|
2020 Journal Article Electrochemical N-demethylation of 14-hydroxy morphinans: sustainable access to opioid antagonistsGlotz, Gabriel, Kappe, C. Oliver and Cantillo, David (2020). Electrochemical N-demethylation of 14-hydroxy morphinans: sustainable access to opioid antagonists. Organic Letters, 22 (17), 6891-6896. doi: 10.1021/acs.orglett.0c02424 |
|
2020 Journal Article A continuous flow cell for high‐temperature/high‐pressure electroorganic synthesisJud, Wolfgang, Kappe, C. Oliver and Cantillo, David (2020). A continuous flow cell for high‐temperature/high‐pressure electroorganic synthesis. ChemElectroChem, 7 (13), 2777-2783. doi: 10.1002/celc.202000696 |
|
2020 Journal Article Organophotocatalytic N‐demethylation of oxycodone using molecular oxygenChen, Yuesu, Glotz, Gabriel, Cantillo, David and Kappe, C. Oliver (2020). Organophotocatalytic N‐demethylation of oxycodone using molecular oxygen. Chemistry: A European Journal, 26 (13), 2973-2979. doi: 10.1002/chem.201905505 |
|
2020 Journal Article Translating batch electrochemistry to single-pass continuous flow conditions: an organic chemist’s guideMaljuric, Snjezana, Jud, Wolfgang, Kappe, C. Oliver and Cantillo, David (2020). Translating batch electrochemistry to single-pass continuous flow conditions: an organic chemist’s guide. Journal of Flow Chemistry, 10 (1), 181-190. doi: 10.1007/s41981-019-00050-z |
|
2019 Journal Article Continuous flow synthesis of terminal epoxides from ketones using in situ generated bromomethyl lithiumvon Keutz, Timo, Cantillo, David and Kappe, C. Oliver (2019). Continuous flow synthesis of terminal epoxides from ketones using in situ generated bromomethyl lithium. Organic Letters, 21 (24), 10094-10098. doi: 10.1021/acs.orglett.9b04072 |
|
2019 Journal Article Continuous flow synthesis of methyl oximino acetoacetate: accessing greener purification methods with inline liquid–liquid extraction and membrane separation technologyLebl, René, Murray, Trevor, Adamo, Andrea, Cantillo, David and Kappe, C. Oliver (2019). Continuous flow synthesis of methyl oximino acetoacetate: accessing greener purification methods with inline liquid–liquid extraction and membrane separation technology. ACS Sustainable Chemistry and Engineering, 7 (24), 20088-20096. doi: 10.1021/acssuschemeng.9b05954 |
|
2019 Journal Article Cathodic C–H trifluoromethylation of arenes and heteroarenes enabled by an in situ-generated triflyltriethylammonium complexJud, Wolfgang, Maljuric, Snjezana, Kappe, C. Oliver and Cantillo, David (2019). Cathodic C–H trifluoromethylation of arenes and heteroarenes enabled by an in situ-generated triflyltriethylammonium complex. Organic Letters, 21 (19), 7970-7975. doi: 10.1021/acs.orglett.9b02948 |
|
2019 Journal Article Continuous generation, in-line quantification and utilization of nitrosyl chloride in photonitrosation reactionsLebl, Rene, Cantillo, David and Kappe, C. Oliver (2019). Continuous generation, in-line quantification and utilization of nitrosyl chloride in photonitrosation reactions. Reaction Chemistry and Engineering, 4 (4), 738-746. doi: 10.1039/c8re00323h |
|
2019 Journal Article Visible light‐promoted Beckmann rearrangements: separating sequential photochemical and thermal phenomena in a continuous flow reactorChen, Yuesu, Cantillo, David and Kappe, C. Oliver (2019). Visible light‐promoted Beckmann rearrangements: separating sequential photochemical and thermal phenomena in a continuous flow reactor. European Journal of Organic Chemistry, 2019 (11), 2163-2171. doi: 10.1002/ejoc.201900231 |
|
2019 Journal Article Enhanced mixing of biphasic liquid-liquid systems for the synthesis of gem-dihalocyclopropanes using packed bed reactorsvon Keutz, Timo, Cantillo, David and Kappe, C. Oliver (2019). Enhanced mixing of biphasic liquid-liquid systems for the synthesis of gem-dihalocyclopropanes using packed bed reactors. Journal of Flow Chemistry, 9 (1), 27-34. doi: 10.1007/s41981-018-0026-1 |
|
2019 Journal Article Continuous-flow protocol for the synthesis of enantiomerically pure intermediates of anti epilepsy and anti tuberculosis active pharmaceutical ingredientsAguiar, Renata M., Leão, Raquel A. C., Mata, Alejandro, Cantillo, David, Kappe, C. Oliver, Miranda, Leandro S. M. and de Souza, Rodrigo O. M. A. (2019). Continuous-flow protocol for the synthesis of enantiomerically pure intermediates of anti epilepsy and anti tuberculosis active pharmaceutical ingredients. Organic and Biomolecular Chemistry, 17 (6), 1552-1557. doi: 10.1039/c8ob03088j |
|
2019 Journal Article On the reactivity of anodically generated trifluoromethyl radicals toward aryl alkynes in organic/aqueous mediaJud, Wolfgang, Kappe, C. Oliver and Cantillo, David (2019). On the reactivity of anodically generated trifluoromethyl radicals toward aryl alkynes in organic/aqueous media. Organic and Biomolecular Chemistry, 17 (14), 3529-3537. doi: 10.1039/c9ob00456d |
|
2018 Journal Article Catalyst‐free oxytrifluoromethylation of alkenes through paired electrolysis in organic‐aqueous mediaJud, Wolfgang, Kappe, C. Oliver and Cantillo, David (2018). Catalyst‐free oxytrifluoromethylation of alkenes through paired electrolysis in organic‐aqueous media. Chemistry: A European Journal, 24 (65), 17234-17238. doi: 10.1002/chem.201804708 |
|
2018 Journal Article Continuous flow photochemical benzylic bromination of a key intermediate in the synthesis of a 2-oxazolidinoneChen, Yuesu, de Frutos, Oscar, Mateos, Carlos, Rincon, Juan A., Cantillo, David and Kappe, C. Oliver (2018). Continuous flow photochemical benzylic bromination of a key intermediate in the synthesis of a 2-oxazolidinone. Chemphotochem, 2 (10), 906-912. doi: 10.1002/cptc.201800114 |
|
2018 Journal Article Continuous flow multistep synthesis of α-functionalized esters via lithium enolate intermediatesvon Keutz, Timo, Strauss, Franz J., Cantillo, David and Kappe, C. Oliver (2018). Continuous flow multistep synthesis of α-functionalized esters via lithium enolate intermediates. Tetrahedron, 74 (25), 3113-3117. doi: 10.1016/j.tet.2017.11.063 |
|
2018 Journal Article Review of Timothy Noël (ed): photochemical processes in continuous flow reactors: from engineering principles to chemical applicationsCantillo, David (2018). Review of Timothy Noël (ed): photochemical processes in continuous flow reactors: from engineering principles to chemical applications. Journal of Flow Chemistry, 8 (2), 107-108. doi: 10.1007/s41981-018-0011-8 |
|
2018 Journal Article Process intensification and integration studies for the generation of a key aminoimidazole intermediate in the synthesis of lanabecestatZnidar, Desiree, Cantillo, David, Inglesby, Phillip, Boyd, Alistair and Kappe, C. Oliver (2018). Process intensification and integration studies for the generation of a key aminoimidazole intermediate in the synthesis of lanabecestat. Organic Process Research and Development, 22 (5), 633-640. doi: 10.1021/acs.oprd.8b00089 |
|
2018 Journal Article Continuous multistep synthesis of 2-(azidomethyl)oxazolesRossa, Thais A., Suveges, Nicolas S., Sa, Marcus M., Cantillo, David and Kappe, C. Oliver (2018). Continuous multistep synthesis of 2-(azidomethyl)oxazoles. Beilstein Journal of Organic Chemistry, 14, 506-514. doi: 10.3762/bjoc.14.36 |
|
2017 Other Outputs Processes and oxazolidine-containing intermediates for the preparation of morphine analogs and derivativesKappe, C. O., Gutmann, B., Weigl, U., Egli, P., Cox, P. D. and Cantillo, D. (2017). Processes and oxazolidine-containing intermediates for the preparation of morphine analogs and derivatives. WO2017185004. |
|
2017 Conference Publication Continuous flow synthesis of 1,4-benzoxazinones via a fully integrated nitration/hydrogenation/cyclization sequenceCantillo, David, Wolf, Bernd, Goetz, Roland and Kappe, C. (2017). Continuous flow synthesis of 1,4-benzoxazinones via a fully integrated nitration/hydrogenation/cyclization sequence. 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Washington, DC United States, 20-24 August 2017. Washington, DC United States: American Chemical Society. |
