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2015

Journal Article

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015). A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (8), 4689-4694. doi: 10.1128/AAC.00409-15

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

2015

Journal Article

Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?

Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015). Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 (8), 419-424. doi: 10.5301/ijao.5000422

Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?

2015

Journal Article

Does appropriate antibiotic therapy mean only adequate spectrum and timing?

Lipman, Jeffrey and Roberts, Jason (2015). Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 (8), 1773-1774. doi: 10.1097/CCM.0000000000001060

Does appropriate antibiotic therapy mean only adequate spectrum and timing?

2015

Journal Article

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review

Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015). Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 (4), 367-375. doi: 10.1016/j.ijantimicag.2015.06.016

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review

2015

Journal Article

Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration

Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A., Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 46 (1), 39-44. doi: 10.1016/j.ijantimicag.2015.02.014

Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration

2015

Journal Article

Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017

Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis

2015

Journal Article

Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis

Brink, A. J., Richards, G. A., Lautenbach, E. E. G., Rapeport, N., Schillack, V., van Niekerk, L., Lipman, J. and Roberts, J. A. (2015). Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis. International Journal of Antimicrobial Agents, 45 (6), 647-651. doi: 10.1016/j.ijantimicag.2015.01.015

Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis

2015

Journal Article

Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study

Finfer, Simon, Chittock, Dean, Li, Yang, Foster, Denise, Dhingra, Vinay, Bellomo, Rinaldo, Cook, Deborah, Dodek, Peter, Hebert, Paul, Henderson, William, Heyland, Daren, Higgins, Alisa, McArthur, Colin, Mitchell, Imogen, Myburgh, John, Robinson, Bruce, Ronco, Juan, Blair, Deborah, McArthur, Colin, Mitchell, Imogen, Norton, Robyn, Potter, Julie, Chittock, Dean, Dhingra, Vinay, Foster, Denise, Cook, Deborah, Dodek, Peter, Hebert, Paul, Henderson, William ... Wood, Gordon (2015). Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. Intensive Care Medicine, 41 (6), 1037-1047. doi: 10.1007/s00134-015-3757-6

Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study

2015

Journal Article

Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply

Hanrahan, Timothy P., Harlow, Georgina, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply. Critical Care Medicine, 43 (5), E154-E155. doi: 10.1097/CCM.0000000000000952

Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply

2015

Journal Article

How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?

Jamal, Janattul-Ain, Mueller, Bruce A., Choi, Gordon Y. S., Lipman, Jeffrey and Roberts, Jason A. (2015). How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?. Diagnostic Microbiology and Infectious Disease, 82 (1), 92-103. doi: 10.1016/j.diagmicrobio.2015.01.013

How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?

2015

Journal Article

Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

De Waele, J. J., Lipman, J., Akova, M., Bassetti, M. , Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P. , Rello, J. , Rhodes, A. , Udy, A. A. , Starr, T. , Wallis, S. C. and Roberts, J. A. (2015). Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 41 (5), 969-969. doi: 10.1007/s00134-015-3772-7

Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients

2015

Journal Article

Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: Development and evaluation of a simple, standard protocol

Lau, Anna F, Kabir, Masrura, Chen, Sharon C-A, Playford, E. Geoffrey, Marriott, Deborah J, Jones, Michael, Lipman, Jeffrey, McBryde, Emma, Gottlieb, Thomas, Cheung, Winston, Seppelt, Ian, Iredell, Jonathan and Sorrella, Tania C (2015). Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: Development and evaluation of a simple, standard protocol. Journal of Clinical Microbiology, 53 (4), 1324-1330. doi: 10.1128/JCM.03239-14

Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: Development and evaluation of a simple, standard protocol

2015

Journal Article

The Durban World Congress Ethics Round Table IV: Health care professional end-of-life decision making

Joynt, Gavin M., Lipman, Jeffrey, Hartog, Christiane, Guidet, Bertrand, Paruk, Fathima, Feldman, Charles, Kissoon, Niranjan and Sprung, Charles L. (2015). The Durban World Congress Ethics Round Table IV: Health care professional end-of-life decision making. Journal of Critical Care, 30 (2), 224-230. doi: 10.1016/j.jcrc.2014.10.011

The Durban World Congress Ethics Round Table IV: Health care professional end-of-life decision making

2015

Journal Article

A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics

Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 (84) 84, 84. doi: 10.1186/s13054-015-0818-8

A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics

2015

Journal Article

Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients

Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015). Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (3), 1411-1417. doi: 10.1128/AAC.04001-14

Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients

2015

Journal Article

Serum markers of sepsis in burn patients: it takes more to convince! Reply

Paratz, Jennifer D., Lipman, Jeffrey and Boots, Robert J. (2015). Serum markers of sepsis in burn patients: it takes more to convince! Reply. Critical Care Medicine, 43 (3), E101-E101. doi: 10.1097/CCM.0000000000000868

Serum markers of sepsis in burn patients: it takes more to convince! Reply

2015

Journal Article

The impact of hospital and ICU organizational factors on outcome in critically ill patients: results from the Extended Prevalence of Infection in Intensive Care Study

Sakr, Yasser, Moreira, Cora L., Rhodes, Andrew, Ferguson, Niall D., Kleinpell, Ruth, Pickkers, Peter, Kuiper, Michael A., Lipman, Jeffrey, Vincent, Jean-Louis and Extended Prevalence of Infection in Intensive Care Study Investigators (2015). The impact of hospital and ICU organizational factors on outcome in critically ill patients: results from the Extended Prevalence of Infection in Intensive Care Study. Critical Care Medicine, 43 (3), 519-526. doi: 10.1097/CCM.0000000000000754

The impact of hospital and ICU organizational factors on outcome in critically ill patients: results from the Extended Prevalence of Infection in Intensive Care Study

2015

Journal Article

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042

A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans

2015

Journal Article

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015). Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 (33) 33, 1-7. doi: 10.1186/s13054-015-0758-3

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

2015

Journal Article

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015). Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 (2), 528-533. doi: 10.1093/jac/dku413

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?