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2018 Journal Article Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutantPham, Huong Thi, Nhiep, Nguyen Thi Hanh, Vu, Thu Ngoc Minh, Huynh, TuAnh Ngoc, Zhu, Yan, Huynh, Anh Le Diep, Chakrabortti, Alolika, Marcellin, Esteban, Lo, Raquel, Howard, Christopher B., Bansal, Nidhi, Woodward, Joshua J., Liang, Zhao-Xun and Turner, Mark S. (2018). Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant. PLOS Genetics, 14 (8) e1007574, e1007574. doi: 10.1371/journal.pgen.1007574 |
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2018 Journal Article Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approachFontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288 |
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2018 Journal Article Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligandsTang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j |
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2018 Journal Article Bispecific antibody-functionalized upconversion nanoprobeHe, Hao, Howard, Christopher B., Chen, Yinghui, Wen, Shihui, Lin, Gungun, Zhou, Jiajia, Thurecht, Kristofer J. and Jin, Dayong (2018). Bispecific antibody-functionalized upconversion nanoprobe. Analytical Chemistry, 90 (5), 3024-3029. doi: 10.1021/acs.analchem.7b05341 |
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2018 Journal Article Recent advances in the generation of antibody-nanomaterial conjugatesSivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607 |
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2017 Journal Article Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft modelsAlfaleh, Mohamed A., Howard, Christopher B., Sedliarou, Ilya, Jones, Martina L., Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H., de Bakker, Christopher J., Milne, Michael R., Rumballe, Bree A., MacDiarmid, Jennifer A., Brahmbhatt, Himanshu and Mahler, Stephen M. (2017). Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models. Plos One, 12 (10) e0186137, e0186137. doi: 10.1371/journal.pone.0186137 |
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2017 Journal Article Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensingWuethrich, Alain, Howard, Christopher B. and Trau, Matt (2017). Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing. Microchemical Journal, 137, 231-237. doi: 10.1016/j.microc.2017.10.012 |
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2017 Journal Article Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsionsTayeb, Hossam H, Piantavigna, Stefania, Howard, Christopher B, Nouwens, Amanda, Mahler, Stephen M, Middelberg, Anton P J, He, Lizhong, Holt, Stephen A and Sainsbury, Frank (2017). Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions. Soft matter, 13 (43), 7953-7961. doi: 10.1039/c7sm01614j |
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2017 Journal Article Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based PanningAlfaleh, Mohamed A., Jones, Martina L., Howard, Christopher B. and Mahler, Stephen M. (2017). Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning. Antibodies, 6 (3) 10, 1-19. doi: 10.3390/antib6030010 |
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2016 Journal Article Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10Alsultan, Abdulkarim M., Chin, David Y., Howard, Christopher B., de Bakker, Christopher J., Jones, Martina L. and Mahler, Stephen M. (2016). Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10. Scientific Reports, 5 (37348) 37348, 37348. doi: 10.1038/srep37348 |
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2016 Journal Article Biosimilars approved for treatment of inflammatory rheumatological diseasesMahler, Stephen M., Wardiana, Andri, Jones, Martina L., De Bakker, Christopher J., Graham, Garry G. and Howard, Christopher B. (2016). Biosimilars approved for treatment of inflammatory rheumatological diseases. International Journal of Rheumatic Diseases, 19 (11), 1043-1048. doi: 10.1111/1756-185X.13037 |
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2016 Journal Article Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific AntibodiesHoward, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263 |
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2016 Journal Article Targeting membrane proteins for antibody discovery using phage displayJones, Martina L., Alfaleh, Mohamed A., Kumble, Sumukh, Zhang, Shuo, Osborne, Geoffrey W., Yeh, Michael, Arora, Neetika, Hou, Jeff Jia Cheng, Howard, Christopher B., Chin, David Y. and Mahler, Stephen M. (2016). Targeting membrane proteins for antibody discovery using phage display. Scientific Reports, 6 (1) 26240, 26240. doi: 10.1038/srep26240 |
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2016 Journal Article Biosensing made easy with PEG-targeted bi-specific antibodiesRaftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A |
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2015 Journal Article Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cellsTang, Jie, Li, Li, Howard, Christopher B., Mahler, Stephen M., Huang, Leaf and Xu, Zhi Ping (2015). Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells. Journal of Materials Chemistry B, 3 (33), 6805-6812. doi: 10.1039/c5tb00912j |
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2015 Journal Article Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory diseaseNaylor, Dean J., Hunt, Ben, Guidolin, Angelo, Hey, Allan W., Bastiras, Stan, de Bakker, Christopher J., Chin, David Y., Marquis, Christopher P., Lambert, Daniel, Howard, Christopher B., Dobbin, Caroline A. and Mahler, Stephen M. (2015). Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory disease. Process Biochemistry, 50 (10) 10466, 1669-1679. doi: 10.1016/j.procbio.2015.06.022 |
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2014 Journal Article Nanocell targeting using engineered bispecific antibodies.Taylor, Karin, Howard, Christopher B., Jones, Martina L., Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P. and Mahler, Stephen M. (2014). Nanocell targeting using engineered bispecific antibodies.. mAbs, 7 (1), 53-65. doi: 10.4161/19420862.2014.985952 |
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2014 Journal Article Development of a protein nanoparticle platform for targeting EGFR expressing cancer cellsBuecheler, Jakob W., Howard, Christopher B., de Bakker, Christopher J., Goodall, Stephen, Jones, Martina L, Win, Thinzar, Peng, Tao, Tan, Cher Heng, Chopra, Akhil, Mahler, Stephen M and Lim, Sierin (2014). Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells. Journal of Chemical Technology and Biotechnology, 90 (7), 1230-1236. doi: 10.1002/jctb.4545 |
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2014 Journal Article An EGFR targeting nanoparticle self assembled from a thermoresponsive polymerGoodall, Stephen, Howard, Christopher B., Jones, Martina L., Munro,Trent, Jia, Zhongfan, Monteiro, Michael J and Mahler, Stephen (2014). An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer. Journal of Chemical Technology and Biotechnology, 90 (7), 1222-1229. doi: 10.1002/jctb.4509 |
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2012 Journal Article Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATPMo, Jinyao, Boyle, Joseph P., Howard, Christopher B., Monie, Tom P., Davis, Beckley K. and Duncan, Joseph A. (2012). Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP. Journal of Biological Chemistry, 287 (27), 23057-23067. doi: 10.1074/jbc.M112.344283 |
