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2009 Journal Article Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeuticsKeough, Dianne T., Hockova, Dana, Holy, Antonin, Naesens, Lieve M. J., Skinner-Adams, Tina S., de Jersey, John and Guddat, Luke W. (2009). Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry, 52 (14), 4391-4399. doi: 10.1021/jm900267n |
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2009 Journal Article Crystal structure of textilinin-1, a Kunitz-type serine protease inhibitor from the venom of the Australian common brown snake (Pseudonaja textilis)Millers, Emma-Karin K., Trabi, Manuela, Masci, Paul P., Lavin, Martin F., de Jersey, John and Guddat, Luke W. (2009). Crystal structure of textilinin-1, a Kunitz-type serine protease inhibitor from the venom of the Australian common brown snake (Pseudonaja textilis). FEBS Journal, 276 (11), 3163-3175. doi: 10.1111/j.1742-4658.2009.07034.x |
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2009 Journal Article Conformational changes in a plant ketol-acid reductoisomerase upon Mg2+ and NADPH binding as revealed by two crystal structuresLeung, Eleanor W. W. and Guddat, Luke W. (2009). Conformational changes in a plant ketol-acid reductoisomerase upon Mg2+ and NADPH binding as revealed by two crystal structures. Journal of Molecular Biology, 389 (1), 167-182. doi: 10.1016/j.jmb.2009.04.012 |
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2009 Journal Article Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthaseWang, Jian-Guo, Lee, Patrick K.-M., Dong, Yu-Hui, Pang, Siew Siew, Duggleby, Ronald G., Li, Zheng-Ming and Guddat, Luke W. (2009). Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. FEBS Journal, 276 (5), 1282-1290. doi: 10.1111/j.1742-4658.2009.06863.x |
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2009 Book Chapter Snake venom nerve growth factorsLavin, Martin F., Earl, Stephen, Birrell, Geoff, St. Pierre, Liam, Guddat, Luke W., John de Jersey and Masci, Paul (2009). Snake venom nerve growth factors. Handbook of Venoms and Toxins of Reptiles. (pp. 377-392) edited by Stephen P Mackessy. United States of America: CRC Press, Taylor & Francis Group. |
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2009 Journal Article Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acidsMcGeary, Ross P., Vella, Peter, Mak, Jeffery Y. W., Guddat, Luke W. and Schenk, Gerhard (2009). Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. Bioorganic & Medicinal Chemistry Letters, 19 (1), 163-166. doi: 10.1016/j.bmcl.2008.10.125 |
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2008 Journal Article Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenesHadler, K., Tanifum, E.A., Yip, S.H.-C., Mitic, N., Guddat, L.W., Jackson, C.J., Gahan, L.R., Nguyen, K., Carr, P.D., Ollis, D.L., Hengge, A.C., Larrabee, J.A. and Schenk, G. (2008). Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. Journal of the American Chemical Society, 130 (43), 14129-14138. doi: 10.1021/ja803346w |
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2008 Journal Article Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?Hadler, K.ieran S., Huber, Thomas, Cassady, A. Ian, Weber, Jane, Robinson, Jodie, Burrows, Allan, Kelly, Gregory, Guddat, Luke W., Hume, David A., Schenk, Gerhard and Flanagan, Jack U. (2008). Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?. BMC Research Notes, 1 (1) 78, 1-8. doi: 10.1186/1756-0500-1-78 |
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2008 Journal Article Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycleSchenk, Gerhard, Elliott, Tristan W., Leung, Eleanor, Carrington, Lyle E., Mitic, Natasa, Gahan, Lawrence R. and Guddat, Luke W. (2008). Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Structural Biology, 8 (6) 6, 1-13. doi: 10.1186/1472-6807-8-6 |
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2008 Journal Article Structure and mechanism of inhibition of plant acetohydroxyacid synthaseDuggleby, R.G., McCourt, J.A. and Guddat, Luke W. (2008). Structure and mechanism of inhibition of plant acetohydroxyacid synthase. Plant Physiology and Biochemistry, 2008 (46), 309-324. doi: 10.1016/j.plaphy.2007.12.004 |
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2007 Journal Article Plant collagenase: Unique collagenolytic activity of cysteine proteases from gingerKim, M., Hamilton, S. E., Guddat, L. W. and Overall, C. M. (2007). Plant collagenase: Unique collagenolytic activity of cysteine proteases from ginger. Biochimica Et Biophysica Acta General Subjects, 1770 (12), 1627-1635. doi: 10.1016/j.bbagen.2007.08.003 |
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2007 Journal Article Structure, function and diversity of plant purple acid phosphatasesLeung, Eleanor W. W., Teixeira, Marina, Guddat, Luke W., Mitić, Natasa and Schenk, Gerhard (2007). Structure, function and diversity of plant purple acid phosphatases. Current Topics in Plant Biology, 8, 21-31. |
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2006 Journal Article Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferasesKeough, Dianne T., Skinner-Adams, Tina, Jones, Malcolm K., Ng, Ai-Lin., Brereton, Ian M., Guddat, Luke W. and de Jersey, John (2006). Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry, 49 (25), 7479-7486. doi: 10.1021/jm061012j |
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2006 Journal Article Structure-function relationships in human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) by random mutagenesisZheng, Yuan-Zhi, Guddat, Luke, Farlow, Anthony and de Jersey, John (2006). Structure-function relationships in human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) by random mutagenesis. Chemical Research in Chinese Universities, 22 (2), 251-252. doi: 10.1016/S1005-9040(06)60090-1 |
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2006 Journal Article Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanismElliott, T. W., Mitic, N., Gahan, L. R., Guddat, L. W. and Schenk, G. (2006). Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism. Journal of the Brazilian Chemical Society, 17 (8), 1558-1565. doi: 10.1590/S0103-50532006000800011 |
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2006 Journal Article Mammalian-like purple acid phosphatases in plantsDe Jersey, J., Zheng, Yuan-Zhi, Fan, H. K., Schenk, G., Guddat, L. and Hamilton, S. (2006). Mammalian-like purple acid phosphatases in plants. Chemical Research In Chinese Universities, 22 (2), 263-264. doi: 10.1016/S1005-9040(06)60093-7 |
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2006 Conference Publication Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanismElliott, Tristan W., Mitić, Nataša, Gahan, Lawrence R., Guddat, Luke W. and Schenk, Gerhard (2006). Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism. Sociedade Brasileira de Quimica. doi: 10.1590/S0103-50532006000800011 |
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2006 Journal Article Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilisMillers, E. K. I., Masci, P. P., Lavin, M. F., de Jersey, J. and Guddat, L. W. (2006). Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 62 (Pt 7), 642-645. doi: 10.1107/S1744309106019099 |
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2006 Journal Article The Catalytic Mechanisms of Binuclear MetallohydrolasesMitic, Natasa, Smith, Sarah J., Neves, Ademir, Guddat, Luke W., Gahan, Lawrence R. and Schenk, Gerhard (2006). The Catalytic Mechanisms of Binuclear Metallohydrolases. Chemical Reviews, 106 (8), 3338-3363. doi: 10.1021/cr050318f |
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2006 Journal Article Identification and molecular modeling of a novel, plant-like, human purple acid phosphataseFlanagan, J. U., Cassady, A. I., Schenk, G., Guddat, L. W. and Hume, D. A. (2006). Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase. Gene, 377 (1), 12-20. doi: 10.1016/j.gene.2006.02.031 |
