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2005

Conference Publication

Investigation of the anti-allodynic and anti-hyperalgesics effects of ACV1 in a rat model of neuropathic pain

Wyse, B. D., Hwang, J. C., Kydd, S., Patterson, M., Nielsen, C. K., Belyea, C., McIntosh, D. and Smith, M. T. (2005). Investigation of the anti-allodynic and anti-hyperalgesics effects of ACV1 in a rat model of neuropathic pain. 11th World Congress on Pain, Sydney, Australia, 21-26 August 2005. Seattle, Wa.: IASP Press.

Investigation of the anti-allodynic and anti-hyperalgesics effects of ACV1 in a rat model of neuropathic pain

2005

Conference Publication

In vivo proof-of-concept study: Commercialisation and regulatory imperatives

Smith, M. T. (2005). In vivo proof-of-concept study: Commercialisation and regulatory imperatives. Joint Meeting of ASCEPT and APSA, Melbourne, 4-7 December 2005. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

In vivo proof-of-concept study: Commercialisation and regulatory imperatives

2005

Journal Article

Co-administration of oxycodone and morphine and analgesic synergy re-examined

Smith, MT and de la Iglesia, FA (2005). Co-administration of oxycodone and morphine and analgesic synergy re-examined. British Journal of Clinical Pharmacology, 59 (4), 486-487. doi: 10.1111/j.1365-2125.2005.02345_1.x

Co-administration of oxycodone and morphine and analgesic synergy re-examined

2005

Journal Article

Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetes

Huang, L., Edwards, S. R. and Smith, M. T. (2005). Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetes. Pharmaceutical Research, 22 (9), 1489-1498. doi: 10.1007/s11095-005-6154-y

Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetes

2005

Conference Publication

What you and your patient need to know about opioids

Smith, M. T., Moore, B. and Molloy, A. (2005). What you and your patient need to know about opioids. Partners in Pain: Patients, Clinicians and Pain Management, Sydney, Australia, 18-19 August, 2005.

What you and your patient need to know about opioids

2004

Conference Publication

Opioid rotation and methadone: Pharmacokinetic considerations

Smith, M. T., Fleming, J. A. and Connor, M. (2004). Opioid rotation and methadone: Pharmacokinetic considerations. 2004 ANZCA Annual Scientific Meeting, Perth, Western Australia, 1-5 May, 2004. Melbourne, Vic, Australia: Australian and New Zealand College of Anaesthetists (ANZCA).

Opioid rotation and methadone: Pharmacokinetic considerations

2004

Journal Article

Deletion of guanine nucleotide binding protein az subunit in mice induces a gene dose dependent tolerance to morphine

Leck, KJ, Bartlett, SE, Smith, MT, Megirian, D, Holgate, J, Powell, KL, Matthaei, KI and Hendry, IA (2004). Deletion of guanine nucleotide binding protein az subunit in mice induces a gene dose dependent tolerance to morphine. Neuropharmacology, 46 (6), 836-846. doi: 10.1016/j.neuropharm.2003.11.024

Deletion of guanine nucleotide binding protein az subunit in mice induces a gene dose dependent tolerance to morphine

2004

Conference Publication

Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the zucker rat

Tsui, D. Y., Hawes, S., Patterson, M. and Smith, M. T. (2004). Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the zucker rat. Clinical Pharmacology and Therapeutics 2004, Brisbane, 1-6 August, 2004. Australia: Blackwell Publishing.

Longitudinal investigation of the antinociceptive potency of oxycodone and morphine in the zucker rat

2004

Conference Publication

Determination of morphine, oxycodone, morphine-3-glucuronide, & noroxycodone concentrations in rat serum by liquid chromatography (LC) - electrospray mass spectrometry (EMS)

Edwards, S. R. and Smith, M. T. (2004). Determination of morphine, oxycodone, morphine-3-glucuronide, & noroxycodone concentrations in rat serum by liquid chromatography (LC) - electrospray mass spectrometry (EMS). CPT2004, Brisbane, 1-6 August 2004. Australia: Blackwell Publishing.

Determination of morphine, oxycodone, morphine-3-glucuronide, & noroxycodone concentrations in rat serum by liquid chromatography (LC) - electrospray mass spectrometry (EMS)

2004

Conference Publication

Comparative pharmacokinetics and metabolism of subcutaneous oxycodone in male dark agouti relative to sprague-dawley rats

Huang, L., Edwards, S. R. and Smith, M. T. (2004). Comparative pharmacokinetics and metabolism of subcutaneous oxycodone in male dark agouti relative to sprague-dawley rats. CTP 2004, Brisbane, 1-6 August 2004. Australia: Blackwell Publishing Asia.

Comparative pharmacokinetics and metabolism of subcutaneous oxycodone in male dark agouti relative to sprague-dawley rats

2004

Conference Publication

Oxycodone: A dose ranging pharmacodynamic study in dogs

Bubb, L. M., Keates, H. L. and Smith, M. T. (2004). Oxycodone: A dose ranging pharmacodynamic study in dogs. Proc. of Assoc. of Veterinary Anaesthetists, Vienna, Austria, 16-17 September 2004. Austria:

Oxycodone: A dose ranging pharmacodynamic study in dogs

2004

Conference Publication

Anti-allodynic effects of Xen2174 in rats with neuropathy. Abstract

Smith, M. T., Nielsen, C., Lewis, R., Alewood, D. and Drinkwater, R. D. (2004). Anti-allodynic effects of Xen2174 in rats with neuropathy. Abstract. ANZCA Annual Scientific Meeting, Perth, Western Australia, 1-5 May, 2004. Australia: ANZCA.

Anti-allodynic effects of Xen2174 in rats with neuropathy. Abstract

2004

Conference Publication

Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain

Nielsen, C., Smith, M. T., Lewis, R., Alewood, D. and Drinkwater, R. D. (2004). Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain. CPT2004: 8th World Congress on Clinical Pharmacology & Therapeutics, Brisbane, Qld, Australia, 1-6 August, 2004. Oxford, United Kingdom: Blackwell Scientific Publications. doi: 10.1111/j.1440-1681.2004.cep_4027.pdf.x

Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain

2004

Conference Publication

The pro-allodynic effects of morphine-3-glucuronide (M3G) in the rat

Smith, M. T., Le, L., Hemstapat, K., De Cruz, S. E. and Nielsen, C. (2004). The pro-allodynic effects of morphine-3-glucuronide (M3G) in the rat. CTP 2004, Brisbane, 1-6 Aug 2004. Australia: Blackwell Publishing Asia.

The pro-allodynic effects of morphine-3-glucuronide (M3G) in the rat

2004

Conference Publication

Opioids and NMDA receptors: Neuro-excitation and abnormal pain behaviours

Smith, M. T. (2004). Opioids and NMDA receptors: Neuro-excitation and abnormal pain behaviours. ANZCA Annual Scientific Meeting, Perth, 1-5 May 2004. Australia: ANZCA.

Opioids and NMDA receptors: Neuro-excitation and abnormal pain behaviours

2004

Conference Publication

Effect of insulin treatment on diabetic characteristics in the STZ-diabetic rat

Otto, K. J., Wyse, B. D., Cabot, P. J. and Smith, M. T. (2004). Effect of insulin treatment on diabetic characteristics in the STZ-diabetic rat. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 Nov - 1 Dec 2004. Brisbane: Qld Government.

Effect of insulin treatment on diabetic characteristics in the STZ-diabetic rat

2004

Journal Article

Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: Potential application to biomolecular screening

Hemstapat, K, Smith, M. T. and Monteith, G. R. (2004). Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: Potential application to biomolecular screening. Journal of Pharmacological and Toxicological Methods, 49 (2), 81-87. doi: 10.1016/j.vascn.2003.10.002

Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: Potential application to biomolecular screening

2004

Conference Publication

P2.3 longitudinal investigation of the comparative anti-allodynic potencies of oxycodone and morphine in the zucker rat relative to the streptozotocin-induced diabetic rat

Tsui, D.Y., Hawes, S., Patterson, M. and Smith, M. T. (2004). P2.3 longitudinal investigation of the comparative anti-allodynic potencies of oxycodone and morphine in the zucker rat relative to the streptozotocin-induced diabetic rat. 25th Annual Scientific Meeting of the Australian Pain Society, Canberra, 7-10 March 2004. Australia: Australian Pain Society.

P2.3 longitudinal investigation of the comparative anti-allodynic potencies of oxycodone and morphine in the zucker rat relative to the streptozotocin-induced diabetic rat

2004

Conference Publication

The pro-allodynic effects of morphine-3-glucuronide (M3G) appear to be opioid-receptor mediated

Nielsen, C., De Cruz, S. E. and Smith, M. T. (2004). The pro-allodynic effects of morphine-3-glucuronide (M3G) appear to be opioid-receptor mediated. 25th Annual Scientific Meeting of the Australian Pain Society, Canberra, 7-10 March 2004. Australia: Australian Pain Society.

The pro-allodynic effects of morphine-3-glucuronide (M3G) appear to be opioid-receptor mediated

2004

Conference Publication

Assessment of working spatial memory utilising T-maze and Morris water-maze for the study of a rodent model of alzheimer's disease

Patel, A., Smith, M. T. and Cabot, P. J. (2004). Assessment of working spatial memory utilising T-maze and Morris water-maze for the study of a rodent model of alzheimer's disease. 4th Annual Queensland Health and Medical Scientific Meeting, Brisbane, 30 November - 1 December 2004. Brisbane: Qld Government.

Assessment of working spatial memory utilising T-maze and Morris water-maze for the study of a rodent model of alzheimer's disease