|
2012 Conference Publication Role of HER3 in brain metastases from primary breast cancerSaunus, Jodi M., Da Silva, Leonard, Momeny, Majid, Morrison, Brian, Lane, Annette, Smart, Chanel, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia, Simpson, Peter T. and Lakhani, Sunil R. (2012). Role of HER3 in brain metastases from primary breast cancer. 24th Lorne Cancer Conference, Lorne, VIC, Australia, 9-12 February 2012. |
|
2011 Journal Article ATM protein kinase: The linchpin of cellular defenses to stressBhatti, Shahzad, Kozlov, Sergei, Farooqi, Ammad Ahmad, Naqi, Ali, Lavin, Martin and Khanna, Kum Kum (2011). ATM protein kinase: The linchpin of cellular defenses to stress. Cellular and Molecular Life Sciences, 68 (18), 2977-3006. doi: 10.1007/s00018-011-0683-9 |
|
2011 Journal Article Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neuronsJung, Cha-Gyun, Uhm, Kyung-Ok, Miura, Yutaka, Hosono, Takashi, Horike, Hirofumi, Khanna, Kum Kum, Kim, Mi-Jeong and Michikawa, Makoto (2011). Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons. Molecular Neurodegeneration, 6 (47) 47, 1-14. doi: 10.1186/1750-1326-6-47 |
|
2011 Journal Article Rare variants in the ATM gene and risk of breast cancerGoldgar, David E., Healey, Sue, Dowty, James G., Da Silva, Leonard, Chen, Xiaoqing, Spurdle, Amanda B., Terry, Mary B., Daly, Mary J., Buys, Saundra M., Southey, Melissa C., Andrulis, Irene, John, Esther M., Breast Cancer Family Registry, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Khanna, Kum K., Hopper, John L., Oefner, Peter J., Lakhani, Sunil and Chenevix-Trench, Georgia (2011). Rare variants in the ATM gene and risk of breast cancer. Breast Cancer Research, 13 (4) R73, R73-1-R73-9. doi: 10.1186/bcr2919 |
|
2011 Journal Article hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activityRichard, Derek J., Cubeddu, Liza, Urquhart, Aaron J., Bain, Amanda, Bolderson, Emma, Menon, Dinoop, White, Malcolm F. and Khanna, Kum Kum (2011). hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity. Nucleic Acids Research, 39 (9), 3643-3651. doi: 10.1093/nar/gkq1340 |
|
2011 Journal Article Breast cancer stem cells: Treatment resistance and therapeutic opportunitiesAL-Ejeh, Fares, Smart, Chanel E., Morrison, Brian J., Chenevix-Trench, Georgia, Lopez, J. Alejandro, Lakhani, Sunil R., Brown, Michael P. and Khanna, Kum Kum (2011). Breast cancer stem cells: Treatment resistance and therapeutic opportunities. Carcinogenesis, 32 (5), 650-658. doi: 10.1093/carcin/bgr028 |
|
2011 Journal Article A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in miceYoungson, N. A., Vickaryous, N., van der Horst, A., Epp, T., Harten, S., Fleming, J. S., Khanna, K. K., de Kretser, D. M. and Whitelaw, Emma (2011). A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice. Mammalian Genome, 22 (3-4), 235-248. doi: 10.1007/s00335-011-9317-7 |
|
2011 Journal Article hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complexRichard, Derek J., Savage, Kienan, Bolderson, Emma, Cubeddu, Liza, So, Sairei, Ghita, Mihaela, Chen, David J., White, Malcolm F., Richard, Kerry, Prise, Kevin M., Schettino, Giuseppe and Khanna, Kum Kum (2011). hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex. Nucleic Acids Research, 39 (5), 1692-1702. doi: 10.1093/nar/gkq1098 |
|
2011 Journal Article Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challengesSimpson, Peter T., Vargas, Ana Christina, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2011). Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges. Human Pathology, 42 (2), 153-165. doi: 10.1016/j.humpath.2010.07.008 |
|
2011 Journal Article Mutation analysis of RAD51L1 (RAD51B/REC2) in multiple-case, non-BRCA1/2 breast cancer familiesJohnson, Julie, Healey, Sue, Khanna, Kum Kum, kConFab and Chenevix-Trench, Georgia (2011). Mutation analysis of RAD51L1 (RAD51B/REC2) in multiple-case, non-BRCA1/2 breast cancer families. Breast Cancer Research and Treatment, 129 (1), 255-263. doi: 10.1007/s10549-011-1539-6 |
|
2010 Journal Article Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humansSchoenmakers, Erik, Agostini, Maura, Mitchell, Catherine, Schoenmakers, Nadia, Papp, Laura, Rajanayagam, Odelia, Padidela, Raja, Ceron-Gutierrez, Lourdes, Doffinger, Rainer, Prevosto, Claudia, Luan, Jian'an, Montano, Sergio, Lu, Jun, Castanet, Mireille, Clemons, Nick, Groeneveld, Matthijs, Castets, Perrine, Karbaschi, Mahsa, Aitken, Sri, Dixon, Adrian, Williams, Jane, Campi, Irene, Blount, Margaret, Burton, Hannah, Muntoni, Francesco, O'Donovan, Dominic, Dean, Andrew, Warren, Anne, Brierley, Charlotte ... Chatterjee, Krishna (2010). Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. Journal of Clinical Investigation, 120 (12), 4220-4235. doi: 10.1172/JCI43653 |
|
2010 Journal Article Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomesAl-Ejeh, F., Kumar, R., Wiegmans, A., Lakhani, S.R., Brown, M.P. and Khanna, K.K. (2010). Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene, 29 (46), 6085-6098. doi: 10.1038/onc.2010.407 |
|
2010 Journal Article The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stressKim, TS, Kawaguchi, M, Suzuki, M, Jung, CG, Asai, K, Shibamoto, Y, Lavin, MF, Khanna, KK and Miura, Y (2010). The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. DMM Disease Models and Mechanisms, 3 (11-12), 752-762. doi: 10.1242/dmm.004689 |
|
2010 Journal Article A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activationHinz, Michael, Stilmann, Michael, Arslan, Seda Çöl, Khanna, Kum Kum, Dittmar, Gunnar and Scheidereit, Claus (2010). A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. Molecular Cell, 40 (1), 63-74. doi: 10.1016/j.molcel.2010.09.008 |
|
2010 Journal Article Subtypes of familial breast tumours revealed by expression and copy number profilingWaddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010). Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 (3), 661-677. doi: 10.1007/s10549-009-0653-1 |
|
2010 Journal Article Novel single stranded DNA binding proteins crucial for the DNA damage responseCubeddu, L., Richard, D. J., White, M. F. and Khanna, K. K. (2010). Novel single stranded DNA binding proteins crucial for the DNA damage response. The FEBS Journal, 277 (Supp. 1), 193-193. doi: 10.1111/j.1742-4658.2010.07680.x |
|
2010 Journal Article Centrobin regulates the assembly of functional mitotic spindlesJeffery, J. M., Urquhart, A. J., Subramaniam, V. N., Parton, R.G. and Khanna, K.K. (2010). Centrobin regulates the assembly of functional mitotic spindles. Oncogene, 29 (18), 2649-2658. doi: 10.1038/onc.2010.37 |
|
2010 Journal Article Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaksBolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J., Boucher, Didier, Kumar, Rakesh, Pandita, Tej K., Burma, Sandeep and Khanna, Kum Kum (2010). Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks. Nucleic Acids Research, 38 (6) gkp1164, 1821-1831. doi: 10.1093/nar/gkp1164 |
|
2010 Journal Article Selenium and selenoproteins in health and diseasePapp, Laura V., Holmgren, Arne and Khanna, Kum Kum (2010). Selenium and selenoproteins in health and disease. Antioxidants and Redox Signaling, 12 (7), 793-795. doi: 10.1089/ars.2009.2973 |
|
2010 Journal Article SECIS-binding protein 2 promotes cell survival by protecting against oxidative stressPapp, Laura V., Lu, Jun, Bolderson, Emma, Boucher, Didier, Singh, Ravindra, Holmgren, Arne and Khanna, Kum Kum (2010). SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress. Antioxidants and Redox Signaling, 12 (7), 797-808. doi: 10.1089/ars.2009.2913 |
