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2024 Journal Article Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastomaLogan, Amy, Howard, Christopher B., Huda, Pie, Kimpton, Kathleen, Ma, Zerong, Thurecht, Kristofer J., McCarroll, Joshua A., Moles, Ernest and Kavallaris, Maria (2024). Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma. Journal of Controlled Release, 367, 806-820. doi: 10.1016/j.jconrel.2024.02.007 |
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2023 Journal Article Integration of yeast episomal/integrative plasmid causes genotypic and phenotypic diversity and improved sesquiterpene production in metabolically engineered Saccharomyces cerevisiaePeng, Bingyin, Weintraub, Sarah J., Lu, Zeyu, Evans, Samuel, Shen, Qianyi, McDonnell, Liam, Plan, Manuel, Collier, Thomas, Cheah, Li Chen, Ji, Lei, Howard, Christopher B., Anderson, Will, Trau, Matt, Dumsday, Geoff, Bredeweg, Erin L., Young, Eric M., Speight, Robert and Vickers, Claudia E. (2023). Integration of yeast episomal/integrative plasmid causes genotypic and phenotypic diversity and improved sesquiterpene production in metabolically engineered Saccharomyces cerevisiae. ACS Synthetic Biology, 13 (1), 141-156. doi: 10.1021/acssynbio.3c00363 |
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2023 Journal Article An immunomodulating peptide with potential to suppress tumour growth and autoimmunityAgrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley and Gallagher, Laura (2023). An immunomodulating peptide with potential to suppress tumour growth and autoimmunity. Scientific Reports, 13 (1) 19741, 19741. doi: 10.1038/s41598-023-47229-y |
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2023 Journal Article Click‐on antibody fragments for customisable targeted nanomedicines – site‐specific tetrazine and azide functionalisation through non‐canonical amino acid incorporationHuda, Pie, Humphries, James, Fletcher, Nicholas L., Howard, Christopher B., Thurecht, Kristofer J. and Bell, Craig A. (2023). Click‐on antibody fragments for customisable targeted nanomedicines – site‐specific tetrazine and azide functionalisation through non‐canonical amino acid incorporation. Chemistry–Methods, 4 (2) e202300036. doi: 10.1002/cmtd.202300036 |
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2023 Journal Article Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiaeLu, Zeyu, Shen, Qianyi, Liu, Lian, Talbo, Gert, Speight, Robert, Trau, Matt, Dumsday, Geoff, Howard, Christopher B., Vickers, Claudia E. and Peng, Bingyin (2023). Profiling proteomics responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae. Engineering Microbiology, 3 (3) 100079, 100079. doi: 10.1016/j.engmic.2023.100079 |
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2023 Journal Article An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damageAgrez, Michael, Rybchyn, Mark Stephen, De Silva, Warusavithana Gunawardena Manori, Mason, Rebecca Sara, Chandler, Christopher, Piva, Terrence J., Thurecht, Kristofer, Fletcher, Nicholas, Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew, Gooding, Hayley and Gallagher, Laura (2023). An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage. Scientific Reports, 13 (1) 11702, 1-19. doi: 10.1038/s41598-023-38890-4 |
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2023 Conference Publication Dox- loaded mpeg nanoparticles as a promising treatment in a humanized mouse model for breast cancer bone metastasisFrankenbach, Tina, Landgraf, Marietta, Fletcher, Nicholas, Howard, Christopher, Ravichandran, Akhilandeshwari, Akhter, Dewan, Shafiee, Abbas, Holzapfel, Boris M., Thurecht, Kristofer, McGovern, Jacqui and Hutmacher, Dietmar W. (2023). Dox- loaded mpeg nanoparticles as a promising treatment in a humanized mouse model for breast cancer bone metastasis. Tissue Engineering and Regenerative Medicine International Society (TERMIS), Krakow, Poland, 28 June - 1 July 2022. New Rochelle, NY United States: Mary Ann Liebert. |
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2023 Journal Article Pharmacokinetics and Biodistribution of Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in GlioblastomaGhosh, Saikat, Fletcher, Nicholas L., Huda, Pie, Houston, Zachary H., Howard, Christopher B., Lund, Maria E., Lu, Yanling, Campbell, Douglas H., Walsh, Bradley J. and Thurecht, Kristofer J. (2023). Pharmacokinetics and Biodistribution of Zr-Miltuximab and Its Antibody Fragments as Glypican-1 Targeting Immuno-PET Agents in Glioblastoma. Molecular pharmaceutics, 20 (3), 1549-1563. doi: 10.1021/acs.molpharmaceut.2c00760 |
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2022 Journal Article Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxesFarokhinejad, Fahimeh, Li, Junrong, Hugo, Leon E., Howard, Christopher B., Wuethrich, Alain and Trau, Matt (2022). Detection of Dengue Virus 2 with single infected mosquito resolution using yeast affinity bionanofragments and plasmonic SERS nanoboxes. Analytical Chemistry, 94 (41), 14177-14184. doi: 10.1021/acs.analchem.2c02012 |
