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2009 Journal Article X-conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for painBrust, Andreas, Palant, Elka, Croker, Daniel E., Colless, Barbara, Drinkwater, Roger, Patterson, Brad, Schroeder, Christina I., Wilson, David, Nielsen, Carsten K., Smith, Maree T., Alewood, Danne, Alewood, Paul F and Lewis, Richard J. (2009). X-conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain. Journal of Medicinal Chemistry, 52 (22), 6991-7002. doi: 10.1021/jm9003413 |
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2009 Conference Publication Development of XEN2174 and an escalating safety and tolerability study of intrathecal use in oncology patientsBrust, A., Colless, B., Cousins, M., Day, D., Drinkwater, R., Gouke, R., Hughes, D., Lewis, R. J., Martin, W., Nielson, C., Palant, E., Rauck, R., Schmidt, P., Smith, M. T. and Steams, L. J. (2009). Development of XEN2174 and an escalating safety and tolerability study of intrathecal use in oncology patients. Michal Lebl Peptides Breaking Away, Bloomington, Indiana, U.S.A., 7-12 June, 2009. San Diego, C.A. U.S.A.: American Peptide Society. |
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2009 Journal Article Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-dawley rats: Differences between the tail flick and hot plate nociceptive testsSouth, Samantha M., Edwards, Stephen R. and Smith, Maree T. (2009). Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-dawley rats: Differences between the tail flick and hot plate nociceptive tests. Clinical and Experimental Pharmacology and Physiology, 36 (1), 20-28. doi: 10.1111/j.1440-1681.2008.05019.x |
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2009 Conference Publication High-quality, cost-effective preclinical product development solutionsSmith, Maree (2009). High-quality, cost-effective preclinical product development solutions. BIO Korea 2009, Seoul, Korea, 16-18 September 2009. Seoul, Korea: BIO Korea 2009. |
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2009 Conference Publication A study of the application of the Morris water maze to the establishment of a preclinical model of Alzheimer's disease in the ratEdwards, Stephen and Smith, M.T. (2009). A study of the application of the Morris water maze to the establishment of a preclinical model of Alzheimer's disease in the rat. ASCEPT 43rd Annual Scientific Meeting 2009: The Rights of Medicines, Darling Harbour, NSW, Australia, 29 November-2 December 2009. |
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2009 Journal Article Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A (2-17) following spinal and supraspinal routes of administrationHemstapat, K., Le, L., Edwards, S. R. and Smith, M. T. (2009). Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A (2-17) following spinal and supraspinal routes of administration. Pharmacology, Biochemistry and Behaviour, 93 (4), 498-505. doi: 10.1016/j.pbb.2009.06.016 |
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2009 Journal Article Innovation in drug developmentSmith, M.T. (2009). Innovation in drug development. BioSpectrum Asia CRAMS Resources Guide, 52-53. |
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2009 Conference Publication DEVELOPMENT OF XEN2174: NON-CLINICAL STUDIES AND AN OPEN-LABEL I/IIa STUDY OF INTRATHECAL USE IN ONCOLOGY PATIENTS WITH MODERATE TO SEVERE PAINMartin, W., Lewis, R. J., Palant, E., Brust, A., Colless, B., Schmidt, P., Drinkwater, R., Stearns, L. J., Cousins, M., Gouke, R., Hughes, D., Rauck, R., Day, D., Nielsen, C. K. and Smith, M. T. (2009). DEVELOPMENT OF XEN2174: NON-CLINICAL STUDIES AND AN OPEN-LABEL I/IIa STUDY OF INTRATHECAL USE IN ONCOLOGY PATIENTS WITH MODERATE TO SEVERE PAIN. 21st American Peptide Symposium, Bloomington in, Jun 07-12, 2009. HOBOKEN: JOHN WILEY & SONS INC. |
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2008 Journal Article Differences between and combinations of opiods re-visitedSmith, Maree T. (2008). Differences between and combinations of opiods re-visited. Current Opinion in Anaesthesiology, 21 (5), 596-601. doi: 10.1097/ACO.0b013e32830a4c4a |
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2008 Other Outputs Pain-relieving compositions and uses thereforeSmith, M. T. (2008). Pain-relieving compositions and uses therefore. PCT/AU2008/000003: WO/2008/080194. |
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2008 Journal Article An update on the pharmcological management of post-herpetic neuralgia and painful diabetic neuropathyZin, Che S., Nissen, Lisa M., Smith, Maree T., O'Callaghan, James P. and Moore, Brendan J. (2008). An update on the pharmcological management of post-herpetic neuralgia and painful diabetic neuropathy. CNS Drugs, 22 (5), 417-442. doi: 10.2165/00023210-200822050-00005 |
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2008 Journal Article Sex differences in the pharmacokinetics, oxidative metabolism and oral bioactivity of oxycodone in the sprague-dawley ratChan, S., Edwards, S. R., Wyse, B. D. and Smith, M. T. (2008). Sex differences in the pharmacokinetics, oxidative metabolism and oral bioactivity of oxycodone in the sprague-dawley rat. Clinical and Experimental Pharmacology and Physiology, 35 (3), 295-302. doi: 10.1111/j.1440-1681.2007.04821.x |
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2008 Conference Publication Novel strategies in new opioid analgesic developmentSmith, M. T. (2008). Novel strategies in new opioid analgesic development. Combined CME Spring Meeting of Faculty of Pain Medicine, ANZCA, Acute Pain special Interest Group of ANZCA, ASA and NZSA, Acute Pain Special Interest Group of IASP, Ayers Rock, Northern Territory, Australia, 18-20 September 2008. |
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2008 Conference Publication Mechanistic insight into the anti-allodynic effects of PRG150Huang, L., Wyse, B. D. and Smith, M. T. (2008). Mechanistic insight into the anti-allodynic effects of PRG150. 12th World Congress on Pain, Glasgow, Scotland, 17-22 August 2008. |
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2008 Conference Publication Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine, morphine-6-glucuronide and fentanyl in rats Kuo A, Hemstapat K, Wyse BD, Smith MTHemstapat, K., Kuo, A., Smith, M.T. and Wyse, B.D. (2008). Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine, morphine-6-glucuronide and fentanyl in rats Kuo A, Hemstapat K, Wyse BD, Smith MT. 4th Scientific Meeting of the Australian Health and Medical Research Congress, Brisbane, Australia, 16 - 21 November, 2008. |
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2008 Conference Publication Development of novel X-conopeptide inhibitors of the norepinephrine transporter with analgesic potentialLewis, R. J., Palant, E., Brust, A., Colless, B., Schmidt, P., Nielsen, C. K., Smith, M. T. and Drinkwater, R. (2008). Development of novel X-conopeptide inhibitors of the norepinephrine transporter with analgesic potential. 12th World Congress on Pain, Glasgow, Scotland, 17-22 August, 2008. |
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2008 Conference Publication Preclinical development of new drugs for pain treatmentSmith, M. T. (2008). Preclinical development of new drugs for pain treatment. 4th Australian Health and Medical Research Congress, Brisbane, Australia, 16-21 November 2008. Brisbane, Australia: |
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2008 Conference Publication Influence of diet on the longitudinal temporal development of opioid hyposensitivity and tactile allodynia in the Zucker Diabetic Fatty (ZDF) ratOtto, K., Wyse, B. D., South, S. M., Cabot, P. J. and Smith, M. T. (2008). Influence of diet on the longitudinal temporal development of opioid hyposensitivity and tactile allodynia in the Zucker Diabetic Fatty (ZDF) rat. 12th World Congress on Pain, Glasgow, Scotland, 17-22 August 2008. |
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2008 Conference Publication Opioid-induced hyperalgesia, opioid rotation and opioid combinationsSmith, Maree T. (2008). Opioid-induced hyperalgesia, opioid rotation and opioid combinations. Combined CME Spring Meeting of Faculty of Pain Medicine, ANZCA, Acute Pain special Interest Group of ANZCA, ASA and NZSA, Acute Pain Special Interest Group of IASP: Pain at the Centre, Ayers Rock, Australia, 18-20 September 2008. |
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2008 Conference Publication Efficacy of Pregabalin And Oxycodone in patients with post-herpetic neuralgia or painful diabetic neuropathyZin, Che Suraya, Nissen, Lisa, Smith, Maree, O'Callaghan, James and Moore, Brendan (2008). Efficacy of Pregabalin And Oxycodone in patients with post-herpetic neuralgia or painful diabetic neuropathy. 28th Annual Scientific Meeting of the Australian Pain Society, Perth Western Australian, 30 March - 2 April 2008. |
