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2018

Journal Article

Emerging peptide science in Australia

Craik, David J. and Payne, Richard J. (2018). Emerging peptide science in Australia. Peptide Science, 110 (3) e24080, e24080. doi: 10.1002/pep2.24080

Emerging peptide science in Australia

2018

Journal Article

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

Agwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553

Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes

2018

Journal Article

Designing macrocyclic disulfide-rich peptides for biotechnological applications

Wang, Conan K. and Craik, David J. (2018). Designing macrocyclic disulfide-rich peptides for biotechnological applications. Nature Chemical Biology, 14 (5), 417-427. doi: 10.1038/s41589-018-0039-y

Designing macrocyclic disulfide-rich peptides for biotechnological applications

2018

Journal Article

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1

Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T. and Craik, David J. (2018). Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. Journal of Medicinal Chemistry, 61 (8), 3674-3684. doi: 10.1021/acs.jmedchem.8b00170

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1

2018

Journal Article

Bioactive compounds isolated from neglected predatory marine gastropods

Turner, Ashlin H., Craik, David J., Kaas, Quentin and Schroeder, Christina I. (2018). Bioactive compounds isolated from neglected predatory marine gastropods. Marine Drugs, 16 (4) 118, 118. doi: 10.3390/md16040118

Bioactive compounds isolated from neglected predatory marine gastropods

2018

Journal Article

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

Castro, Joel, Grundy, Luke, Deiteren, Annemie, Harrington, Andrea M., O'Donnell, Tracey, Maddern, Jessica, Moore, Jessi, Garcia-Caraballo, Sonia, Rychkov, Grigori Y., Yu, Rilei, Kaas, Quentin, Craik, David J., Adams, David J. and Brierley, Stuart M. (2018). Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology, 175 (12), 2384-2398. doi: 10.1111/bph.14115

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

2018

Journal Article

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin

Wang, Conan K., Swedberg, Joakim E., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2018). Conformational Flexibility Is a Determinant of Permeability for Cyclosporin. The Journal of Physical Chemistry. B, 122 (8), 2261-2276. doi: 10.1021/acs.jpcb.7b12419

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin

2018

Journal Article

The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6

Israel, Mathilde R., Thongyoo, Panumart, Deuis, Jennifer R., Craik, David J., Vetter, Irina and Durek, Thomas (2018). The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6. Journal of Medicinal Chemistry, 61 (4), 1730-1736. doi: 10.1021/acs.jmedchem.7b01609

The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6

2017

Journal Article

Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta

Poon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J and Anderson, Marilyn A (2017). Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta. Journal of experimental botany, 69 (3), 633-641. doi: 10.1093/jxb/erx422

Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta

2017

Journal Article

Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors

Durek, Thomas, Shelukhina, Irina V., Tae, Han-Shen, Thongyoo, Panumart, Spirova, Ekaterina N., Kudryavtsev, Denis S., Kasheverov, Igor E., Faure, Grazyna, Corringer, Pierre-Jean, Craik, David J., Adams, David J. and Tsetlin, Victor I. (2017). Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports, 7 (1) 16606, 16606. doi: 10.1038/s41598-017-16809-0

Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors

2017

Journal Article

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017)

Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sonia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017). Biochimica Et Biophysica Acta-Biomembranes, 1859 (11), 2277-2277. doi: 10.1016/j.bbamem.2017.08.008

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017)

2017

Journal Article

Redesigned spider peptide with improved antimicrobial and anticancer properties

Henriques, Sónia Troeira, Lawrence, Nicole, Chaousis, Stephanie, Ravipati, Anjaneya S., Cheneval, Olivier, Benfield, Aurélie H., Elliott, Alysha G., Kavanagh, Angela Maria, Cooper, Matthew A., Chan, Lai Yue, Huang, Yen-Hua and Craik, David J. (2017). Redesigned spider peptide with improved antimicrobial and anticancer properties. ACS Chemical Biology, 12 (9), 2324-2334. doi: 10.1021/acschembio.7b00459

Redesigned spider peptide with improved antimicrobial and anticancer properties

2017

Journal Article

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

Ojeda, Paola G. , Henriques, Sonia Troeira, Pan, Yijun, Nicolazzo, Joseph A., Craik, David J. and Wang, Conan K. (2017). Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake. Biopolymers, 108 (5) e23025, e23025. doi: 10.1002/bip.23025

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

2017

Journal Article

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017). Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 (41), 17101-17112. doi: 10.1074/jbc.M117.808386

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

2017

Journal Article

Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins

Agwa, Akello J., Huang, Yen-Hua, Craik, David J., Henriques, Sonia T. and Schroeder, Christina I. (2017). Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins. Toxins, 9 (8) 248, 248. doi: 10.3390/toxins9080248

Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins

2017

Journal Article

Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds

Craik, David J., Lee, Meng-Han, Rehm, Fabian B.H., Tombling, Benjamin, Doffek, Benjamin and Peacock, Hayden (2017). Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic and Medicinal Chemistry, 26 (10), 2727-2737. doi: 10.1016/j.bmc.2017.08.005

Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds

2017

Journal Article

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors

Wu, Yong, Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Zhangsun, Manqi, Harvey, Peta J., Craik, David J., McIntosh, J. Michael and Luo, Sulan (2017). α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry, 60 (13), 5826-5833. doi: 10.1021/acs.jmedchem.7b00546

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors

2017

Journal Article

Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranes

Cranfield, Charles G., Henriques, Sonia Troeira, Martinac, Boris, Duckworth, Paul, Craik, David J. and Cornell, Bruce (2017). Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranes. Langmuir, 33 (26), 6630-6637. doi: 10.1021/acs.langmuir.7b01642

Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranes

2017

Journal Article

Cyclotides as tools in chemical biology

de Veer, Simon J., Weidmann, Joachim and Craik, David J. (2017). Cyclotides as tools in chemical biology. Accounts of Chemical Research, 50 (7), 1557-1565. doi: 10.1021/acs.accounts.7b00157

Cyclotides as tools in chemical biology

2017

Journal Article

Editorial overview

Craik, David J. and Henriques, Sonia Troeira (2017). Editorial overview. Current Opinion in Chemical Biology, 38, iv-vi. doi: 10.1016/j.cbpa.2017.05.012

Editorial overview