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2001 Journal Article Analgesic tolerance to opioidsSouth, S. M. and Smith, M. T. (2001). Analgesic tolerance to opioids. Pain: Clinical Updates, 9 (5), 1-4. |
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2001 Conference Publication Preliminery investigation of the ability of oxycodone to stimulate agonist-induced internalisation of the m-opioid receptorNielsen, C., Smith, M. T. and Ross, F. B. (2001). Preliminery investigation of the ability of oxycodone to stimulate agonist-induced internalisation of the m-opioid receptor. Annual Scientific Meeting of ASCEPT, Dunedin, New Zealand, 3 - 5 December, 2001. Melbourne, Vic: ASCEPT Press. |
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2001 Conference Publication Oxycodone has a distinctly different pharmacology from morphineSmith, Maree T., Ross, Fraser B., Nielsen, Carsten K. and Saini, Kamal (2001). Oxycodone has a distinctly different pharmacology from morphine. 2nd Asian-Pacific Symposium on Pain Control, Sydney, Australia, 26-28 January, 2001. London, UK: W.B. Saunders. doi: 10.1053/eujp.2001.0301 |
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2001 Conference Publication The neuro-excitatory effects of morphine-3-glucuronide (M3G): Studies of the possible role of non-NMDA mechanisms in cultured embryonic rat hippocampal neurones.Hemstapat, K., Smith, D., Monteith, G. R. and Smith, M. T. (2001). The neuro-excitatory effects of morphine-3-glucuronide (M3G): Studies of the possible role of non-NMDA mechanisms in cultured embryonic rat hippocampal neurones.. 22nd Annual Scientific Meeting of Australian Pain Society, Cairns, Qld, 8-12 April 2001. Melbourne: Australian Pain Society. |
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2001 Conference Publication Evaluation of the neurotoxic effects of morphine-3-glucuronide (M3G) in neuronal cultures.Hemstapat, K., Smith, S. A., Monteith, G. R. and Smith, M. T. (2001). Evaluation of the neurotoxic effects of morphine-3-glucuronide (M3G) in neuronal cultures.. Annual Conference of APSA, Melbourne, 24-27 Nov 2001. Melbourne: APSA. |
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2000 Journal Article Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in ratsRoss, Fraser B., Wallis, Steven C. and Smith, Maree T. (2000). Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats. Pain, 84 (2-3), 421-428. doi: 10.1016/S0304-3959(99)00230-4 |
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2000 Conference Publication Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpawSmith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Journal Article Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in ratsSmith, M. T., Nielsen, C. K., Lim-Fraser, M. Y. C., Wright, A. W. E. and Lau, M. (2000). Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats. Drug Metabolism And Disposition, 28 (2), 236-244. doi: 10.1016/s0090-9556(24)15133-1 |
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2000 Conference Publication Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphineSmith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the ratNielsen, C., Ross, F. B. and Smith, M. T. (2000). Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Journal Article Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolitesSmith, MT (2000). Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites. Clinical and Experimental Pharmacology and Physiology, 27 (7), 524-528. doi: 10.1046/j.1440-1681.2000.03290.x |
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2000 Conference Publication Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MSWright, A. W., Punjanon, T. and Smith, M. T. (2000). Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MS. he Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerveRoss, F. B., Saini, K. and Smith, M. T. (2000). Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Journal Article Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti ratNielsen, C. K., Ross, F. B. and Smith, M. T. (2000). Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 (1), 91-99. |
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2000 Conference Publication Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neuronesHemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones. Australasian Pharmaceutical Science Association 2000 Annual Conference, Newcastle, Australia, 6 - 8 December, 2000. University of Qld: Australasian Pharmaceutical Science Association. |
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2000 Conference Publication Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal mediumHemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neuronesHemstapat, K., Smith, D., Monteith, G. R. and Smith, M. T. (2000). Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the ratWright, A. W., Mather, L. E. and Smith, M. T. (2000). ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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2000 Conference Publication Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti ratNielsen, C., Ross, F. B. and Smith, M. T. (2000). Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications. |
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1999 Journal Article Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronideHalliday, Andrew J., Bartlett, Selena E., Colditz, Paul and Smith, Maree T. (1999). Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide. Life Sciences, 65 (2), 225-236. doi: 10.1016/S0024-3205(99)00239-8 |
