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2025

Journal Article

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

Abani, O., Abbas, A., Abbas, F., Abbas, J., Abbas, K., Abbas, M., Abbasi, S., Abbass, H., Abbott, A., Abdallah, N., Abdelaziz, A., Abdelfattah, M., Abdelqader, B., Abdul, A., Abdul, B., Abdul, S., Abdul Rasheed, A., Abdulakeem, A., Abdul-Kadir, R., Abdullah, A., Abdulmumeen, A., Abdul-Raheem, R., Abdulshukkoor, N., Abdusamad, K., Abed El Khaleq, Y., Abedalla, M., Abeer Ul Amna, A., Abel, L., Abernethy, K. ... Zuriaga-Alvaro, A. (2025). Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. eClinicalMedicine, 81 103080, 103080. doi: 10.1016/j.eclinm.2025.103080

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

2024

Journal Article

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ

Kiourtis, Christos, Terradas-Terradas, Maria, Gee, Lucy M., May, Stephanie, Georgakopoulou, Anastasia, Collins, Amy L., O’Sullivan, Eoin D., Baird, David P., Hassan, Mohsin, Shaw, Robin, Tan, Ee Hong, Müller, Miryam, Engelmann, Cornelius, Andreola, Fausto, Hsieh, Ya-Ching, Reed, Lee H., Borthwick, Lee A., Nixon, Colin, Clark, William, Hanson, Peter S., Sumpton, David, Mackay, Gillian, Suzuki, Toshiyasu, Najumudeen, Arafath K., Inman, Gareth J., Campbell, Andrew, Barry, Simon T., Quaglia, Alberto, Morris, Christopher M. ... Bird, Thomas G. (2024). Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ. Nature Cell Biology, 26 (12) eaan1230, 2075-2083. doi: 10.1038/s41556-024-01543-3

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ

2024

Journal Article

A comparison of the diagnostic ability of large language models in challenging clinical cases

Khan, Maria Palwasha and O'Sullivan, Eoin Daniel (2024). A comparison of the diagnostic ability of large language models in challenging clinical cases. Frontiers in Artificial Intelligence, 7 1379297, 1379297. doi: 10.3389/frai.2024.1379297

A comparison of the diagnostic ability of large language models in challenging clinical cases

2024

Journal Article

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial

Faust, Saul N, Haynes, Richard, Jones, Christine E, Staplin, Natalie, Whittaker, Elizabeth, Jaki, Thomas, Juszczak, Ed, Spata, Enti, Wan, Mandy, Bamford, Alasdair, Dimitri, Paul, Finn, Adam, Furness, John, Ramanan, Athimalaipet V, Gale, Christopher, Cathie, Katrina, Drysdale, Simon, Bernatoniene, Jolanta, Murray, Clare, Roehr, Charles C, Fleming, Paul, Riordan, Andrew, Bandi, Srini, Jyothish, Deepthi, Evans, Jennifer, Emonts, Marieke, Kelly, Dominic, Pathan, Nazima, Davies, Patrick ... Zuriaga-Alvaro, A. (2024). Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Child and Adolescent Health, 8 (3), 190-200. doi: 10.1016/S2352-4642(23)00316-4

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial

2024

Journal Article

Avacopan as an additional therapeutic intervention to promote renal recovery in severe ANCA-associated vasculitis: A case report

Atrens, Aleks D., Hutton, Holly, O'Sullivan, Eoin, Moore, John and Madhan, Krishan (2024). Avacopan as an additional therapeutic intervention to promote renal recovery in severe ANCA-associated vasculitis: A case report. Nephrology, 29 (2), 105-107. doi: 10.1111/nep.14253

Avacopan as an additional therapeutic intervention to promote renal recovery in severe ANCA-associated vasculitis: A case report

2024

Book Chapter

Nephron Senescence and Mechanisms

Healy, Helen, Kassianos, Andrew J., Ng, Monica S. Y. and O’Sullivan, Eoin D. (2024). Nephron Senescence and Mechanisms. Kidney Disease in the Elderly. (pp. 25-41) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-68460-9_3

Nephron Senescence and Mechanisms

2023

Journal Article

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Abani, O., Abbas, A., Abbas, F., Abbas, J., Abbas, K., Abbas, M., Abbasi, S., Abbass, H., Abbott, A., Abdallah, N., Abdelaziz, A., Abdelfattah, M., Abdelqader, B., Abdul, A., Abdul, B., Abdul, S., Abdul Rasheed, A., Abdulakeem, A., Abdul-Kadir, R., Abdullah, A., Abdulmumeen, A., Abdul-Raheem, R., Abdulshukkoor, N., Abdusamad, K., Abed El Khaleq, Y., Abedalla, M., Abeer Ul Amna, A., Abel, L., Abernethy, K. ... Zuriaga-Alvaro, A. (2023). Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Diabetes and Endocrinology, 11 (12), 905-914. doi: 10.1016/S2213-8587(23)00253-X

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

2023

Journal Article

Do early relapses predict the risk of long-term relapsing disease in an adult and paediatric cohort with MOGAD?

Chen, Bo, Gomez-Figueroa, Enrique, Redenbaugh, Vyanka, Francis, Anna, Satukijchai, Chanjira, Wu, Yan, Messina, Silvia, Sa, Mario, Woodhall, Mark, Robertson, Neil P., Lim, Ming, Wassmer, Evangeline, Kneen, Rachel, Huda, Saif, Blain, Camilla, Halfpenny, Christopher, Hemingway, Cheryl, O'Sullivan, Eoin, Hobart, Jeremy, Fisniku, Leonora K., Martin, Roswell J., Dobson, Ruth, Cooper, Sarah A., Williams, Victoria, Waters, Patrick, Chen, John J., Pittock, Sean J., Ramdas, Sithara, Leite, Maria Isabel ... Palace, Jacqueline (2023). Do early relapses predict the risk of long-term relapsing disease in an adult and paediatric cohort with MOGAD?. Annals of Neurology, 94 (3), 508-517. doi: 10.1002/ana.26731

Do early relapses predict the risk of long-term relapsing disease in an adult and paediatric cohort with MOGAD?

2023

Conference Publication

A family of flare- a case of lupus nephritis associated with SPENDCI syndrome with a sister having similar syndrome

Pagnis, Rachna, Hepburn, Kirsten, O'Sullivan, Eoin and Puri, Priyanka (2023). A family of flare- a case of lupus nephritis associated with SPENDCI syndrome with a sister having similar syndrome. 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4–6 September 2023. Richmond, VIC, Australia: John Wiley & Sons.

A family of flare- a case of lupus nephritis associated with SPENDCI syndrome with a sister having similar syndrome

2023

Conference Publication

Discovery And Validation Of Novel Renal Epithelial Senescence Associated Biomarkers

Baird, David, Reck, Maximilian, Campbell, Ross, O'Sullivan, Eoin, Docherty, Marie-Helena, Cairns, Carolynn, Carvalho, Cyril, Vermeren, Matthieu, Hughes, Jeremy, Mark, Patrick, Denby, Laura, Conway, Bryan, Mylonas, Katie and Ferenbach, David (2023). Discovery And Validation Of Novel Renal Epithelial Senescence Associated Biomarkers. 60th ERA Congress, Milan, Italy, 15-18 June 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ndt/gfad063c_4455

Discovery And Validation Of Novel Renal Epithelial Senescence Associated Biomarkers

2023

Journal Article

Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis

O'Sullivan, Eoin D., Mylonas, Katie J., Xin, Cuiyan, Baird, David P., Carvalho, Cyril, Docherty, Marie-Helena, Campbell, Ross, Matchett, Kylie P., Waddell, Scott H., Walker, Alexander D., Gallagher, Kevin M., Jia, Siyang, Leung, Steve, Laird, Alexander, Wilflingseder, Julia, Willi, Michaela, Reck, Maximilian, Finnie, Sarah, Pisco, Angela, Gordon-Keylock, Sabrina, Medvinsky, Alexander, Boulter, Luke, Henderson, Neil C., Kirschner, Kristina, Chandra, Tamir, Conway, Bryan R., Hughes, Jeremy, Denby, Laura, Bonventre, Joseph V. and Ferenbach, David A. (2023). Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis. Science Translational Medicine, 15 (698) abn0736, eabn0736. doi: 10.1126/scitranslmed.abn0736

Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis

2022

Journal Article

Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis

O'Sullivan, Eoin D., Mylonas, Katie J., Bell, Rachel, Carvalho, Cyril, Baird, David P., Cairns, Carolynn, Gallagher, Kevin M., Campbell, Ross, Docherty, Marie, Laird, Alexander, Henderson, Neil C., Chandra, Tamir, Kirschner, Kristina, Conway, Bryan, Dihazi, Gry H., Zeisberg, Michael, Hughes, Jeremy, Denby, Laura, Dihazi, Hassan and Ferenbach, David A. (2022). Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis. JCI Insight, 7 (22) e154124. doi: 10.1172/jci.insight.154124

Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis

2022

Journal Article

Cognitive bias is a crucial factor in nurses' decision making

O'sullivan, Eoin D. (2022). Cognitive bias is a crucial factor in nurses' decision making. Evidence-Based Nursing, 26 (1), 37-37. doi: 10.1136/ebnurs-2022-103585

Cognitive bias is a crucial factor in nurses' decision making

2022

Journal Article

Covid-19: the government's gaslighting has left vulnerable patients feeling forgotten

O'Sullivan, Eoin D. (2022). Covid-19: the government's gaslighting has left vulnerable patients feeling forgotten. The BMJ (378) o2033. doi: 10.1136/bmj.o2033

Covid-19: the government's gaslighting has left vulnerable patients feeling forgotten

2022

Journal Article

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abdallah, Nabeel, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Basir, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdullah, Abdullah, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Ul-Amna, Abeer, Abernethy, Katrina, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abraham, Miriam ... RECOVERY Collaborative Group (2022). Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399 (10325), 665-676. doi: 10.1016/S0140-6736(22)00163-5

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

2022

Journal Article

Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abdallah, Nabeel, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Basir, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdullah, Abdullah, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Abeer Ul Amna, Abeer Ul Amna, Abernethy, Katrina, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abraham, Miriam ... RECOVERY Collaborative Group (2022). Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399 (10320), 143-151. doi: 10.1016/S0140-6736(21)01825-0

Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

2021

Journal Article

Aging modulates the effects of ischemic injury upon mesenchymal cells within the renal interstitium and microvasculature

Shaw, Isaac W., O'Sullivan, Eoin D., Pisco, Angela O., Borthwick, Gary, Gallagher, Kevin M., Péault, Bruno, Hughes, Jeremy and Ferenbach, David A. (2021). Aging modulates the effects of ischemic injury upon mesenchymal cells within the renal interstitium and microvasculature. Stem Cells Translational Medicine, 10 (8), 1232-1248. doi: 10.1002/sctm.20-0392

Aging modulates the effects of ischemic injury upon mesenchymal cells within the renal interstitium and microvasculature

2021

Journal Article

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abdallah, Nabeel, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdo, David, Abdul, Basir, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdulle, Amina, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Abeer Ul Amna, Abeer Ul Amna, Abernethy, Katrina, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud ... RECOVERY Collaborative Group (2021). Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. The Lancet, 397 (10289), 2049-2059. doi: 10.1016/S0140-6736(21)00897-7

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

2021

Journal Article

Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair

Mylonas, Katie J., O’Sullivan, Eoin D., Humphries, Duncan, Baird, David P., Docherty, Marie-Helena, Neely, Sarah A., Krimpenfort, Paul J., Melk, Anette, Schmitt, Roland, Ferreira-Gonzalez, Sofia, Forbes, Stuart J., Hughes, Jeremy and Ferenbach, David A. (2021). Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair. Science Translational Medicine, 13 (594) eabb0203. doi: 10.1126/scitranslmed.abb0203

Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair

2021

Journal Article

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abdallah, Nabeel, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Basir, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Abeer Ul Amna, Abeer, Abernethy, Katrina, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abraham, Miriam, Abraham, Tizzy ... RECOVERY Collaborative Group (2021). Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 397 (10285), 1637-1645. doi: 10.1016/S0140-6736(21)00676-0

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial