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2011

Journal Article

Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1

Yuan, Cai, Chen, Liqing, Meehan, Edward J., Daly, Norelle, Craik, David J., Huang, Mingdong and Ngo, Jacky C. (2011). Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1. BMC Structural Biology, 11 (30) 30, 30-1-30-10. doi: 10.1186/1472-6807-11-30

Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1

2011

Journal Article

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

Wang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

2011

Journal Article

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

2011

Journal Article

NMR and protein structure in drug design: Application to cyclotides and conotoxins

Daly, Norelle L., Rosengren, K. Johan, Henriques, Sonia Troeira and Craik, David J. (2011). NMR and protein structure in drug design: Application to cyclotides and conotoxins. European Biophysics Journal, 40 (4), 359-370. doi: 10.1007/s00249-011-0672-9

NMR and protein structure in drug design: Application to cyclotides and conotoxins

2011

Journal Article

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

Yu, Rilei, Craik, David J. and Kaas, Quentin (2011). Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations. PLoS Computational Biology, 7 (3) e1002011, e1002011-1-e1002011-16. doi: 10.1371/journal.pcbi.1002011

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

2011

Journal Article

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

Daly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

2011

Journal Article

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

Clark, Richard J., Tan, Chia Chia, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2011). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry and Biology, 18 (3), 336-343. doi: 10.1016/j.chembiol.2010.12.009

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

2011

Journal Article

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy

Akcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy

2011

Journal Article

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

Aboye, Teshome Leta, Clark, Richard J., Burman, Robert, Roig, Marta Bajona, Craik, David J. and Goransson, Ulf (2011). Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides. Antioxidants & Redox Signaling, 14 (1), 77-86. doi: 10.1089/ars.2010.3112

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

2011

Journal Article

Conopeptides as novel options for pain management

Daly, N. L. and Craik, David J. (2011). Conopeptides as novel options for pain management. Drugs of the Future, 36 (1), 25-32. doi: 10.1358/dof.2011.36.1.1561066

Conopeptides as novel options for pain management

2011

Journal Article

Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization

Lovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J. and Daly, Norelle L. (2011). Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization. Antioxidants and Redox Signaling, 14 (1), 87-95. doi: 10.1089/ars.2009.3068

Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization

2011

Journal Article

The folding of disulfide-rich proteins

Craik, David J. (2011). The folding of disulfide-rich proteins. Antioxidants and Redox Signaling, 14 (1), 61-64. doi: 10.1089/ars.2010.3656

The folding of disulfide-rich proteins

2011

Journal Article

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

2010

Journal Article

Discovery and applications of the plant cyclotides

Craik, David J. (2010). Discovery and applications of the plant cyclotides. Toxicon, 56 (7), 1092-1102. doi: 10.1016/j.toxicon.2010.02.021

Discovery and applications of the plant cyclotides

2010

Journal Article

Naturally occurring circular proteins: Distribution, biosynthesis and evolution

Cascales, Laura and Craik, David J. (2010). Naturally occurring circular proteins: Distribution, biosynthesis and evolution. Organic and Biomolecular Chemistry, 8 (22), 5035-5047. doi: 10.1039/c0ob00139b

Naturally occurring circular proteins: Distribution, biosynthesis and evolution

2010

Journal Article

Peptide rope tricks

Rosengren, K. Johan and Craik, David J. (2010). Peptide rope tricks. Chimica Oggi, 28 (6), 28-32.

Peptide rope tricks

2010

Journal Article

Isolation and characterization of Bioactive Cyclotides from Viola labrilorica

Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of Bioactive Cyclotides from Viola labrilorica. Helvetica Chimica Acta, 93 (11), 2287-2295. doi: 10.1002/hlca.201000115

Isolation and characterization of Bioactive Cyclotides from Viola labrilorica

2010

Journal Article

Structural and functional analysis of human liver-expressed antimicrobial peptide 2

Henriques, Sonia Troeira, Tan, Chia Chia, Craik, David J. and Clark, Richard J. (2010). Structural and functional analysis of human liver-expressed antimicrobial peptide 2. ChemBioChem, 11 (15), 2148-2157. doi: 10.1002/cbic.201000400

Structural and functional analysis of human liver-expressed antimicrobial peptide 2

2010

Journal Article

Isolation, sequencing, and structure - Activity relationships of cyclotides

Ireland, David C., Clark, Richard J., Daly, Norelle L. and Craik, David J. (2010). Isolation, sequencing, and structure - Activity relationships of cyclotides. Journal of Natural Products, 73 (9), 1610-1622. doi: 10.1021/np1000413

Isolation, sequencing, and structure - Activity relationships of cyclotides

2010

Journal Article

Chemical synthesis and structure of the prokineticin Bv8

Morales, Rodrigo A. V., Daly, Norelle L., Vetter, Irina, Mobli, Mehdi, Napier, Ian A., Craik, David J., Lewis, Richard J., Christie, MacDonald J., King, Glenn F., Alewood, Paul F. and Durek, Thomas (2010). Chemical synthesis and structure of the prokineticin Bv8. ChemBioChem, 11 (13), 1882-1888. doi: 10.1002/cbic.201000330

Chemical synthesis and structure of the prokineticin Bv8