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2016

Journal Article

Characteristics, treatment and outcomes for all emergency department patients fulfilling criteria for septic shock: a prospective observational study

Williams, Julian M., Greenslade, Jaimi H., Dymond, Chelsea A., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffery (2016). Characteristics, treatment and outcomes for all emergency department patients fulfilling criteria for septic shock: a prospective observational study. European Journal of Emergency Medicine, 25 (2), 1-104. doi: 10.1097/MEJ.0000000000000419

Characteristics, treatment and outcomes for all emergency department patients fulfilling criteria for septic shock: a prospective observational study

2015

Journal Article

The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial

Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015). The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 (12) e0144740, e0144740. doi: 10.1371/journal.pone.0144740

The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial

2015

Journal Article

A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts

McHugh, Leo, Seldon, Therese A., Brandon, Roslyn A., Kirk, James T., Rapisarda, Antony, Sutherland, Allison J., Presneill. Jeffrey J., Venter, Deon J., Lipman, Jeffrey, Thomas, Mervyn R., Klein Klouwenberg, Peter M.C., van Vught, Lonneke, Scicluna, Brendon, Bonten, Marc, Cremer, Olaf L., Schultz, Marcus J., van der Poll, Tom, Yager, Thomas D. and Brandon, Richard B. (2015). A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts. PLoS Medicine, 12 (12) e1001916, e1001916. doi: 10.1371/journal.pmed.1001916

A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts

2015

Journal Article

A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate ... Paul, Sanjoy (2015). A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 (11), 1298-1305. doi: 10.1164/rccm.201505-0857OC

A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis

2015

Journal Article

Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?

Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015). Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 (12), 3178-3183. doi: 10.1093/jac/dkv201

Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?

2015

Journal Article

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015). Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 (9), 563-572. doi: 10.1016/j.medine.2015.07.001

Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos

2015

Journal Article

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015). A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115, 509-514. doi: 10.1016/j.jpba.2015.07.013

A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans

2015

Journal Article

Population pharmacokinetics of fosfomycin in critically ill patients

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015). Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (10), 6471-6476. doi: 10.1128/AAC.01321-15

Population pharmacokinetics of fosfomycin in critically ill patients

2015

Journal Article

To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: The eternal doubt

Wong, Wai-Tat, Choi, Gordon, Gomersall, Charles D. and Lipman, Jeffrey (2015). To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: The eternal doubt. Current Opinion in Pharmacology, 24, 68-78. doi: 10.1016/j.coph.2015.07.003

To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: The eternal doubt

2015

Journal Article

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015). Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 (19), 2585-2595. doi: 10.4155/bio.15.173

Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling

2015

Journal Article

Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill

Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 (5), 412-420. doi: 10.1097/MCC.0000000000000229

Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill

2015

Journal Article

Understanding PK/PD

Roberts, Jason A., Taccone, Fabio Silvio. and Lipman, Jeffrey. (2015). Understanding PK/PD. Intensive Care Medicine, 42 (11), 1797-1800. doi: 10.1007/s00134-015-4032-6

Understanding PK/PD

2015

Journal Article

An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015). An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 (18), 2311-2319. doi: 10.4155/bio.15.143

An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine

2015

Journal Article

Factors associated with vancomycin nephrotoxicity in the critically ill

Hanrahan, T. P., Kotapati, C., Roberts, M. J., Rowland, J., Lipman, J., Roberts, J. A. and Udy, A. (2015). Factors associated with vancomycin nephrotoxicity in the critically ill. Anaesthesia and Intensive Care, 43 (5), 594-599. doi: 10.1177/0310057X1504300507

Factors associated with vancomycin nephrotoxicity in the critically ill

2015

Journal Article

Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion

Hanrahan, Timothy, Whitehouse, Tony, Lipman, Jeffrey and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion. International Journal of Antimicrobial Agents, 46 (3), 249-253. doi: 10.1016/j.ijantimicag.2015.04.013

Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion

2015

Journal Article

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015). The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 (9), 2671-2677. doi: 10.1093/jac/dkv165

The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs

2015

Journal Article

Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?

Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015). Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 (8), 419-424. doi: 10.5301/ijao.5000422

Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?

2015

Journal Article

Does appropriate antibiotic therapy mean only adequate spectrum and timing?

Lipman, Jeffrey and Roberts, Jason (2015). Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 (8), 1773-1774. doi: 10.1097/CCM.0000000000001060

Does appropriate antibiotic therapy mean only adequate spectrum and timing?

2015

Journal Article

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015). A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (8), 4689-4694. doi: 10.1128/AAC.00409-15

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

2015

Journal Article

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review

Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015). Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 (4), 367-375. doi: 10.1016/j.ijantimicag.2015.06.016

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review