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2015

Journal Article

No full admission for tau to the exclusive prion club yet

Polanco, Juan Carlos and Götz, Jürgen (2015). No full admission for tau to the exclusive prion club yet. EMBO Journal, 34 (24), 2990-2992. doi: 10.15252/embj.201593311

No full admission for tau to the exclusive prion club yet

2015

Journal Article

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

Grimm, Amandine, Biliouris, Emily E., Lang, Undine E., Gotz, Jurgen, Mensah-Nyagan, Ayikoe Guy and Eckert, Anne (2015). Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein. Cellular and Molecular Life Sciences, 73 (1), 201-215. doi: 10.1007/s00018-015-1988-x

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

2015

Journal Article

FTD and ALS—translating mouse studies into clinical trials

Ittner, Lars M., Halliday, Glenda M., Kril, Jillian J., Götz, Jürgen, Hodges, John R. and Kiernan, Matthew C. (2015). FTD and ALS—translating mouse studies into clinical trials. Nature Reviews Neurology, 11 (6), 360-366. doi: 10.1038/nrneurol.2015.65

FTD and ALS—translating mouse studies into clinical trials

2015

Journal Article

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

Xia, Di, Li, Chuanzhou and Gotz, Jurgen (2015). Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852 (5), 913-924. doi: 10.1016/j.bbadis.2014.12.017

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

2015

Journal Article

Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease

Cummins, Nadia and Götz, Jurgen (2015). Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease. Australian Biochemist, 46 (1), 4-7.

Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease

2015

Journal Article

Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model

Leinenga, Gerhard and Götz, Jürgen (2015). Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model. Science Translational Medicine, 7 (278) 278ra33, 278ra33.1-278ra33.12. doi: 10.1126/scitranslmed.aaa2512

Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model

2015

Journal Article

Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress

Chew, Yee Lian, Gotz, Jurgen and Nicholas, Hannah R. (2015). Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress. Aging Cell, 14 (1), 148-151. doi: 10.1111/acel.12285

Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress

2015

Journal Article

What we can learn from animal models about cerebral multi-morbidity

Baker, Sian and Gotz, Jurgen (2015). What we can learn from animal models about cerebral multi-morbidity. Alzheimer's Research and Therapy, 7 (11) 11, 11. doi: 10.1186/s13195-015-0097-2

What we can learn from animal models about cerebral multi-morbidity

2015

Journal Article

Connecting the dots between tau dysfunction and neurodegeneration

Frost, Bess, Gotz, Jurgen and Feany, Mel B. (2015). Connecting the dots between tau dysfunction and neurodegeneration. Trends in Cell Biology, 25 (1), 46-53. doi: 10.1016/j.tcb.2014.07.005

Connecting the dots between tau dysfunction and neurodegeneration

2014

Journal Article

Tau aggregation and its interplay with amyloid-β

Nisbet, Rebecca M., Polanco, Juan-Carlos, Ittner, Lars M. and Gotz, Jurgen (2014). Tau aggregation and its interplay with amyloid-β. Acta Neuropathologica, 129 (2), 207-220. doi: 10.1007/s00401-014-1371-2

Tau aggregation and its interplay with amyloid-β

2014

Journal Article

Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis

Kohler, Christoph, Dinekov, Maja and Gotz, Jürgen (2014). Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis. Neurobiology of Disease, 71, 169-179. doi: 10.1016/j.nbd.2014.07.006

Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis

2014

Journal Article

Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans

Ullrich, Milena, Liang, Vanessa, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Lam, Hong, Berber, Slavica, Kassiou, Michael, Nicholas, Hannah R. and Goetz, Juergen (2014). Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 9 (9), 2237-2255. doi: 10.1038/nprot.2014.150

Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans

2014

Journal Article

Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

Liang, Vanessa, Ullrich, Milena, Lam, Hong, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Kassiou, Michael, Gotz, Jürgen and Nicholas, Hannah R. (2014). Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome. Cellular and Molecular Life Sciences, 71 (17), 3339-3361. doi: 10.1007/s00018-014-1558-7

Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

2014

Journal Article

Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice

Ittner, Arne, Bertz, Josefine, Suh, Lisa S., Stevens, Claire H., Gotz, Jurgen and Ittner, Lars M. (2014). Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. Journal of Neurochemistry, 132 (1), 1-11. doi: 10.1111/jnc.12821

Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice

2014

Journal Article

Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous

Chew, Yee Lian, Fan, Xiaochen, Gotz, Jurgen and Nicholas, Hannah R. (2014). Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous. Scientific Reports, 4 (1) 5185, 5185. doi: 10.1038/srep05185

Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous

2014

Journal Article

Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn

Xia, Di and Gotz, Jurgen (2014). Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn. Frontiers in Molecular Neuroscience, 7 (MAY) 40, 1-11. doi: 10.3389/fnmol.2014.00040

Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn

2014

Journal Article

The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells

Chen, JinYan, Sun, MengRu, Wang, XingHua, Lu, Jing, Wei, Yan, Tan, Yan, Liu, Ying, Gotz J., He, RongQiao and Hua, Qian (2014). The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells. Science China Life Sciences, 57 (4), 412-421. doi: 10.1007/s11427-014-4643-0

The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells

2014

Journal Article

Visualizing the microtubule-associated protein tau in the nucleus

Lu, Jing, Li, Ting, He, RongQiao, Bartlett, Perry F. and Gotz, Jürgen (2014). Visualizing the microtubule-associated protein tau in the nucleus. Science China Life Sciences, 57 (4), 422-431. doi: 10.1007/s11427-014-4635-0

Visualizing the microtubule-associated protein tau in the nucleus

2013

Journal Article

Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus

Liu, Chang and Goetz, Juergen (2013). Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus. PloS One, 8 (12) e84849, e84849. doi: 10.1371/journal.pone.0084849

Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus

2013

Journal Article

March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

Eckert, Anne, Nisbet, Rebecca, Grimm, Amandine and Götz, Jürgen (2013). March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease. Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease, 1842 (8), 1258-1266. doi: 10.1016/j.bbadis.2013.08.013

March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease