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2000 Journal Article Caffeine abolishes the mammalian G2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activityZhou, B., Chaturvedi, P.S., Spring, K., Scott, S. P., Johanson, R. A., Mishra, R.G., Mattern, M. R., Winkler, J. D. and Khanna, K. K. (2000). Caffeine abolishes the mammalian G2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. Journal of Biological Chemistry, 275 (14), 10342-10348. doi: 10.1074/jbc.275.14.10342 |
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2000 Journal Article Role for ATM in DNA damage-induced phosphorylation of BRCA1Gatei, M., Scott, S. P., Filippovitch, I., Soronika, N., Lavin, M. F., Weber, B. and Khanna, K. (2000). Role for ATM in DNA damage-induced phosphorylation of BRCA1. Cancer Research, 60 (12), 3299-3304. |
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2000 Journal Article Defective radiation signal transduction in ataxia-telangiectasia cellsYan, J., Khanna, K. K. and Lavin, M. F. (2000). Defective radiation signal transduction in ataxia-telangiectasia cells. International Journal of Radiation Biology, 76 (8), 1025-1035. doi: 10.1080/09553000050111497 |
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2000 Journal Article Functional characterisation of cultured cells derived from an intraepidermal carcinoma of the skin (IEC-1)Dicker, A., Serewko, M. S., Dahler, A. L., Khanna, K. K., Kaur, P., Li, A., Strutton, G. and Saunders, N. A. (2000). Functional characterisation of cultured cells derived from an intraepidermal carcinoma of the skin (IEC-1). Experimental Cell Research, 258 (2), 352-360. doi: 10.1006/excr.2000.4944 |
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2000 Journal Article p73 is up-regulated in a subset of hepatocellular carcinomasHerath, NI, Kew, MC, Whitehall, VLJ, Walsh, MD, Jass, JR, Khanna, KK, Young, J, Powell, LW, Leggett, BA and Macdonald, GA (2000). p73 is up-regulated in a subset of hepatocellular carcinomas. Hepatology, 31 (3), 601-605. doi: 10.1002/hep.510310309 |
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1999 Journal Article ATM is upregulated during the mitogenic response in peripheral blood mononuclear cellsFukao, Toshiyuki, Kaneko, Hideo, Birrell, Geoff, Gatei, Magtouf, Tashita, Hideaki, Yoshida, Toko, Cross, Simone, Kedar, Padmini, Watters, Dianne, Khanna, Kum Kum, Misko, Ihor, Kondo, Naomi and Lavin, Martin F. (1999). ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells. Blood, 94 (6), 1998-2006. doi: 10.1182/blood.v94.6.1998.418k01_1998_2006 |
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1999 Journal Article Frequent loss of heterozygosity at 1p36 in ovarian adenocarcinomas but the gene encoding p73 is unlikely to be the targetImyanitov, Evgeny N., Birrell, Geoff W., Filippovich, Igor, Sorokina, Natasha, Arnold, Jeremy, Mould, Michelle A., Wright, Kim, Walsh, Michael, Mok, Samuel C ., Lavin, Martin F., Chenevix-Trench, Georgia and Khanna, Kum Kum (1999). Frequent loss of heterozygosity at 1p36 in ovarian adenocarcinomas but the gene encoding p73 is unlikely to be the target. Oncogene, 18 (32), 4640-4642. doi: 10.1038/sj.onc.1202863 |
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1999 Journal Article CHK1 complements the G2/M Chek point defect and radio sensitivityof ataxia-telangiectasiaChen, P., Gatei, M., O'Connell, M. J., Khanna, K. K., Bugg, S. J., Hogg, A., Scott, S. P., Hobson, K. and Lavin, M. F. (1999). CHK1 complements the G2/M Chek point defect and radio sensitivityof ataxia-telangiectasia. Oncogene, 18 (1), 249-256. doi: 10.1038/sj.onc.1202257 |
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1999 Journal Article ATM: The protein encoded by the gene mutilated in the radio sensitive syndrome ataxia - telangiectasiaLavin, M. F. and Khanna, K. K. (1999). ATM: The protein encoded by the gene mutilated in the radio sensitive syndrome ataxia - telangiectasia. International Journal of Radiation Biology, 75 (10), 1201-1214. |
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1998 Journal Article Calpain activation is upstream of caspases in radiation-induced apoptosisWaterhouse, Nigel J., Finucane, Debra M., Green, Douglas R., Elce, John S., Kumar, Sharad, Alnemri, Emad S., Litwack, Gerald, Khanna, Kumkum, Lavin, Martin F. and Watters, Dianne J. (1998). Calpain activation is upstream of caspases in radiation-induced apoptosis. Cell Death and Differentiation, 5 (12), 1051-1061. doi: 10.1038/sj.cdd.4400425 |
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1998 Journal Article An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cellsZhang, Ning, Chen, Phil, Gatei, Magtouf, Scott, Shaun, Khanna, Kum Kum and Lavin, Martin F. (1998). An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells. Oncogene, 17 (7), 811-818. doi: 10.1038/sj.onc.1202007 |
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1998 Journal Article Cloning and expression of the ataxia-telangiectasia gene in baculovirusScott, SP, Zhang, N, Khanna, KK, Khromykh, A, Hobson, K, Watters, D and Lavin, MF (1998). Cloning and expression of the ataxia-telangiectasia gene in baculovirus. Biochemical and Biophysical Research Communications, 245 (1), 144-148. doi: 10.1006/bbrc.1998.8137 |
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1998 Journal Article ATM associates with and phosphorylates p53: Mapping the region of interactionKhanna K.K., Keating K.E., Kozlov S., Scott S., Gatei M., Hobson K., Taya Y., Gabrielli B., Chan D., Lees-Miller S.P. and Lavin M.F. (1998). ATM associates with and phosphorylates p53: Mapping the region of interaction. Nature Genetics, 20 (4), 398-400. doi: 10.1038/3882 |
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1997 Journal Article Interaction between ATM protein and c-Abl in response to DNA damageShafman, T, Khanna, KK, Kedar, P, Spring, K, Kozlov, S, Yen, T, Hobson, K, Gatei, M, Zhang, N, Watters, D, Egerton, M, Shiloh, Y, Kharbanda, S, Kufe, D and Lavin, MF (1997). Interaction between ATM protein and c-Abl in response to DNA damage. Nature, 387 (6632), 520-523. doi: 10.1038/387520a0 |
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1997 Journal Article Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal formsWatters, D, Khanna, KK, Beamish, H, Birrell, G, Spring, K, Kedar, P, Gatei, M, Stenzel, D, Hobson, K, Kozlov, S, Zhang, N, Farrell, A, Ramsay, J, Gatti, R and Lavin, M (1997). Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene, 14 (16), 1911-1921. doi: 10.1038/sj.onc.1201037 |
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1997 Journal Article Defective signaling through the B cell antigen receptor in Epstein-Barr virus-transformed ataxia-telangiectasia cellsKhanna, KK, Yan, J, Watters, D, Hobson, K, Beamish, H, Spring, K, Shiloh, Y, Gatti, RA and Lavin, MF (1997). Defective signaling through the B cell antigen receptor in Epstein-Barr virus-transformed ataxia-telangiectasia cells. Journal of Biological Chemistry, 272 (14), 9489-9495. doi: 10.1074/jbc.272.14.9489 |
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1997 Journal Article Isolation of full-length ATM cDNA and correction of the ataxia- telangiectasia cellular phenotypeZhang, N., Chen, P., Khanna, K.K., Scott, S., Gatei, M., Kozlov, S., Watters, D., Spring, K., Yen, T. and Lavin, M.F. (1997). Isolation of full-length ATM cDNA and correction of the ataxia- telangiectasia cellular phenotype. Proceedings of the National Academy of Sciences of the United States of America, 94 (15), 8021-8026. doi: 10.1073/pnas.94.15.8021 |
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1996 Journal Article Induction of inositol 1,4,5 trisphosphate receptor genes by ionizing radiationYan, J, Khanna, KK and Lavin, MF (1996). Induction of inositol 1,4,5 trisphosphate receptor genes by ionizing radiation. International Journal of Radiation Biology, 69 (5), 539-546. doi: 10.1080/095530096145544 |
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1996 Journal Article Genetic complementation of radiation response by 3′ untranslated regions (UTR) of RNAChen, P., Girjes, A. A., Hobson, K., Beamish, H., Khanna, K. K., Farrell, A., Gatei, M., Teale, B., Buchwald, M., Legerski, R. and Lavin, M. F. (1996). Genetic complementation of radiation response by 3′ untranslated regions (UTR) of RNA. International Journal of Radiation Biology, 69 (3), 385-395. doi: 10.1080/095530096145940 |
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1995 Journal Article Nature of G1/s cell-cycle checkpoint defect in ataxia-telangiectasiaKhanna, KK, Beamish, H, Yan, J, Hobson, K, Williams, R, Dunn, I and Lavin, MF (1995). Nature of G1/s cell-cycle checkpoint defect in ataxia-telangiectasia. Oncogene, 11 (4), 609-618. |
