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2011

Journal Article

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11

Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery

2011

Journal Article

Pharmacokinetic evaluation of fluconazole in critically ill patients

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309

Pharmacokinetic evaluation of fluconazole in critically ill patients

2011

Journal Article

Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats

Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Gobe, Glenda C. and Roberts, Michael S. (2011). Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats. Journal of Biomedical Optics, 16 (11) 116011, 116011-1160118. doi: 10.1117/1.3647597

Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats

2011

Journal Article

Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin

Lin, Lynlee L., Grice, Jeffrey E., Butler, Margaret K., Zvyagin, Andrei V., Becker, Wolfgang, Robertson, Thomas A., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2011). Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin. Pharmaceutical Research, 28 (11), 2920-2930. doi: 10.1007/s11095-011-0515-5

Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin

2011

Journal Article

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

Liu, Xin, Grice, Jeff E., Lademann, Juergen, Otberg, Nina, Trauer, Sindy, Patzelt, Alexa and Roberts, Michael S. (2011). Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man. British Journal of Clinical Pharmacology, 72 (5), 768-774. doi: 10.1111/j.1365-2125.2011.04022.x

Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man

2011

Journal Article

Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies

Wunnapuk, Klintean, Medley, Gregory A., Liu, Xin, Grice, Jeffrey E., Jayasinghe, Sudheera, Gawarammana, Indika, Buckley, Nicholas A. and Roberts, Michael S. (2011). Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 879 (28), 3047-3052. doi: 10.1016/j.jchromb.2011.09.008

Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies

2011

Journal Article

Mathematical models of skin permeability: An overview

Mitragotri, Samir, Anissimov, Yuri G., Bunge, Annette L., Frasch, H. Frederick, Guy, Richard H., Hadgraft, Jonathan, Kasting, Gerald B., Lane, Majella E. and Roberts, Michael S. (2011). Mathematical models of skin permeability: An overview. International Journal of Pharmaceutics, 418 (1), 115-129. doi: 10.1016/j.ijpharm.2011.02.023

Mathematical models of skin permeability: An overview

2011

Journal Article

Modelling dermal drug distribution after topical application in human

Anissimov, Yuri G. and Roberts, Michael Stephen (2011). Modelling dermal drug distribution after topical application in human. Pharmaceutical Research, 28 (9), 2119-2129. doi: 10.1007/s11095-011-0437-2

Modelling dermal drug distribution after topical application in human

2011

Journal Article

Gold nanoparticle penetration and reduced metabolism in human skin by toluene

Labouta, H. I., Liu, D. C., Lin, L. L., Butler, M. K., Grice, J. E., Raphael, A. P., Kraus, T., El-Khordagui, L. K., Soyer, H. P., Roberts, M. S., Schneider, M. and Prow, T. W. (2011). Gold nanoparticle penetration and reduced metabolism in human skin by toluene. Pharmaceutical Research, 28 (11), 2931-2944. doi: 10.1007/s11095-011-0561-z

Gold nanoparticle penetration and reduced metabolism in human skin by toluene

2011

Journal Article

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry

Mostafa, Ahmed, Medley, Gregory, Roberts, Darren M., Mohamed, Mosaad Sayed, Elshanawani, Abdalla A., Roberts, Michael S. and Liu, Xin (2011). Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 879 (23), 2234-2238. doi: 10.1016/j.jchromb.2011.06.006

Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry

2011

Journal Article

Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin

Zhang, Qian, Li, Peng and Roberts, Michael S. (2011). Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin. Journal of Controlled Release, 154 (1), 50-57. doi: 10.1016/j.jconrel.2011.04.018

Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin

2011

Journal Article

Toward a new age of cellular pharmacokinetics in drug discovery

Zhou, Fang, Zhang, Jingwei, Li, Peng, Niu, Fang, Wu, Xiaolan, Wang, Guangji and Roberts, Michael S. (2011). Toward a new age of cellular pharmacokinetics in drug discovery. Drug Metabolism Reviews, 43 (3), 335-345. doi: 10.3109/03602532.2011.560607

Toward a new age of cellular pharmacokinetics in drug discovery

2011

Journal Article

Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo

Thorling, Camilla A., Dancik, Yuri, Hupple, Clinton W., Medley, Gregory, Liu, Xin, Zvyagin, Andrei V., Robertson, Tom A., Burczynski, Frank J. and Roberts, Michael S. (2011). Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo. Journal of Biomedical Optics, 16 (8) 086013, 086013-1-086013-7. doi: 10.1117/1.3614473

Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo

2011

Journal Article

Changes in antibiotic distribution due to pancreatitis

Fanning, Kent J., Robertson, Thomas A., Prins, Johannes B. and Roberts, Michael S. (2011). Changes in antibiotic distribution due to pancreatitis. Antimicrobial Agents and Chemotherapy, 55 (6), 3008-3011. doi: 10.1128/AAC.00416-10

Changes in antibiotic distribution due to pancreatitis

2011

Journal Article

Nanoparticles and microparticles for skin drug delivery

Prow, Tarl W., Grice, Jeffrey E., Lin, Lynlee L., Faye, Rokhaya, Butler, Margaret, Becker, Wolfgang, Wurm, Elisabeth M. T., Yoong, Corinne, Robertson, Thomas A., Soyer, H. Peter and Roberts, Michael S. (2011). Nanoparticles and microparticles for skin drug delivery. Advanced Drug Delivery Reviews, 63 (6), 470-491. doi: 10.1016/j.addr.2011.01.012

Nanoparticles and microparticles for skin drug delivery

2011

Journal Article

How to measure pharmacokinetics in critically ill patients?

Liu, Xin, Kruger, Peter S. and Roberts, Michael S. (2011). How to measure pharmacokinetics in critically ill patients?. Current Pharmaceutical Biotechnology, 12 (12), 2037-2043. doi: 10.2174/138920111798808239

How to measure pharmacokinetics in critically ill patients?

2011

Journal Article

Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy

Roberts, Michael S., Dancik, Yuri, Prow, Tarl W., Thorling, Camilla A., Lin, Lynlee L., Grice, Jeffrey E., Robertson, Thomas A., Koenig, Karsten and Becker, Wolfgang (2011). Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy. European Journal of Pharmaceutics and Biopharmaceutics, 77 (3), 469-488. doi: 10.1016/j.ejpb.2010.12.023

Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy

2011

Journal Article

Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis

Li, Peng, Robertson, Thomas A., Thorling, Camilla A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2011). Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Drug Metabolism and Disposition, 39 (4), 571-579. doi: 10.1124/dmd.110.036806

Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis

2011

Journal Article

Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning

Roberts, Roberts, Darren M., Wilks, Martin F., Roberts, Michael S., Swaminathan, Ramasamyiyer, Mohamed, Fahim, Dawson, Andrew H. and Buckley, Nick A. (2011). Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicology Letters, 202 (1), 69-74. doi: 10.1016/j.toxlet.2011.01.024

Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning

2011

Journal Article

Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research

König, Karsten, Raphael, Anthony P., Lin, Li, Grice, Jeffrey E., Soyer, H. Peter, Breunig, H. Georg, Roberts, Michael S. and Prow, Tarl W. (2011). Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research. Advanced Drug Delivery Reviews, 63 (4-5), 388-404. doi: 10.1016/j.addr.2011.03.002

Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research