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2019

Journal Article

Novel genetic loci affecting facial shape variation in humans

Xiong, Ziyi, Dankova, Gabriela, Howe, Laurence J., Lee, Myoung Keun, Hysi, Pirro G., de Jong, Markus A., Zhu, Gu, Adhikari, Kaustubh, Li, Dan, Li, Yi, Pan, Bo, Feingold, Eleanor, Marazita, Mary L., Shaffer, John R., McAloney, Kerrie, Xu, Shu-Hua, Jin, Li, Wang, Sijia, de Vrij, Femke Ms, Lendemeijer, Bas, Richmond, Stephen, Zhurov, Alexei, Lewis, Sarah, Sharp, Gemma C., Paternoster, Lavinia, Thompson, Holly, Gonzalez-Jose, Rolando, Bortolini, Maria Catira, Canizales-Quinteros, Samuel ... Kayser, Manfred (2019). Novel genetic loci affecting facial shape variation in humans. eLife, 8 e49898. doi: 10.7554/eLife.49898

Novel genetic loci affecting facial shape variation in humans

2019

Journal Article

The Relationship Between Adolescents’ Personality and Neurasthenia: A Comparison of Australian and Chinese

Ye, Lin, Zhu, Gu, Martin, Nick and Liu, Yangyang (2019). The Relationship Between Adolescents’ Personality and Neurasthenia: A Comparison of Australian and Chinese. Journal of Early Adolescence, 39 (9), 1337-1342. doi: 10.1177/0272431618824710

The Relationship Between Adolescents’ Personality and Neurasthenia: A Comparison of Australian and Chinese

2019

Journal Article

Associations of autozygosity with a broad range of human phenotypes

Clark, David W., Okada, Yukinori, Moore, Kristjan H. S., Mason, Dan, Pirastu, Nicola, Gandin, Ilaria, Mattsson, Hannele, Barnes, Catriona L. K., Lin, Kuang, Zhao, Jing Hua, Deelen, Patrick, Rohde, Rebecca, Schurmann, Claudia, Guo, Xiuqing, Giulianini, Franco, Zhang, Weihua, Medina-Gomez, Carolina, Karlsson, Robert, Bao, Yanchun, Bartz, Traci M., Baumbach, Clemens, Biino, Ginevra, Bixley, Matthew J., Brumat, Marco, Chai, Jin-Fang, Corre, Tanguy, Cousminer, Diana L., Dekker, Annelot M., Eccles, David A. ... Wilson, James F. (2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10 (1) 4957, 4957. doi: 10.1038/s41467-019-12283-6

Associations of autozygosity with a broad range of human phenotypes

2019

Journal Article

Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition

Van Der Meer, Dennis, Sønderby, Ida E., Kaufmann, Tobias, Walters, G. Bragi, Abdellaoui, Abdel, Ames, David, Amunts, Katrin, Andersson, Micael, Armstrong, Nicola J., Bernard, Manon, Blackburn, Nicholas B., Blangero, John, Boomsma, Dorret I., Brodaty, Henry, Brouwer, Rachel M., Bülow, Robin, Cahn, Wiepke, Calhoun, Vince D., Caspers, Svenja, Cavalleri, Gianpiero L., Ching, Christopher R. K., Cichon, Sven, Ciufolini, Simone, Corvin, Aiden, Crespo-Facorro, Benedicto, Curran, Joanne E., Dalvie, Shareefa, Dazzan, Paola, De Geus, Eco J. C. ... Andreassen, Ole A. (2019). Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition. JAMA Psychiatry, 77 (4), 1-11. doi: 10.1001/jamapsychiatry.2019.3779

Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition

2019

Journal Article

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Gallagher, C. S., Mäkinen, N., Harris, H. R., Rahmioglu, N., Uimari, O., Cook, J. P., Shigesi, N., Ferreira, T., Velez-Edwards, D. R., Edwards, T. L., Mortlock, S., Ruhioglu, Z., Day, F., Becker, C. M., Karhunen, V., Martikainen, H., Järvelin, M.-R., Cantor, R. M., Ridker, P. M., Terry, K. L., Buring, J. E., Gordon, S. D., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Hinds, D. A., Tung, J. Y., Perry, J. R. B., Lind, P. A. ... Morton, C. C. (2019). Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. Nature Communications, 10 (1) 4857, 4857. doi: 10.1038/s41467-019-12536-4

