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2019

Journal Article

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce B., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota. Immunity, 51 (5), 885-898. doi: 10.1016/j.immuni.2019.08.011

MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

2019

Journal Article

Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials

Pai, Rish K., Kleiner, David E., Hart, John, Adeyi, Oyedele A., Clouston, Andrew D., Behling, Cynthia A., Jain, Dhanpat, Kakar, Sanjay, Brahmania, Mayur, Burgart, Lawrence, Batts, Kenneth P., Valasek, Mark A., Torbenson, Michael S., Guindi, Maha, Wang, Hanlin L., Ajmera, Veeral, Adams, Leon A., Parker, Claire E., Feagan, Brian G., Loomba, Rohit and Jairath, Vipul (2019). Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Alimentary Pharmacology and Therapeutics, 50 (10), 1100-1111. doi: 10.1111/apt.15503

Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials

2019

Journal Article

Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE

Bardou-Jacquet, Edouard, Morandeau, Emilie, Anderson, Gregory J., Ramm, Grant A., Ramm, Louise E., Morcet, Jeff, Bouzille, Guillaume, Dixon, Jeannette, Clouston, Andrew D., Lainé, Fabrice, Turlin, Bruno, Powell, Lawrie W. and Deugnier, Yves M. (2019). Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE. Clinical Gastroenterology and Hepatology, 18 (8), 1851-1857. doi: 10.1016/j.cgh.2019.10.010

Regression of fibrosis stage with treatment reduces long-term risk of liver cancer in patients with hemochromatosis caused by mutation in HFE

2019

Journal Article

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

Gartlan, Kate H., Koyama, Motoko, Lineburg, Katie E., Chang, Karshing, Ensbey, Kathleen S., Kuns, Rachel D., Henden, Andrea S., Samson, Luke D., Clouston, Andrew D., Lopez, Angel F., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2019). Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract. Blood Advances, 3 (19), 2859-2865. doi: 10.1182/bloodadvances.2019000053

Donor T-cell–derived GM-CSF drives alloantigen presentation by dendritic cells in the gastrointestinal tract

2019

Journal Article

IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling

Wilkinson, Andrew N., Chang, Karshing, Kuns, Rachel D., Henden, Andrea S., Minnie, Simone A., Ensbey, Kathleen S., Clouston, Andrew D., Zhang, Ping, Koyama, Motoko, Hidalgo, Juan, Rose-John, Stefan, Varelias, Antiopi, Vuckovic, Slavica, Gartlan, Kate H. and Hill, Geoffrey R. (2019). IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling. Blood, 134 (23), 2092-2106. doi: 10.1182/blood.2019000396

IL-6 dysregulation originates in dendritic cells and initiates graft-versus-host disease via classical signaling

2019

Journal Article

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Vennin, Claire, Melenec, Pauline, Rouet, Romain, Nobis, Max, Cazet, Aurelie S., Murphy, Kendelle J., Herrmann, David, Reed, Daniel A., Lucas, Morghan C., Warren, Sean C., Elgundi, Zehra, Pinese, Mark, Kalna, Gabriella, Roden, Daniel, Samuel, Monisha, Zaratzian, Anaiis, Grey, Shane T., Da Silva, Andrew, Leung, Wilfred, Mathivanan, Suresh, Wang, Yingxiao, Braithwaite, Anthony W., Christ, Daniel, Benda, Ales, Parkin, Ashleigh, Phillips, Phoebe A., Whitelock, John M., Gill, Anthony J., Sansom, Owen J. ... Australian Pancreatic Genome Initiative (APGI) (2019). CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan. Nature Communications, 10 (1) 3637. doi: 10.1038/s41467-019-10968-6

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

2019

Journal Article

Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores

Janubhai Patel, Preya, Chieh-Yu Cheng, Johnson, Banh, Xuan, Gracen, Lucy, Radford-Smith, Daniel, Hossain, Fabrina, Horsfall, Leigh Ula, Lee Hayward, Kelly, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Stuart, Katherine Anne, Russell, Anthony William, Valery, Patricia Casarolli, Clouston, Andrew Donald, Irvine, Katharine Margaret, Bernard, Anne and Powell, Elizabeth Ellen (2019). Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores. Clinical Gastroenterology and Hepatology, 18 (3), 710-718.e4. doi: 10.1016/j.cgh.2019.07.036

Clinically significant fibrosis is associated with longitudinal increases in fibrosis-4 and nonalcoholic fatty liver disease fibrosis scores

2019

Journal Article

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation

Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation

2019

Journal Article

Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial

Stevenson, Andrew R. L., Solomon, Michael J., Brown, Christopher S. B., Lumley, John W., Hewett, Peter, Clouston, Andrew D., Gebski, Val J., Wilson, Kate, Hague, Wendy, Simes, John, on behalf of the Australasian Gastro-Intestinal Trials Group (AGITG) ALaCaRT investigators and Clark, David (2019). Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial. Annals of Surgery, 269 (4), 596-602. doi: 10.1097/SLA.0000000000003021

Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial

2018

Journal Article

Subclassification of hepatocellular adenomas: practical considerations in the implementation of the Bordeaux criteria

Miller, Gregory C., Campbell, Catherine M., Manoharan, Bavahuna, Bryant, Richard, Cavallucci, David, O'Rourke, Nicholas and Clouston, Andrew D. (2018). Subclassification of hepatocellular adenomas: practical considerations in the implementation of the Bordeaux criteria. Pathology, 50 (6), 593-599. doi: 10.1016/j.pathol.2018.05.003

Subclassification of hepatocellular adenomas: practical considerations in the implementation of the Bordeaux criteria

2018

Journal Article

A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care

Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Bernard, Anne, Brown, Nigel Neil, Lampe, Guy, Buck, Lyndall, Saad, Nivene, Russell, Anthony William, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Rosenberg, William and Powell, Elizabeth Ellen (2018). A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care. Hepatology Communications, 2 (8), 893-905. doi: 10.1002/hep4.1208

A pragmatic approach identifies a high rate of nonalcoholic fatty liver disease with advanced fibrosis in diabetes clinics and at-risk populations in primary care

2018

Journal Article

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

Ramnath, Divya, Irvine, Katharine M., Lukowski, Samuel W., Horsfall, Leigh U., Loh, Zhixuan, Clouston, Andrew D., Patel, Preya J., Fagan, Kevin J., Iyer, Abishek, Lampe, Guy, Stow, Jennifer L., Schroder, Kate, Fairlie, David P., Powell, Joseph E., Powell, Elizabeth E. and Sweet, Matthew J. (2018). Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI Insight, 3 (14) e120274. doi: 10.1172/jci.insight.120274

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

2018

Journal Article

Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control

Patel, Preya Janubhai, Hossain, Fabrina, Horsfall, Leigh Ula, Banh, Xuan, Hayward, Kelly Lee, Williams, Suzanne, Johnson, Tracey, Brown, Nigel Neil, Saad, Nivene, Valery, Patricia Casarolli, Irvine, Katharine Margaret, Clouston, Andrew Donald, Stuart, Katherine Anne, Russell, Anthony William and Powell, Elizabeth Ellen (2018). Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control. Journal of Diabetes and its Complications, 32 (8), 799-804. doi: 10.1016/j.jdiacomp.2018.05.008

Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control

2018

Journal Article

Recipient mucosal-associated invariant T cells control GVHD within the colon

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y. W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill, Geoffrey R. (2018). Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation, 128 (5), 1919-1936. doi: 10.1172/JCI91646

Recipient mucosal-associated invariant T cells control GVHD within the colon

2018

Journal Article

Data set for the reporting of intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma and hepatocellular carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Burt, Alastair D, Alves, Venâncio, Bedossa, Pierre, Clouston, Andrew, Guido, Maria, Hübscher, Stefan, Kakar, Sanjay, Ng, Irene, Park, Young N, Reeves, Helen, Wyatt, Judith, Yeh, Matthew M and Ellis, David W (2018). Data set for the reporting of intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma and hepatocellular carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology, 73 (3), 369-385. doi: 10.1111/his.13520

Data set for the reporting of intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma and hepatocellular carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)

2018

Journal Article

PRV: where does the truth lie?

Low, It Wen, Harley, Hugh Alexander John and Clouston, Andrew (2018). PRV: where does the truth lie?. Gastroenterology, 155 (2), e7-e8. doi: 10.1053/j.gastro.2018.01.053

PRV: where does the truth lie?

2018

Journal Article

Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis

Patel, Preya J., Banh, Xuan, Horsfall, Leigh U., Hayward, Kelly L., Hossain, Fabrina, Johnson, Tracey, Stuart, Katherine A., Brown, Nigel N., Saad, Nivene, Clouston, Andrew, Irvine, Katharine M., Russell, Anthony W., Valery, Patricia C., Williams, Suzanne and Powell, Elizabeth E (2018). Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis. Internal Medicine Journal, 48 (2), 144-151. doi: 10.1111/imj.13667

Underappreciation of non-alcoholic fatty liver disease by primary care clinicians: limited awareness of surrogate markers of fibrosis

2018

Journal Article

Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis

Maradana, Muralidhara Rao, Yekollu, Suman Kumar, Zeng, Bijun, Ellis, Jonathan, Clouston, Andrew, Miller, Gregory, Talekar, Meghna, Bhuyan, Zaied Ahmed, Mahadevaiah, Sachin, Powell, Elizabeth E., Irvine, Katharine M., Thomas, Ranjeny and O'Sullivan, Brendan John (2018). Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. Metabolism: Clinical and Experimental, 78, 80-94. doi: 10.1016/j.metabol.2017.09.002

Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis

2018

Journal Article

Pathologic Features of Hereditary Cholestatic Diseases

Clouston, Andrew D. (2018). Pathologic Features of Hereditary Cholestatic Diseases. Surgical Pathology Clinics, 11 (2), 313-327. doi: 10.1016/j.path.2018.02.001

Pathologic Features of Hereditary Cholestatic Diseases

2017

Journal Article

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

Balachandran, Vinod P., Łuksza, Marta, Zhao, Julia N., Makarov, Vladimir, Moral, John Alec, Remark, Romain, Herbst, Brian, Askan, Gokce, Bhanot, Umesh, Senbabaoglu, Yasin, Wells, Daniel K., Cary, Charles Ian Ormsby, Grbovic-Huezo, Olivera, Attiyeh, Marc, Medina, Benjamin, Zhang, Jennifer, Loo, Jennifer, Saglimbeni, Joseph, Abu-Akeel, Mohsen, Zappasodi, Roberta, Riaz, Nadeem, Smoragiewicz, Martin, Larkin Kelley, Z., Basturk, Olca, Gönen, Mithat, Levine, Arnold J., Allen, Peter J., Fearon, Douglas T., Merad, Miriam ... Bassi, Claudio (2017). Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. Nature, 551 (7681), 512-516. doi: 10.1038/nature24462

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer