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2015

Journal Article

BET inhibitor resistance emerges from leukaemia stem cells

Fong, Chun Yew, Gilan, Omer, Lam, Enid Y.N., Rubin, Alan F., Ftouni, Sarah, Tyler, Dean, Stanley, Kym, Sinha, Devbarna, Yeh, Paul, Morison, Jessica, Giotopoulos, George, Lugo, Dave, Jeffrey, Philip, Lee, Stanley Chun-Wei, Carpenter, Christopher, Gregory, Richard, Ramsay, Robert G., Lane, Steven W., Abdel-Wahab, Omar, Kouzarides, Tony, Johnstone, Ricky W., Dawson, Sarah-Jane, Huntly, Brian J.P., Prinjha, Rab K., Papenfuss, Anthony T. and Dawson, Mark A. (2015). BET inhibitor resistance emerges from leukaemia stem cells. Nature, 525 (7570), 538-542. doi: 10.1038/nature14888

BET inhibitor resistance emerges from leukaemia stem cells

2015

Journal Article

Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice

Boucher, Didier, Vu, Therese, Bain, Amanda L., Tagliaro-Jahns, Marina, Shi, Wei, Lane, Steven W. and Khanna, Kum Kum (2015). Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice. FASEB Journal, 29 (8), 3326-3334. doi: 10.1096/fj.14-269944

Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice

2015

Journal Article

Systematic review and meta-analysis of group cognitive behavioural psychotherapy treatment for sub-clinical depression

Krishna, Murali, Lepping, Peter, Jones, Steven and Lane, Steven (2015). Systematic review and meta-analysis of group cognitive behavioural psychotherapy treatment for sub-clinical depression. Asian Journal of Psychiatry, 16, 7-16. doi: 10.1016/j.ajp.2015.05.043

Systematic review and meta-analysis of group cognitive behavioural psychotherapy treatment for sub-clinical depression

2015

Journal Article

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.

Charmsaz, Sara, Beckett, Kirrilee, Smith, Fiona M., Bruedigam, Claudia, Moore, Andrew S., Al-Ejeh, Fares, Lane, Steven W. and Boyd, Andrew W. (2015). EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.. PLoS One, 10 (6) e0130692, e0130692-e0130692. doi: 10.1371/journal.pone.0130692

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.

2015

Journal Article

Autophagy is required for stem cell mobilization by G-CSF

Leveque-El Mouttie, Lucie, Vu, Therese, Lineburg, Katie E., Kuns, Rachel D., Bagger, Frederik O., Teal, Bianca E., Lor, Mary, Boyle, Glen M., Bruedigam, Claudia, Mintern, Justine D., Hill, Geoffrey R., MacDonald, Kelli P. A. and Lane, Steven W. (2015). Autophagy is required for stem cell mobilization by G-CSF. Blood, 125 (19), 2933-2936. doi: 10.1182/blood-2014-03-562660

Autophagy is required for stem cell mobilization by G-CSF

2015

Journal Article

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

Walter, Dagmar, Lier, Amelie, Geiselhart, Anja, Thalheimer, Frederic B., Huntscha, Sina, Sobotta, Mirko C., Moehrle, Bettina, Brocks, David, Bayindir, Irem, Kaschutnig, Paul, Muedder, Katja, Klein, Corinna, Jauch, Anna, Schroeder, Timm, Geiger, Hartmut, Dick, Tobias, Holland-Letz, Tim, Schmezer, Peter, Lane, Steven W., Rieger, Michael A., Essers, Marieke A. G., Williams, David A., Trumpp, Andreas and Milsom, Michael D. (2015). Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature, 520 (7548), 549-552. doi: 10.1038/nature14131

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

2015

Journal Article

Offending outcomes of a mental health youth diversion pilot scheme in England

Haines, Alina, Lane, Steven, Mcguire, James, Perkins, Elizabeth and Whittington, Richard (2015). Offending outcomes of a mental health youth diversion pilot scheme in England. Criminal Behaviour and Mental Health, 25 (2), 126-140. doi: 10.1002/cbm.1916

Offending outcomes of a mental health youth diversion pilot scheme in England

2015

Journal Article

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

Wallace, Daniel F., Secondes, Eriza S., Rishi, Gautam, Ostini, Lesa, McDonald, Cameron J., Lane, Steven W., Vu, Therese, Hooper, John D., Velasco, Gloria, Ramsay, Andrew J., Lopez-Otin, Carlos and Subramaniam, V. Nathan (2015). A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. British Journal of Haematology, 168 (6), 891-901. doi: 10.1111/bjh.13225

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction

2014

Journal Article

A Review of A Priori Regression Models for Warfarin Maintenance Dose Prediction

Francis, Ben, Lane, Steven, Pirmohamed, Munir and Jorgensen, Andrea (2014). A Review of A Priori Regression Models for Warfarin Maintenance Dose Prediction. Plos One, 9 (12) e114896. doi: 10.1371/journal.pone.0114896

A Review of A Priori Regression Models for Warfarin Maintenance Dose Prediction

2014

Journal Article

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine, Kuhn C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W. (2014). Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy. Cell Stem Cell, 15 (6), 775-790. doi: 10.1016/j.stem.2014.11.010

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

2014

Journal Article

Hit the spleen, JAK!

Lane, Steven W. and Mullally, Ann (2014). Hit the spleen, JAK!. Blood, 124 (19), 2898-2900. doi: 10.1182/blood-2014-09-600635

Hit the spleen, JAK!

2014

Journal Article

A systematic review of the clinical relevance of repetitive transcranial magnetic stimulation

Lepping, P., Schoenfeldt-Lecuona, C., Sambhi, R. S., Lanka, S. V. N., Lane, S., Whittington, R., Leucht, S. and Poole, R. (2014). A systematic review of the clinical relevance of repetitive transcranial magnetic stimulation. Acta Psychiatrica Scandinavica, 130 (5), 326-341. doi: 10.1111/acps.12276

A systematic review of the clinical relevance of repetitive transcranial magnetic stimulation

2014

Journal Article

Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol

van Miert, Clare, Abbott, Janice, Verheoff, Francine, Lane, Steven, Carter, Bernie and McNamara, Paul (2014). Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol. Journal of Advanced Nursing, 70 (10), 2353-2362. doi: 10.1111/jan.12387

Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol

2014

Journal Article

Modulating the stem cell niche for tissue regeneration

Lane, Steven W., Williams, David A. and Watt, Fiona M. (2014). Modulating the stem cell niche for tissue regeneration. Nature Biotechnology, 32 (8), 795-803. doi: 10.1038/nbt.2978

Modulating the stem cell niche for tissue regeneration

2014

Journal Article

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia

Cummins, K. D., Jane, S. M., Ninkovic, S., Bazargan, A., Filshie, R., Sutrave, G., Hertzberg, M., Scott, A., Lane, S., Yannakou, C. K., Ritchie, D., D'Rozario, J., Black, J., Bavishi, K. and Wei, A. (2014). Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia. Blood Cancer Journal, 4 (e237) e237, 1-2. doi: 10.1038/bcj.2014.59

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia

2014

Journal Article

Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation

Pink, J., Pirmohamed, M., Lane, S. and Hughes, D. A. (2014). Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation. Clinical Pharmacology & Therapeutics, 95 (2), 199-207. doi: 10.1038/clpt.2013.190

Cost-Effectiveness of Pharmacogenetics-Guided Warfarin Therapy vs. Alternative Anticoagulation in Atrial Fibrillation

2014

Journal Article

The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

Lane, S. W., Sykes, S. M., Al-Shahrour, F., Shterental, S., Paktinat, M., Lo Celso, C., Jesneck, J. L., Ebert, B. L., Williams, D. A. and Gilliland, D. Gary (2014). The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 123 (2), 301-301. doi: 10.1182/blood-2013-11-540047

The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

2013

Journal Article

The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML

Heidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Doehner, Konstanze, Vasioukhin, Valera, Fischer, Thomas and Armstrong, Scott A. (2013). The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML. Journal of Experimental Medicine, 210 (1), 15-22. doi: 10.1084/jem.20120596

The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML

2013

Journal Article

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo

Zhang, Ping, Tey, Siok-Keen, Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Raju, Jyothy, Leveque, Lucie, Markey, Kate A., Varelias, Antiopi, Clouston, Andrew D., Lane, Steven W., Macdonald, Kelli P. A. and Hill, Geoffrey R. (2013). Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. Journal of Immunology, 191 (10), 5291-5303. doi: 10.4049/jimmunol.1301181

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo

2013

Journal Article

Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies

Joseph, Chacko, Quach, Julie M., Walkley, Carl R., Lane, Steven W., Lo Celso, Cristina and Purton, Louise E. (2013). Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies. Cell Stem Cell, 13 (5), 520-533. doi: 10.1016/j.stem.2013.10.010

Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies