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2001 Conference Publication Pharmacological studies to define the mechanism mediating the neuro-excitatory side-effects of morphine-3-glucuronide (M3G).Hemstapat, K., Monteith, G. R. and Smith, M. T. (2001). Pharmacological studies to define the mechanism mediating the neuro-excitatory side-effects of morphine-3-glucuronide (M3G).. Australian Society for Medical Research 40th National Scientific Conference, 2001, Surfers Paradise, 24-27 Nov. 2001. Sydney, Aust.: Australian Society for Medical Research. |
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2001 Conference Publication Influence of oestradiol pretreatment of adult male rats on levels of antinociception evoked by chronically infused intravenous morphineLe, L., Chmura, P., Mather, L. E. and Smith, M. T. (2001). Influence of oestradiol pretreatment of adult male rats on levels of antinociception evoked by chronically infused intravenous morphine. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press. |
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2001 Conference Publication M3G's neuro-excitatory side-effects are mediated pre-synaptically: Mechanistic studies implicating dynorphin A.Hemstapat, K., Monteith, G. R. and Smith, M. T. (2001). M3G's neuro-excitatory side-effects are mediated pre-synaptically: Mechanistic studies implicating dynorphin A.. Annual Scientific Meeting of ASCEPT 2001, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press. |
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2001 Conference Publication Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysateWells, J. A., Punjanon, T., Wright, A. W. and Smith, M. T. (2001). Electrolyte removal is essential for optimizing ESI-MS/MS signal intensity for the quantification of morphine and morphine-3-glucuronide in samples of rat brain microdialysate. Annual Scientific Meeting of ASCEPT 2001, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press. |
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2001 Conference Publication Follow-up audit of analgesic prescribing and use at the Multidisciplinary Pain Centre at Royal Brisbane Hospital: Temporal changes in anticonvulsant prescribing from 1999 to 2000Nissen, L., Mattiazzi, A., Smith, M. T., Moore, B., Williams, B. and Cramond, T. R. (2001). Follow-up audit of analgesic prescribing and use at the Multidisciplinary Pain Centre at Royal Brisbane Hospital: Temporal changes in anticonvulsant prescribing from 1999 to 2000. 22nd Annual Scientific Meeting of Australian Pain Society 2001, Cairns, Qld, 8 - 12 April, 2001. Melbourne: Australian Pain Society. |
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2001 Conference Publication Temporal changes in the potency of subcutaneous oxycodone relative to morphine for the alleviation of tactile allodynia in Dark Agouti Rats with diabetes secondary to streptozotocin injectionSmith, M. T., Ross, F. B., Lotfipour, S. and Saini, K. (2001). Temporal changes in the potency of subcutaneous oxycodone relative to morphine for the alleviation of tactile allodynia in Dark Agouti Rats with diabetes secondary to streptozotocin injection. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press. |
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2001 Conference Publication Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by icv morphine in adult male ratsPunjanon, T., Mather, L. E. and Smith, M. T. (2001). Prolonged oestradiol supplementation does not significantly alter levels of antinociception evoked by icv morphine in adult male rats. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press. |
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2001 Journal Article Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronideWright, AWE, Mather, LE and Smith, MT (2001). Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sciences, 69 (4), 409-420. doi: 10.1016/S0024-3205(01)01133-X |
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2000 Journal Article Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in ratsRoss, Fraser B., Wallis, Steven C. and Smith, Maree T. (2000). Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats. Pain, 84 (2-3), 421-428. doi: 10.1016/S0304-3959(99)00230-4 |
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2000 Conference Publication Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerveRoss, F. B., Saini, K. and Smith, M. T. (2000). Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Journal Article Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti ratNielsen, C. K., Ross, F. B. and Smith, M. T. (2000). Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 (1), 91-99. |
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2000 Conference Publication Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neuronesHemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones. Australasian Pharmaceutical Science Association 2000 Annual Conference, Newcastle, Australia, 6 - 8 December, 2000. University of Qld: Australasian Pharmaceutical Science Association. |
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2000 Conference Publication Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal mediumHemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neuronesHemstapat, K., Smith, D., Monteith, G. R. and Smith, M. T. (2000). Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the ratWright, A. W., Mather, L. E. and Smith, M. T. (2000). ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti ratNielsen, C., Ross, F. B. and Smith, M. T. (2000). Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpawSmith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Journal Article Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in ratsSmith, M. T., Nielsen, C. K., Lim-Fraser, M. Y. C., Wright, A. W. E. and Lau, M. (2000). Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats. Drug Metabolism And Disposition, 28 (2), 236-244. doi: 10.1016/s0090-9556(24)15133-1 |
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2000 Conference Publication Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphineSmith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the ratNielsen, C., Ross, F. B. and Smith, M. T. (2000). Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |