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2021

Journal Article

Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis

Melhuish Beaupre, Lindsay M., Tiwari, Arun K., Gonçalves, Vanessa F., Zai, Clement C., Marshe, Victoria S., Lewis, Cathryn M., Martin, Nicholas G., McIntosh, Andrew M., Adams, Mark J., Baune, Bernhard T., Levinson, Doug F., Boomsma, Dorret I., Penninx, Brenda W. J. H., Breen, Gerome, Hamilton, Steve, Awasthi, Swapnil, Ripke, Stephan, Jones, Lisa, Jones, Ian, Byrne, Enda M., Hickie, Ian B., Potash, James P., Shi, Jianxin, Weissman, Myrna M., Milaneschi, Yuri, Shyn, Stanley I., Geus, Eco J. C. de, Willemsen, Gonneke, Brown, Gregory M. and Kennedy, James L. (2021). Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis. Frontiers in Psychiatry, 12 734077, 734077. doi: 10.3389/fpsyt.2021.734077

Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: a polygenic risk score analysis

2021

Journal Article

Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder (Nature Communications, (2021), 12, 1, (576), 10.1038/s41467-020-20443-2)

Demontis, Ditte, Walters, Raymond K., Rajagopal, Veera M., Waldman, Irwin D., Grove, Jakob, Als, Thomas D., Dalsgaard, Søren, Ribasés, Marta, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Maria, Werge, Thomas, Nordentoft, Merete, Mors, Ole, Mortensen, Preben Bo, Andreassen, Ole A., Arranz, Maria Jesús, Banaschewski, Tobias, Bau, Claiton, Bellgrove, Mark, Biederman, Joseph, Brikell, Isabell, Buitelaar, Jan K., Burton, Christie L., Casas, Miguel, Crosbie, Jennifer, Doyle, Alysa E., Ebstein, Richard P., Elia, Josephine, Elizabeth, Corfield C. ... Børglum, Anders D. (2021). Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder (Nature Communications, (2021), 12, 1, (576), 10.1038/s41467-020-20443-2). Nature Communications, 12 (1) 1166. doi: 10.1038/s41467-021-21566-w

Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder (Nature Communications, (2021), 12, 1, (576), 10.1038/s41467-020-20443-2)

2021

Journal Article

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

Demontis, Ditte, Walters, Raymond K., Rajagopal, Veera M., Waldman, Irwin D., Grove, Jakob, Als, Thomas D., Dalsgaard, Søren, Ribasas, Marta, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Maria, Werge, Thomas, Nordentoft, Merete, Mors, Ole, Mortensen, Preben Bo, Andreassen, Ole A., Arranz, Maria Jesús, Banaschewski, Tobias, Bau, Claiton, Bellgrove, Mark, Biederman, Joseph, Brikell, Isabell, Buitelaar, Jan K., Burton, Christie L., Casas, Miguel, Crosbie, Jennifer, Doyle, Alysa E., Ebstein, Richard P., Elia, Josephine, Elizabeth, Corfield C. ... ADHD Working Group of the Psychiatric Genomics Consortium (PGC) (2021). Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Nature Communications, 12 (1) 576. doi: 10.1038/s41467-020-20443-2

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

2021

Journal Article

The Eating Disorders Genetics Initiative (EDGI): study protocol

Bulik, Cynthia M., Thornton, Laura M., Parker, Richard, Kennedy, Hannah, Baker, Jessica H., MacDermod, Casey, Guintivano, Jerry, Cleland, Lana, Miller, Allison L., Harper, Lauren, Larsen, Janne T., Yilmaz, Zeynep, Grove, Jakob, Sullivan, Patrick F., Petersen, Liselotte V., Jordan, Jennifer, Kennedy, Martin A. and Martin, Nicholas G. (2021). The Eating Disorders Genetics Initiative (EDGI): study protocol. BMC Psychiatry, 21 (1) 234. doi: 10.1186/s12888-021-03212-3

The Eating Disorders Genetics Initiative (EDGI): study protocol

2021

Journal Article

Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits

García-Marín, Luis M., Campos, Adrián I., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits. Journal of Headache and Pain, 22 (1) 66, 66. doi: 10.1186/s10194-021-01284-w

Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits

2021

Conference Publication

The use of online testing to assess cognitive differences in healthy individuals at high genetic risk of Alzheimer's disease

Lupton, Michelle K., McAloney, Kerrie, Ceslis, Amelia, Robinson, Gail, Thienel, Renate, Breakspear, Michael and Martin, Nicholas G. (2021). The use of online testing to assess cognitive differences in healthy individuals at high genetic risk of Alzheimer's disease. 2021 Alzheimer's Association International Conference, Denver, CO United States, 26 - 30 July 2021. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/alz.055369

The use of online testing to assess cognitive differences in healthy individuals at high genetic risk of Alzheimer's disease

2021

Other Outputs

Lifetime Prevalence and Risk Factors for Perinatal Depression in a Large Cohort of Women with Depression

Kiewa, Jacqueline, Meltzer-Brody, Samantha, Milgrom, Jeanette, Bennett, Elizabeth, Mackle, Tracey, Guintivano, Jerry, Hickie, Ian B, Colodro-Conde, Lucía, Medland, Sarah, Martin, Nicholas G, Wray, Naomi R and Byrne, Enda M (2021). Lifetime Prevalence and Risk Factors for Perinatal Depression in a Large Cohort of Women with Depression. doi: 10.21203/rs.3.rs-362347/v2

Lifetime Prevalence and Risk Factors for Perinatal Depression in a Large Cohort of Women with Depression

2021

Journal Article

Big Five personality traits and illicit drug use: Specificity in trait–drug associations

Dash, Genevieve F., Martin, Nicholas G. and Slutske, Wendy S. (2021). Big Five personality traits and illicit drug use: Specificity in trait–drug associations. Psychology of Addictive Behaviors, 37 (2), 318-330. doi: 10.1037/adb0000793

Big Five personality traits and illicit drug use: Specificity in trait–drug associations

2021

Journal Article

Understanding genetic risk factors for common side effects of antidepressant medications

Campos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8

Understanding genetic risk factors for common side effects of antidepressant medications

2021

Journal Article

Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study

Arends, Rachel M., Pasman, Joëlle A., Verweij, Karin J.H., Derks, Eske M., Gordon, Scott D., Hickie, Ian, Thomas, Nathaniel S., Aliev, Fazil, Zietsch, Brendan P., van der Zee, Matthijs D., Mitchell, Brittany L., Martin, Nicholas G., Dick, Danielle M., Gillespie, Nathan A., de Geus, Eco J.C., Boomsma, Dorret I., Schellekens, Arnt F.A. and Vink, Jacqueline M. (2021). Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study. Addiction Biology, 26 (6) e13015, e13015. doi: 10.1111/adb.13015

Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study

2021

Journal Article

Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3

Nolan, James, Campbell, Purdey J, Brown, Suzanne J, Zhu, Gu, Gordon, Scott, Lim, Ee Mun, Joseph, John, Cross, Simone M, Panicker, Vijay, Medland, Sarah E, Melton, Phillip E, Beilin, Lawrence J, Mori, Trevor A, Mullin, Benjamin H, Pennell, Craig E, Wang, Carol A, Dudbridge, Frank, Walsh, John P, Martin, Nicholas G and Wilson, Scott G (2021). Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3. European Journal of Endocrinology, 185 (5), 743-753. doi: 10.1530/EJE-21-0614

Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3

2021

Journal Article

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

Mitchell, Brittany L., Campos, Adrian I., Whiteman, David C., Olsen, Catherine M., Gordon, Scott D., Walker, Adam J., Dean, Olivia M., Berk, Michael, Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G. and Byrne, Enda M. (2021). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92 (3), 227-235. doi: 10.1016/j.biopsych.2021.10.021

The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes

2021

Journal Article

Genetic and environmental influences on sleep-wake behaviours in adolescence

O'Callaghan, Victoria S., Hansell, Narelle K., Guo, Wei, Carpenter, Joanne S., Shou, Haochang, Strike, Lachlan T., Crouse, Jacob J., McAloney, Kerrie, McMahon, Katie L., Byrne, Enda M., Burns, Jane M., Martin, Nicholas G., Hickie, Ian B., Merikangas, Kathleen R. and Wright, Margaret J. (2021). Genetic and environmental influences on sleep-wake behaviours in adolescence. Sleep Advances, 2 (1) zpab018, zpab018. doi: 10.1093/sleepadvances/zpab018

Genetic and environmental influences on sleep-wake behaviours in adolescence

2021

Journal Article

Genetic and environmental influences on perceived social support: differences by sex and relationship

Coventry, William L., Gillespie, Nathan A., Heath, Andrew C. and Martin, Nicholas G. (2021). Genetic and environmental influences on perceived social support: differences by sex and relationship. Twin Research and Human Genetics, 24 (5) PII S1832427421000438, 251-263. doi: 10.1017/thg.2021.43

Genetic and environmental influences on perceived social support: differences by sex and relationship

2021

Journal Article

Association and genetic overlap between clinical chemistry tests and migraine

Tanha, Hamzeh M, Martin, Nicholas G, Whitfield, John B, Nyholt, Dale R, Gormley, Padhraig, Anttila, Verneri, Winsvold, Bendik S, Palta, Priit, Esko, Tonu, Pers, Tune H, Farh, Kai-How, Cuenca-Leon, Ester, Muona, Mikko, Furlotte, Nicholas A, Kurth, Tobias, Ingason, Andres, McMahon, George, Ligthart, Lannie, Terwindt, Gisela M, Kallela, Mikko, Freilinger, Tobias M, Ran, Caroline, Gordon, Scott G, Stam, Anine H, Steinberg, Stacy, Borck, Guntram, Koiranen, Markku, Quaye, Lydia, Adams, Hieab H H ... Palotie, Aarno (2021). Association and genetic overlap between clinical chemistry tests and migraine. Cephalalgia, 41 (11-12), 1208-1221. doi: 10.1177/03331024211018131

Association and genetic overlap between clinical chemistry tests and migraine

2021

Journal Article

Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight

Beck, Jeffrey J., Pool, René, Van De Weijer, Margot, Chen, Xu, Krapohl, Eva, Gordon, Scott D., Nygaard, Marianne, Debrabant, Birgit, Palviainen, Teemu, Van Der Zee, Matthijs D., Baselmans, Bart, Finnicum, Casey T., Yi, Lu, Lundström, Sebastian, Van Beijsterveldt, Toos, Christiansen, Lene, Heikkilä, Kauko, Kittelsrud, Julie, Loukola, Anu, Ollikainen, Miina, Christensen, Kaare, Martin, Nicholas G., Plomin, Robert, Nivard, Michel, Bartels, Meike, Dolan, Conor, Willemsen, Gonneke, De Geus, Eco, Almqvist, Catarina ... Hottenga, Jouke-Jan (2021). Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight. Human Molecular Genetics, 30 (19), 1894-1905. doi: 10.1093/hmg/ddab121

Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight

2021

Journal Article

Genetic correlation analysis does not associate male pattern baldness with COVID-19

Tanha, Hamzeh M., Medland, Sarah, Martin, Nicholas G. and Nyholt, Dale R. (2021). Genetic correlation analysis does not associate male pattern baldness with COVID-19. Journal of the American Academy of Dermatology, 85 (4), 971-973. doi: 10.1016/j.jaad.2021.05.009

Genetic correlation analysis does not associate male pattern baldness with COVID-19

2021

Journal Article

TH34. EXPLORING THE EFFECT OF DIAGNOSTIC PHENOTYPING AND DISSECTING HETEROGENEITY BETWEEN DEPRESSION SUBTYPES USING THE AUSTRALIAN GENETICS OF DEPRESSION STUDY

Mitchell, Brittany, Campos, Adrian, Whiteman, David, Olsen, Catherine, Hickie, Ian, Medland, Sarah E., Wray, Naomi, Martin, Nicholas G. and Byrne, Enda (2021). TH34. EXPLORING THE EFFECT OF DIAGNOSTIC PHENOTYPING AND DISSECTING HETEROGENEITY BETWEEN DEPRESSION SUBTYPES USING THE AUSTRALIAN GENETICS OF DEPRESSION STUDY. European Neuropsychopharmacology, 51. doi: 10.1016/j.euroneuro.2021.08.207

TH34. EXPLORING THE EFFECT OF DIAGNOSTIC PHENOTYPING AND DISSECTING HETEROGENEITY BETWEEN DEPRESSION SUBTYPES USING THE AUSTRALIAN GENETICS OF DEPRESSION STUDY

2021

Journal Article

Identical twins carry a persistent epigenetic signature of early genome programming

van Dongen, Jenny, Gordon, Scott D., McRae, Allan F., Odintsova, Veronika V., Mbarek, Hamdi, Breeze, Charles E., Sugden, Karen, Lundgren, Sara, Castillo-Fernandez, Juan E., Hannon, Eilis, Moffitt, Terrie E., Hagenbeek, Fiona A., van Beijsterveldt, Catharina E. M., Jan Hottenga, Jouke, Tsai, Pei-Chien, van Dongen, Jenny, Hottenga, Jouke-Jan, McRae, Allan F., Sugden, Karen, Castillo-Fernandez, Juan E., Hannon, Eilis, Moffitt, Terrie E., Hottenga, Jouke-Jan, de Geus, Eco J. C., Spector, Timothy D., Min, Josine L., Hemani, Gibran, Ehli, Erik A., Paul, Franziska ... Genetics of DNA Methylation Consortium (2021). Identical twins carry a persistent epigenetic signature of early genome programming. Nature Communications, 12 (1) 5618, 5618. doi: 10.1038/s41467-021-25583-7

Identical twins carry a persistent epigenetic signature of early genome programming

2021

Other Outputs

Multi-trait genome-wide association study of opioid addiction: OPRM1 and Beyond

Gaddis, Nathan, Mathur, Ravi, Marks, Jesse, Zhou, Linran, Quach, Bryan, Waldrop, Alex, Levran, Orna, Agrawal, Arpana, Randesi, Matthew, Adelson, Miriam, Jeffries, Paul W., Johnson, Emma C., Martin, Nicholas G., Degenhardt, Louisa, Montgomery, Grant W, Wetherill, Leah, Lai, Dongbing, Bucholz, Kathleen, Foroud, Tatiana, Porjesz, Bernice, Webb, Bradley Todd, Crist, Richard C., Kranzler, Henry R., Zhou, Hang, Hulse, Gary, Wildenauer, Dieter, Kelty, Erin, Attia, John, Holliday, Elizabeth G. ... Johnson, Eric O. (2021). Multi-trait genome-wide association study of opioid addiction: OPRM1 and Beyond. doi: 10.1101/2021.09.13.21263503

Multi-trait genome-wide association study of opioid addiction: OPRM1 and Beyond