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2012

Journal Article

Towards isozyme-selective HDA inhibitors for interrogating disease

Gupta, Praveer, Reid, Robert C., Iyer, Abishek, Sweet, Matthew J. and Fairlie, David (2012). Towards isozyme-selective HDA inhibitors for interrogating disease. Current Topics in Medicinal Chemistry, 12 (14), 1479-1499. doi: 10.2174/156802612802652420

Towards isozyme-selective HDA inhibitors for interrogating disease

2011

Journal Article

Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats

Iyer, Abishek, Woodruff, Trent M., Wu, Mike C. L., Stylianou, Con, Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and Brown, Lindsay (2011). Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats. Journal of Cardiovascular Pharmacology, 58 (5), 479-486. doi: 10.1097/FJC.0b013e31822a7a09

Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats

2010

Journal Article

Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components

Wheatley, Nicole C., Andrews, Katherine T., Tran, Truc L., Lucke, Andrew J., Reid, Robert C. and Fairlie, David P. (2010). Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7080-7084. doi: 10.1016/j.bmcl.2010.09.096

Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components

2010

Journal Article

Inhibitors selective for HDAC6 in enzymes and cells

Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100

Inhibitors selective for HDAC6 in enzymes and cells

2010

Journal Article

Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938)

Scully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010). Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938). Journal of Medicinal Chemistry, 53 (22), 8208-8208. doi: 10.1021/jm1013314

Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938)

2010

Journal Article

Novel agonists and antagonists for human protease activated receptor 2

Barry, Grant D., Suen, Jacky Y., Le, Giang T., Cotterell, Adam, Reid, Robert C. and Fairlie, David P. (2010). Novel agonists and antagonists for human protease activated receptor 2. Journal of Medicinal Chemistry, 53 (20), 7428-7440. doi: 10.1021/jm100984y

Novel agonists and antagonists for human protease activated receptor 2

2010

Journal Article

Benzhydrylamine linker grafting: A strategy for the improved synthesis of C-terminal peptide amides

Alewood, Dianne, Hopping, Gene, Brust, Andreas, Reid, Robert C. and Alewood, Paul F. (2010). Benzhydrylamine linker grafting: A strategy for the improved synthesis of C-terminal peptide amides. Journal of Peptide Science, 16 (10), 551-557. doi: 10.1002/psc.1248

Benzhydrylamine linker grafting: A strategy for the improved synthesis of C-terminal peptide amides

2010

Journal Article

Selective hexapeptide agonists and antagonists for human complement C3a receptor

Scully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010). Selective hexapeptide agonists and antagonists for human complement C3a receptor. Journal of Medicinal Chemistry, 53 (13), 4938-4948. doi: 10.1021/jm1003705

Selective hexapeptide agonists and antagonists for human complement C3a receptor

2010

Journal Article

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

Halili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

2010

Journal Article

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

Iyer, Abishek, Fenning, Andrew, Lim, Junxian, Le, Giang T, Reid, Robert C, Halili, Maria A, Fairlie, David P and Brown, Lindsay (2010). Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. British Journal of Pharmacology, 159 (7), 1408-1417. doi: 10.1111/j.1476-5381.2010.00637.x

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

2009

Journal Article

The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis

Cantley, M. D., Bartold, P. M., Marino, V, Reid, R. C., Fairlie, D. P., Wyszynski, R. N., Zilm, P. S. and Haynes, D. R. (2009). The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis. Journal of Periodontal Research, 44 (3), 317-322. doi: 10.1111/j.1600-0765.2008.01132.x

The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis

2008

Journal Article

Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism

Tyndall, Joel D. A., Pattenden, Leonard K., Reid, Robert C., Hu, Shu-Hong, Alewood, Dianne, Alewood, Paul F., Walsh, Terry, Fairlie, David P. and Martin, Jennifer L. (2008). Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism. Biochemistry, 47 (12), 3736-3744. doi: 10.1021/bi7023157

Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism

2008

Journal Article

Clean Or dirty - Just how selective do drugs need to be?

Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2008). Clean Or dirty - Just how selective do drugs need to be?. Australian Journal of Chemistry, 61 (9), 654-660. doi: 10.1071/CH08186

Clean Or dirty - Just how selective do drugs need to be?

2007

Journal Article

The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding

Scola, A. M., Higginbottom, A., Partridge, L, J., Reid, R. C., Woodruff, T., Taylor, S. M., Fairlie, D. P. and Monk, P. N. (2007). The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding. Journal of Biological Chemistry, 282 (6), 3664-3671. doi: 10.1074/jbc.M609178200

The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding

2007

Journal Article

Nonpeptidic ligands for peptide-activated G protein-coupled receptors

Blakeney, J. S, Reid, R. C, Le, G. T and Fairlie, D. P (2007). Nonpeptidic ligands for peptide-activated G protein-coupled receptors. Chemical Reviews, 107 (7), 2960-3041. doi: 10.1021/cr050984g

Nonpeptidic ligands for peptide-activated G protein-coupled receptors

2006

Journal Article

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

Gregory, Laura S., Kelly, Wendy L., Reid, Robert C., Fairlie, David P. and Forwood, Mark R. (2006). Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats. Bone, 39 (1), 134-142. doi: 10.1016/j.bone.2005.12.017

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

2006

Journal Article

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006). Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 (11), 7000-7007. doi: 10.4049/jimmunol.176.11.7000

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

2006

Journal Article

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006). Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 (2), 639-648. doi: 10.1128/AAC.50.2.639-648.2006

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

2005

Journal Article

Inhibitors of Secretory Phospholipase A2 Group IIA

Reid, Robert C. (2005). Inhibitors of Secretory Phospholipase A2 Group IIA. Current medicinal chemistry, 12 (25), 3011-3026. doi: 10.2174/092986705774462860

Inhibitors of Secretory Phospholipase A2 Group IIA

2005

Journal Article

A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis

Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005). A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 (5), 883-892. doi: 10.1016/j.intimp.2005.01.003

A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis