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2013

Journal Article

Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease

Forbes, Josephine M., Ke, Bi-Xia, Tuong-Vi Nguyen, Henstridge, Darren C., Penfold, Sally A., Laskowski, Adrienne, Sourris, Karly C., Groschner, Lukas N., Cooper, Mark E., Thorburn, David R. and Coughlan, Melinda T. (2013). Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease. Antioxidants and Redox Signaling, 19 (4), 331-343. doi: 10.1089/ars.2012.4719

Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease

2013

Journal Article

Effects of high-density lipoprotein elevation with cholesteryl ester transfer protein inhibition on insulin secretion

Siebel, Andrew L., Natoli, Alaina K., Yap, Felicia Y. T., Carey, Andrew L., Reddy-Luthmoodoo, Medini, Sviridov, Dmitri, Weber, Chek Ing Kiu, Meneses-Lorente, Georgina, Maugeais, Cyrille, Forbes, Josephine M. and Kingwell, Bronwyn A. (2013). Effects of high-density lipoprotein elevation with cholesteryl ester transfer protein inhibition on insulin secretion. Circulation Research, 113 (2), 167-175. doi: 10.1161/CIRCRESAHA.113.300689

Effects of high-density lipoprotein elevation with cholesteryl ester transfer protein inhibition on insulin secretion

2013

Journal Article

Glucose homeostasis can be differentially modulated by varying individual components of a western diet

Forbes, Josephine M., Cowan, Samantha P., Andrikopoulos, Sofianos, Morley, Amy L., Ward, Leigh C., Walker, Karen Z., Cooper, Mark E. and Coughlan, Melinda T. (2013). Glucose homeostasis can be differentially modulated by varying individual components of a western diet. Journal of Nutritional Biochemistry, 24 (7), 1251-1257. doi: 10.1016/j.jnutbio.2012.09.009

Glucose homeostasis can be differentially modulated by varying individual components of a western diet

2013

Conference Publication

Type 2 diabetes mellitus and brain atrophy - the role of advanced glycation end-products

Moran, C., Muench, G., Beare, R., Blizzard, L., Venn, A., Phan, T., Forbes, J. and Srikanth, V (2013). Type 2 diabetes mellitus and brain atrophy - the role of advanced glycation end-products. HOBOKEN: WILEY-BLACKWELL.

Type 2 diabetes mellitus and brain atrophy - the role of advanced glycation end-products

2013

Journal Article

Insulin infusion reduces hepatocyte growth factor in lean humans

de Courten, Barbora, de Courten, Maximilian P. J., Dougherty, Sonia, Forbes, Josephine M., Potts, Jenna R. and Considine, Robert V. (2013). Insulin infusion reduces hepatocyte growth factor in lean humans. Metabolism: Clinical and Experimental, 62 (5), 647-650. doi: 10.1016/j.metabol.2012.10.013

Insulin infusion reduces hepatocyte growth factor in lean humans

2013

Journal Article

Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells-Renoprotection in Diabetic Nephropathy?

Panchapakesan, Usha, Pegg, Kate, Gross, Simon, Komala, Muralikrishna Gangadharan, Mudaliar, Harshini, Forbes, Josephine, Pollock, Carol and Mather, Amanda (2013). Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells-Renoprotection in Diabetic Nephropathy?. PLoS One, 8 (2) e54442, e54442.1-e54442.8. doi: 10.1371/journal.pone.0054442

Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells-Renoprotection in Diabetic Nephropathy?

2013

Journal Article

Advanced glycation end products augment experimental hepatic fibrosis

Goodwin, Michelle, Herath, Chandana, Jia, Zhiyuan, Leung, Chris, Coughlan, Melinda T., Forbes, Josephine and Angus, Peter (2013). Advanced glycation end products augment experimental hepatic fibrosis. Journal of Gastroenterology and Hepatology, 28 (2), 369-376. doi: 10.1111/jgh.12042

Advanced glycation end products augment experimental hepatic fibrosis

2013

Journal Article

Mechanisms of diabetic complications

Forbes, Josephine M. and Cooper, Mark E. (2013). Mechanisms of diabetic complications. Physiological Reviews, 93 (1), 137-188. doi: 10.1152/physrev.00045.2011

Mechanisms of diabetic complications

2013

Journal Article

Coming full circle in diabetes mellitus: From complications to initiation

Harcourt, Brooke E., Penfold, Sally A. and Forbes, Josephine M. (2013). Coming full circle in diabetes mellitus: From complications to initiation. Nature Reviews Endocrinology, 9 (2), 113-123. doi: 10.1038/nrendo.2012.236

Coming full circle in diabetes mellitus: From complications to initiation

2013

Journal Article

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, Josephine M., Sourris, Karly C., de Courten, Maximilian P. J., Dougherty, Sonia L., Chand, Vibhasha, Lyons, Jasmine G., Bertovic, David, Coughlan, Melinda T., Schlaich, Markus P., Soldatos, Georgia, Cooper, Mark E., Straznicky, Nora E., Kingwell, Bronwyn A. and de Courten, Barbora (2013). Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects. Amino Acids, 46 (2), 321-326. doi: 10.1007/s00726-013-1542-9

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

2013

Journal Article

Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content.

Thallas-Bonke, Vicki, Coughlan, Melinda T, Tan, Adeline LY, Harcourt, Brooke E, Morgan, Philip E, Davies, Michael J, Bach, Leon A, Cooper, Mark E and Forbes, Josephine M (2013). Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content.. Nephrology (Carlton, Vic.), 18 (1), 47-56. doi: 10.1111/j.1440-1797.2012.01665.x

Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content.

2013

Journal Article

Brain atrophy in type 2 diabetes: regional distribution and influence on cognition

Moran, Chris, Phan, Thanh G., Chen, Jian, Blizzard, Leigh, Beare, Richard, Venn, Alison, Munch, Gerald, Wood, Amanda G., Forbes, Josephine, Greenaway, Timothy M., Pearson, Susan and Srikanth, Velandai (2013). Brain atrophy in type 2 diabetes: regional distribution and influence on cognition. Diabetes Care, 36 (12), 4036-4042. doi: 10.2337/dc13-0143

Brain atrophy in type 2 diabetes: regional distribution and influence on cognition

2013

Conference Publication

Oligosaccharyltransferase-48 as a Novel Mediator of Chronic Kidney Disease in Diabetes

Zhuang, A., Harcourt, B., Sourris, K., Penfold, S., Ward, M., Fotheringham, A., Thorn, P. and Forbes, J. (2013). Oligosaccharyltransferase-48 as a Novel Mediator of Chronic Kidney Disease in Diabetes. WILEY-BLACKWELL.

Oligosaccharyltransferase-48 as a Novel Mediator of Chronic Kidney Disease in Diabetes

2013

Conference Publication

Methylglyoxal induced insulin resistance in podocytes contributes to diabetic kidney disease

Gallo, L. A., Harcourt, B. E., Fotheringham, A. K., McCarthy, D., Penfold, S. A. and Forbes, J. M. (2013). Methylglyoxal induced insulin resistance in podocytes contributes to diabetic kidney disease. 49th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, 23 -27 September 2013. Heidelberg, Germany: Springer. doi: 10.1007/s00125-013-3012-z

Methylglyoxal induced insulin resistance in podocytes contributes to diabetic kidney disease

2013

Journal Article

Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease

Ward, Micheal S., Fortheringham, Amelia K., Cooper, Mark E . and Forbes, Josephine M. (2013). Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease. Current Opinion in Pharmacology, 13 (4), 654-661. doi: 10.1016/j.coph.2013.06.009

Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease

2013

Conference Publication

Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner

Borg, D. J., Yap, F. Y. T., Fotheringham, A. K., Harcourt, B. E., McCarthy, D., Ward, M., Slattery, R., Coughlan, M. T., Kantharidis, P. and Forbes, J. M. (2013). Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner. 49th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, 23 -27 September 2013. Heidelberg, Germany: Springer. doi: 10.1007/s00125-013-3012-z

Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner

2013

Journal Article

Methylglyoxal, cognitive function and cerebral atrophy in older people

Srikanth, Velandai, Westcott, Bernadette, Forbes, Josephine, Phan, Thanh G., Beare, Richard, Venn, Alison, Pearson, Sue, Greenaway, Tim, Parameswaran, Venkat and Muench, Gerald (2013). Methylglyoxal, cognitive function and cerebral atrophy in older people. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 68 (1), 68-73. doi: 10.1093/gerona/gls100

Methylglyoxal, cognitive function and cerebral atrophy in older people

2012

Journal Article

Erratum: methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy (Nature Medicine (2012) 18 (926-933))

Bierhaus, Angelika, Fleming, Thomas, Stoyanov, Stoyan, Leffler, Andreas, Babes, Alexandru, Neacsu, Cristian, Sauer, Susanne K., Eberhardt, Mirjam, Schnölzer, Martina, Lasischka, Felix, Neuhuber, Winfried L., Kichko, Tatjana I., Konrade, Ilze, Elvert, Ralf, Mier, Walter, Pirags, Valdis, Lukic, Ivan K., Morcos, Michael, Dehmer, Thomas, Rabbani, Naila, Thornalley, Paul J., Edelstein, Diane, Nau, Carla, Forbes, Josephine, Humpert, Per M., Schwaninger, Markus, Ziegler, Dan, Stern, David M., Cooper, Mark E. ... Nawroth, Peter P. (2012). Erratum: methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy (Nature Medicine (2012) 18 (926-933)). Nature Medicine, 18 (9), 1445-1445. doi: 10.1038/nm0912-1445c

Erratum: methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy (Nature Medicine (2012) 18 (926-933))

2012

Journal Article

Advanced glycation end-products (AGEs) and functionality of reverse cholesterol transport in patients with type 2 diabetes and in mouse models

Low, H., Hoang, A., Forbes, J., Thomas, M., Lyons, J. G., Nestel, P., Bach, L. A. and Sviridov, D. (2012). Advanced glycation end-products (AGEs) and functionality of reverse cholesterol transport in patients with type 2 diabetes and in mouse models. Diabetologia, 55 (9), 2513-2521. doi: 10.1007/s00125-012-2570-9

Advanced glycation end-products (AGEs) and functionality of reverse cholesterol transport in patients with type 2 diabetes and in mouse models

2012

Journal Article

Methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

Bierhaus, Angelika, Fleming, Thomas, Stoyanov, Stoyan, Leffler, Andreas, Babes, Alexandru, Neacsu, Cristian, Sauer, Susanne K., Eberhardt, Mirjam, Schnoelzer, Martina, Lasischka, Felix, Neuhuber, Winfried L., Kichko, Tatjana I., Konrade, Ilze, Elvert, Ralf, Mier, Walter, Pirags, Valdis, Lukic, Ivan K., Morcos, Michael, Dehmer, Thomas, Rabbani, Naila, Thornalley, Paul J., Edelstein, Diane, Nau, Carla, Forbes, Josephine, Humpert, Per M., Schwaninger, Markus, Ziegler, Dan, Stern, David M., Cooper, Mark E. ... Nawroth, Peter P. (2012). Methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nature Medicine, 18 (6), 926-933. doi: 10.1038/nm.2750

Methylglyoxal modification of Na v 1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy