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2009

Conference Publication

Quantitation of stratum corneum depth in the skin surface biopsy by tape stripping

Grice, J. E., Stewart, L. and Roberts, M. S. (2009). Quantitation of stratum corneum depth in the skin surface biopsy by tape stripping. CSPS Symposium 2009: 12th Canadian Society for Pharmaceutical Sciences Annual Meeting, Toronto, ON, Canada, 3-6 June, 2009. Edmonton, AB, Canada: Canadian Society for Pharmaceutical Sciences.

Quantitation of stratum corneum depth in the skin surface biopsy by tape stripping

2009

Conference Publication

Evaluation of ethosomes for delivery of siRNA into cultured primary melanocytes and skin

Geusens, B., Braat, S., Stuart, M., De Smedt, S., Sanders, N., Prow, T., Roberts, M., Lambert, J. and Van Gele, M. (2009). Evaluation of ethosomes for delivery of siRNA into cultured primary melanocytes and skin. 39th Annual European Society for Dermatological Research Meeting, Budapest, Hungary, 10 September 2009. London, United Kingdom: Nature Publishing Group.

Evaluation of ethosomes for delivery of siRNA into cultured primary melanocytes and skin

2009

Conference Publication

Use of fluorescence lifetime imaging (FLIM) to measure skin biology and solute/nanoparticle transport in viable epidermis

Roberts, M.S., Sanchez, W. Jnr, Sanchez, W. Snr, Grice, J., Wu, M. and Prow, T. (2009). Use of fluorescence lifetime imaging (FLIM) to measure skin biology and solute/nanoparticle transport in viable epidermis. Light in Life Sciences Conference 2009, Melbourne, Australia, 24-27 November 2009.

Use of fluorescence lifetime imaging (FLIM) to measure skin biology and solute/nanoparticle transport in viable epidermis

2009

Journal Article

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

2009

Journal Article

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

Kaur, S., Mitchell, G., Vitetta, L. and Roberts, M.S. (2009). Interventions that can reduce inappropriate prescribing in the elderly: A systematic review. Drugs & Ageing, 26 (12), 1013-1028. doi: 10.2165/11318890-000000000-00000

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

2009

Book Chapter

Optimizing drug dosing in the ICU

Kruger, P., Liu, X. and Roberts, M. S. (2009). Optimizing drug dosing in the ICU. Optimizing Drug Dosing in the ICU. (pp. 859-869) edited by Vincent, JL. Berlin, Germany: Springer. doi: 10.1007/978-3-540-92276-6

Optimizing drug dosing in the ICU

2009

Journal Article

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009). Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 (12), 5303-5305. doi: 10.1128/AAC.01600-08

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

2009

Journal Article

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

Park, Sunwoo, Ropella, Glen E. P., Kim, Sean H. J., Roberts, Michael S. and Hunt, C. Anthony (2009). Computational strategies unravel and trace how liver disease changes hepatic drug disposition. Journal of Pharmacology and Experimental Therapeutics, 328 (1), 294-305. doi: 10.1124/jpet.108.142497

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

2008

Journal Article

Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat

Xai, Chun-hua, Sun, Jian-guo, Hao, Hai-ping, Wang, Guang-ji, Yan, Bei, Gu, Sheng-hua, Zheng, Chao-nan, Shang, Li-li and Roberts, Michael S. (2008). Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat. Planta Medica, 74 (15), 1832-1836. doi: 10.1055/s-0028-1088339

Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat

2008

Journal Article

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver

Roberts, Michael S., Roberts, Matthew J., Robertson, Thomas A., Sanchez, Washington, Thorling, Camilla, Zou, Yuhong, Zhao, Xin, Becker, Wolfgang and Zvyagin, Andrei V. (2008). In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver. Journal of Biophotonics, 1 (6), 478-493. doi: 10.1002/jbio.200810058

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver

2008

Journal Article

Common skin conditions and disorders

Roberts, Michael S. (2008). Common skin conditions and disorders. Drug Discovery Today: Disease Mechanisms, 5 (2), 125-126. doi: 10.1016/j.ddmec.2008.09.008

Common skin conditions and disorders

2008

Journal Article

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin

Weiss, Michael, Hung, Daniel Y., Poenicke, Klaus and Roberts, Michael S. (2008). Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin. European Journal of Pharmaceutical Sciences, 34 (4-5), 345-350. doi: 10.1016/j.ejps.2008.05.007

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin

2008

Journal Article

Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes

Cross, Sheree E. and Roberts, Michael S. (2008). Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes. Journal of Pharmaceutical Sciences, 97 (8), 3442-3450. doi: 10.1002/jps.21253

Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes

2008

Journal Article

Nanotechnology, cosmetics and the skin: Is there a health risk?

Nohynek, G. J., Dufour, E. K. and Roberts, M. S. (2008). Nanotechnology, cosmetics and the skin: Is there a health risk?. Skin Pharmacology & Physiology, 21 (3), 136-149. doi: 10.1159/000131078

Nanotechnology, cosmetics and the skin: Is there a health risk?

2008

Journal Article

Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver

Yan, Li, Ropella, Glen E. P., Park, Sunwoo, Roberts, Michael S. and Hunt, C. Anthony (2008). Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver. Pharmaceutical Research, 25 (5), 1023-1036. doi: 10.1007/s11095-007-9494-y

Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver

2008

Journal Article

Skin diseases

Roberts, Michael S. (2008). Skin diseases. Drug Discovery Today: Disease Mechanisms, 5 (1), e1-e2. doi: 10.1016/j.ddmec.2008.09.007

Skin diseases

2008

Journal Article

A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 (3), 240-244. doi: 10.1016/j.ijantimicag.2007.09.013

A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis

2008

Conference Publication

The effect of choice of resuscitation fluid on interstitial tissue antibiotic distribution in acute thermal injury in rats

Cross, Sheree, Dalley, Andrew, Lipman, Jeffery, Ranasinghe, Kanchanamala, Roberts, Michael, Robertson, Thomas and Venkatesh, Bala (2008). The effect of choice of resuscitation fluid on interstitial tissue antibiotic distribution in acute thermal injury in rats. 14th Congress of the International Society for Burn Injuries, Montreal, Canada, 7-11 September 2008.

The effect of choice of resuscitation fluid on interstitial tissue antibiotic distribution in acute thermal injury in rats

2008

Book Chapter

Skin Hydration - A Key Determinant in Topical Absorption

Roberts, M.S., Bouwstra, J., Pirot, F. and Falson, F. (2008). Skin Hydration - A Key Determinant in Topical Absorption. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 115-128) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.

Skin Hydration - A Key Determinant in Topical Absorption

2008

Journal Article

Skin, drug and chemical reactions

Alenius, H., Roberts, D. W., Tokura, Y., Lauerma, A., Patlewicz, G. and Roberts, M. S. (2008). Skin, drug and chemical reactions. Drug Discovery Today: Disease Mechanisms, 5 (2), e211-e220. doi: 10.1016/j.ddmec.2008.06.001

Skin, drug and chemical reactions