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2007 Journal Article BCoR-L1 variation and breast cancerLose, Felicity, Arnold, Jeremy, Young, David B., Brown, Carolyn J., Mann, Graham J., Pupo, Gulietta M., Khanna, Kum Kum, Chenevix-Trench, Georgia and Spurdle, Amanda B. (2007). BCoR-L1 variation and breast cancer. Breast Cancer Research, 9 (4) R54, 1-12. doi: 10.1186/bcr1759 |
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2006 Journal Article Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profilingWaddell, Nic, Jonnalagadda, Jyoti, Marsh, Anna, Grist, Scott, Jenkins, Mark, Hobson, Karen, Taylor, Malcolm, Lindeman, Geoff J., Tavtigian, Sean V., Suthers, Graeme, Goldgar, David, Oefner, Peter J., kConFab Investigators, Taylor, Darrin, Grimmond, Sean, Khanna, Kum Kum and Chenevix-Trench, Georgia (2006). Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling. Genes Chromosomes and Cancer, 45 (12), 1169-1181. doi: 10.1002/gcc.20381 |
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2006 Journal Article Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpointBruno, Tiziana, De Nicola, Francesca, Iezzi, Simona, Lecis, Daniele, D'Angelo, Carmen, Di Padova, Monica, Corbi, Nicoletta, Dimiziani, Leopoldo, Zannini, Laura, Jekimovs, Christian, Scarsella, Marco, Porrello, Alessandro, Chersi, Alberto, Crescenzi, Marco, Leonetti, Carlo, Khanna, Kum Kum, Soddu, Silvia, Floridi, Aristide, Passananti, Claudio, Domenico Delia and Fanciulli, Maurizio (2006). Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint. Cancer Cell, 10 (6), 473-486. doi: 10.1016/j.ccr.2006.10.012 |
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2006 Journal Article EDD mediates DNA damage-induced activation of CHK2Henderson, Michelle J., Munoz, Marcia A, Saunders, Darren N., Clancy, Jennifer L., Russell, Amanda J., Williams, Brandi, Pappin, Darryl, Khanna, Kum Kum, Jackson, Stephen P., Sutherland, Robert L. and Watts, Colin K. W. (2006). EDD mediates DNA damage-induced activation of CHK2. Journal of Biological Chemistry, 281 (52), 39990-40000. doi: 10.1074/jbc.M602818200 |
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2006 Journal Article Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancersDeans, Andrew J., Khanna, Kum Kum, McNees, Carolyn J., Mercurio, Ciro, Heierhorst, Jörg and McArthur, Grant A. (2006). Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers. Cancer Research, 66 (16), 8219-8226. doi: 10.1158/0008-5472.CAN-05-3945 |
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2006 Journal Article BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cellsKang, Hyo Jin, Kim, Hee Jeong, Kim, Sang Keun, Barouki, Robert, Cho, Chi-Heum, Khanna, Kum Kum, Rosen, Eliot M. and Bae, Insoo (2006). BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells. The Journal of Biological Chemistry., 281 (21), 14654-14662. doi: 10.1074/jbc.M601613200 |
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2006 Journal Article The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation functionPapp, Laura V., Lu, Jun, Striebel, Frank, Kennedy, Derek, Holmgren, Arne and Khanna, Kum Kum (2006). The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Molecular & Cellular Biology, 26 (13), 4895-4910. doi: 10.1128/MCB.02284-05 |
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2006 Journal Article Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damageKhanna, Kum Kum, Gatei, Magtouf and Tribbick, Gordon (2006). Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage. Methods in Molecular Medicine, 120, 441-452. doi: 10.1385/1-59259-969-9:441 |
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2005 Journal Article Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiationJung, Cha-Gyun, Kim, Hye-Jung, Kawaguchi, Makoto, Khanna, Kum Kum, Hida, Hideki, Asai, Kiyofumi, Nishino, Hitoo and Miura, Yutaka (2005). Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development, 132 (23), 5137-5145. doi: 10.1242/dev.02098 |
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2005 Journal Article Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin associationYoung, David B., Jonnalagadda, Jyoti, Gatei, Magtouf, Jans, David A., Meyn, Stephen and Khanna, Kum Kum (2005). Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association. The Journal of Biological Chemistry, 280 (30), 27587-27594. doi: 10.1074/jbc.M411689200 |
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2005 Journal Article Two ATM variants and breast cancer riskThompson, Deborah, Antoniou, Antonis C., Jenkins, Mark, Marsh, Anna, Chen, Xiaoqing, Wayne, Tierney, Tesoriero, Andrea, Milne, Roger, Spurdle, Amanda, Thorstenson, Yvonne, Southey, Melissa, Giles, Graham G., kConFab Investigators,, Khanna, Kum Kum, Sambrook, Joseph, Oefner, Peter, Goldgar, David, Hopper, John L., Easton, Doug and Chenevix-Trench, Georgia (2005). Two ATM variants and breast cancer risk. Human Mutation, 25 (6), 594-595. doi: 10.1002/humu.9344 |
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2005 Journal Article Involvement of human MOF in ATM functionGupta, Arun, Sharma, Girdhar G., Young, Charles S. H., Agarwal, Manjula, Smith, Edwin R., Paull, Tanya T., Lucchesi, John C., Khanna, Kum Kum, Ludwig, Thomas and Pandita, Tej K. (2005). Involvement of human MOF in ATM function. Molecular and Cellular Biology, 25 (12), 5292-5305. doi: 10.1128/MCB.25.12.5292-5305.2005 |
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2005 Journal Article Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesisFabbro, Megan, Zhou, Bin-Bing, Takahasi, Mikiko, Sarcevic, Boris, Lal, Preeti, Graham, Mark E., Gabrielli, Brian G., Robinson, Phillip J., Nigg, Erich A., Ono, Yoshitaka and Khanna, Kum Kum (2005). Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental Cell, 9 (4), 477-488. doi: 10.1016/j.devcel.2005.09.003 |
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2005 Journal Article Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individualsJekimovs, C. R., Chen, X., Arnold, J., Gatei, M., Richardson, D. J., kConFab Investigators, Spurdle, A. B., Khanna, K. K. and Chenevix-Trench, G. (2005). Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals. British Journal Of Cancer, 92 (4), 784-790. doi: 10.1038/sj.bjc.6602381 |
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2004 Journal Article Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2AGoodarzi, Aaron A, Jonnalagadda, Jyoti C., Douglas, Pauline, Young, David, Ye, Ruiqiong, Moorhead, Greg B. G., Lees-Miller, Susan P. and Khanna, Kum Kum (2004). Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. The EMBO Journal, 23 (22), 4451-4461. doi: 10.1038/sj.emboj.7600455 |
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2004 Journal Article ATM and Genome Maintenance: Defining Its Role in Breast Cancer SusceptibilityKhanna, Kum Kum and Chenevix-Trench, Georgia (2004). ATM and Genome Maintenance: Defining Its Role in Breast Cancer Susceptibility. Journal of Mammary Gland Biology and Neoplasia, 9 (3), 247-262. doi: 10.1023/B:JOMG.0000048772.92326.a1 |
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2004 Journal Article Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaksBuscemi, Giacomo, Perego, Paola, Carenini, Nives, Nakanishi, Makoto, Chessa, Luciana, Chen, Junjie, Khanna, Kum Kum and Delia, Domenico (2004). Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks. Oncogene, 23 (46), 7691-7700. doi: 10.1038/sj.onc.1207986 |
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2004 Journal Article BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damageFabbro, Megan, Savage, Kienan, Hobson, Karen, Deans, Andrew J., Powell, Simon N., McArthur, Grant A. and Khanna, Kum Kum (2004). BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage. The Journal of Biological Chemistry., 279 (30), 31251-31258. doi: 10.1074/jbc.M405372200 |
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2003 Journal Article Suppression of tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1Krause, Darren R., Jonnalagadda,Jyoti C., Gatei, Magtouf H., Sillje, Herman H. W., Zhou, Bin-Bing, Nigg, Erich A. and Khanna, Kumkum (2003). Suppression of tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene, 22 (38), 5927-5937. doi: 10.1038/sj.onc.1206691 |
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2003 Journal Article Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25ASorensen, Claus Storgaard, Syluasen, Randi G., Falck, Jacob, Schroeder, Tine, Ronnstrand, Lars, Khanna, Kum Kum, Zhou, Bin-Bing, Bartek, Jiri and Lukas, Jiri (2003). Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell, 3 (3), 247-258. doi: 10.1016/S1535-6108(03)00048-5 |