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

2019

Journal Article

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, Claudia L., Adams, Hieab H. H., Hibar, Derrek P., White, Charles C., Knol, Maria J., Stein, Jason L., Scholz, Markus, Sargurupremraj, Muralidharan, Jahanshad, Neda, Roshchupkin, Gennady V., Smith, Albert V., Bis, Joshua C., Jian, Xueqiu, Luciano, Michelle, Hofer, Edith, Teumer, Alexander, van der Lee, Sven J., Yang, Jingyun, Yanek, Lisa R., Lee, Tom V., Li, Shuo, Hu, Yanhui, Koh, Jia Yu, Eicher, John D., Desrivières, Sylvane, Arias-Vasquez, Alejandro, Chauhan, Ganesh, Athanasiu, Lavinia, Rentería, Miguel E. ... Ikram, M. Arfan (2019). Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics, 51 (11), 1624-1636. doi: 10.1038/s41588-019-0511-y

Genetic architecture of subcortical brain structures in 38,851 individuals

2019

Other Outputs

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

Campos, Adrián I., García-Marín, Luis M., Byrne, Enda M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2019). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317). doi: 10.1101/808691

Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

2019

Journal Article

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, Caroline M., Maihofer, Adam X., Klengel, Torsten, Atkinson, Elizabeth G., Chen, Chia-Yen, Choi, Karmel W., Coleman, Jonathan R. I., Dalvie, Shareefa, Duncan, Laramie E., Gelernter, Joel, Levey, Daniel F., Logue, Mark W., Polimanti, Renato, Provost, Allison C., Ratanatharathorn, Andrew, Stein, Murray B., Torres, Katy, Aiello, Allison E., Almli, Lynn M., Amstadter, Ananda B., Andersen, Søren B., Andreassen, Ole A., Arbisi, Paul A., Ashley-Koch, Allison E., Austin, S. Bryn, Avdibegovic, Esmina, Babić, Dragan, Bækvad-Hansen, Marie, Baker, Dewleen G. ... Koenen, Karestan C. (2019). International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nature Communications, 10 (1) 4558, 4558. doi: 10.1038/s41467-019-12576-w

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

2019

Journal Article

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Tin, Adrienne, Marten, Jonathan, Halperin Kuhns, Victoria L., Li, Yong, Wuttke, Matthias, Kirsten, Holger, Sieber, Karsten B., Qiu, Chengxiang, Gorski, Mathias, Yu, Zhi, Giri, Ayush, Sveinbjornsson, Gardar, Li, Man, Chu, Audrey Y., Hoppmann, Anselm, O’Connor, Luke J., Prins, Bram, Nutile, Teresa, Noce, Damia, Akiyama, Masato, Cocca, Massimiliano, Ghasemi, Sahar, van der Most, Peter J., Horn, Katrin, Xu, Yizhe, Fuchsberger, Christian, Sedaghat, Sanaz, Afaq, Saima, Amin, Najaf ... Köttgen, Anna (2019). Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nature Genetics, 51 (10), 1459-1474. doi: 10.1038/s41588-019-0504-x

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

2019

Conference Publication

Anorexia nervosa genome-wide association study identifies eight loci and implicates psychiatric and metabolic origins

Hubel, C., Watson, H. J., Yilmaz, Z., Landen, M., Martin, N. G., Mortensen, P., Sullivan, P. F., Breen, G. and Bulik, C. M. (2019). Anorexia nervosa genome-wide association study identifies eight loci and implicates psychiatric and metabolic origins. 52nd Conference of the European-Society-of-Human-Genetics (ESHG), Gothenburg Sweden, Jun 15-18, 2019. LONDON: NATURE PUBLISHING GROUP.

Anorexia nervosa genome-wide association study identifies eight loci and implicates psychiatric and metabolic origins

2019

Journal Article

White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group

van Velzen, Laura S., Kelly, Sinead, Isaev, Dmitry, Aleman, Andre, Aftanas, Lyubomir I., Bauer, Jochen, Baune, Bernhard T., Brak, Ivan V., Carballedo, Angela, Connolly, Colm G., Couvy-Duchesne, Baptiste, Cullen, Kathryn R., Danilenko, Konstantin V., Dannlowski, Udo, Enneking, Verena, Filimonova, Elena, Förster, Katharina, Frodl, Thomas, Gotlib, Ian H., Groenewold, Nynke A., Grotegerd, Dominik, Harris, Mathew A., Hatton, Sean N., Hawkins, Emma L., Hickie, Ian B., Ho, Tiffany C., Jansen, Andreas, Kircher, Tilo, Klimes-Dougan, Bonnie ... Schmaal, Lianne (2019). White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group. Molecular Psychiatry, 25 (7), 1511-1525. doi: 10.1038/s41380-019-0477-2

White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group

2019

Other Outputs

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

Munn-Chernoff, Melissa A., Johnson, Emma C., Chou, Yi-Ling, Coleman, Jonathan R.I., Thornton, Laura M., Walters, Raymond K., Yilmaz, Zeynep, Baker, Jessica H., Hübel, Christopher, Gordon, Scott, Medland, Sarah E., Watson, Hunna J., Gaspar, Héléna A., Bryois, Julien, Hinney, Anke, Leppä, Virpi M., Mattheisen, Manuel, Ripke, Stephan, Yao, Shuyang, Giusti-Rodríguez, Paola, Hanscombe, Ken B., Adan, Roger A.H., Alfredsson, Lars, Ando, Tetsuya, Andreassen, Ole A., Berrettini, Wade H., Boehm, Ilka, Boni, Claudette, Perica, Vesna Boraska ... Agrawal, Arpana (2019). Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies. doi: 10.1101/741512

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

2019

Journal Article

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

Van der Spek, Ashley, Broer, Linda, Draisma, Harmen H. M., Pool, René, Albrecht, Eva, Beekman, Marian, Mangino, Massimo, Raag, Mait, Nyholt, Dale R., Dharuri, Harish K., Codd, Veryan, Amin, Najaf, de Geus, Eco J. C., Deelen, Joris, Demirkan, Ayse, Yet, Idil, Fischer, Krista, Haller, Toomas, Henders, Anjali K., Isaacs, Aaron, Medland, Sarah E., Montgomery, Grant W., Mooijaart, Simon P., Strauch, Konstantin, Suchiman, H. Eka D., Vaarhorst, Anika A. M., van Heemst, Diana, Wang-Sattler, Rui, Whitfield, John B. ... Gieger, Christian (2019). Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium. Scientific Reports, 9 (1) 11623, 11623. doi: 10.1038/s41598-019-47282-6

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

2019

Journal Article

Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression

Glanville, Kylie P., Coleman, Jonathan R. I., Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Purves, Kirstin L., Breen, Gerome, Air, Tracy M., Andlauer, Till F. M., Baune, Bernhard T., Binder, Elisabeth B., Blackwood, Douglas H. R., Boomsma, Dorret I., Buttenschøn, Henriette N., Colodro-Conde, Lucía, Dannlowski, Udo, Direk, Nese, Dunn, Erin C., Forstner, Andreas J., de Geus, Eco J. C., Grabe, Hans J., Hamilton, Steven P., Jones, Ian, Jones, Lisa A., Knowles, James A., Kutalik, Zoltán, Levinson, Douglas F., Lewis, Glyn, Lind, Penelope A. ... Børglum, Anders D. (2019). Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression. Biological Psychiatry, 87 (5), 419-430. doi: 10.1016/j.biopsych.2019.06.031

Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression

2019

Journal Article

A behavior genetic analysis of the relationship between humor styles and depression

Kfrerer, Marisa L., Martin, Nicholas G. and Schermer, Julie Aitken (2019). A behavior genetic analysis of the relationship between humor styles and depression. Humor, 32 (3), 417-431. doi: 10.1515/humor-2017-0098

A behavior genetic analysis of the relationship between humor styles and depression

2019

Journal Article

Genetic Similarity Assessment of Twin-Family Populations by Custom-Designed Genotyping Array

Beck, Jeffrey J., Hottenga, Jouke-Jan, Mbarek, Hamdi, Finnicum, Casey T., Ehli, Erik A., Hur, Yoon-Mi, Martin, Nicholas G., De Geus, Eco J.C., Boomsma, Dorret I. and Davies, Gareth E. (2019). Genetic Similarity Assessment of Twin-Family Populations by Custom-Designed Genotyping Array. Twin Research and Human Genetics, 22 (4), 210-219. doi: 10.1017/thg.2019.41

Genetic Similarity Assessment of Twin-Family Populations by Custom-Designed Genotyping Array

2019

Journal Article

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

Evangelou, Evangelos, Gao, He, Chu, Congying, Ntritsos, Georgios, Blakeley, Paul, Butts, Andrew R., Pazoki, Raha, Suzuki, Hideaki, Koskeridis, Fotios, Yiorkas, Andrianos M., Karaman, Ibrahim, Elliott, Joshua, Luo, Qiang, Aeschbacher, Stefanie, Bartz, Traci M., Baumeister, Sebastian E., Braund, Peter S., Brown, Michael R., Brody, Jennifer A., Clarke, Toni-Kim, Dimou, Niki, Faul, Jessica D., Homuth, Georg, Jackson, Anne U., Kentistou, Katherine A., Joshi, Peter K., Lemaitre, Rozenn N., Lind, Penelope A., Lyytikäinen, Leo-Pekka ... Elliott, Paul (2019). New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour, 3 (9), 950-961. doi: 10.1038/s41562-019-0653-z

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

2019

Journal Article

Genetic and environmental risk factors in the non-medical use of over-the-counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population-based sample of young adult twins

Gillespie, Nathan A., Bates, Timothy C., Hickie, Ian B., Medland, Sarah E., Verhulst, Brad, Kirkpatrick, Robert M., Kendler, Kenneth S., Martin, Nicholas G. and Benotsch, Eric G. (2019). Genetic and environmental risk factors in the non-medical use of over-the-counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population-based sample of young adult twins. Addiction, 114 (12) add.14750, 2229-2240. doi: 10.1111/add.14750

Genetic and environmental risk factors in the non-medical use of over-the-counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population-based sample of young adult twins

2019

Journal Article

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Watson, Hunna J., Yilmaz, Zeynep, Thornton, Laura M., Hübel, Christopher, Coleman, Jonathan R. I., Gaspar, Héléna A., Bryois, Julien, Hinney, Anke, Leppä, Virpi M., Mattheisen, Manuel, Medland, Sarah E., Ripke, Stephan, Yao, Shuyang, Giusti-Rodríguez, Paola, Hanscombe, Ken B., Purves, Kirstin L., Adan, Roger A. H., Alfredsson, Lars, Ando, Tetsuya, Andreassen, Ole A., Baker, Jessica H., Berrettini, Wade H., Boehm, Ilka, Boni, Claudette, Perica, Vesna Boraska, Buehren, Katharina, Burghardt, Roland, Cassina, Matteo, Cichon, Sven ... Bulik, Cynthia M. (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51 (8), 1207-1214. doi: 10.1038/s41588-019-0439-2

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

2019

Journal Article

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, Antonio F., Holmans, Peter, Pocklington, Andrew J., Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E., Bishop, Sophie, Cameron, Darren, Hamshere, Marian L., Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H., McCarroll, Steven A., Baune, Bernhard T., Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C., Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M., Plomin, Robert, Porteous, David J., Wray, Naomi R., Caballero, Armando ... Walters, James T. R. (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 51 (7), 1193-1193. doi: 10.1038/s41588-019-0450-7

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection