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2015

Journal Article

Contrasting association of circulating sCD14 with insulin sensitivity in non-obese and morbidly obese subjects

de Courten, Barbora, Moreno-Navarrete, Jose Maria, Lyons, Jasmine, Soldatos, Georgia, de Courten, Maximilian, Dougherty, Sonia, Forbes, Josephine and Fernandez-Real, Jose Manuel (2015). Contrasting association of circulating sCD14 with insulin sensitivity in non-obese and morbidly obese subjects. Molecular Nutrition and Food Research, 60 (1), 103-109. doi: 10.1002/mnfr.201500102

Contrasting association of circulating sCD14 with insulin sensitivity in non-obese and morbidly obese subjects

2014

Journal Article

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

Hasnain, Sumaira Z., Borg, Danielle J., Harcourt, Brooke E., Tong, Hui, Sheng, Yonghua H., Ng, Choa Ping, Das, Indrajit, Wang, Ran, Chen, Alice C.-H., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathan P., Forbes, Josephine M., Prins, Johannes B. and McGuckin, Michael A. (2014). Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nature Medicine, 20 (12), 1417-1426. doi: 10.1038/nm.3705

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

2014

Journal Article

Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy

Thallas‐Bonke, Vicki, Jha, Jay C., Gray, Stephen P., Barit, David, Haller, Hermann, Schmidt, Harald H.H.W., Coughlan, Melinda T., Cooper, Mark E., Forbes, Josephine M. and Jandeleit‐Dahm, Karin A.M. (2014). Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy. Physiological Reports, 2 (11) e12192, e12192.1-e12192.13. doi: 10.14814/phy2.12192

Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy

2014

Conference Publication

Manipulation of dietary advanced glycation end-product content influences the progression of non-alcoholic fatty liver disease (NAFLD)

Leung, C., Herath, C. B., Zhiyuan, J., Leong, T., Forbes, J. M. and Angus, P. W. (2014). Manipulation of dietary advanced glycation end-product content influences the progression of non-alcoholic fatty liver disease (NAFLD). HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/jgh.12794

Manipulation of dietary advanced glycation end-product content influences the progression of non-alcoholic fatty liver disease (NAFLD)

2014

Journal Article

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes

Tesch, Greg, Sourris, Karly C., Summers, Shaun A., McCarthy, Domenica, Ward, Micheal S., Borg, Danielle J., Gallo, Linda A., Fotheringham, Amelia K., Pettit, Allison R., Yap, Felicia Y. T., Harcourt, Brooke E., Tan, Adeline L. Y., Kausman, Joshua Y., Nikolic-Paterson, David, Kitching, Arthur R. and Forbes, Josephine M. (2014). Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes. Diabetologia, 57 (9), 1977-1985. doi: 10.1007/s00125-014-3291-z

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes

2014

Journal Article

Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy?

Zhuang, Aowen and Forbes, Josephine M. (2014). Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy?. Journal of Endocrinology, 222 (3), R97-R111. doi: 10.1530/JOE-13-0517

Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy?

2014

Journal Article

Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy

Fukami, Kei, Yamagishi, Sho-ichi, Coughlan, Melinda T., Harcourt, Brooke E., Kantharidis, Phillip, Thallas-Bonke, Vicki, Okuda, Seiya, Cooper, Mark E. and Forbes, Josephine M. (2014). Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy. Diabetology and Metabolic Syndrome, 6 (1) 86, 86. doi: 10.1186/1758-5996-6-86

Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy

2014

Journal Article

SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial

Rossi, Megan, Johnson, David W., Morrison, Mark, Pascoe, Elaine, Coombes, Jeff S., Forbes, Josephine M., McWhinney, Brett C., Ungerer, Jacobus P. J., Dimeski, Goce and Campbell, Katrina L. (2014). SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial. BMC Nephrology, 15 (1) 106, 106.1-106.10. doi: 10.1186/1471-2369-15-106

SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial

2014

Journal Article

Circulating concentrations of soluble receptor for AGE are associated with age and AGER gene polymorphisms in children with newly diagnosed type 1 diabetes

Salonen, Kirsi M., Ryhanen, Samppa J., Forbes, Josephine M., Harkonen, Taina, Ilonen, Jorma, Laine, Antti-Pekka, Groop, Per-Henrik and Knip, Mikael (2014). Circulating concentrations of soluble receptor for AGE are associated with age and AGER gene polymorphisms in children with newly diagnosed type 1 diabetes. Diabetes Care, 37 (7), 1975-1981. doi: 10.2337/dc13-3049

Circulating concentrations of soluble receptor for AGE are associated with age and AGER gene polymorphisms in children with newly diagnosed type 1 diabetes

2014

Journal Article

Dietary glycotoxins exacerbate progression of experimental fatty liver disease

Leung, Christopher, Herath, Chandana B., Jia, Zhiyuan, Goodwin, Michelle, Mak, Kai Yan, Watt, Matthew J., Forbes, Josephine M. and Angus, Peter W. (2014). Dietary glycotoxins exacerbate progression of experimental fatty liver disease. Journal of Hepatology, 60 (4), 832-838. doi: 10.1016/j.jhep.2013.11.033

Dietary glycotoxins exacerbate progression of experimental fatty liver disease

2014

Conference Publication

Glyoxalase-1 Inhibition Leads to Podocyte Insulin Resistance and Features Resembling Diabetic Kidney Disease

Gallo, Linda A., Ward, Micheal S., Harcourt, Brooke E., Fotheringham, Amelia K., McCarthy, Domenica A., Penfold, Sally A. and Forbes, Josephine M. (2014). Glyoxalase-1 Inhibition Leads to Podocyte Insulin Resistance and Features Resembling Diabetic Kidney Disease. 14th Asian Pacific Congress of Nephrology, Tokyo, Japan, 14-17 May 2014. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.12236

Glyoxalase-1 Inhibition Leads to Podocyte Insulin Resistance and Features Resembling Diabetic Kidney Disease

2014

Conference Publication

Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice

Tesch, G. H., Sourris, K. C., Summers, S. A., Mccarthy, D., Ward, M. S., Borg, D. J., Gallo, L. A., Fotheringham, A. K., Pettit, A., Yap, F. Y. T., Harcourt, B. E., Tan, A. L. Y., Kausman, J. Y., Nikolic-Paterson, D. J., Kitching, A. R. and Forbes, J. M. (2014). Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301

Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice

2014

Conference Publication

Mitochondrial targeting of superoxide by Mitoq improves metabolic renal dysfunction

Ward, M. S., Flemming, N. B., Gallo, L. A., Fotheringham, A., Gobe, G., Vesey, D. and Forbes, J. M. (2014). Mitochondrial targeting of superoxide by Mitoq improves metabolic renal dysfunction. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301

Mitochondrial targeting of superoxide by Mitoq improves metabolic renal dysfunction

2014

Journal Article

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, Karly C., Lyons, Jasmine G., Dougherty, Sonia L., Chand, Vibhasha, Straznicky, Nora E., Schlaich, Markus P., Grima, Mariee T., Cooper, Mark E., Kingwell, Bronwyn A., de Courten, Maximilian P. J., Forbes, Josephine M. and de Courten, Barbora (2014). Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure. Clinical Chemistry and Laboratory Medicine, 52 (1), 129-138. doi: 10.1515/cclm-2012-0850

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

2014

Conference Publication

Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes

Leung, C., Fotheringham, A. K., Zhuang, A., Borg, D. J., Ward, M. S., Coughlan, M. T., Mccarthy, D. A., Gallo, L. A., Harcourt, B. E. and Forbes, J. M. (2014). Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12302

Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes

2014

Conference Publication

Ager1 overexpression in glomerular podocytes results in renal disease which is exacerbated by diabetes

Zhuang, A., Sourris, K. C, Harcourt, B. E, Penfold, S. A., Fotheringham, A. K., McCarthy, D., Schulz, B. and Forbes, J. M. (2014). Ager1 overexpression in glomerular podocytes results in renal disease which is exacerbated by diabetes. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne VIC, Australia, 25 - 27 August 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301

Ager1 overexpression in glomerular podocytes results in renal disease which is exacerbated by diabetes

2013

Conference Publication

Report on ISN Forefronts, Melbourne, Australia, 4-7 October 2012: tubulointerstitial disease in diabetic nephropathy

Forbes, Josephine M., Harris, David C. H. and Cooper, Mark E. (2013). Report on ISN Forefronts, Melbourne, Australia, 4-7 October 2012: tubulointerstitial disease in diabetic nephropathy. New York, NY, United States: Elsevier. doi: 10.1038/ki.2013.89

Report on ISN Forefronts, Melbourne, Australia, 4-7 October 2012: tubulointerstitial disease in diabetic nephropathy

2013

Journal Article

Dietary advanced glycation end products as an environmental contributor to type 1 diabetes

Borg, Danielle J. and Forbes, Josephine M. (2013). Dietary advanced glycation end products as an environmental contributor to type 1 diabetes. IMARS Highlights, 8 (5), 21-22.

Dietary advanced glycation end products as an environmental contributor to type 1 diabetes

2013

Journal Article

Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes

Penno, Megan A. S., Couper, Jennifer J., Craig, Maria E., Colman, Peter G., Rawlinson, William D., Cotterill, Andrew M., Jones, Timothy W., Harrison, Leonard C., ENDIA Study Group and Forbes, Josephine M. (2013). Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes. BMC Pediatrics, 13 (1) 124, 124.1-124.15. doi: 10.1186/1471-2431-13-124

Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes

2013

Journal Article

Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease

Forbes, Josephine M., Ke, Bi-Xia, Tuong-Vi Nguyen, Henstridge, Darren C., Penfold, Sally A., Laskowski, Adrienne, Sourris, Karly C., Groschner, Lukas N., Cooper, Mark E., Thorburn, David R. and Coughlan, Melinda T. (2013). Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease. Antioxidants and Redox Signaling, 19 (4), 331-343. doi: 10.1089/ars.2012.4719

Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease