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2021

Journal Article

Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults

Crouse, Jacob J., Ho, Nicholas, Scott, Jan, Martin, Nicholas G., Couvy-Duchesne, Baptiste, Hermens, Daniel F., Parker, Richard, Gillespie, Nathan A., Medland, Sarah E. and Hickie, Ian B. (2021). Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults. Translational Psychiatry, 11 (1) 285, 285. doi: 10.1038/s41398-021-01390-y

Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults

2021

Journal Article

Ileal transcriptomic analysis in paediatric Crohn's disease reveals IL17- and NOD-signalling expression signatures in treatment-naive patients and identifies epithelial cells driving differentially expressed genes

Ashton, James J., Boukas, Konstantinos, Davies, James, Stafford, Imogen S., Vallejo, Andres F., Haggarty, Rachel, Coelho, Tracy A. F., Batra, Akshay, Afzal, Nadeem A., Vadgama, Bhumita, Williams, Anthony P., Beattie, R. Mark, Polak, Marta E. and Ennis, Sarah (2021). Ileal transcriptomic analysis in paediatric Crohn's disease reveals IL17- and NOD-signalling expression signatures in treatment-naive patients and identifies epithelial cells driving differentially expressed genes. Journal of Crohn's and Colitis, 15 (5), 774-786. doi: 10.1093/ecco-jcc/jjaa236

Ileal transcriptomic analysis in paediatric Crohn's disease reveals IL17- and NOD-signalling expression signatures in treatment-naive patients and identifies epithelial cells driving differentially expressed genes

2021

Journal Article

Introduction to the special issue on statistical genetic methods for human complex traits

Evans, David M., Medland, Sarah E. and Prom-Wormley, Elizabeth (2021). Introduction to the special issue on statistical genetic methods for human complex traits. Behavior Genetics, 51 (3), 165-169. doi: 10.1007/s10519-021-10057-9

Introduction to the special issue on statistical genetic methods for human complex traits

2021

Journal Article

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

2021

Journal Article

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

2021

Journal Article

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

Sønderby, Ida E., van der Meer, Dennis, Moreau, Clara, Kaufmann, Tobias, Walters, G Bragi, Ellegaard, Maria, Abdellaoui, Abdel, Ames, David, Amunts, Katrin, Andersson, Micael, Armstrong, Nicola J., Bernard, Manon, Blackburn, Nicholas B., Blangero, John, Boomsma, Dorret I., Brodaty, Henry, Brouwer, Rachel M., Bülow, Robin, Bøen, Rune, Cahn, Wiepke, Calhoun, Vince D., Caspers, Svenja, Ching, Christopher R. K., Cichon, Sven, Ciufolini, Simone, Crespo-Facorro, Benedicto, Curran, Joanne E., Dale, Anders M., Dalvie, Shareefa ... ENIGMA-CNV working group (2021). 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans. Translational Psychiatry, 11 (1) 182, 1-16. doi: 10.1038/s41398-021-01213-0

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans

2021

Journal Article

Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease

Coelho, Tracy, Sonnenberg-Riethmacher, Eva, Gao, Yifang, Mossotto, Enrico, Khojanazarov, Alisher, Griffin, Annie, Mukanova, Saida, Ashimkhanova, Aiymkul, Haggarty, Rachel, Borissenko, Anton, Ashton, James J., Stafford, Imogen S., Batra, Akshay, Afzal, Nadeem A., Stanton, Michael P., Vadgama, Bhumita, Adrisova, Kapura, Beattie, Robert M., Williams, Anthony P., Ennis, Sarah and Riethmacher, Dieter (2021). Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease. Scientific Reports, 11 (1) 6194, 1-13. doi: 10.1038/s41598-021-85096-7

Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease

2021

Journal Article

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color

Simcoe, Mark, Valdes, Ana, Liu, Fan, Furlotte, Nicholas A., Evans, David M., Hemani, Gibran, Ring, Susan M., Smith, George Davey, Duffy, David L., Zhu, Gu, Gordon, Scott D., Medland, Sarah E., Vuckovic, Dragana, Girotto, Giorgia, Sala, Cinzia, Catamo, Eulalia, Concas, Maria Pina, Brumat, Marco, Gasparini, Paolo, Toniolo, Daniela, Cocca, Massimiliano, Robino, Antonietta, Yazar, Seyhan, Hewitt, Alex, Wu, Wenting, Kraft, Peter, Hammond, Christopher J., Shi, Yuan, Chen, Yan ... the International Visible Trait Genetics Consortium (2021). Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color. Science Advances, 7 (11) abd1239, eabd1239. doi: 10.1126/sciadv.abd1239

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color

2021

Journal Article

Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts

Campos, Adrian I., Thompson, Paul M., Veltman, Dick J., Pozzi, Elena, van Veltzen, Laura S., Jahanshad, Neda, Adams, Mark J., Baune, Bernhard T., Berger, Klaus, Brosch, Katharina, Bülow, Robin, Connolly, Colm G., Dannlowski, Udo, Davey, Christopher G., de Zubicaray, Greig I., Dima, Danai, Erwin-Grabner, Tracy, Evans, Jennifer W., Fu, Cynthia H.Y., Gotlib, Ian H., Goya-Maldonado, Roberto, Grabe, Hans J., Grotegerd, Dominik, Harris, Matthew A., Harrison, Ben J., Hatton, Sean N., Hermesdorf, Marco, Hickie, Ian B., Ho, Tiffany C. ... Rentería, Miguel E. (2021). Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts. Biological Psychiatry, 90 (4), 243-252. doi: 10.1016/j.biopsych.2021.03.015

Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts

2021

Journal Article

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

Scott, Jan, Crouse, Jacob J., Ho, Nicholas, Carpenter, Joanne, Martin, Nicholas, Medland, Sarah, Parker, Richard, Byrne, Enda, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Merikangas, Kathleen, Gillespie, Nathan A. and Hickie, Ian (2021). Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?. Bipolar Disorders, 23 (6), 584-594. doi: 10.1111/bdi.13067

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

2021

Journal Article

Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs

Sønderby, Ida E, Ching, Christopher R. K., Thomopoulos, Sophia I., van der Meer, Dennis, Sun, Daqiang, Villalon-Reina, Julio E., Agartz, Ingrid, Amunts, Katrin, Arango, Celso, Armstrong, Nicola J., Ayesa-Arriola, Rosa, Bakker, Geor, Bassett, Anne S., Boomsma, Dorret I., Bülow, Robin, Butcher, Nancy J., Calhoun, Vince D., Caspers, Svenja, Chow, Eva W. C., Cichon, Sven, Ciufolini, Simone, Craig, Michael C., Crespo-Facorro, Benedicto, Cunningham, Adam C., Dale, Anders M., Dazzan, Paola, de Zubicaray, Greig I., Djurovic, Srdjan, Doherty, Joanne L. ... Wright, Margaret (2021). Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs. Human Brain Mapping, 43 (1) hbm.25354, 300-328. doi: 10.1002/hbm.25354

Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs

2021

Journal Article

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years

Frangou, Sophia, Modabbernia, Amirhossein, Williams, Steven C. R., Papachristou, Efstathios, Doucet, Gaelle E., Agartz, Ingrid, Aghajani, Moji, Akudjedu, Theophilus N., Albajes-Eizagirre, Anton, Alnaes, Dag, Alpert, Kathryn I, Andersson, Micael, Andreasen, Nancy C, Andreassen, Ole A, Asherson, Philip, Banaschewski, Tobias, Bargallo, Nuria, Baumeister, Sarah, Baur-Streubel, Ramona, Bertolino, Alessandro, Bonvino, Aurora, Boomsma, Dorret I, Borgwardt, Stefan, Bourque, Josiane, Brandeis, Daniel, Breier, Alan, Brodaty, Henry, Brouwer, Rachel M, Buitelaar, Jan K ... Dima, Danai (2021). Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years. Human Brain Mapping, 43 (1) hbm.25364, 431-451. doi: 10.1002/hbm.25364

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years

2021

Journal Article

The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption

Hwang, Liang-Dar, Mitchell, Brittany L., Medland, Sarah E., Martin, Nicholas G., Neale, Michael C. and Evans, David M. (2021). The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption. Behavior Genetics, 51 (3), 223-236. doi: 10.1007/s10519-021-10044-0

The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption

2021

Journal Article

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years

Dima, Danai, Modabbernia, Amirhossein, Papachristou, Efstathios, Doucet, Gaelle E., Agartz, Ingrid, Aghajani, Moji, Akudjedu, Theophilus N., Albajes-Eizagirre, Anton, Alnaes, Dag, Alpert, Kathryn I., Andersson, Micael, Andreasen, Nancy C., Andreassen, Ole A., Asherson, Philip, Banaschewski, Tobias, Bargallo, Nuria, Baumeister, Sarah, Baur-Streubel, Ramona, Bertolino, Alessandro, Bonvino, Aurora, Boomsma, Dorret I., Borgwardt, Stefan, Bourque, Josiane, Brandeis, Daniel, Breier, Alan, Brodaty, Henry, Brouwer, Rachel M., Buitelaar, Jan K., Busatto, Geraldo F. ... Karolinska Schizophrenia Project (KaSP) (2021). Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years. Human Brain Mapping, 43 (1) hbm.25320, 452-469. doi: 10.1002/hbm.25320

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years

2021

Journal Article

Digit ratio (2D:4D) and handedness: A meta-analysis of the available literature

Richards, Gareth, Medland, Sarah E. and Beaton, Alan A. (2021). Digit ratio (2D:4D) and handedness: A meta-analysis of the available literature. Laterality, 26 (4), 421-484. doi: 10.1080/1357650X.2020.1862141

Digit ratio (2D:4D) and handedness: A meta-analysis of the available literature

2021

Journal Article

16Up: Outline of a study investigating wellbeing and information and communication technology use in adolescent twins

Mitchell, Brittany L., Kirk, Katherine M., McAloney, Kerrie, Wright, Margaret J., Davenport, Tracey A., Hermens, Daniel F., Scott, James G., McGrath, John J., Gillespie, Nathan A., Carpenter, Joanne S., O’Callaghan, Victoria S., Medland, Sarah, Christensen, Helen, Martin, Nicholas G., Burns, Jane M. and Hickie, Ian B. (2021). 16Up: Outline of a study investigating wellbeing and information and communication technology use in adolescent twins. Twin Research and Human Genetics, 23 (6) PII S1832427420000833, 1-13. doi: 10.1017/thg.2020.83

16Up: Outline of a study investigating wellbeing and information and communication technology use in adolescent twins

2021

Journal Article

Investigating the causal nature of the relationship of subcortical brain volume with smoking and alcohol use

Logtenberg, Emma, Overbeek, Martin F., Pasman, Joëlle A., Abdellaoui, Abdel, Luijten, Maartje, Van Holst, Ruth J., Vink, Jacqueline M., Denys, Damiaan, Medland, Sarah E., Verweij, Karin J. H. and Treur, Jorien L. (2021). Investigating the causal nature of the relationship of subcortical brain volume with smoking and alcohol use. British Journal of Psychiatry, 221 (1) PII S0007125021000817, 1-9. doi: 10.1192/bjp.2021.81

Investigating the causal nature of the relationship of subcortical brain volume with smoking and alcohol use

2021

Journal Article

Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity

Smit, Dirk J. A., Andreassen, Ole A., Boomsma, Dorret I., Burwell, Scott J., Chorlian, David B., de Geus, Eco J. C., Elvsåshagen, Torbjørn, Gordon, Reyna L., Harper, Jeremy, Hegerl, Ulrich, Hensch, Tilman, Iacono, William G., Jawinski, Philippe, Jönsson, Erik G., Luykx, Jurjen J., Magne, Cyrille L., Malone, Stephen M., Medland, Sarah E., Meyers, Jacquelyn L., Moberget, Torgeir, Porjesz, Bernice, Sander, Christian, Sisodiya, Sanjay M., Thompson, Paul M., van Beijsterveldt, Catharina E. M., van Dellen, Edwin, Via, Marc and Wright, Margaret J. (2021). Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity. Brain and Behavior, 11 (8) e02188, e02188. doi: 10.1002/brb3.2188

Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity

2021

Journal Article

Growth failure is rare in a contemporary cohort of paediatric inflammatory bowel disease patients

Ashton, James J., Green, Zachary, Young, Aneurin, Borca, Florina, Coelho, Tracy, Batra, Akshay, Afzal, Nadeem A., Ennis, Sarah, Johnson, Mark J. and Beattie, R. Mark (2021). Growth failure is rare in a contemporary cohort of paediatric inflammatory bowel disease patients. Acta Paediatrica, 110 (1), 326-334. doi: 10.1111/apa.15383

Growth failure is rare in a contemporary cohort of paediatric inflammatory bowel disease patients

2021

Journal Article

Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets

Postema, Merel C., Hoogman, Martine, Ambrosino, Sara, Asherson, Philip, Banaschewski, Tobias, Bandeira, Cibele E., Baranov, Alexandr, Bau, Claiton H.D., Baumeister, Sarah, Baur-Streubel, Ramona, Bellgrove, Mark A., Biederman, Joseph, Bralten, Janita, Brandeis, Daniel, Brem, Silvia, Buitelaar, Jan K., Busatto, Geraldo F., Castellanos, Francisco X., Cercignani, Mara, Chaim-Avancini, Tiffany M., Chantiluke, Kaylita C., Christakou, Anastasia, Coghill, David, Conzelmann, Annette, Cubillo, Ana I., Cupertino, Renata B., de Zeeuw, Patrick, Doyle, Alysa E., Durston, Sarah ... Francks, Clyde (2021). Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets. Journal of Child Psychology and Psychiatry and Allied Disciplines, 62 (10) jcpp.13396, 1202-1219. doi: 10.1111/jcpp.13396

Analysis of structural brain asymmetries in attention-deficit/hyperactivity disorder in 39 datasets