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2012 Journal Article RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRsFranco, Aldo, Kompella, Shiva N., Akondi, Kalyana B., Melaun, Christian, Daly, Norelle L., Luetje, Charles W., Alewood, Paul F., Craik, David J., Adams. David J. and Mari, Frank (2012). RegIIA: An alpha 4/7-conotoxin from the venom of Conus regius that potently blocks alpha 3 beta 4 nAChRs. Biochemical Pharmacology, 83 (3), 419-426. doi: 10.1016/j.bcp.2011.11.006 |
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2012 Journal Article Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar canePinto, Michelle F. S., Fensterseifer, Isabel C. M., Migliolo, Ludovico, Sousa, Daniel A., de Capdville, Guy, Arboleda, Jorge W., Colgrave, Michelle, Craik, David J., Magalhaes, Beatriz S., Dias, Simoni C. and Franco, Octavio L. (2012). Identification and structural characterization of a novel cyclotide with activity against an insect pest of sugar cane. The Journal of Biological Chemistry, 287 (1), 134-147. doi: 10.1074/jbc.M111.294009 |
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2012 Journal Article Engineering cyclic peptide toxinsClark, Richard J. and Craik, David J. (2012). Engineering cyclic peptide toxins. Methods in Enzymology, 503, 57-74. doi: 10.1016/B978-0-12-396962-0.00003-3 |
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2012 Journal Article Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVIDSchroeder, Christina I., Nielsen, Katherine J., Adams, Denise A., Loughnan, Marion L., Thomas, Linda, Alewood, Paul F., Lewis, Richard J. and Craik, David J. (2012). Effects of Lys2 to Ala2 substitutions on the structure and potency of ω-conotoxins MVIIA and CVID. Biopolymers, 98 (4), 345-356. doi: 10.1002/bip.22031 |
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2012 Journal Article ConoServer: updated content, knowledge, and discovery tools in the conopeptide databaseKaas, Quentin, Yu, Rilei, Jin, Ai-Hua, Dutertre, Sebastien and Craik, David J. (2012). ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research, 40 (D1), D325-D330. doi: 10.1093/nar/gkr886 |
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2012 Journal Article The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistanceAndersson, Hakan S., Figueredo, Sharel M., Haugaard-Kedstrom, Linda M., Bengtsson, Elina, Daly, Norelle L., Qu, Xiaoqing, Craik, David J., Ouellette, Andre J. and Rosengren, K. Johan (2012). The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43 (4), 1471-1483. doi: 10.1007/s00726-012-1220-3 |
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2011 Journal Article Engineering of conotoxins for the treatment of painCarstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401 |
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2011 Journal Article A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptorSando, Lillian, Henriques, Sonia Troeira, Foley, Fiona, Simonsen, Shane M., Daly, Norelle L., Hall, Kristopher N., Gustafson, Kirk R., Aguilar, Marie-Isabel and Craik, David J. (2011). A synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. ChemBioChem, 12 (16), 2456-2462. doi: 10.1002/cbic.201100450 |
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2011 Journal Article Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and AnimalsConibear, Anne C. and Craik, David J. (2011). Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals. Israel Journal of Chemistry, 51 (8-9), 908-916. doi: 10.1002/ijch.201100067 |
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2011 Journal Article Cyclotides: A patent reviewSmith, Amanda B., Daly, Norelle L. and Craik, David J. (2011). Cyclotides: A patent review. Expert Opinion On Therapeutic Patents, 21 (11), 1657-1672. doi: 10.1517/13543776.2011.620606 |
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2011 Journal Article Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffoldsChan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141 |
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2011 Journal Article Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptorHalai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r |
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2011 Journal Article α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structureDekan, Zoltan, Vetter, Irina, Daly, Norelle L., Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2011). α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure. Journal of the American Chemical Society, 133 (40), 15866-15869. doi: 10.1021/ja206408q |
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2011 Journal Article Isolation and characterization of cytotoxic cyclotides from Viola philippicaHe, Wenjun, Chan, Lai Yue, Zeng, Guangzhi, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2011). Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides, 32 (8), 1719-1723. doi: 10.1016/j.peptides.2011.06.016 |
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2011 Journal Article Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted foldingDantas de Araujo, Aline, Callaghan, Brid, Nevin, Simon T., Daly, Norelle L., Craik, David J., Moretta, Melissa, Hopping, Gene, Christie, Macdonald J., Adams, David J. and Alewood, Paul F. (2011). Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition), 50 (29), 6527-6529. doi: 10.1002/anie.201101642 |
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2011 Journal Article Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activitiesHenriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393 |
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2011 Journal Article Discovery of an unusual biosynthetic origin for circular proteins in legumesPoth, Aaron G., Colgrave, Michelle L., Lyons, Russell E., Daly, Norelle L. and Craik, David J. (2011). Discovery of an unusual biosynthetic origin for circular proteins in legumes. Proceedings of the National Academy of Sciences of the United State of America, 108 (25), 10127-10132. doi: 10.1073/pnas.1103660108 |
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2011 Journal Article Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1Yuan, Cai, Chen, Liqing, Meehan, Edward J., Daly, Norelle, Craik, David J., Huang, Mingdong and Ngo, Jacky C. (2011). Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1. BMC Structural Biology, 11 (30) 30, 30-1-30-10. doi: 10.1186/1472-6807-11-30 |
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2011 Journal Article Bioactive cystine knot proteinsDaly, Norelle L. and Craik, David J. (2011). Bioactive cystine knot proteins. Current Opinion in Chemical Biology, 15 (3), 362-368. doi: 10.1016/j.cbpa.2011.02.008 |
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2011 Journal Article The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutantWang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153 |
