|
2022 Journal Article A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cellsLim, Hui Jing, Wubben, Jacinta M., Garcia, Cristian Pinero, Cruz-Gomez, Sebastian, Deng, Jieru, Mak, Jeffrey Y.W., Hachani, Abderrahman, Anderson, Regan J., Painter, Gavin F., Goyette, Jesse, Amarasinghe, Shanika L., Ritchie, Matthew E., Roquilly, Antoine, Fairlie, David P., Gaus, Katharina, Rossjohn, Jamie, Villadangos, Jose A. and McWilliam, Hamish E.G. (2022). A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells. Journal of Cell Biology, 221 (12) e202110125. doi: 10.1083/jcb.202110125 |
