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2010 Journal Article DNA methylome of familial breast cancer identifies distinct profiles defined by mutation statusFlanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008 |
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2010 Journal Article Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?Lakhani, Sunil R., Khanna, Kum K. and Chenevix-Trench, Georgia (2010). Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?. Breast Cancer Research, 12 (2) 104, 104-1-104-2. doi: 10.1186/bcr2483 |
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2010 Journal Article HER3 and downstream pathways are involved in colonization of brain metastases from breast cancerDa Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603 |
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2009 Journal Article Cep55 stabilization is required for normal execution of cytokinesisArmando van der Horst, Jacinta Simmons and Kum Kum Khanna (2009). Cep55 stabilization is required for normal execution of cytokinesis. Cell Cycle, 8 (22), 3742-3749. doi: 10.4161/cc.8.22.10047 |
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2009 Journal Article Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break RepairEmma Bolderson, Derek J. Richard, Bin-Bing S. Zhou and Kum Kum Khanna (2009). Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair. Clinical Cancer Research, 15 (20), 6314-6320. doi: 10.1158/1078-0432.CCR-09-0096 |
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2009 Journal Article Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X)Caterina Di Cosmo, Neil McLellan, Xiao-Hui Liao, Kum Kum Khanna, Roy E. Weiss, Laura Papp and Samuel Refetoff (2009). Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X). Journal of Clinical Endocrinology and Metabolism, 94 (10), 4003-4009. doi: 10.1210/jc.2009-0686 |
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2009 Journal Article INTS3 controls the hSSB1-mediated DNA damage responseJeffrey R. Skaar, Derek J. Richard, Anita Saraf, Alfredo Toschi, Emma Bolderson, Laurence Florens, Michael P. Washburn, Kum Kum Khanna and Michele Pagano (2009). INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology, 187 (1), 25-32. doi: 10.1083/jcb.200907026 |
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2009 Journal Article The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55Armando van der Horst and Kum Kum Khanna (2009). The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55. Cancer Research, 69 (16), 6651-6659. doi: 10.1158/0008-5472.CAN-09-0825 |
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2009 Journal Article hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage ResponseYongjiang Li, Emma Bolderson, Rakesh Kumar, Parameswary A. Muniandy, Yutong Xue, Derek J. Richard, Michael Seidman, Tej K. Pandita, Kum Kum Khanna and Weidong Wang (2009). hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response. Journal of Biological Chemistry, 284 (35), 23525-23531.. doi: 10.1074/jbc.C109.039586 |
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2009 Journal Article Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repairArun Gupta, Qin Yang, Raj K. Pandita, Clayton R. Hunt, Tao Xiang, Sandeep Misri, Sicong Zeng, Julia Pagan, Jessie Jeffery, Janusz Puc, Rakesh Kumar, Zhihui Feng, Simon N. Powell, Audesh Bhat, Tomoko Yaguchi, Renu Wadhwa, Sunil C. Kaul, Ramon Parsons, Kum Kum Khanna and Tej K. Pandita (2009). Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle, 8 (14), 2198-2210. doi: 10.4161/cc.8.14.8947 |
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2009 Journal Article Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysisRichard, Derek J., Bolderson, Emma and Khanna, Kum Kum (2009). Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology, 44 (2-3), 98-116. doi: 10.1080/10409230902849180 |
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2009 Journal Article Involvement of Exo1b in DNA damage-induced apoptosisEmma Bolderson, Derek J. Richard, Winfried Edelmann and Kum Kum Khanna (2009). Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research, 37 (10), 3452-3463. doi: 10.1093/nar/gkp194 |
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2009 Journal Article The actin-binding and bundling protein, EPLIN, is required for cytokinesisMegan Chircop, Vanessa Oakes, Mark E. Graham, Maggie P.C. Ma, Charlotte M. Smith, Phillip J. Robinson and Kum Kum Khanna (2009). The actin-binding and bundling protein, EPLIN, is required for cytokinesis. Cell Cycle, 8 (5), 757-764. doi: 10.4161/cc.8.5.7878 |
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2008 Journal Article Functional characterization of alternatively spliced human SECISBP2 transcript variantsPapp, Laura V., Wang, Junning, Kennedy, Derek, Boucher, Didier, Zhang, Yan, Gladysheve, Vadim N., Sing, Ravindra N. and Khanna, Kum Kum (2008). Functional characterization of alternatively spliced human SECISBP2 transcript variants. Nucleic Acids Research, 36 (22), 7192-7206. doi: 10.1093/nar/gkn829 |
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2008 Journal Article Correction: BCoR-L1 variation and breast cancerLose, Felicity, Arnold, Jeremy, Young, David B., Brown, Carolyn J., Mann, Graham J., Pupo, Gulietta M., Khanna, Kum K., Chenevix-Trench, Georgia and Spurdle, Amanda B. (2008). Correction: BCoR-L1 variation and breast cancer. Breast Cancer Research, 10 (5) 406. doi: 10.1186/bcr2153 |
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2008 Journal Article Single-stranded DNA-binding protein hSSB1 is critical for genomic stabilityRichard, Derek J., Bolderson, Emma, Cubeddu, Liza, Wadsworth, Ross I. M., Savage, Kienan, Sharma, Girdhar G., Nicolette, Matthew L., Tsvetanov, Sergie, McIlwraith, Michael J., Pandita, Raj K., Takeda, Shunichi, Hay, Ronald T., Gautier, Jean, West, Stephen C., Paull, Tanya T., Pandita, Tej K., White, Malcolm F. and Khanna, Kum Kum (2008). Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature, 453 (7195), 677-681. doi: 10.1038/nature06883 |
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2007 Journal Article Mutation analysis of five candidate genes in familial breast cancerMarsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007). Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 (3), 377-389. doi: 10.1007/s10549-006-9461-z |
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2007 Journal Article A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBPPagan, Julia K., Arnold, Jeremy, Hanchard, Kim J., Kumar, Raman, Bruno, Tiziana, Jones, Mathew J.K., Richard, Derek J., Forrest, Alistair, Spurdle, Amanda, Verdin, Eric, Crossley, Merlin, Fanciulli, Maurizio, Chenevix-Trench, Georgia, Young, David B. and Khanna, Kum Kum (2007). A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. Journal of Biological Chemistry, 282 (20), 15248-15257. doi: 10.1074/jbc.M700246200 |
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2007 Journal Article Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancerPylkas, K, Tommiska, J, Syrjakoski, K, Kere, J, Gatei, M, Waddell, N, Allinen, M, Karppinen, SM, Rapakko, K, Kaariainen, H, Aittomaki, K, Blomqvist, C, Mustonen, A, Holli, K, Khanna, KK, Kallioniemi, OP, Nevanlinna, H and Winqvist, R (2007). Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer. Carcinogenesis, 28 (5), 1040-1045. doi: 10.1093/carcin/bgl237 |
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2007 Journal Article From selenium to selenoproteins: Synthesis, identity, and their role in human healthPapp, Laura Vanda, Lu, Jun, Holmgren, Arne and Khanna, Kum Kum (2007). From selenium to selenoproteins: Synthesis, identity, and their role in human health. Antioxidants & Redox Signaling, 9 (7), 775-806. doi: 10.1089/ars.2007.1528 |
