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2010

Journal Article

First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008

First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

2010

Journal Article

Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro

Grice, Jeffrey E., Ciotti, Susan, Weiner, Norman, Lockwood, Peter, Cross, Sheree E. and Roberts, Michael S. (2010). Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro. Journal of Pharmaceutical Sciences, 99 (2), 712-718. doi: 10.1002/jps.21856

Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro

2010

Journal Article

Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2

Liu, Xin, Yang, Yan, Zhang, Xiaoxiang, Xu, Shengxin, He, Shufang, Huang, Weijuan and Roberts, Michael S. (2010). Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2. Journal of Gastroenterology and Hepatology, 25 (2), 420-426. doi: 10.1111/j.1440-1746.2009.05981.x

Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2

2010

Journal Article

Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model

Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031

Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model

2010

Book Chapter

Cutaneous metabolism and active transport in transdermal drug delivery

Dancik, Yuri, Thompson, Camilla, Krishnan, Gayathri and Roberts, Michael S. (2010). Cutaneous metabolism and active transport in transdermal drug delivery. Toxicology of the skin. (pp. 69-82) edited by Nancy A. Monteiro-Riviere, A. Wallace Hayes, John A. Thomas and Donald E. Gardner. New York , NY, U.S.A.: Informa Healthcare USA.

Cutaneous metabolism and active transport in transdermal drug delivery

2010

Conference Publication

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

2010

Journal Article

Skin abrasion: Transdermal delivery, cosmetic and immunological applications

Grice, J. E. and Roberts, M. S. (2010). Skin abrasion: Transdermal delivery, cosmetic and immunological applications. Transdermal, 2 (1), 11-16.

Skin abrasion: Transdermal delivery, cosmetic and immunological applications

2010

Journal Article

Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model

Fernando, Germain J. P., Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Fairmaid, Emily J., Roberts, Michael S., Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2010). Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model. PLoS One, 5 (4) e10266, e10266.1-e10266.11. doi: 10.1371/journal.pone.0010266

Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model

2010

Conference Publication

Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin

Geusens, B., Van Gele, M., Braat, S., De Smedt, S. C., Stuart, M. C. A., Prow, T., Sanchez, W., Roberts, M. S., Sanders, N. N. and Lambert, J. (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin. 12th International Conference Perspectives in Percutaneous Penetration, La Grande Motte, France, 7‐10 April, 2010. Oxford, United Kingdom: John Wiley & Sons.

Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin

2010

Conference Publication

ZnO and TiO(2) particles: a study on nanosafety and photoprotection

Popov, Alexey, Zhao, Xin, Zvyagin, Andrei, Lademann, Jürgen, Roberts, Michael, Sanchez, Washington, Priezzhev, Alexander and Myllylä, Risto (2010). ZnO and TiO(2) particles: a study on nanosafety and photoprotection. SPIE Photonics Europe 2010. Biophotonics: Photonic Solutions for Better Health Care, Brussels, Belgium, 12-16 April, 2010. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.854561

ZnO and TiO(2) particles: a study on nanosafety and photoprotection

2010

Book Chapter

Chemical structure-skin transport relationships

Grice, Jeffrey E., Zhang, Qian and Roberts, Michael S. (2010). Chemical structure-skin transport relationships. Toxicology of the skin. (pp. 55-68) edited by Nancy A. Monteiro-Riviere. New York , NY, U.S.A.: Informa Healthcare USA. doi: 10.3109/9781420079180

Chemical structure-skin transport relationships

2010

Conference Publication

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x

Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients

2009

Journal Article

Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin

Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Jenkins, Derek W.K., Roberts, Michael S., Frazer, Ian H., Fernando, Germain J.P. and Kendall, Mark A.F. (2009). Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. Journal of Controlled Release, 139 (3), 212-220. doi: 10.1016/j.jconrel.2009.06.029

Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin

2009

Journal Article

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments

Mutalik, S., Hewavitharana, A., Shaw, P. N., Anissimov, Y. G., Roberts, M. S. and Parekh, H. S. (2009). Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877 (29), 3556-3562. doi: 10.1016/j.jchromb.2009.08.039

Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments

2009

Journal Article

Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets

Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2009). Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets. European Journal of Pharmaceutics and Biopharmaceutics, 73 (3), 404-413. doi: 10.1016/j.ejpb.2009.06.012

Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets

2009

Journal Article

Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers

Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009). Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 (1), 210-215. doi: 10.1128/AAC.00718-08

Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers

2009

Journal Article

Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats

Xia, C.H., Sun, J.G., Wang, G.J., Shang, L.L., Zhang, X.X., Zhang, R., Peng, Y., Wang, X.J., Hao, H.P., Xie, L. and Roberts, M.S. (2009). Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats. Planta Medica: natural products and medicinal plant research, 76 (3), 245-250. doi: 10.1055/s-0029-1186082

Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats

2009

Journal Article

Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver

Fanning, Kent J., Anissimov, Yuri G. and Roberts, Michael S. (2009). Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver. Journal of Pharmaceutical Sciences, 98 (8), 2807-2821. doi: 10.1002/jps.21631

Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver

2009

Journal Article

Skin solubility determines maximum transepidermal flux for similar size molecules

Zhang, Qian, Grice, Jeffrey E., Li, Peng, Jepps, Owen G., Wang, Guang-Ji and Roberts, Michael S. (2009). Skin solubility determines maximum transepidermal flux for similar size molecules. Pharmaceutical Research, 26 (8), 1974-1985. doi: 10.1007/s11095-009-9912-4

Skin solubility determines maximum transepidermal flux for similar size molecules

2009

Journal Article

Liver transporters in hepatic drug disposition: An update

Li, Peng, Wang, Guang-Ji, Robertson, Thomas A. and Roberts, Michael S. (2009). Liver transporters in hepatic drug disposition: An update. Current Drug Metabolism, 10 (5), 482-498. doi: 10.2174/138920009788898037

Liver transporters in hepatic drug disposition: An update