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2001

Journal Article

Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide

Wright, AWE, Mather, LE and Smith, MT (2001). Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sciences, 69 (4), 409-420. doi: 10.1016/S0024-3205(01)01133-X

Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide

2000

Journal Article

Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats

Ross, Fraser B., Wallis, Steven C. and Smith, Maree T. (2000). Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats. Pain, 84 (2-3), 421-428. doi: 10.1016/S0304-3959(99)00230-4

Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats

2000

Conference Publication

Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve

Ross, F. B., Saini, K. and Smith, M. T. (2000). Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Differential potency of subcutaneous morphine and oxycodone for the relief of mechanical allodynia in dark agouti rats with a chronic constriction injury (CCI) of the sciatic nerve

2000

Journal Article

Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat

Nielsen, C. K., Ross, F. B. and Smith, M. T. (2000). Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 (1), 91-99.

Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat

2000

Conference Publication

Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones

Hemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones. Australasian Pharmaceutical Science Association 2000 Annual Conference, Newcastle, Australia, 6 - 8 December, 2000. University of Qld: Australasian Pharmaceutical Science Association.

Morphine-3-glucuronide (M3G) evoked increases in [Ca2+]cyt oscillations in cultured rat embryonic hippocampal neurones

2000

Conference Publication

Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium

Hemstapat, K., Monteith, G. R. and Smith, M. T. (2000). Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Spontaneous oscillations in neuronal cytosolic free Ca2+ ([Ca2+]cyt ) in rat cultured embryonic hippocampal neurons maintained in serum-free neurobasal medium

2000

Conference Publication

Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones

Hemstapat, K., Smith, D., Monteith, G. R. and Smith, M. T. (2000). Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Elucidation of the mechanism underlying the neuro-excitatory effects of morphine-3-glucoronide (M3G): Studies in rat embryonic hippocampal neurones

2000

Conference Publication

ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat

Wright, A. W., Mather, L. E. and Smith, M. T. (2000). ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

ICV hydromorphone-3-glucuronide (H3G) elicits neuro-excitation in the rat

2000

Conference Publication

Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat

Nielsen, C., Ross, F. B. and Smith, M. T. (2000). Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3-6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Absence of antinociceptive cross-tolerance between supraspinal oxycodone and intravenous morphine in the dark agouti rat

2000

Conference Publication

Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw

Smith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Antinociceptive efficacy of intrathecal AM336 for the relief of adjuvant-induced chronic inflammatory pain in the rat hindpaw

2000

Journal Article

Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats

Smith, M. T., Nielsen, C. K., Lim-Fraser, M. Y. C., Wright, A. W. E. and Lau, M. (2000). Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats. Drug Metabolism And Disposition, 28 (2), 236-244.

Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats

2000

Conference Publication

Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine

Smith, M. T., Ross, F. B., Lewis, R., Kurek, J. and Cabot, P. J. (2000). Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine. The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Lack of cross-tolerance between intrathecal AM336 and intravenous morphine in contrast to the marked cross-tolerance between ziconotide and morphine

2000

Conference Publication

Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat

Nielsen, C., Ross, F. B. and Smith, M. T. (2000). Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat. Joint Meeting of ASCEPT and the British Pharmacological Society, Melbourne, Australia, 26 - 28 April, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Incomplete and assymetric antinociceptive cross-tolerance between oxycodone and morphine in the rat

2000

Journal Article

Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites

Smith, MT (2000). Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites. Clinical and Experimental Pharmacology and Physiology, 27 (7), 524-528. doi: 10.1046/j.1440-1681.2000.03290.x

Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites

2000

Conference Publication

Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MS

Wright, A. W., Punjanon, T. and Smith, M. T. (2000). Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MS. he Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists Annual Scientific Meeting, Newcastle, Australia, 3 - 6 December, 2000. Melbourne, Vic.: Blackwell Scientific Publications.

Determination of morphine, M3G, M6G, oxycodone and their N-demethylated metabolites in biological fluids, using HPLC-MS/MS

1999

Journal Article

Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide

Halliday, Andrew J., Bartlett, Selena E., Colditz, Paul and Smith, Maree T. (1999). Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide. Life Sciences, 65 (2), 225-236. doi: 10.1016/S0024-3205(99)00239-8

Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide

1999

Conference Publication

Hydromorphone-3-glucuronide (H3G) is a more potent neuro-excitant than morphine-3-glucuronide (M3G) in the rat

Wright, A.W. and Smith, M. T. (1999). Hydromorphone-3-glucuronide (H3G) is a more potent neuro-excitant than morphine-3-glucuronide (M3G) in the rat. 9th World Congress on Pain, Vienna, Austria, 22 - 27 August, 1999. Seattle, USA: IASP Press.

Hydromorphone-3-glucuronide (H3G) is a more potent neuro-excitant than morphine-3-glucuronide (M3G) in the rat

1999

Journal Article

Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis

Keates, HL, Cramond, T and Smith, MT (1999). Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis. Anesthesia and Analgesia, 89 (2), 409-415. doi: 10.1097/00000539-199908000-00030

Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis

1999

Conference Publication

Opioid analgesic prescribing and use: An audit of analgesic prescribing by general practitioners and the Multidisciplinary Pain Centre at Royal Brisbane Hospital

Nissen, L. M., Smith, M. T., Tett, S. E., Williams, B. and Cramond, T. R. (1999). Opioid analgesic prescribing and use: An audit of analgesic prescribing by general practitioners and the Multidisciplinary Pain Centre at Royal Brisbane Hospital. Society of Hospital Pharmacists of Australia 24th Federal Conference, Perth, W.A., 25 - 28 November, 1999. Melbourne, Australia: Society of Hospital Pharmacists of Australia.

Opioid analgesic prescribing and use: An audit of analgesic prescribing by general practitioners and the Multidisciplinary Pain Centre at Royal Brisbane Hospital

1999

Journal Article

Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis

Keates, Helen L., Cramond, Teresa and Smith, Maree T. (1999). Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis. Anesthesia and Analgesia, 89 (2), 409-415.

Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis