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2003 Other Outputs Compositions comprising nitric oxide donors and opioid analgesicsSmith, M. T., Brown, L. C., Harvey, M. and Williams, C. M. (2003). Compositions comprising nitric oxide donors and opioid analgesics. PCT/AU03/00335. |
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2003 Journal Article Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: Mechanistic studies in embryonic cultured hippocampal neuronesHemstapat, K., Monteith, G. R., Smith, D. and Smith, M. T. (2003). Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: Mechanistic studies in embryonic cultured hippocampal neurones. Anesthesia & Analgesia, 97 (2), 494-505. doi: 10.1213/01.ANE.0000059225.40049.99 |
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2003 Journal Article The neuroexcitatory morphine metabolite, morphine-3-glucuronide (M3G), is not neurotoxic in primary cultures of either hippocampal or cerebellar granule neuronesHemstapat, K., Smith, S. A., Monteith, G. R. and Smith, M. T. (2003). The neuroexcitatory morphine metabolite, morphine-3-glucuronide (M3G), is not neurotoxic in primary cultures of either hippocampal or cerebellar granule neurones. Pharmacology & Toxicology, 93 (4), 197-200. doi: 10.1034/j.1600-0773.2003.930408.x |
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2003 Conference Publication Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the Zucker ratTsui, D. Y., Hawes, S., Patterson, M. and Smith, M. T. (2003). Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the Zucker rat. Annual Scientific Meeting of Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists 2003, Sydney, 30 November - 3 December 2003. Melbourne: ASCEPT. |
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2003 Conference Publication Quantification of morphine, oxycodone, morphine-3-glucuronide and noroxycodone in rat serum by high performance liquid chromatography (HPLC-electrospray mass spectrometry (EMS)Edwards, S. R. and Smith, M. T. (2003). Quantification of morphine, oxycodone, morphine-3-glucuronide and noroxycodone in rat serum by high performance liquid chromatography (HPLC-electrospray mass spectrometry (EMS). Annual Scientific Meeting of ASCEPT 2003, Sydney, 30 November - 3 December 2003. Melbourne: ASCEPT. |
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2003 Conference Publication A fresh approach to neuropathic pain management: From the animal model to the patientMoore, B., Azzopardi, J., Cabot, P. J., Gray, P., Roufogalis, B. and Smith, M. T. (2003). A fresh approach to neuropathic pain management: From the animal model to the patient. Combined meeting of the Australian Pain Society 24th ASM and New Zealand Pain Society 10th ASM, Christchurch, NZ, 9-13 March 2003. Sydney: Australian Pain Society. |
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2003 Book Chapter Neurobiology of Pain: Identification of novel targets for new pain management medicationsSmith, M. T. (2003). Neurobiology of Pain: Identification of novel targets for new pain management medications. Molecular Pathomechanisms and New Trends in Drug Research. (pp. 302-318) edited by G. Keri and I. Toth. London & New York: Taylor & Francis. |
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2003 Journal Article Managing diabetic neuropathySmith, M. T. (2003). Managing diabetic neuropathy. Australian Pharmacist, 22 (10), 782-787. |
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2003 Conference Publication Serum concentrations of metabolically-derived oxymorphone are insignificant in diabetic and non-diabetic adult male Dark Agouti rats following subcutaneous oxycodone bolus administration: Comparison with Sprague-Dawley ratsHuang, L., Le, L., Edwards, S. R. and Smith, M. T. (2003). Serum concentrations of metabolically-derived oxymorphone are insignificant in diabetic and non-diabetic adult male Dark Agouti rats following subcutaneous oxycodone bolus administration: Comparison with Sprague-Dawley rats. Annual Scientific Meeting of ASCEPT, Sydney, 30 November - 3 December 2003. Melbourne: ASCEPT. |
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2003 Journal Article The streptozotocin-diabetic rat as a model of the chronic complications of human diabetesWei, M., Ong, L., Smith, M. T., Ross, F. B., Schmid, K., Hoey, A., Burstow, D. J. and Brown, L. C. (2003). The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes. Heart, Lung and Circulation, 2003 (12), 44-50. doi: 10.1046/j.1444-2892.2003.00160.x |
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2002 Journal Article The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices.Smith, M. T., Cabot, P. J., Ross, F. B., Robertson, A. D. and Lewis, R. J. (2002). The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices.. Pain, 96 (1-2), 119-127. doi: 10.1016/S0304-3959(01)00436-5 |
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2002 Conference Publication Supraspinally administered oxycodone has intrinsic anti-allodynic effects for the alleviation of tactile allodynia in adult male rats with streptozotocin-induced diabetesSmith, M. T., Patterson, M. and Ross, F. B. (2002). Supraspinally administered oxycodone has intrinsic anti-allodynic effects for the alleviation of tactile allodynia in adult male rats with streptozotocin-induced diabetes. 10th World Congress on Pain, San Diego, 17-22 August 2002. Seattle: IASP Press. |
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2002 Conference Publication Anti-allodynic efficacy of the conopeptide, MR1A, in rats with neuropathic painNielsen, C., Ross, F. B., Lewis, R. J., Drinkwater, R. D. and Smith, M. T. (2002). Anti-allodynic efficacy of the conopeptide, MR1A, in rats with neuropathic pain. 10th World Congress on Pain, San Diego, 17-22 Aug. 2002. Seattle: IASP Press. |
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2002 Conference Publication Investigation of the role of dynorphin-A in mediating morphine-3-glucuronide's neuro-excitatory effectsHemstapat, K., Monteith, G. R. and Smith, M. T. (2002). Investigation of the role of dynorphin-A in mediating morphine-3-glucuronide's neuro-excitatory effects. 10th World Congress on Pain, San Diego, 17-22 Aug. 2002. Seattle: IASP Press. |
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2002 Conference Publication Electrolyte removal from artificial CSF by HPLC to restore ESI-MS/MS signal intensity in quantification of morphine and its glucuronide metabolitesWells, J. A., Punjanon, T. and Smith, M. T. (2002). Electrolyte removal from artificial CSF by HPLC to restore ESI-MS/MS signal intensity in quantification of morphine and its glucuronide metabolites. 10th World Congress on Pain, San Diego, 17-22 Aug. 2002. Seattle: IASP Press. |
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2002 Conference Publication Anti-allodynic efficacy of the x-conipeptide, MR1A, in rats with neuropathic painNielsen, C., Ross, F. B., Lewis, R. J., Drinkwater, R. D. and Smith, M. T. (2002). Anti-allodynic efficacy of the x-conipeptide, MR1A, in rats with neuropathic pain. AHMR Congress 2002, Melbourne, 24-29 Nov. 2002. Melbourne: NHMRC. |
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2002 Conference Publication Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by ICV morphine in adult male ratsMather, L. E., Punjanon, T. and Smith, M. T. (2002). Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by ICV morphine in adult male rats. 10th World Congress on Pain, San Diego, 17-22 Aug. 2002. Seattle: IASP Press. |
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2002 Conference Publication P/Q and L-type calcium channel blockers abolish morphine-3-glucuronide (M3G)-induced indirect activation of the NMDA receptorHemstapat, K., Monteith, G. R. and Smith, M. T. (2002). P/Q and L-type calcium channel blockers abolish morphine-3-glucuronide (M3G)-induced indirect activation of the NMDA receptor. AHMR Congress 2002, Melbourne, 24-29 Nov. 2002. Melbourne: NHMRC. |
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2002 Conference Publication Serum 17 -oestradiol concentrations are directly correlated with the time to reach peak antinociception in oestradiol-pretreated rats administered prolonged intravenous morphine infusionsLe, L., Chmura, P., Mather, L. E. and Smith, M. T. (2002). Serum 17 -oestradiol concentrations are directly correlated with the time to reach peak antinociception in oestradiol-pretreated rats administered prolonged intravenous morphine infusions. 10th World Congress on Pain, San Diego, 17-22 Aug. 2002. Seattle: IASP Press. |
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2002 Conference Publication In vivo investigation of the effects of intracerebroventricular (ICV) morphine-3-glucuronide (M3G) on von frey paw withdrawal thresholds in ratsLe, L., Hemstapat, K. and Smith, M. T. (2002). In vivo investigation of the effects of intracerebroventricular (ICV) morphine-3-glucuronide (M3G) on von frey paw withdrawal thresholds in rats. AHMR Congress 2002, Melbourne, 24-29 Nov. 2002. Melbourne: NHMRC. |
