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2007

Journal Article

The chemistry and biology of cyclotides

Craik, D. J., Cemazar, M. and Daly, N. L. (2007). The chemistry and biology of cyclotides. Current Opinion In Drug Discovery & Development, 10 (2), 176-184.

The chemistry and biology of cyclotides

2007

Journal Article

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

Daly, Norelle L., Chen, Y, Rosengren, KJ, Marx, UC, Phillips, ML, Waring, AJ, Wang, W, Lehrer, RI and Craik, David J. (2007). Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin. Biochemistry, 46 (35), 9920-9928. doi: 10.1021/bi700720e

Retrocyclin-2: Structural analysis of a potent anti-HIV θ-defensin

2007

Journal Article

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

Gunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540.

The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro

2006

Journal Article

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

Rosengren, K. Johan, Daly, Norelle L., Fornander, Liselotte M., Jonsson, Linda M. H., Shirafuji, Yoshinori, Qu, Xiaoqing, Vogel, Hans J., Ouellette, Andre J. and Craik, David J. (2006). Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4. Journal of Biological Chemistry, 281 (38), 28068-28078. doi: 10.1074/jbc.M604992200

Structural and functional characterization of the conserved salt bridge in mammalian Paneth cell alpha-defensins - Solution structures of mouse cryptdin-4 AND (E15D)-cryptdin-4

2006

Journal Article

The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1

Clark, Richard J., Fischer, Harald, Nevin, Simon T., Adams, David J. and Craik, David J. (2006). The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. Journal of Biological Chemistry, 281 (32), 23254-23263. doi: 10.1074/jbc.M604550200

The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1

2006

Journal Article

A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability

Ireland, D. C., Colgrave, M. L. and Craik, D. J. (2006). A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability. Journal of Peptide Science, 12 (S1), 143-143. doi: 10.1002/psc.797

A novel suite of cyclotides from V. odorata: Sequence variation and the implications for structure, function and stability

2006

Journal Article

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3

Rosengren, K. J., Zhang, S., Lin, F., Daly, N. L., Scott, D. J., Hughes, R. A., Bathgate, R. A. D., Craik, D. J. and Wade, J. D. (2006). Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3. Journal of Biological Chemistry, 281 (38), 28287-28295. doi: 10.1074/jbc.M603829200

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3

2006

Journal Article

Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists

Armishaw, Christopher J., Daly, Norelle L., Nevin, Simon T., Adams, David J., Craik, David J. and Alewood, Paul F. (2006). Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists. Journal of Biological Chemistry, 281 (20), 14136-14143. doi: 10.1074/jbc.M512419200

Alpha-selenoconotoxins, a new class of potent alpha(7) neuronal nicotinic receptor antagonists

2006

Journal Article

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

Ireland, David C., Colgrave, Michelle L., Nguyencong, Philip, Daly, Norelle L. and Craik, David J. (2006). Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins. Journal of Molecular Biology, 357 (5), 1522-1535. doi: 10.1016/j.jmb.2006.01.051

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

2006

Journal Article

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3

Rosengren, K. J., Lin, F., Bathgate, R. A. D., Tregear, G. W., Daly, N. L., Wade, J. D. and Craik, D. J. (2006). Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3. Journal of Biological Chemistry, 281 (9), 5845-5851. doi: 10.1074/jbc.M511210200

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3

2006

Journal Article

Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter

Lovelace, E. S., Armishaw, C. J., Colgrave, M. L., Wahlstrom, M. E., Alewood, P. F., Daly, N. L. and Craik, D. J. (2006). Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter. Journal of Medicinal Chemistry, 49 (22), 6561-6568. doi: 10.1021/jm060299h

Cyclic MrIA: A stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter

2006

Journal Article

NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids

Marx, U. C., Daly, N. L. and Craik, D. J. (2006). NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids. Magnetic Resonance In Chemistry, 44 (Sp. Iss. SI), S41-S50. doi: 10.1002/mrc.1821

NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids

2006

Journal Article

The cyclotide family of circular miniproteins: Nature's combinatorial peptide template

Craik, D. J., Cemazar, M., Wang, C. K. L. and Daly, N. L. (2006). The cyclotide family of circular miniproteins: Nature's combinatorial peptide template. Biopolymers, 84 (3), 250-266. doi: 10.1002/hip.20451

The cyclotide family of circular miniproteins: Nature's combinatorial peptide template

2006

Journal Article

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

Mulvenna, J. P., Mylne, J. S., Bharathi, R., Burton, R. A., Shirley, N. J., Fincher, G. B., Anderson, M. A. and Craik, D. J. (2006). Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?. Plant Cell, 18 (9), 2134-2144. doi: 10.1105/tpc.106.042812

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

2006

Journal Article

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins

Imperial, J. S., Bansal, P. S., Alewood, P. F., Daly, N. L., Craik, D., Sporning, A., Terlau, H., Lopez-Vera, E., Bandyopadhyay, P. K. and Olivera, B. M. (2006). A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry, 45 (27), 8331-8340. doi: 10.1021/bi060263r

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins

2006

Journal Article

Protein disulfide isomerase: the structure of oxidative folding

Gruber, C. W., Cemazar, M., Heras, B., Martin, J. L. and Craik, D. J. (2006). Protein disulfide isomerase: the structure of oxidative folding. Trends In Biochemical Sciences, 31 (8), 455-464. doi: 10.1016/j.tibs.2006.06.001

Protein disulfide isomerase: the structure of oxidative folding

2006

Journal Article

Chemical synthesis and structure elucidation of bovine kappa-casein (1-44)

Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., McGhie, E., Craik, D. J. and Alewood, P. F. (2006). Chemical synthesis and structure elucidation of bovine kappa-casein (1-44). Biochemical And Biophysical Research Communications, 340 (4), 1098-1103. doi: 10.1016/j.bbrc.2005.12.115

Chemical synthesis and structure elucidation of bovine kappa-casein (1-44)

2006

Journal Article

Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif

Cemazar, M. and Craik, D. J. (2006). Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif. International Journal of Peptide Research And Therapeutics, 12 (3), 253-260. doi: 10.1007/s10989-006-9019-2

Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif

2006

Journal Article

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

Daly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

2006

Journal Article

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design

Clark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design