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2006

Journal Article

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

Mulvenna, J. P., Mylne, J. S., Bharathi, R., Burton, R. A., Shirley, N. J., Fincher, G. B., Anderson, M. A. and Craik, D. J. (2006). Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?. Plant Cell, 18 (9), 2134-2144. doi: 10.1105/tpc.106.042812

Discovery of cyclotide-like protein sequences in graminaceous crop plants: Ancestral precursors of circular proteins?

2006

Journal Article

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins

Imperial, J. S., Bansal, P. S., Alewood, P. F., Daly, N. L., Craik, D., Sporning, A., Terlau, H., Lopez-Vera, E., Bandyopadhyay, P. K. and Olivera, B. M. (2006). A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry, 45 (27), 8331-8340. doi: 10.1021/bi060263r

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins

2006

Journal Article

Protein disulfide isomerase: the structure of oxidative folding

Gruber, C. W., Cemazar, M., Heras, B., Martin, J. L. and Craik, D. J. (2006). Protein disulfide isomerase: the structure of oxidative folding. Trends In Biochemical Sciences, 31 (8), 455-464. doi: 10.1016/j.tibs.2006.06.001

Protein disulfide isomerase: the structure of oxidative folding

2006

Journal Article

Chemical synthesis and structure elucidation of bovine kappa-casein (1-44)

Bansal, P. S., Grieve, P. A., Marschke, R. J., Daly, N. L., McGhie, E., Craik, D. J. and Alewood, P. F. (2006). Chemical synthesis and structure elucidation of bovine kappa-casein (1-44). Biochemical And Biophysical Research Communications, 340 (4), 1098-1103. doi: 10.1016/j.bbrc.2005.12.115

Chemical synthesis and structure elucidation of bovine kappa-casein (1-44)

2006

Journal Article

Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif

Cemazar, M. and Craik, D. J. (2006). Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif. International Journal of Peptide Research And Therapeutics, 12 (3), 253-260. doi: 10.1007/s10989-006-9019-2

Factors influencing the stability of cyclotides: Proteins with a circular backbone and cystine knot motif

2006

Journal Article

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

Daly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

2006

Journal Article

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design

Clark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design

2006

Journal Article

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

Chen, B., Colgrave, M. L., Wang, C. N. and Craik, D. J. (2006). Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. Journal of Natural Products, 69 (1), 23-28. doi: 10.1021/np050317i

Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae

2006

Journal Article

The cyclotides and related macrocyclic peptides as scaffolds in drug design

Craik, D. J., Cemazar, M. and Daly, N. L. (2006). The cyclotides and related macrocyclic peptides as scaffolds in drug design. Current Opinion In Drug Discovery & Development, 9 (2), 251-260.

The cyclotides and related macrocyclic peptides as scaffolds in drug design

2006

Journal Article

CyBase: a database of cyclic protein sequence and structure

Mulvenna, J. P., Wang, C. and Craik, D. J. (2006). CyBase: a database of cyclic protein sequence and structure. Nucleic Acids Research, 34 (Sp. Iss. SI), D192-D194. doi: 10.1093/nar/gkj005

CyBase: a database of cyclic protein sequence and structure

2006

Journal Article

Knots in rings - The circular knotted protein momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate

Cemazar, M., Daly, N. L., Haggblad, S., Lo, K. P., Yulyaningsih, E. and Craik, D. J. (2006). Knots in rings - The circular knotted protein momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate. Journal of Biological Chemistry, 281 (12), 8224-8232. doi: 10.1074/jbc.M513399200

Knots in rings - The circular knotted protein momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate

2006

Journal Article

The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold

Daly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200

The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold

2006

Journal Article

theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation

Gallo, S. A., Wang, W., Rawat, S. S., Jung, G., Waring, A. J., Cole, A. M., Lu, H., Yan, X. X., Daly, N. L., Craik, D. J., Jiang, S. B., Lehrer, R. I. and Blumenthal, R. (2006). theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation. Journal of Biological Chemistry, 281 (27), 18787-18792. doi: 10.1074/jbc.M602422200

theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation

2006

Journal Article

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability

Ireland, D. C., Colgrave, M. L. and Craik, D. J. (2006). A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. Biochemical Journal, 400 (Part 1), 1-12. doi: 10.1042/BJ20060627

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability

2006

Journal Article

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

Gunasekera, S., Daly, N. L., Anderson, M. A. and Craik, D. J. (2006). Chemical synthesis and biosynthesis of the cyclotide family of circular proteins. Iubmb Life, 58 (9), 515-524. doi: 10.1080/15216540600889532

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

2005

Journal Article

Isolation and characterization of novel cyclotides from Viola hederaceae - Solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide

Chen, Bin, Colgrave, Michelle L., Daly, Norelle L., Rosengren, K. Johan, Gustafson, Kirk R. and Craik, David J. (2005). Isolation and characterization of novel cyclotides from Viola hederaceae - Solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide. Journal of Biological Chemistry, 280 (23), 22395-22405. doi: 10.1074/jbc.M501737200

Isolation and characterization of novel cyclotides from Viola hederaceae - Solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide

2005

Journal Article

Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance

Kamimori, Hiroshi, Hall, Kristopher, Craik, David J. and Aguilar, Marie-Isabel (2005). Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. Analytical Biochemistry, 337 (1), 149-153. doi: 10.1016/j.ab.2004.10.028

Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance

2005

Journal Article

Threaded rings and complex topologies in novel antimicrobial peptides: Nature's bio-engineering templates

Craik, DJ, Rosengren, KJ, Sando, L and Simonsen, SM (2005). Threaded rings and complex topologies in novel antimicrobial peptides: Nature's bio-engineering templates. Biopolymers, 80 (4), 489-489.

Threaded rings and complex topologies in novel antimicrobial peptides: Nature's bio-engineering templates

2005

Journal Article

The chemistry and biology of human relaxin-3

Tregear, G. W., Bathgate, R. A., Layfield, S., Ferraro, T., Gundlach, A., Ma, S., Lin, F., Hanson, N. F., Summers, R. J., Rosengren, J., Craik, D. J. and Wade, J. D. (2005). The chemistry and biology of human relaxin-3. Relaxin And Related Peptides: Fourth International Conference, 1041, 40-46. doi: 10.1196/annals.1282.008

The chemistry and biology of human relaxin-3

2005

Journal Article

Structure of circulin B and implications for antimicrobial activity of the cyclotides

Koltay, A., Daly, N. L., Gustafson, K. R. and Craik, D. J. (2005). Structure of circulin B and implications for antimicrobial activity of the cyclotides. International Journal of Peptide Research And Therapeutics, 11 (1), 99-106. doi: 10.1007/s10989-004-1722-2

Structure of circulin B and implications for antimicrobial activity of the cyclotides