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2021

Journal Article

Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells

Benfield, Aurélie H., Defaus, Sira, Lawrence, Nicole, Chaousis, Stephanie, Condon, Nicholas, Cheneval, Olivier, Huang, Yen-Hua, Chan, Lai Yue, Andreu, David, Craik, David J. and Henriques, Sónia Troeira (2021). Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells. Biochimica et Biophysica Acta - Biomembranes, 1863 (1) 183480, 183480. doi: 10.1016/j.bbamem.2020.183480

Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells

2021

Journal Article

Small cyclic sodium channel inhibitors

Peigneur, Steve, da Costa Oliveira, Cristina, de Sousa Fonseca, Flávia Cristina, McMahon, Kirsten L., Mueller, Alexander, Cheneval, Olivier, Cristina Nogueira Freitas, Ana, Starobova, Hana, Dimitri Gama Duarte, Igor, Craik, David J., Vetter, Irina, de Lima, Maria Elena, Schroeder, Christina I. and Tytgat, Jan (2021). Small cyclic sodium channel inhibitors. Biochemical Pharmacology, 183 114291, 114291. doi: 10.1016/j.bcp.2020.114291

Small cyclic sodium channel inhibitors

2020

Journal Article

Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching

Rehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, Durek, Thomas and Craik, David J. (2020). Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching. Angewandte Chemie, 133 (8) ange.202013584, 4050-4054. doi: 10.1002/ange.202013584

Improved asparaginyl‐ligase‐catalyzed transpeptidation via selective nucleophile quenching

2020

Journal Article

Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermus

Du, Qingdan, Huang, Yen-Hua, Bajpai, Abhishek, Frosig- Jorgensen, Majbrit, Zhao, Guangzu and Craik, David J. (2020). Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermus. Journal of Natural Products, 83 (12), 3736-3743. doi: 10.1021/acs.jnatprod.0c01045

Evaluation of the in vivo aphrodisiac activity of a cyclotide extract from Hybanthus enneaspermus

2020

Journal Article

Make it or break it: plant AEPs on stage in biotechnology

Jackson, Mark A., Nguyen, Linh T. T., Gilding, Edward K., Durek, Thomas and Craik, David J. (2020). Make it or break it: plant AEPs on stage in biotechnology. Biotechnology Advances, 45 107651, 107651. doi: 10.1016/j.biotechadv.2020.107651

Make it or break it: plant AEPs on stage in biotechnology

2020

Journal Article

Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie

Veer, Simon J., White, Andrew M. and Craik, David J. (2020). Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie. Angewandte Chemie, 133 (15), 8128-8151. doi: 10.1002/ange.202006919

Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie

2020

Journal Article

Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology

de Veer, Simon J., White, Andrew M. and Craik, David (2020). Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology. Angewandte Chemie (International Edition), 59 (15), 2-24. doi: 10.1002/anie.202006919

Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology

2020

Journal Article

Front Cover: Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography (ChemBioChem 24/2020)

Handley, Thomas N. G., Wang, Conan K., Harvey, Peta J., Lawrence, Nicole and Craik, David J. (2020). Front Cover: Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography (ChemBioChem 24/2020). ChemBioChem, 21 (24), 3449-3449. doi: 10.1002/cbic.202000778

Front Cover: Cyclotide Structures Revealed by NMR, with a Little Help from X‐ray Crystallography (ChemBioChem 24/2020)

2020

Journal Article

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

Qu, Haiou, Jackson, Mark A., Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2020). Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta, 252 (6) 97, 97. doi: 10.1007/s00425-020-03505-z

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

2020

Journal Article

Safer in vitro drug screening models for melioidosis therapy development

Amiss, Anna S., Webb, Jessica R., Mayo, Mark, Currie, Bart J., Craik, David J., Henriques, Sónia Troeira and Lawrence, Nicole (2020). Safer in vitro drug screening models for melioidosis therapy development. The American journal of tropical medicine and hygiene, 103 (5), 1846-1851. doi: 10.4269/ajtmh.20-0248

Safer in vitro drug screening models for melioidosis therapy development

2020

Journal Article

Hormone-like conopeptides – new tools for pharmaceutical design

Turner, Ashlin, Kaas, Quentin and Craik, David J. (2020). Hormone-like conopeptides – new tools for pharmaceutical design. RSC Medicinal Chemistry, 11 (11), 1235-1251. doi: 10.1039/d0md00173b

Hormone-like conopeptides – new tools for pharmaceutical design

2020

Journal Article

Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors

Huynh, Peter N., Harvey, Peta J., Gajewiak, Joanna, Craik, David J. and Michael McIntosh, J. (2020). Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors. Biochemical Pharmacology, 181 114124, 114124. doi: 10.1016/j.bcp.2020.114124

Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors

2020

Journal Article

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

Malik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2020). Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes. Peptide Science, 113 (4) e24209. doi: 10.1002/pep2.24209

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

2020

Journal Article

Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis, and activity

Peacock, Hayden, Henriques, Sónia Troeira, Benfield, Aurélie H., Elliott, Alysha G., Luo, Jinghui, Luccarelli, James, Nagano, Masanobu, Craik, David J. and Hamilton, Andrew D. (2020). Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis, and activity. ChemMedChem, 15 (20) cmdc.202000474, 1932-1939. doi: 10.1002/cmdc.202000474

Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis, and activity

2020

Journal Article

Histidine-rich defensins from the Solanaceae and Brasicaceae are antifungal and metal binding proteins

Bleackley, Mark R., Vasa, Shaily, Harvey, Peta J., Shafee, Thomas M. A., Kerenga, Bomai K., Soares da Costa, Tatiana P., Craik, David J., Lowe, Rohan G. T. and Anderson, Marilyn A. (2020). Histidine-rich defensins from the Solanaceae and Brasicaceae are antifungal and metal binding proteins. Journal of Fungi, 6 (3) 145, 145-14. doi: 10.3390/jof6030145

Histidine-rich defensins from the Solanaceae and Brasicaceae are antifungal and metal binding proteins

2020

Journal Article

EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste

Tombling, Benjamin J., Wang, Conan K. and Craik, David J. (2020). EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste. Angewandte Chemie, 132 (28) ange.201913809, 11314-11328. doi: 10.1002/ange.201913809

EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste

2020

Journal Article

Exploring the sequence diversity of cyclotides from Vietnamese Viola species

Dang, Tien T., Chan, Lai Y., Huang, Yen-Hua, Nguyen, Linh T. T., Kaas, Quentin, Huynh, Tien and Craik, David J. (2020). Exploring the sequence diversity of cyclotides from Vietnamese Viola species. Journal of Natural Products, 83 (6) acs.jnatprod.9b01218, 1817-1828. doi: 10.1021/acs.jnatprod.9b01218

Exploring the sequence diversity of cyclotides from Vietnamese Viola species

2020

Journal Article

Characterization of synthetic Tf2 as a NaV1.3 selective pharmacological probe

Israel, Mathilde R., Dash, Thomas S., Bothe, Stefanie N., Robinson, Samuel D., Deuis, Jennifer R., Craik, David J., Lampert, Angelika, Vetter, Irina and Durek, Thomas (2020). Characterization of synthetic Tf2 as a NaV1.3 selective pharmacological probe. Biomedicines, 8 (6) 155, 155. doi: 10.3390/biomedicines8060155

Characterization of synthetic Tf2 as a NaV1.3 selective pharmacological probe

2020

Journal Article

Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020)

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020). Angewandte Chemie, 132 (28), 11258-11258. doi: 10.1002/ange.202006713

Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020)

2020

Journal Article

Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)

White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020). Angewandte Chemie International Edition, 59 (28), 11162-11162. doi: 10.1002/anie.202006713

Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)