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2025 Journal Article Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analysesPanagiotaropoulou, Georgia, Hellberg, Kajsa-Lotta Georgii, Coleman, Jonathan R. I., Seok, Darsol, Kalman, Janos, Mitchell, Philip B., Schofield, Peter R., Forstner, Andreas J., Bauer, Michael, Scott, Laura J., Pato, Carlos N., Pato, Michele T., Li, Qingqin S., Kirov, George, Landén, Mikael, Jonsson, Lina, Müller-Myhsok, Bertram, Smoller, Jordan W., Binder, Elisabeth B., Brückl, Tanja M., Czamara, Darina, Van Der Auwera, Sandra, Grabe, Hans J., Homuth, Georg, Schmidt, Carsten O., Potash, James B., Depaulo, J. Raymond, Goes, Fernando S., Mackinnon, Dean F. ... Olde Loohuis, Loes (2025). Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses. British Journal of Psychiatry, 226 (2), 1-12. doi: 10.1192/bjp.2024.125 |
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2025 Journal Article Genomics yields biological and phenotypic insights into bipolar disorderO’Connell, Kevin S., Koromina, Maria, van der Veen, Tracey, Boltz, Toni, David, Friederike S., Yang, Jessica Mei Kay, Lin, Keng-Han, Wang, Xin, Coleman, Jonathan R. I., Mitchell, Brittany L., McGrouther, Caroline C., Rangan, Aaditya V., Lind, Penelope A., Koch, Elise, Harder, Arvid, Parker, Nadine, Bendl, Jaroslav, Adorjan, Kristina, Agerbo, Esben, Albani, Diego, Alemany, Silvia, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F. M., Antoniou, Anastasia, Ask, Helga, Bass, Nicholas, Bauer, Michael, Beins, Eva C. ... Andreassen, Ole A. (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639 (8056), 968-975. doi: 10.1038/s41586-024-08468-9 |
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2025 Journal Article Investigating the Relationship Between Maternal Smoking During Pregnancy and Offspring Handedness: Extending the Proxy Gene-by-Environment Mendelian Randomization Study Design to Include Polygenic Risk ScoresCrick, Daisy C. P., Medland, Sarah E., Smith, George Davey and Evans, David M. (2025). Investigating the Relationship Between Maternal Smoking During Pregnancy and Offspring Handedness: Extending the Proxy Gene-by-Environment Mendelian Randomization Study Design to Include Polygenic Risk Scores. Behavior Genetics, 55 (4), 1-13. doi: 10.1007/s10519-025-10226-0 |
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2024 Journal Article Accelerating heritability, genetic correlation, and genome‐wide association imaging genetic analyses in complex pedigreesDonohue, Brian, Gao, Si, Nichols, Thomas E., Adhikari, Bhim M., Ma, Yizhou, Jahanshad, Neda, Thompson, Paul M., McMahon, Francis J., Humphries, Elizabeth M., Burroughs, William, Ament, Seth A., Mitchell, Braxton D., Ma, Tianzhou, Chen, Shuo, Medland, Sarah E., Blangero, John, Hong, L. Elliot and Kochunov, Peter (2024). Accelerating heritability, genetic correlation, and genome‐wide association imaging genetic analyses in complex pedigrees. Human Brain Mapping, 45 (17) e70044, 1-15. doi: 10.1002/hbm.70044 |
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2024 Journal Article The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxietyMonistrol-Mula, Anna, Felez-Nobrega, Mireia, Byrne, Enda M., Lind, Penelope A., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Colodro-Conde, Lucía and Mitchell, Brittany L. (2024). The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety. Psychological Medicine, 54 (15), 4140-4149. doi: 10.1017/s0033291724001983 |
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2024 Journal Article Cardiomyopathies in 100,000 genomes project: interval evaluation improves diagnostic yield and informs strategies for ongoing gene discoveryJosephs, Katherine S., Seaby, Eleanor G., May, Philippa, Theotokis, Pantazis, Yu, Jing, Andreou, Avgi, Sinclair, Hannah, Morris-Rosendahl, Deborah, Thomas, Ellen R. A., Ennis, Sarah, Roberts, Angharad M. and Ware, James S. (2024). Cardiomyopathies in 100,000 genomes project: interval evaluation improves diagnostic yield and informs strategies for ongoing gene discovery. Genome Medicine, 16 (1) 125. doi: 10.1186/s13073-024-01390-9 |
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2024 Journal Article The Circulating Methylome in Childhood-Onset Inflammatory Bowel DiseaseNoble, Alexandra, Adams, Alex, Nowak, Jan, Cheng, Guo, Nayak, Komal, Quinn, Aisling, Kristiansen, Mark, Kalla, Rahul, Ventham, Nicholas T., Giachero, Federica, Jayamanne, Chamara, Hansen, Richard, Hold, Georgina L., El-Omar, Emad, Croft, Nicholas M., Wilson, David, Beattie, R. Mark, Ashton, James J., Zilbauer, Matthias, Ennis, Sarah, Uhlig, Holm H. and Satsangi, Jack (2024). The Circulating Methylome in Childhood-Onset Inflammatory Bowel Disease. Journal of Crohns & Colitis jjae157. doi: 10.1093/ecco-jcc/jjae157 |
