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2025 Journal Article Progressive fibrosis in human MASLD is associated with spatially linked transcriptomic signatures of metabolic reprogramming and senescenceVu, Hani, Sun, Yuliangzi, Xiong, Zherui, Tan, Xiao, Radford-Smith, Daniel, Causer, Andrew, Dickens, Alex M., Hyötyläinen, Tuulia, Evstafev, Ilia, Oresic, Matej, Nefzger, Christian, O’Sullivan, Eoin D., Watt, Matthew J., Ramm, Grant A., Clouston, Andrew, Irvine, Katharine, Nguyen, Quan H. and Powell, Elizabeth E. (2025). Progressive fibrosis in human MASLD is associated with spatially linked transcriptomic signatures of metabolic reprogramming and senescence. JHEP Reports 101657, 101657. doi: 10.1016/j.jhepr.2025.101657 |
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2025 Journal Article Impaired viral antigen-specific CD8 T cell responses lead to uncontrolled viral replication in lung tissues in PVM-infected allogeneic bone marrow transplant recipients 4420Hamann, Sophie C., Collinge, Alika D., Olver, Stuart D., Kuns, Rachel D., Yeh, Albert C., Minnie, Simone A., Clouston, Andrew D., Spann, Kirsten M., Phipps, Simon, Degli-Esposti, Mariapia A., Hill, Geoff R., Bialasiewicz, Seweryn and Varelias, Antiopi (2025). Impaired viral antigen-specific CD8 T cell responses lead to uncontrolled viral replication in lung tissues in PVM-infected allogeneic bone marrow transplant recipients 4420. The Journal of Immunology, 214 (Supplement_1) vkaf283.2104. doi: 10.1093/jimmun/vkaf283.2104 |
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2025 Journal Article Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomesZhang, Ping, Haeseleer, Françoise, Waltner, Olivia G., Gartlan, Kate H., Bhise, Shruti S., Minnie, Simone A., Adams, Rachael C., Yeh, Albert C., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Atilla, Erden, Nemychenkov, Nicole S., Nelson, Ethan L., Joshi, Tanvi, Liang, Emily C., Hirayama, Alexandre V., Abe, Kokoro, Koyama, Motoko, Clouston, Andrew D., Gauthier, Jordan, Furlan, Scott N. and Hill, Geoffrey R. (2025). Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes. Immunity, 58 (12), 3024-3039.e7. doi: 10.1016/j.immuni.2025.09.004 |
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2025 Journal Article Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trialsLackner, Carolin, Gouw, Annette S.H., Alves, Venancio, Arola, Johanna, Bedossa, Pierre, Behling, Cynthia, Brunt, Elisabeth M., Burt, Alastair, Clouston, Andrew, Cummings, Oscar, Goodman, Zachary D., Guido, Maria, Guy, Cynthia, Hubscher, Stefan G., Hytiroglou, Prodromos, Kleiner, David, Pai, Rish, Paradis, Valerie, Park, Young Nyun, Rastogi, Archana, Schirmacher, Peter, Wee, Aileen, Yano, Hirohisa, Yeh, Matthew, Avian, Alexander and Tiniakos, Dina G. (2025). Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials. Journal of Hepatology. doi: 10.1016/j.jhep.2025.09.019 |
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2025 Journal Article Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseasesBurgener, Sabrina Sofia, Milner, Mark Thomas, Dey, Shoumit, Morgan, Pooranee K., Blackmore, Daniel G., Frampton, Emmanuelle, Miller, Gregory, Duarte de Oliveira, Monalisa, Kenney, Kirsten Myra, Bajracharya, Rinie, Baumgartner, Ulrich, Collins, Thomas J. C., Xiong, Zherui, Nguyen, Quan, Meikle, Peter J., Bodea, Liviu-Gabriel, Clouston, Andrew, Boucher, Dave, Götz, Jurgen, Murphy, Andrew J., Kaye, Paul M. and Schroder, Kate (2025). Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseases. BioRxiv. doi: 10.1101/2025.04.28.651119 |
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2025 Journal Article Making sense of 'porto-sinusoidal vascular disorder': what does it mean for the pathologist and the patient?Burt, Alastair D., Gouw, Annette S. H., Callea, Francesco, Clouston, Andrew D., Dienes, Hans-Peter, Goodman, Zachary D., Kakar, Sanjay, Kleiner, David E., Lackner, Carolin, Park, Young Nyun, Roberts, Eve A., Schirmacher, Peter, Terracciano, Luigi, Tiniakos, Dina, Torbenson, Michael, Wanless, Ian R., Weber, Achim and Zen, Yoh (2025). Making sense of 'porto-sinusoidal vascular disorder': what does it mean for the pathologist and the patient?. Liver International, 45 (1) e16196, e16196. doi: 10.1111/liv.16196 |
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2024 Journal Article Severe acute liver disease in adults: Contemporary role of histopathologyClouston, Andrew D, Gouw, Annette S H, Tiniakos, Dina, Bedossa, Pierre, Brunt, Elizabeth M, Callea, Francesco, Dienes, Hans-Peter, Goodman, Zachary D, Hubscher, Stefan G, Kakar, Sanjay, Kleiner, David E, Lackner, Carolin, Park, Young N, Roberts, Eve A, Schirmacher, Peter, Terracciano, Luigi, Torbenson, Michael, Wanless, Ian R, Zen, Yoh and Burt, Alastair D (2024). Severe acute liver disease in adults: Contemporary role of histopathology. Histopathology, 85 (4), 549-561. doi: 10.1111/his.15212 |
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2024 Journal Article Steatohepatitic hepatocellular Carcinoma:A new approach to classifying morphological subtypes of hepatocellular carcinomaSoon, Gwyneth S.T., Callea, Francesco, Burt, Alastair D., Cook, Sam, Terracciano, Luigi, Ercan, Caner, Dienes, Hans-Peter, Goodman, Zachary D., Roberts, Eve A., Clouston, Andrew D., Gouw, Annette S.H., Kleiner, David E., Park, Young Nyun, Chung, Taek, Schirmacher, Peter, Tiniakos, Dina, Dimopoulou, Konstantina, Weber, Achim, Endhardt, Katharina and Torbenson, Michael (2024). Steatohepatitic hepatocellular Carcinoma:A new approach to classifying morphological subtypes of hepatocellular carcinoma. Human Pathology, 149, 55-65. doi: 10.1016/j.humpath.2024.06.007 |
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2024 Journal Article Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHDWang, Yewei, Ullah, Md Ashik, Waltner, Olivia G., Bhise, Shruti S., Ensbey, Kathleen S., Schmidt, Christine R., Legg, Samuel R.W., Sekiguchi, Tomoko, Nelson, Ethan L., Kuns, Rachel D., Nemychenkov, Nicole S., Atilla, Erden, Yeh, Albert C., Takahashi, Shuichiro, Boiko, Julie R., Varelias, Antiopi, Blazar, Bruce R., Koyama, Motoko, Minnie, Simone A., Clouston, Andrew D., Furlan, Scott N., Zhang, Ping and Hill, Geoffrey R. (2024). Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Journal of Clinical Investigation, 134 (11) e170125. doi: 10.1172/jci170125 |
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2024 Journal Article IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantationZhang, Ping, Fleming, Peter, Andoniou, Christopher E., Waltner, Olivia G., Bhise, Shruti S., Martins, Jose Paulo, McEnroe, Benjamin A., Voigt, Valentina, Daly, Sheridan, Kuns, Rachel D., Ekwe, Adaeze P., Henden, Andrea S., Saldan, Alda, Olver, Stuart, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R., Ensbey, Kathleen S., Legg, Samuel R.W., Sekiguchi, Tomoko, Minnie, Simone A., Gradwell, Mark, Wagenaar, Irma, Clouston, Andrew D., Koyama, Motoko, Furlan, Scott N., Kennedy, Glen A., Ward, E Sally, Degli-Esposti, Mariapia A. ... Tey, Siok-Keen (2024). IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation. Journal of Clinical Investigation, 134 (7) e174184, 1-15. doi: 10.1172/jci174184 |
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2023 Journal Article Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparityKoyama, Motoko, Hippe, Daniel S., Srinivasan, Sujatha, Proll, Sean C., Miltiadous, Oriana, Li, Naisi, Zhang, Ping, Ensbey, Kathleen S., Hoffman, Noah G., Schmidt, Christine R., Yeh, Albert C., Minnie, Simone A., Strenk, Susan M., Fiedler, Tina L., Hattangady, Namita, Kowalsky, Jacob, Grady, Willian M., Degli-Esposti, Mariapia A., Varelias, Antiopi, Clouston, Andrew D., van den Brink, Marcel R.M., Dey, Neelendu, Randolph, Timothy W., Markey, Kate A., Fredricks, David N. and Hill, Geoffrey R. (2023). Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity. Immunity, 56 (8), 1876-1893.e8. doi: 10.1016/j.immuni.2023.06.024 |
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2023 Journal Article Placental hepatic nodule with molecular subtypingYoung, Vanessa, Clouston, Andrew, Corbett-Burns, Sophie and Russell, Peter (2023). Placental hepatic nodule with molecular subtyping. International Journal of Surgical Pathology, 31 (5), 582-584. doi: 10.1177/10668969221117241 |
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2023 Journal Article Relapsed nodular lymphocyte-predominant Hodgkin lymphoma presenting as severe paraneoplastic hepatitis: a case reportDeacon, Anthony J., Goetz, Naeman N., Weber, Nicholas, Clouston, Andrew, Gonsalkorala, Enoka, Baskerville, Catherine and Leggett, Barbara (2023). Relapsed nodular lymphocyte-predominant Hodgkin lymphoma presenting as severe paraneoplastic hepatitis: a case report. Journal of Medical Case Reports, 17 (1) 269, 1-7. doi: 10.1186/s13256-023-04014-9 |
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2023 Journal Article Patient-Reported Bowel, Urinary, and Sexual Outcomes After Laparoscopic-Assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial (ALaCart)Mercieca-Bebber, Rebecca, Eggins, Renee, Brown, Kilian, Gebski, Val J., Brewer, Kate, Lai, Lenna, Bailey, Lisa, Solomon, Michael J., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Wilson, Kate, Hague, Wendy, Hayes, Julian, White, Stephen, Morgan, Matt, Simes, R. John and Stevenson, Andrew R. L. (2023). Patient-Reported Bowel, Urinary, and Sexual Outcomes After Laparoscopic-Assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial (ALaCart). Annals of Surgery, 277 (3), 449-455. doi: 10.1097/SLA.0000000000005412 |
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2023 Journal Article Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell nicheKoyama, Motoko, Samson, Luke, Ensbey, Kathleen S., Takahashi, Shuichiro, Clouston, Andrew D., Martin, Paul J. and Hill, Geoffrey R. (2023). Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche. Blood, 141 (3), 315-319. doi: 10.1182/blood.2022015808 |
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2023 Journal Article Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumorsLemech, Charlotte, Dredge, Keith, Bampton, Darryn, Hammond, Edward, Clouston, Andrew, Waterhouse, Nigel J, Stanley, Amanda C, Leveque-El Mouttie, Lucie, Chojnowski, Grace M, Haydon, Andrew, Pavlakis, Nick, Burge, Matthew, Brown, Michael P and Goldstein, David (2023). Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors. Journal for ImmunoTherapy of Cancer, 11 (1) e006136, e006136. doi: 10.1136/jitc-2022-006136 |
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2022 Journal Article Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity scorePai, Rish K., Jairath, Vipul, Hogan, Malcolm, Zou, Guangyong, Adeyi, Oyedele A., Anstee, Quentin M., Aqel, Bashar A., Behling, Cynthia, Carey, Elizabeth J., Clouston, Andrew D., Corey, Kathleen, Feagan, Brian G., Kleiner, David E., Ma, Christopher, McFarlane, Stefanie C., Noureddin, Mazen, Ratziu, Vlad, Valasek, Mark A., Younossi, Zobair M., Harrison, Stephen A. and Loomba, Rohit (2022). Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity score. Hepatology, 76 (4), 1150-1163. doi: 10.1002/hep.32475 |
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2022 Journal Article Complexity of ballooned hepatocyte feature recognition: defining a training atlas for artificial intelligence-based imaging in NAFLDBrunt, Elizabeth M., Clouston, Andrew D., Goodman, Zachary, Guy, Cynthia, Kleiner, David E., Lackner, Carolin, Tiniakos, Dina G., Wee, Aileen, Yeh, Matthew, Leow, Wei Qiang, Chng, Elaine, Ren, Yayun, Boon Bee, George Goh, Powell, Elizabeth E., Rinella, Mary, Sanyal, Arun J., Neuschwander-Tetri, Brent, Younossi, Zobair, Charlton, Michael, Ratziu, Vlad, Harrison, Stephen A., Tai, Dean and Anstee, Quentin M. (2022). Complexity of ballooned hepatocyte feature recognition: defining a training atlas for artificial intelligence-based imaging in NAFLD. Journal of Hepatology, 76 (5), 1030-1041. doi: 10.1016/j.jhep.2022.01.011 |
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2022 Journal Article Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of PathologyLohse, Ansgar W., Sebode, Marcial, Bhathal, Prithi S., Clouston, Andrew D., Dienes, Hans P., Jain, Dhanpat, Gouw, Annette S. H., Guindi, Maha, Kakar, Sanjay, Kleiner, David E., Krech, Till, Lackner, Carolin, Longerich, Thomas, Saxena, Romil, Terracciano, Luigi, Washington, Kay, Weidemann, Sören, Hübscher, Stefan G. and Tiniakos, Dina (2022). Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology. Liver International, 42 (5), 1058-1069. doi: 10.1111/liv.15217 |
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2022 Journal Article Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver diseaseKeshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387 |
