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2001

Conference Publication

Pharmacological studies to define the mechanism mediating the neuro-excitatory side-effects of morphine-3-glucuronide (M3G).

Hemstapat, K., Monteith, G. R. and Smith, M. T. (2001). Pharmacological studies to define the mechanism mediating the neuro-excitatory side-effects of morphine-3-glucuronide (M3G).. Australian Society for Medical Research 40th National Scientific Conference, 2001, Surfers Paradise, 24-27 Nov. 2001. Sydney, Aust.: Australian Society for Medical Research.

Pharmacological studies to define the mechanism mediating the neuro-excitatory side-effects of morphine-3-glucuronide (M3G).

2001

Conference Publication

Influence of oestradiol pretreatment of adult male rats on levels of antinociception evoked by chronically infused intravenous morphine

Le, L., Chmura, P., Mather, L. E. and Smith, M. T. (2001). Influence of oestradiol pretreatment of adult male rats on levels of antinociception evoked by chronically infused intravenous morphine. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press.

Influence of oestradiol pretreatment of adult male rats on levels of antinociception evoked by chronically infused intravenous morphine

2001

Conference Publication

M3G's neuro-excitatory side-effects are mediated pre-synaptically: Mechanistic studies implicating dynorphin A.

Hemstapat, K., Monteith, G. R. and Smith, M. T. (2001). M3G's neuro-excitatory side-effects are mediated pre-synaptically: Mechanistic studies implicating dynorphin A.. Annual Scientific Meeting of ASCEPT 2001, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press.

M3G's neuro-excitatory side-effects are mediated pre-synaptically: Mechanistic studies implicating dynorphin A.

2001

Conference Publication

Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysate

Wells, J. A., Punjanon, T., Wright, A. W. and Smith, M. T. (2001). Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysate. Annual Scientific Meeting of ASCEPT 2001, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press.

Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysate

2001

Conference Publication

Follow-up audit of analgesic prescribing and use at the Multidisciplinary Pain Centre at Royal Brisbane Hospital: Temporal changes in anticonvulsant prescribing from 1999 to 2000

Nissen, L., Mattiazzi, A., Smith, M. T., Moore, B., Williams, B. and Cramond, T. R. (2001). Follow-up audit of analgesic prescribing and use at the Multidisciplinary Pain Centre at Royal Brisbane Hospital: Temporal changes in anticonvulsant prescribing from 1999 to 2000. 22nd Annual Scientific Meeting of Australian Pain Society 2001, Cairns, Qld, 8 - 12 April, 2001. Melbourne: Australian Pain Society.

Follow-up audit of analgesic prescribing and use at the Multidisciplinary Pain Centre at Royal Brisbane Hospital: Temporal changes in anticonvulsant prescribing from 1999 to 2000

2001

Conference Publication

Temporal changes in the potency of subcutaneous oxycodone relative to morphine for the alleviation of tactile allodynia in Dark Agouti Rats with diabetes secondary to streptozotocin injection

Smith, M. T., Ross, F. B., Lotfipour, S. and Saini, K. (2001). Temporal changes in the potency of subcutaneous oxycodone relative to morphine for the alleviation of tactile allodynia in Dark Agouti Rats with diabetes secondary to streptozotocin injection. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press.

Temporal changes in the potency of subcutaneous oxycodone relative to morphine for the alleviation of tactile allodynia in Dark Agouti Rats with diabetes secondary to streptozotocin injection

2001

Conference Publication

Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by icv morphine in adult male rats

Punjanon, T., Mather, L. E. and Smith, M. T. (2001). Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by icv morphine in adult male rats. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press.

Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by icv morphine in adult male rats

2001

Journal Article

Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide

Wright, AWE, Mather, LE and Smith, MT (2001). Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sciences, 69 (4), 409-420. doi: 10.1016/S0024-3205(01)01133-X

Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide

2000

Journal Article

Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats

Ross, Fraser B., Wallis, Steven C. and Smith, Maree T. (2000). Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats. Pain, 84 (2-3), 421-428. doi: 10.1016/S0304-3959(99)00230-4

Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats

2000

Conference Publication

Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve

Ross, F. B., Saini, K. and Smith, M. T. (2000). Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve

2000

Journal Article

Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat

Nielsen, C. K., Ross, F. B. and Smith, M. T. (2000). Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 (1), 91-99.

Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat

2000

Conference Publication

Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones

Hemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones. Australasian Pharmaceutical Science Association 2000 Annual Conference, Newcastle, Australia, 6 - 8 December, 2000. University of Qld: Australasian Pharmaceutical Science Association.

Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones

2000

Conference Publication

Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium

Hemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium

2000

Conference Publication

Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones

Hemstapat, K., Smith, D., Monteith, G. R. and Smith, M. T. (2000). Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones

2000

Conference Publication

ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat

Wright, A. W., Mather, L. E. and Smith, M. T. (2000). ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat

2000

Conference Publication

Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat

Nielsen, C., Ross, F. B. and Smith, M. T. (2000). Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat

2000

Conference Publication

Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw

Smith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw

2000

Journal Article

Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats

Smith, M. T., Nielsen, C. K., Lim-Fraser, M. Y. C., Wright, A. W. E. and Lau, M. (2000). Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats. Drug Metabolism And Disposition, 28 (2), 236-244. doi: 10.1016/s0090-9556(24)15133-1

Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats

2000

Conference Publication

Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine

Smith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine

2000

Conference Publication

Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat

Nielsen, C., Ross, F. B. and Smith, M. T. (2000). Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat