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2023 Journal Article Mapping the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironmentJhaveri, Niyati, Ben Cheikh, Bassem, Nikulina, Nadezhda, Ma, Ning, Klymyshyn, Dmytro, DeRosa, James, Mihani, Ritu, Pratapa, Aditya, Kassim, Yasmin, Bommakanti, Sidharth, Shang, Olive, Berry, Shannon, Ihley, Nicholas, McLane, Michael, He, Yan, Zheng, Yi, Monkman, James, Cooper, Caroline, O'Byrne, Ken, Anand, Bhaskar, Prater, Michael, Basu, Subham, Hughes, Brett G. M., Kulasinghe, Arutha and Braubach, Oliver (2023). Mapping the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironment. GEN Biotechnology, 2 (5), 418-434. doi: 10.1089/genbio.2023.0029 |
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2023 Journal Article The seductive allure of spatial biology: accelerating new discoveries in the life sciencesKulasinghe, Arutha, Wood, Fiona and Belz, Gabrielle (2023). The seductive allure of spatial biology: accelerating new discoveries in the life sciences. Immunology and Cell Biology, 101 (9), 798-804. doi: 10.1111/imcb.12669 |
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2023 Journal Article Advances in novel strategies for isolation, characterization, and analysis of CTCs and ctDNAYaghoubi Naei, Vahid, Bordhan, Pritam, Mirakhorli, Fatemeh, Khorrami, Motahare, Shrestha, Jesus, Nazari, Hojjatollah, Kulasinghe, Arutha and Ebrahimi Warkiani, Majid (2023). Advances in novel strategies for isolation, characterization, and analysis of CTCs and ctDNA. Therapeutic Advances in Medical Oncology, 15 17588359231192401, 1-40. doi: 10.1177/17588359231192401 |
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2023 Journal Article A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissuesTan, Xiao, Grice, Laura F., Tran, Minh, Mulay, Onkar, Monkman, James, Blick, Tony, Vo, Tuan, Almeida, Ana Clara, da Silva Motta, Jarbas, Fernandes de Moura, Karen, Machado‐Souza, Cleber, Souza‐Fonseca‐Guimaraes, Paulo, Baena, Cristina Pellegrino, de Noronha, Lucia, Guimaraes, Fernanda Simoes Fortes, Luu, Hung N., Drennon, Tingsheng, Williams, Stephen, Stern, Jacob, Uytingco, Cedric, Pan, Liuliu, Nam, Andy, Cooper, Caroline, Short, Kirsty, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Kulasinghe, Arutha and Nguyen, Quan (2023). A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues. Immunology, 170 (3), 401-418. doi: 10.1111/imm.13679 |
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2023 Journal Article Multi‐omic and spatial dissection of immunotherapy response groups in non‐small cell lung cancerMonkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Matigian, Nicholas, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Mueller, Scott N., Adams, Mark N., O'Byrne, Ken and Kulasinghe, Arutha (2023). Multi‐omic and spatial dissection of immunotherapy response groups in non‐small cell lung cancer. Immunology, 169 (4), 487-502. doi: 10.1111/imm.13646 |
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2023 Journal Article Mapping immunotherapy sensitivity with multiomic approachesKulasinghe, Arutha (2023). Mapping immunotherapy sensitivity with multiomic approaches. Immuno Oncology Insights, 4 (6), 235-237. doi: 10.18609/ioi.2023.031 |
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2023 Journal Article Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoringAhmed, Mostak, Wuethrich, Alain, Constantin, Nicolas, Shanmugasundaram, Karthik Balaji, Mainwaring, Paul, Kulasinghe, Arutha, O’Leary, Connor, O’Byrne, Ken, Sina, Abu Ali Ibn, Carrascosa, Laura G. and Trau, Matt (2023). Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoring. Analytical Chemistry, 95 (22), 8522-8532. doi: 10.1021/acs.analchem.3c00519 |
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2023 Journal Article Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapySadeghirad, Habib, Liu, Ning, Monkman, James, Ma, Ning, Cheikh, Bassem Ben, Jhaveri, Niyati, Tan, Chin Wee, Warkiani, Majid Ebrahimi, Adams, Mark N., Nguyen, Quan, Ladwa, Rahul, Braubach, Oliver, O’Byrne, Ken, Davis, Melissa, Hughes, Brett G. M. and Kulasinghe, Arutha (2023). Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy. Frontiers in Immunology, 14 1135489, 1-16. doi: 10.3389/fimmu.2023.1135489 |
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2023 Journal Article Blood transcriptome responses in patients correlate with severity of COVID-19 diseaseWang, Ya, Schughart, Klaus, Pelaia, Tiana Maria, Chew, Tracy, Kim, Karan, Karvunidis, Thomas, Knippenberg, Ben, Teoh, Sally, Phu, Amy L., Short, Kirsty R., Iredell, Jonathan, Thevarajan, Irani, Audsley, Jennifer, Macdonald, Stephen, Burcham, Jonathon, McLean, Anthony, Tang, Benjamin, Shojaei, Maryam, PREDICT-19 consortium, Kulasinghe, Arutha and Carney, Meagan E. (2023). Blood transcriptome responses in patients correlate with severity of COVID-19 disease. Frontiers in Immunology, 13 1043219, 1-18. doi: 10.3389/fimmu.2022.1043219 |
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2023 Journal Article IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational studyShojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438 |
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2023 Journal Article Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damageKulasinghe, Arutha, Liu, Ning, Tan, Chin Wee, Monkman, James, Sinclair, Jane E., Bhuva, Dharmesh D., Godbolt, David, Pan, Liuliu, Nam, Andy, Sadeghirad, Habib, Sato, Kei, Bassi, Gianluigi Li, O'Byrne, Ken, Hartmann, Camila, Miggiolaro, Anna Flavia Ribeiro dos Santos, Marques, Gustavo Lenci, Moura, Lidia Zytynski, Richard, Derek, Adams, Mark, Noronha, Lucia de, Baena, Cristina Pellegrino, Suen, Jacky Y., Arora, Rakesh, Belz, Gabrielle T., Short, Kirsty R., Davis, Melissa J., Souza‐Fonseca Guimaraes, Fernando and Fraser, John F. (2023). Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damage. Immunology, 168 (3), 403-419. doi: 10.1111/imm.13577 |
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2022 Journal Article Single-cell analysis of circulating tumour cells: enabling technologies and clinical applicationsRadfar, Payar, Aboulkheyr Es, Hamidreza, Salomon, Rob, Kulasinghe, Arutha, Ramalingam, Naveen, Sarafraz-Yazdi, Ehsan, Thiery, Jean Paul and Warkiani, Majid Ebrahimi (2022). Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications. Trends in Biotechnology, 40 (9), 1041-1060. doi: 10.1016/j.tibtech.2022.02.004 |
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2022 Journal Article Immunotherapeutic targets in non‐small cell lung cancerSadeghi Rad, Habib, Bahrami, Tayyeb, Layeghi, Sepideh Mehrpour, Yousefi, Hassan, Rezaei, Meysam, Hosseini‐Fard, Seyed Reza, Radfar, Payar, Warkiani, Majid Ebrahimi, O’Byrne, Ken and Kulasinghe, Arutha (2022). Immunotherapeutic targets in non‐small cell lung cancer. Immunology, 168 (2), 1-17. doi: 10.1111/imm.13562 |
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2022 Journal Article A robust experimental and computational analysis framework at multiple resolutions, modalities and coveragesTran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873 |
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2022 Journal Article Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell CarcinomasSadeghirad, Habib, Monkman, James, Mehdi, Ahmed M., Ladwa, Rahul, O’Byrne, Ken, Hughes, Brett G. M. and Kulasinghe, Arutha (2022). Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas. Frontiers in Immunology, 13 895513, 1-11. doi: 10.3389/fimmu.2022.895513 |
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2022 Journal Article Immune checkpoint inhibitors in cancer therapyShiravand, Yavar, Khodadadi, Faezeh, Kashani, Seyyed Mohammad Amin, Hosseini-Fard, Seyed Reza, Hosseini, Shadi, Sadeghirad, Habib, Ladwa, Rahul, O’Byrne, Ken and Kulasinghe, Arutha (2022). Immune checkpoint inhibitors in cancer therapy. Current Oncology, 29 (5), 3044-3060. doi: 10.3390/curroncol29050247 |
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2022 Journal Article Clinical applications of circulating tumour cells and circulating tumour dna in non-small cell lung cancer—an updateKapeleris, Joanna, Ebrahimi Warkiani, Majid, Kulasinghe, Arutha, Vela, Ian, Kenny, Liz, Ladwa, Rahul, O’Byrne, Kenneth and Punyadeera, Chamindie (2022). Clinical applications of circulating tumour cells and circulating tumour dna in non-small cell lung cancer—an update. Frontiers in Oncology, 12 859152, 1-18. doi: 10.3389/fonc.2022.859152 |
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2022 Journal Article The role of circulating biomarkers in lung cancerHerath, Sayuri, Sadeghi Rad, Habib, Radfar, Payar, Ladwa, Rahul, Warkiani, Majid, O’Byrne, Ken and Kulasinghe, Arutha (2022). The role of circulating biomarkers in lung cancer. Frontiers in Oncology, 11 801269, 1-13. doi: 10.3389/fonc.2021.801269 |
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2022 Journal Article Spatial profiling identifies prognostic features of response to adjuvant therapy in Triple Negative Breast Cancer (TNBC)Kulasinghe, Arutha, Monkman, James, Shah, Esha T., Matigian, Nicholas, Adams, Mark N. and O’Byrne, Ken (2022). Spatial profiling identifies prognostic features of response to adjuvant therapy in Triple Negative Breast Cancer (TNBC). Frontiers in Oncology, 11 798296, 798296. doi: 10.3389/fonc.2021.798296 |
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2022 Journal Article Corrigendum: The effects of COVID-19 on the placenta during pregnancyRad, Habib Sadeghi, Röhl, Joan, Stylianou, Nataly, Allenby, Mark C., Bazaz, Sajad Razavi, Warkiani, Majid E., Guimaraes, Fernando S F, Clifton, Vicki L. and Kulasinghe, Arutha (2022). Corrigendum: The effects of COVID-19 on the placenta during pregnancy. Frontiers in immunology, 13 998406, 998406. doi: 10.3389/fimmu.2022.998406 |