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2024 Journal Article Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architectureMorey, Rajendra A., Zheng, Yuanchao, Bayly, Henry, Sun, Delin, Garrett, Melanie E., Gasperi, Marianna, Maihofer, Adam X., Baird, C. Lexi, Grasby, Katrina L., Huggins, Ashley A., Haswell, Courtney C., Thompson, Paul M., Medland, Sarah, Gustavson, Daniel E., Panizzon, Matthew S., Kremen, William S., Nievergelt, Caroline M., Ashley-Koch, Allison E. and Logue, Mark W. (2024). Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture. Translational Psychiatry, 14 (1) 451, 451. doi: 10.1038/s41398-024-03152-y |
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2024 Journal Article Anorexia nervosa polygenic risk, beyond diagnoses: relationship with adolescent disordered eating and behaviors in an Australian female twin populationCurtis, Madeleine, Colodro-Conde, Lucia, Medland, Sarah E., Gordon, Scott, Martin, Nicholas G., Wade, Tracey D. and Cohen-Woods, Sarah (2024). Anorexia nervosa polygenic risk, beyond diagnoses: relationship with adolescent disordered eating and behaviors in an Australian female twin population. Psychological Medicine, 54 (13), 3646-3654. doi: 10.1017/s0033291724001727 |
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2024 Journal Article Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestriesGarcía-Marín, Luis M., Campos, Adrian I., Diaz-Torres, Santiago, Rabinowitz, Jill A., Ceja, Zuriel, Mitchell, Brittany L., Grasby, Katrina L., Thorp, Jackson G., Agartz, Ingrid, Alhusaini, Saud, Ames, David, Amouyel, Philippe, Andreassen, Ole A., Arfanakis, Konstantinos, Arias-Vasquez, Alejandro, Armstrong, Nicola J., Athanasiu, Lavinia, Bastin, Mark E., Beiser, Alexa S., Bennett, David A., Bis, Joshua C., Boks, Marco P. M., Boomsma, Dorret I., Brodaty, Henry, Brouwer, Rachel M., Buitelaar, Jan K., Burkhardt, Ralph, Cahn, Wiepke, Calhoun, Vince D. ... Rentería, Miguel E. (2024). Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. Nature Genetics, 56 (11), 2333-2344. doi: 10.1038/s41588-024-01951-z |
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2024 Journal Article Monoallelic de novo variants in DDX17 cause a neurodevelopmental disorderSeaby, Eleanor G., Godwin, Annie, Meyer-Dilhet, Geraldine, Clerc, Valentine, Grand, Xavier, Fletcher, Tia, Monteiro, Laloe, Kerkhofs, Martijn, Carelli, Valerio, Palombo, Flavia, Seri, Marco, Olivucci, Giulia, Grippa, Mina, Ciaccio, Claudia, D'Arrigo, Stefano, Iascone, Maria, Bermudez, Marion, Fischer, Jan, Di Donato, Nataliya, Goesswein, Sophie, Leung, Marco L., Koboldt, Daniel C., Myers, Cortlandt, Arnadottir, Gudny Anna, Stefansson, Kari, Sulem, Patrick, Goldberg, Ethan M., Bruel, Ange-Line, Tran-Mau-Them, Frederic ... Ennis, Sarah (2024). Monoallelic de novo variants in DDX17 cause a neurodevelopmental disorder. Brain, 148 (4), 1155-1168. doi: 10.1093/brain/awae320 |
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2024 Journal Article Genetic architecture reconciles linkage and association studies of complex traitsSidorenko, Julia, Couvy-Duchesne, Baptiste, Kemper, Kathryn E., Moen, Gunn-Helen, Bhatta, Laxmi, Åsvold, Bjørn Olav, Mägi, Reedik, Estonian Biobank Research Team, Ani, Alireza, Wang, Rujia, Nolte, Ilja M., Lifelines Cohort Study, Nolte, Ilja M., Gordon, Scott, Hayward, Caroline, Campbell, Archie, Benjamin, Daniel J., Cesarini, David, Evans, David M., Goddard, Michael E., Haley, Chris S., Porteous, David, Medland, Sarah E., Martin, Nicholas G., Snieder, Harold, Metspalu, Andres, Hveem, Kristian, Brumpton, Ben, Visscher, Peter M. and Yengo, Loic (2024). Genetic architecture reconciles linkage and association studies of complex traits. Nature Genetics, 56 (11), 2352-2360. doi: 10.1038/s41588-024-01940-2 |
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2024 Journal Article Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohortsAdams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Kõiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 54 (12), 3459-3468. doi: 10.1017/s0033291724001880 |
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2024 Journal Article Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depressionCrouse, Jacob J., Park, Shin Ho, Byrne, Enda M., Mitchell, Brittany L., Scott, Jan, Medland, Sarah E., Lin, Tian, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2024). Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. Molecular Psychiatry, 29 (9), 2765-2773. doi: 10.1038/s41380-024-02492-x |
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2024 Journal Article Large‐scale analysis of structural brain asymmetries during neurodevelopment: associations with age and sex in 4265 children and adolescentsKurth, F., Schijven, D., van den Heuvel, O. A., Hoogman, M., van Rooij, D., Stein, D. J., Buitelaar, J. K., Bölte, S., Auzias, G., Kushki, A., Venkatasubramanian, G., Rubia, K., Bollmann, S., Isaksson, J., Jaspers‐Fayer, F., Marsh, R., Batistuzzo, M. C., Arnold, P. D., Bressan, R. A., Stewart, S. E., Gruner, P., Sorensen, L., Pan, P. M., Silk, T. J., Gur, R. C., Cubillo, A. I., Haavik, J., O'Gorman Tuura, R. L., Hartman, C. A. ... Luders, E. (2024). Large‐scale analysis of structural brain asymmetries during neurodevelopment: associations with age and sex in 4265 children and adolescents. Human Brain Mapping, 45 (11) e26754, e26754. doi: 10.1002/hbm.26754 |
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2024 Journal Article Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrumKentistou, Katherine A., Kaisinger, Lena R., Stankovic, Stasa, Vaudel, Marc, Mendes de Oliveira, Edson, Messina, Andrea, Walters, Robin G., Liu, Xiaoxi, Busch, Alexander S., Helgason, Hannes, Thompson, Deborah J., Santoni, Federico, Petricek, Konstantin M., Zouaghi, Yassine, Huang-Doran, Isabel, Gudbjartsson, Daniel F., Bratland, Eirik, Lin, Kuang, Gardner, Eugene J., Zhao, Yajie, Jia, Raina Y., Terao, Chikashi, Riggan, Marjorie J., Bolla, Manjeet K., Yazdanpanah, Mojgan, Yazdanpanah, Nahid, Bradfield, Jonathan P., Broer, Linda, Campbell, Archie ... The China Kadoorie Biobank Collaborative Group (2024). Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Nature Genetics, 56 (8), 1-2. doi: 10.1038/s41588-024-01857-w |
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2024 Journal Article Genetic analyses point to alterations in immune-related pathways underpinning the association between psychiatric disorders and COVID-19Monistrol-Mula, Anna, Diaz-Torres, Santiago, Felez-Nobrega, Mireia, Haro, Josep Maria, Medland, Sarah E. and Mitchell, Brittany L. (2024). Genetic analyses point to alterations in immune-related pathways underpinning the association between psychiatric disorders and COVID-19. Molecular Psychiatry, 30 (1) 3528, 29-36. doi: 10.1038/s41380-024-02643-0 |
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2024 Journal Article Understanding the genetic complexity of puberty timing across the allele frequency spectrumKentistou, Katherine A., Kaisinger, Lena R., Stankovic, Stasa, Vaudel, Marc, Mendes de Oliveira, Edson, Messina, Andrea, Walters, Robin G., Liu, Xiaoxi, Busch, Alexander S., Helgason, Hannes, Thompson, Deborah J., Santoni, Federico, Petricek, Konstantin M., Zouaghi, Yassine, Huang-Doran, Isabel, Gudbjartsson, Daniel F., Bratland, Eirik, Lin, Kuang, Gardner, Eugene J., Zhao, Yajie, Jia, Raina Y., Terao, Chikashi, Riggan, Marjorie J., Bolla, Manjeet K., Yazdanpanah, Mojgan, Yazdanpanah, Nahid, Bradfield, Jonathan P., Broer, Linda, Campbell, Archie ... The China Kadoorie Biobank Collaborative Group (2024). Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Nature Genetics, 56 (7), 1-15. doi: 10.1038/s41588-024-01798-4 |
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2024 Journal Article Heritability of cerebellar subregion volumes in adolescent and young adult twinsStrike, Lachlan T., Kerestes, Rebecca, McMahon, Katie L., de Zubicaray, Greig I., Harding, Ian H. and Medland, Sarah E. (2024). Heritability of cerebellar subregion volumes in adolescent and young adult twins. Human Brain Mapping, 45 (8) e26717, 1-14. doi: 10.1002/hbm.26717 |
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2024 Journal Article Genetic variants for head size share genes and pathways with cancerKnol, Maria J., Poot, Raymond A., Evans, Tavia E., Satizabal, Claudia L., Mishra, Aniket, Sargurupremraj, Muralidharan, van der Auwera, Sandra, Duperron, Marie-Gabrielle, Jian, Xueqiu, Hostettler, Isabel C., van Dam-Nolen, Dianne H.K., Lamballais, Sander, Pawlak, Mikolaj A., Lewis, Cora E., Carrion-Castillo, Amaia, van Erp, Theo G.M., Reinbold, Céline S., Shin, Jean, Scholz, Markus, Håberg, Asta K., Kämpe, Anders, Li, Gloria H.Y., Avinun, Reut, Atkins, Joshua R., Hsu, Fang-Chi, Amod, Alyssa R., Lam, Max, Tsuchida, Ami, Teunissen, Mariël W.A. ... The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium (2024). Genetic variants for head size share genes and pathways with cancer. Cell Reports Medicine, 5 (5) 101529, 101529. doi: 10.1016/j.xcrm.2024.101529 |
