2001 Journal Article Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronideWright, AWE, Mather, LE and Smith, MT (2001). Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sciences, 69 (4), 409-420. doi: 10.1016/S0024-3205(01)01133-X |
2000 Journal Article Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in ratsRoss, Fraser B., Wallis, Steven C. and Smith, Maree T. (2000). Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats. Pain, 84 (2-3), 421-428. doi: 10.1016/S0304-3959(99)00230-4 |
2000 Conference Publication Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerveRoss, F. B., Saini, K. and Smith, M. T. (2000). Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Journal Article Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti ratNielsen, C. K., Ross, F. B. and Smith, M. T. (2000). Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 (1), 91-99. |
2000 Conference Publication Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neuronesHemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones. Australasian Pharmaceutical Science Association 2000 Annual Conference, Newcastle, Australia, 6 - 8 December, 2000. University of Qld: Australasian Pharmaceutical Science Association. |
2000 Conference Publication Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal mediumHemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Conference Publication Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neuronesHemstapat, K., Smith, D., Monteith, G. R. and Smith, M. T. (2000). Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Conference Publication ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the ratWright, A. W., Mather, L. E. and Smith, M. T. (2000). ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Conference Publication Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti ratNielsen, C., Ross, F. B. and Smith, M. T. (2000). Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Conference Publication Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpawSmith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Journal Article Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in ratsSmith, M. T., Nielsen, C. K., Lim-Fraser, M. Y. C., Wright, A. W. E. and Lau, M. (2000). Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats. Drug Metabolism And Disposition, 28 (2), 236-244. |
2000 Conference Publication Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphineSmith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Conference Publication Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the ratNielsen, C., Ross, F. B. and Smith, M. T. (2000). Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
2000 Journal Article Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolitesSmith, MT (2000). Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites. Clinical and Experimental Pharmacology and Physiology, 27 (7), 524-528. doi: 10.1046/j.1440-1681.2000.03290.x |
2000 Conference Publication Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MSWright, A. W., Punjanon, T. and Smith, M. T. (2000). Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MS. he Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
1999 Journal Article Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronideHalliday, Andrew J., Bartlett, Selena E., Colditz, Paul and Smith, Maree T. (1999). Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide. Life Sciences, 65 (2), 225-236. doi: 10.1016/S0024-3205(99)00239-8 |
1999 Conference Publication Hydromorphone-3-glucuronide (H3G) is a more potent neuro-excitant than morphine-3-glucuronide (M3G) in the ratWright, A.W. and Smith, M. T. (1999). Hydromorphone-3-glucuronide (H3G) is a more potent neuro-excitant than morphine-3-glucuronide (M3G) in the rat. 9th World Congress on Pain, Vienna, Austria, 22 - 27 August, 1999. Seattle, USA: IASP Press. |
1999 Journal Article Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritisKeates, HL, Cramond, T and Smith, MT (1999). Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis. Anesthesia and Analgesia, 89 (2), 409-415. doi: 10.1097/00000539-199908000-00030 |
1999 Conference Publication Opioid analgesic prescribing and use: An audit of analgesic prescribing by general practitioners and the Multidisciplinary Pain Centre at Royal Brisbane HospitalNissen, L. M., Smith, M. T., Tett, S. E., Williams, B. and Cramond, T. R. (1999). Opioid analgesic prescribing and use: An audit of analgesic prescribing by general practitioners and the Multidisciplinary Pain Centre at Royal Brisbane Hospital. Society of Hospital Pharmacists of Australia 24th Federal Conference, Perth, W.A., 25 - 28 November, 1999. Melbourne, Australia: Society of Hospital Pharmacists of Australia. |
1999 Journal Article Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritisKeates, Helen L., Cramond, Teresa and Smith, Maree T. (1999). Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis. Anesthesia and Analgesia, 89 (2), 409-415. |