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2014

Journal Article

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014). Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 (10), 2797-2803. doi: 10.1093/jac/dku195

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

2014

Journal Article

Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels

Hanberger, Hakan, Antonelli, Massimo, Holmbom, Martin, Lipman, Jeffrey, Pickkers, Peter, Leone, Marc, Rello, Jordi, Sakr, Yasser, Walther, Sten M., Vanhems, Philippe, Vincent, Jean-Louis, for the EPIC II Group of Investigators and Koulenti, D. (2014). Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels. BMC Infectious Diseases, 14 (513) 513. doi: 10.1186/1471-2334-14-513

Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels

2014

Journal Article

Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 (6), 907-908. doi: 10.1093/cid/ciu403

Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al

2014

Journal Article

Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections

Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014). Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 (5), 409-415. doi: 10.1016/j.ijantimicag.2014.07.001

Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections

2014

Journal Article

Infections and use of antibiotics in patients admitted for severe acute pancreatitis: Data from the epic II study

De Waele, Jan J., Rello, Jordi, Anzueto, Antonio, Moreno, Rui, Lipman, Jeffrey, Sakr, Yasser, Pickkers, Peter, Leone, Marc, Ferguson, Andrew, Oud, Lavi and Vincent, Jean-Louis (2014). Infections and use of antibiotics in patients admitted for severe acute pancreatitis: Data from the epic II study. Surgical Infections, 15 (4), 394-398. doi: 10.1089/sur.2012.228

Infections and use of antibiotics in patients admitted for severe acute pancreatitis: Data from the epic II study

2014

Journal Article

The authors reply

Udy, Andrew A., Baptista, João P., Lim, Noelle L., Joynt, Gavin M., Jarrett, Paul, Boots, Robert J. and Lipman, Jeffrey (2014). The authors reply. Critical Care Medicine, 42 (8), e602-e603. doi: 10.1097/CCM.0000000000000465

The authors reply

2014

Journal Article

Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome

De Waele, Jan, Lipman, Jeffrey, Sakr, Yasser, Marshall, John C., Vanhems, Philippe, Barrera Groba, Casiano, Leone, Marc and Vincent, Jean-Louis (2014). Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome. BMC Infectious Diseases, 14 (420) 420, 1-17. doi: 10.1186/1471-2334-14-420

Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome

2014

Journal Article

The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens

Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 (7), 1640-1650. doi: 10.1097/CCM.0000000000000317

The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens

2014

Journal Article

Burn resuscitation - hourly urine output vs alternative endpoints: a systematic review

Paratz, Jennifer D., Stockton, Kellie, Paratz, Elizabeth D., Blot, Stijn, Muller, Michael, Lipman, Jeffrey and Boots, Robert J. (2014). Burn resuscitation - hourly urine output vs alternative endpoints: a systematic review. Shock, 42 (4), 295-306. doi: 10.1097/SHK.0000000000000204

Burn resuscitation - hourly urine output vs alternative endpoints: a systematic review

2014

Journal Article

Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?

Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 (6), 572-573. doi: 10.1016/j.ijantimicag.2014.03.001

Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?

2014

Journal Article

Randomised controlled trials: the long hard climb to the summit - is there another way in the 21st century?

Dulhunty, Joel M., Starr, Therese, Bellomo, Rinaldo and Lipman, Jeffrey (2014). Randomised controlled trials: the long hard climb to the summit - is there another way in the 21st century?. Critical Care and Resuscitation, 16 (2), 87-89.

Randomised controlled trials: the long hard climb to the summit - is there another way in the 21st century?

2014

Journal Article

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014). Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 (3) R99, 1-11. doi: 10.1186/cc13874

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

2014

Journal Article

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 (5) dku564, 1495-1502. doi: 10.1093/jac/dku564

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

2014

Journal Article

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

2014

Journal Article

The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?

Blot,Stijn, Lipman, Jeffrey, Roberts, Darren M. and Roberts, Jason A (2014). The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?. Diagnostic Microbiology and Infectious Disease, 79 (1), 77-84. doi: 10.1016/j.diagmicrobio.2014.01.015

The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?

2014

Journal Article

Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit

Vincent, Jean-Louis, Marshall, John C., Namendys-Silva, Silvo A., Francois, Bruno, Martin-Loeches, Ignacio, Lipman, Jeffrey, Reinhart, Konrad, Antonelli, Massimo, Pickkers, Peter, Njimi, Hassane, Jimenez, Edgar and Sakr, Yasser (2014). Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit. The Lancet Respiratory Medicine, 2 (5), 380-386. doi: 10.1016/S2213-2600(14)70061-X

Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit

2014

Journal Article

DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 (8), 1072-1083. doi: 10.1093/cid/ciu027

DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?

2014

Journal Article

Calorie intake and patient outcomes in severe acute kidney injury: Findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial

Bellomo, Rinaldo, Cass, Alan, Cole, Louise, Finfer, Simon, Gallagher, Martin, Lee, Janne, Lo, Serigne, McArthur, Colin, McGuinness, Shay, Myburgh, John, Norton, Robyn, Scheinkestel, Carlos, The RENAL Study Investigators, Lipman, Jeffrey and Boots, Robert (2014). Calorie intake and patient outcomes in severe acute kidney injury: Findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial. Critical Care, 18 (2) R45, 1-11. doi: 10.1186/cc13767

Calorie intake and patient outcomes in severe acute kidney injury: Findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial

2014

Journal Article

Seated and semi-recumbent positioning of the ventilated intensive care patient - effect on gas exchange, respiratory mechanics and hemodynamics

Thomas, Peter, Paratz, Jennifer and Lipman, Jeffrey (2014). Seated and semi-recumbent positioning of the ventilated intensive care patient - effect on gas exchange, respiratory mechanics and hemodynamics. Heart and Lung: Journal of Acute and Critical Care, 43 (2), 105-111. doi: 10.1016/j.hrtlng.2013.11.011

Seated and semi-recumbent positioning of the ventilated intensive care patient - effect on gas exchange, respiratory mechanics and hemodynamics

2014

Journal Article

Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study

Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014). Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 (5), 423-430. doi: 10.1016/j.ijantimicag.2014.01.023

Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study