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2004

Journal Article

Cyclization of pyrrhocoricin retains structural elements crucial for the antimircobial activity of the native peptide

Rosengren, K. J., Goransson, U., Otvos, L. and Craik, D. J. (2004). Cyclization of pyrrhocoricin retains structural elements crucial for the antimircobial activity of the native peptide. Biopolymers, 76 (5), 446-458. doi: 10.1002/bip.20159

Cyclization of pyrrhocoricin retains structural elements crucial for the antimircobial activity of the native peptide

2004

Journal Article

Structures of mu O-conotoxins from Conus marmoreus - Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons

Daly, N. L., Ekberg, J. A., Thomas, L., Adams, D. J., Lewis, R. J. and Craik, D. J. (2004). Structures of mu O-conotoxins from Conus marmoreus - Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. Journal of Biological Chemistry, 279 (24), 25774-25782. doi: 10.1074/jbc.M313002200

Structures of mu O-conotoxins from Conus marmoreus - Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons

2004

Journal Article

Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors

Millard, E. L., Daly, N. L. and Craik, D. J. (2004). Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors. European Journal of Biochemistry, 271 (12), 2320-2326. doi: 10.1111/j.1432-1033.2004.04148.x

Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors

2004

Journal Article

New indole alkaloids from the roots of Ochrosia acuminata

Salim, A. A., Garson, M. J. and Craik, D. J. (2004). New indole alkaloids from the roots of Ochrosia acuminata. Journal of Natural Products, 67 (10), 1719-1721. doi: 10.1021/np049812p

New indole alkaloids from the roots of Ochrosia acuminata

2004

Journal Article

Circular Peptides and Proteins - Preface

Craik, DJ (2004). Circular Peptides and Proteins - Preface. Current Protein & Peptide Science, 5 (5).

Circular Peptides and Proteins - Preface

2004

Journal Article

Solution structure of the cyclotide palicourein: Implications for the development of a pharmaceutical framework

Barry, D. G., Daly, N. L., Bokesch, H. R., Gustafson, K. R. and Craik, D. J. (2004). Solution structure of the cyclotide palicourein: Implications for the development of a pharmaceutical framework. Structure, 12 (1), 85-94. doi: 10.1016/j.str.2003.11.019

Solution structure of the cyclotide palicourein: Implications for the development of a pharmaceutical framework

2004

Journal Article

Functional analysis of the a-defensin disulfide array in mouse cryptdin-4

Maemoto, A., Qu, Xiaoqing, Rosengren, K. J., Tanabe, H, Henschen-Edman, A., Craik, D. J. and Ouellette, A. J. (2004). Functional analysis of the a-defensin disulfide array in mouse cryptdin-4. The Journal of Biological Chemistry, 279 (42), 44188-44196. doi: 10.1074/jbc.M406154200

Functional analysis of the a-defensin disulfide array in mouse cryptdin-4

2004

Journal Article

Discovery, structure and biological activities of the cyclotides

Craik, D. J., Daly, N. L., Mulvenna, J., Plan, M. R. and Trabi, M. (2004). Discovery, structure and biological activities of the cyclotides. Current Protein & Peptide Science, 5 (5), 297-315. doi: 10.2174/1389203043379512

Discovery, structure and biological activities of the cyclotides

2004

Journal Article

New alkaloids from Pandanus amaryllifolius

Salim, Angela A., Garson, Mary J. and Craik, David J. (2004). New alkaloids from Pandanus amaryllifolius. Journal of Natural Products, 67 (1), 54-57. doi: 10.1021/np0303310

New alkaloids from Pandanus amaryllifolius

2004

Journal Article

Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins

Dutton, J. L., Renda, R. F., Waine, C., Clark, R. J., Daly, N. L., Jennings, C. V., Anderson, M. A. and Craik, D. J. (2004). Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins. Journal of Biological Chemistry, 279 (45), 46858-46867. doi: 10.1074/jbc.M407421200

Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins

2004

Journal Article

A nearly idealized 6 '-O-methylated t-carrageenan from the Australian red alga Claviclonium ovatum (Acrotylaceae, Gigartinales)

Chiovitti, A., Bacic, A., Craik, D. J., Kraft, G. T. and Liao, M. L. (2004). A nearly idealized 6 '-O-methylated t-carrageenan from the Australian red alga Claviclonium ovatum (Acrotylaceae, Gigartinales). Carbohydrate Research, 339 (8), 1459-1466. doi: 10.1016/j.carres.2004.03.019

A nearly idealized 6 '-O-methylated t-carrageenan from the Australian red alga Claviclonium ovatum (Acrotylaceae, Gigartinales)

2004

Journal Article

Structure of thermolysin cleaved microcin J25: Extreme stability of a two-chain antimicrobial peptide devoid of covalent links

Rosengren, K. Johan, Blond, Alain, Alfonso, Carlos, Tabet, Jean-Claude, Rebuffat, Sylvie and Craik, David J. (2004). Structure of thermolysin cleaved microcin J25: Extreme stability of a two-chain antimicrobial peptide devoid of covalent links. Biochemistry, 43 (16), 4696-4702. doi: 10.1021/bi0361261

Structure of thermolysin cleaved microcin J25: Extreme stability of a two-chain antimicrobial peptide devoid of covalent links

2003

Journal Article

Enzymatic cyclization of a potent Bowman-Birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide

Marx, Ute C., Korsinczky, Michael L. J., Schirra, Horst Joachim, Jones, Alun, Condie, Barrie, Otvos, Laszlo and Craik, David J. (2003). Enzymatic cyclization of a potent Bowman-Birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide. Journal of Biological Chemistry, 278 (24), 21782-21789. doi: 10.1074/jbc.M212996200

Enzymatic cyclization of a potent Bowman-Birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide

2003

Journal Article

Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII

Blanchfield, J. T., Dutton, J. T., Hogg, R. C., Gallagher, O. P., Craik, D. J., Jones, A., Adams, D. J., Lewis, R. J., Alewood, P. F. and Toth, I. (2003). Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII. Journal of Medicinal Chemistry, 46 (7), 1266-1272. doi: 10.1021/jm020426j

Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII

2003

Journal Article

Twists, knots, and rings in proteins: Structural definition of the cyclotide framework

Rosengren, K. J., Daly, N. L., Plan, M. R., Waine, C. and Craik, D. J. (2003). Twists, knots, and rings in proteins: Structural definition of the cyclotide framework. Journal of Biological Chemistry, 278 (10), 8606-8616. doi: 10.1074/jbc.M211147200

Twists, knots, and rings in proteins: Structural definition of the cyclotide framework

2003

Journal Article

Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotides

Daly, N. L., Clark, R. J. and Craik, D. J. (2003). Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotides. The Journal of Biological Chemistry, 278 (8), 6314-6322. doi: 10.1074/jbc.M210492200

Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotides

2003

Journal Article

Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence

Nicke, Annette, Loughnan, Marion L., Millard, Emma L., Alewood, Paul F., Adams, David J., Daly, Norelle L., Craik, David J. and Lewis, Richard J. (2003). Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. Journal of Biological Chemistry, 278 (5), 3137-3144. doi: 10.1074/jbc.M210280200

Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence

2003

Journal Article

The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP

Lay, Fung T., Schirra, Horst Joachim, Scanlon, Martin J., Anderson, Marilyn A. and Craik, David J. (2003). The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP. Journal of Molecular Biology, 325 (1), 175-188. doi: 10.1016/S0022-2836(02)01103-8

The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP

2003

Journal Article

Diversity in the disulfide folding pathways of cystine knot peptides

Daly, N. L., Clark, R. J., Goransson, U. and Craik, D. J. (2003). Diversity in the disulfide folding pathways of cystine knot peptides. Letters in Peptide Science, 10 (5-6), 523-531. doi: 10.1007/BF02442584

Diversity in the disulfide folding pathways of cystine knot peptides

2003

Journal Article

Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone

Rosengren, K. J., Clark, R. J., Daly, N. L., Goransson, U., Jones, A. and Craik, D. J. (2003). Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. Journal of the American Chemical Society, 125 (41), 12464-12474. doi: 10.1021/JA0367703

Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone