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2008 Journal Article Single-stranded DNA-binding protein hSSB1 is critical for genomic stabilityRichard, Derek J., Bolderson, Emma, Cubeddu, Liza, Wadsworth, Ross I. M., Savage, Kienan, Sharma, Girdhar G., Nicolette, Matthew L., Tsvetanov, Sergie, McIlwraith, Michael J., Pandita, Raj K., Takeda, Shunichi, Hay, Ronald T., Gautier, Jean, West, Stephen C., Paull, Tanya T., Pandita, Tej K., White, Malcolm F. and Khanna, Kum Kum (2008). Single-stranded DNA-binding protein hSSB1 is critical for genomic stability. Nature, 453 (7195), 677-681. doi: 10.1038/nature06883 |
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2007 Journal Article Mutation analysis of five candidate genes in familial breast cancerMarsh, Anna, Healey, Sue, Lewis, Aaron, Spurdle, Amanda B., Kedda, Mary Anne, Khanna, Kum Kum, Mann, Graham J., Pupo, Gulietta M., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2007). Mutation analysis of five candidate genes in familial breast cancer. Breast Cancer Research & Treatment, 105 (3), 377-389. doi: 10.1007/s10549-006-9461-z |
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2007 Journal Article A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBPPagan, Julia K., Arnold, Jeremy, Hanchard, Kim J., Kumar, Raman, Bruno, Tiziana, Jones, Mathew J.K., Richard, Derek J., Forrest, Alistair, Spurdle, Amanda, Verdin, Eric, Crossley, Merlin, Fanciulli, Maurizio, Chenevix-Trench, Georgia, Young, David B. and Khanna, Kum Kum (2007). A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. Journal of Biological Chemistry, 282 (20), 15248-15257. doi: 10.1074/jbc.M700246200 |
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2007 Journal Article Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancerPylkas, K., Tommiska, J., Syrjakoski, K., Kere, J., Gatei, M., Waddell, N., Allinen, M., Karppinen, SM., Rapakko, K., Kaariainen, H., Aittomaki, K., Blomqvist, C., Mustonen, A., Holli, K., Khanna, K.K., Kallioniemi, O.P., Nevanlinna, H. and Winqvist, R. (2007). Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer. Carcinogenesis, 28 (5), 1040-1045. doi: 10.1093/carcin/bgl237 |
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2007 Journal Article From selenium to selenoproteins: Synthesis, identity, and their role in human healthPapp, Laura Vanda, Lu, Jun, Holmgren, Arne and Khanna, Kum Kum (2007). From selenium to selenoproteins: Synthesis, identity, and their role in human health. Antioxidants & Redox Signaling, 9 (7), 775-806. doi: 10.1089/ars.2007.1528 |
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2007 Journal Article BCoR-L1 variation and breast cancerLose, Felicity, Arnold, Jeremy, Young, David B., Brown, Carolyn J., Mann, Graham J., Pupo, Gulietta M., Khanna, Kum Kum, Chenevix-Trench, Georgia and Spurdle, Amanda B. (2007). BCoR-L1 variation and breast cancer. Breast Cancer Research, 9 (4) R54, 1-12. doi: 10.1186/bcr1759 |
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2006 Journal Article Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profilingWaddell, Nic, Jonnalagadda, Jyoti, Marsh, Anna, Grist, Scott, Jenkins, Mark, Hobson, Karen, Taylor, Malcolm, Lindeman, Geoff J., Tavtigian, Sean V., Suthers, Graeme, Goldgar, David, Oefner, Peter J., kConFab Investigators, Taylor, Darrin, Grimmond, Sean, Khanna, Kum Kum and Chenevix-Trench, Georgia (2006). Characterization of the breast cancer associated ATM 7271T>G (V2424G) mutation by gene expression profiling. Genes Chromosomes and Cancer, 45 (12), 1169-1181. doi: 10.1002/gcc.20381 |
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2006 Journal Article Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpointBruno, Tiziana, De Nicola, Francesca, Iezzi, Simona, Lecis, Daniele, D'Angelo, Carmen, Di Padova, Monica, Corbi, Nicoletta, Dimiziani, Leopoldo, Zannini, Laura, Jekimovs, Christian, Scarsella, Marco, Porrello, Alessandro, Chersi, Alberto, Crescenzi, Marco, Leonetti, Carlo, Khanna, Kum Kum, Soddu, Silvia, Floridi, Aristide, Passananti, Claudio, Domenico Delia and Fanciulli, Maurizio (2006). Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint. Cancer Cell, 10 (6), 473-486. doi: 10.1016/j.ccr.2006.10.012 |
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2006 Journal Article EDD mediates DNA damage-induced activation of CHK2Henderson, Michelle J., Munoz, Marcia A, Saunders, Darren N., Clancy, Jennifer L., Russell, Amanda J., Williams, Brandi, Pappin, Darryl, Khanna, Kum Kum, Jackson, Stephen P., Sutherland, Robert L. and Watts, Colin K. W. (2006). EDD mediates DNA damage-induced activation of CHK2. Journal of Biological Chemistry, 281 (52), 39990-40000. doi: 10.1074/jbc.M602818200 |
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2006 Journal Article Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancersDeans, Andrew J., Khanna, Kum Kum, McNees, Carolyn J., Mercurio, Ciro, Heierhorst, Jörg and McArthur, Grant A. (2006). Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers. Cancer Research, 66 (16), 8219-8226. doi: 10.1158/0008-5472.CAN-05-3945 |
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2006 Journal Article BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cellsKang, Hyo Jin, Kim, Hee Jeong, Kim, Sang Keun, Barouki, Robert, Cho, Chi-Heum, Khanna, Kum Kum, Rosen, Eliot M. and Bae, Insoo (2006). BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells. The Journal of Biological Chemistry., 281 (21), 14654-14662. doi: 10.1074/jbc.M601613200 |
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2006 Journal Article The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation functionPapp, Laura V., Lu, Jun, Striebel, Frank, Kennedy, Derek, Holmgren, Arne and Khanna, Kum Kum (2006). The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Molecular & Cellular Biology, 26 (13), 4895-4910. doi: 10.1128/MCB.02284-05 |
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2006 Journal Article Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damageKhanna, Kum Kum, Gatei, Magtouf and Tribbick, Gordon (2006). Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage. Methods in Molecular Medicine, 120, 441-452. doi: 10.1385/1-59259-969-9:441 |
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2005 Journal Article Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiationJung, Cha-Gyun, Kim, Hye-Jung, Kawaguchi, Makoto, Khanna, Kum Kum, Hida, Hideki, Asai, Kiyofumi, Nishino, Hitoo and Miura, Yutaka (2005). Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development, 132 (23), 5137-5145. doi: 10.1242/dev.02098 |
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2005 Journal Article Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin associationYoung, David B., Jonnalagadda, Jyoti, Gatei, Magtouf, Jans, David A., Meyn, Stephen and Khanna, Kum Kum (2005). Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association. The Journal of Biological Chemistry, 280 (30), 27587-27594. doi: 10.1074/jbc.M411689200 |
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2005 Journal Article Involvement of human MOF in ATM functionGupta, Arun, Sharma, Girdhar G., Young, Charles S. H., Agarwal, Manjula, Smith, Edwin R., Paull, Tanya T., Lucchesi, John C., Khanna, Kum Kum, Ludwig, Thomas and Pandita, Tej K. (2005). Involvement of human MOF in ATM function. Molecular and Cellular Biology, 25 (12), 5292-5305. doi: 10.1128/MCB.25.12.5292-5305.2005 |
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2005 Journal Article Two ATM variants and breast cancer riskThompson, Deborah, Antoniou, Antonis C., Jenkins, Mark, Marsh, Anna, Chen, Xiaoqing, Wayne, Tierney, Tesoriero, Andrea, Milne, Roger, Spurdle, Amanda, Thorstenson, Yvonne, Southey, Melissa, Giles, Graham G., kConFab Investigators,, Khanna, Kum Kum, Sambrook, Joseph, Oefner, Peter, Goldgar, David, Hopper, John L., Easton, Doug and Chenevix-Trench, Georgia (2005). Two ATM variants and breast cancer risk. Human Mutation, 25 (6), 594-595. doi: 10.1002/humu.9344 |
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2005 Journal Article Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesisFabbro, Megan, Zhou, Bin-Bing, Takahasi, Mikiko, Sarcevic, Boris, Lal, Preeti, Graham, Mark E., Gabrielli, Brian G., Robinson, Phillip J., Nigg, Erich A., Ono, Yoshitaka and Khanna, Kum Kum (2005). Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental Cell, 9 (4), 477-488. doi: 10.1016/j.devcel.2005.09.003 |
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2005 Journal Article Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individualsJekimovs, C. R., Chen, X., Arnold, J., Gatei, M., Richardson, D. J., kConFab Investigators, Spurdle, A. B., Khanna, K. K. and Chenevix-Trench, G. (2005). Low frequency of CHEK2 1100delC allele in Australian multiple-case breast cancer families: functional analysis in heterozygous individuals. British Journal Of Cancer, 92 (4), 784-790. doi: 10.1038/sj.bjc.6602381 |
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2004 Journal Article Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2AGoodarzi, Aaron A, Jonnalagadda, Jyoti C., Douglas, Pauline, Young, David, Ye, Ruiqiong, Moorhead, Greg B. G., Lees-Miller, Susan P. and Khanna, Kum Kum (2004). Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. The EMBO Journal, 23 (22), 4451-4461. doi: 10.1038/sj.emboj.7600455 |