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2022 Journal Article PD-L1-targeted co-delivery of two chemotherapeutics for efficient suppression of skin cancer growthMovahedi, Fatemeh, Liu, Jie, Sun, Bing, Cao, Pei, Sun, Luyao, Howard, Christopher, Gu, Wenyi and Xu, Zhi Ping (2022). PD-L1-targeted co-delivery of two chemotherapeutics for efficient suppression of skin cancer growth. Pharmaceutics, 14 (7) 1488, 1488. doi: 10.3390/pharmaceutics14071488 |
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2022 Journal Article A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responsesAgrez, Michael, Rzepecka, Justyna, Turner, Darryl, Knox, Gavin, Chandler, Christopher, Howard, Christopher B., Fletcher, Nicholas, Thurecht, Kristofer, Parker, Stephen, Gooding, Hayley and Gallagher, Laura (2022). A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses. Scientific Reports, 12 (1) 11185, 11185. doi: 10.1038/s41598-022-15455-5 |
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2022 Journal Article Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted deliveryGao, Zhiliang, Li, Xiaoyu, Zhao, Kaijie, Geng, Huimin, Zhang, Peiyu, Ju, Yi, Huda, Pie, Howard, Christopher B, Thurecht, Kristofer J, Ashokkumar, Muthupandian, Hao, Jingcheng and Cui, Jiwei (2022). Confined microemulsion sono-polymerization of poly(ethylene glycol) nanoparticles for targeted delivery. Chemical Communications, 58 (56), 7777-7780. doi: 10.1039/d2cc01874h |
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2022 Journal Article An in vivo gene amplification system for high level expression in Saccharomyces cerevisiaePeng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae. Nature Communications, 13 (1) 2895, 2895. doi: 10.1038/s41467-022-30529-8 |
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2022 Conference Publication Immuno-PET agents for targeting glioblastomaGhosh, S., Huda, P., Fletcher, N., Howard, C., Lu, Y., Campbell, D., Walsh, B. and Thurecht, K. (2022). Immuno-PET agents for targeting glioblastoma. Australian and New Zealand Society of Nuclear Medicine (ANZSNM) 52nd ASM, Brisbane, QLD, Australia, 13–15 May 2022. Richmond, VIC, Australia: John Wiley & Sons. |
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2022 Journal Article Antibody-based formats to target glioblastoma: overcoming barriers to protein drug deliveryGhosh, Saikat, Huda, Pie, Fletcher, Nicholas L., Howard, Christopher B., Walsh, Bradley, Campbell, Douglas, Pinkham, Mark B. and Thurecht, Kristofer J. (2022). Antibody-based formats to target glioblastoma: overcoming barriers to protein drug delivery. Molecular Pharmaceutics, 19 (5), 1233-1247. doi: 10.1021/acs.molpharmaceut.1c00996 |
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2022 Journal Article Recent advances in the production of recombinant factor IX: bioprocessing and cell engineeringBeauglehole, Aiden C, Roche Recinos, Dinora, Pegg, Cassandra L, Lee, Yih Yean, Turnbull, Victor, Herrmann, Susann, Marcellin, Esteban, Howard, Christopher B and Schulz, Benjamin L (2022). Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering. Critical Reviews in Biotechnology, 43 (3), 1-19. doi: 10.1080/07388551.2022.2036691 |
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2022 Journal Article Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruptionJanowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416 |
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2022 Journal Article Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics NeogenesisKenny, Sophie E., Antaw, Fiach, Locke, Warwick J., Howard, Christopher B., Korbie, Darren and Trau, Matt (2022). Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis. Life, 12 (3) 363, 1-24. doi: 10.3390/life12030363 |
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2022 Journal Article Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiaePeng, Bingyin, Bandari, Naga Chandra, Lu, Zeyu, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff and Vickers, Claudia E. (2022). Engineering eukaryote-like regulatory circuits to expand artificial control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology, 5 (1) 135, 135. doi: 10.1038/s42003-022-03070-z |
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2021 Journal Article Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detectionFarokhinejad, Fahimeh, Lane, Rebecca E., Lobb, Richard J., Edwardraja, Selvakumar, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2021). Generation of nanoyeast single-chain variable fragments as high-avidity biomaterials for dengue virus detection. ACS Biomaterials Science and Engineering, 7 (12) acsbiomaterials.1c01001, 5850-5860. doi: 10.1021/acsbiomaterials.1c01001 |
