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2018

Journal Article

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Kondrashova, Olga, Topp, Monique, Nesic, Ksenija, Lieschke, Elizabeth, Ho, Gwo-Yaw, Harrell, Maria I., Zapparoli, Giada V., Hadley, Alison, Holian, Robert, Boehm, Emma, Heong, Valerie, Sanij, Elaine, Pearson, Richard B., Krais, John J., Johnson, Neil, McNally, Orla, Ananda, Sumitra, Alsop, Kathryn, Hutt, Karla J., Kaufmann, Scott H., Lin, Kevin K., Harding, Thomas C., Traficante, Nadia, Chenevix-Trench, G., Green, A., Webb, P., Gertig, D., Fereday, S., Moore, S. ... Australian Ovarian Cancer Study (AOCS) (2018). Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. Nature Communications, 9 (1) 3970, 3970. doi: 10.1038/s41467-018-05564-z

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

2018

Journal Article

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

McCart Reed, Amy E., Kutasovic, Jamie R., Nones, Katia, Saunus, Jodi M., Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E., Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne Marie, David Clouston, D., Porter, Alan, Evans, Elizabeth, Pearson, John V., Chenevix-Trench, Georgia, Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2018). Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology. The Journal of Pathology, 244 (4), 460-468. doi: 10.1002/path.5040

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

2018

Journal Article

MyD88 and TLR4 expression in epithelial ovarian cancer

Block, Matthew S., Vierkant, Robert A., Rambau, Peter F., Winham, Stacey J., Wagner, Philipp, Traficante, Nadia, Tołoczko, Aleksandra, Tiezzi, Daniel G., Taran, Florin Andrei, Sinn, Peter, Sieh, Weiva, Sharma, Raghwa, Rothstein, Joseph H., Ramón y Cajal, Teresa, Paz-Ares, Luis, Oszurek, Oleg, Orsulic, Sandra, Ness, Roberta B., Nelson, Gregg, Modugno, Francesmary, Menkiszak, Janusz, McGuire, Valerie, McCauley, Bryan M., Mack, Marie, Lubiński, Jan, Longacre, Teri A., Li, Zheng, Lester, Jenny, Kennedy, Catherine J. ... Goode, Ellen L. (2018). MyD88 and TLR4 expression in epithelial ovarian cancer. Mayo Clinic Proceedings, 93 (3), 307-320. doi: 10.1016/j.mayocp.2017.10.023

MyD88 and TLR4 expression in epithelial ovarian cancer

2017

Journal Article

Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features

Hendry, Shona, Pang, Jia-Min B., Byrne, David J., Lakhani, Sunil R., Cummings, Margaret C., Campbell, Ian G., Mann, G. Bruce, Gorringe, Kylie L. and Fox, Stephen B. (2017). Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features. Clinical Cancer Research, 23 (17), 5210-5217. doi: 10.1158/1078-0432.CCR-17-0743

Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features

2017

Journal Article

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer

Pang, Jia-Min B., Savas, Peter, Fellowes, Andrew P., Arnau, Gisela Mir, Kader, Tanjina, Vedururu, Ravikiran, Hewitt, Chelsee, Takano, Elena A., Byrne, David J., hoong, David Y. H., Millar, Ewan K. A., Lee, C. Soon, O'Toole, Sandra A., Lakhani, Sunil R., Cummings, Margaret C., Mann, G. Bruce, Campbell, Ian G., Dobrovic, Alexander, Loi, Sherene, Gorringe, Kylie L. and Fox, Stephen B. (2017). Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer. Modern Pathology, 30 (7), 952-963. doi: 10.1038/modpathol.2017.21

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer

2017

Journal Article

PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers

Packer, Leisl M., Geng, Xinyan, Bonazzi, Vanessa F., Ju, Robert J., Mahon, Clare E., Cummings, Margaret C., Stephenson, Sally-Anne and Pollock, Pamela M. (2017). PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers. Molecular Cancer Therapeutics, 16 (4), 637-648. doi: 10.1158/1535-7163.MCT-16-0415

PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers

2017

Journal Article

Technical proficiency in cytopathology: assessment through external quality assurance

Cummings, M. C., Greaves, J., Shukor, R. A., Perkins, G. and Ross, J. (2017). Technical proficiency in cytopathology: assessment through external quality assurance. Cytopathology, 28 (2), 149-156. doi: 10.1111/cyt.12373

Technical proficiency in cytopathology: assessment through external quality assurance

2016

Journal Article

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer

Field, Sarah, Uyttenhove, Catherine, Stroobant, Vincent, Cheou, Paméla, Coutelier, Jean-Paul, Simpson, Peter T., Cummings, Margaret C., Saunus, Jodi M., Reid, Lynne E., Kutasovic, Jamie R., McNicol, Anne Marie, Kim, Ba Reun, Kim, Jae Ho, Lakhani, Sunil R., Neville, A. Munro, Van Snick, Jacques and Jat, Parmjit S. (2016). Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer. International Journal of Cancer, 138 (8), 1959-1970. doi: 10.1002/ijc.29946

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer

2016

Book Chapter

Future role of molecular profiling in small breast samples and personalized medicine

Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-26291-8

Future role of molecular profiling in small breast samples and personalized medicine

2016

Journal Article

RAD51B in familial breast cancer

Pelttari, Liisa M., Khan, Sofia, Vuorela, Mikko, Kiiski, Johanna I., Vilske, Sara, Nevanlinna, Viivi, Ranta, Salla, Schleutker, Johanna, Winqvist, Robert, Kallioniemi, Anne, Dörk, Thilo, Bogdanova, Natalia V., Figueroa, Jonine, Pharoah, Paul D. P., Schmidt, Marjanka K., Dunning, Alison M., García-Closas, Montserrat, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Hopper, John L., Southey, Melissa C., Rosenberg, Efraim H., Fasching, Peter A., Beckmann, Matthias W., Peto, Julian, Dos-Santos-silva, Isabel, Sawyer, Elinor J. ... Zeps, N. (2016). RAD51B in familial breast cancer. PLoS One, 11 (5) e0153788, e0153788. doi: 10.1371/journal.pone.0153788

RAD51B in familial breast cancer

2016

Book Chapter

Future role of molecular profiling in small breast samples and personalised medicine

Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalised medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-26291-8_23

Future role of molecular profiling in small breast samples and personalised medicine

2015

Journal Article

Lynch syndrome and cervical cancer

Antill, Yoland C., Dowty, James G., Win, Aung Ko, Thompson, Tina, Walsh, Michael D., Cummings, Margaret C., Gallinger, Steven, Lindor, Noralane M., Le Marchand, Loic, Hopper, John L., Newcomb, Polly A., Haile, Robert W., Church, James, Tucker, Katherine M., Buchanan, Daniel D., Young, Joanne P., Winship, Ingrid M. and Jenkins, Mark A. (2015). Lynch syndrome and cervical cancer. International Journal of Cancer, 137 (11), 2757-2761. doi: 10.1002/ijc.29641

Lynch syndrome and cervical cancer

2015

Journal Article

Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significance

Saunus, Jodi M., Quinn, MIchael C. J., Patch, Ann-Marie, Pearson, John V., Bailey, Peter J., Nones, Katia, McCart Reed, Amy E., Miller, David, Peter J. Wilson, Al-Ejeh, Fares, Mariasegaram, Mythily, Lau, Queenie, Withers, Teresa, Jeffree, Rosalind L., Reid, Lynne E., Da Silva, Leonard, Matsika, Admire, Niland, Colleen M., Cummings, Margaret C., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Anderson, Matthew J., Fink, J. Lynn ... Lakhani, Sunil R. (2015). Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significance. Journal of Pathology, 237 (3), 363-378. doi: 10.1002/path.4583

Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significance

2015

Journal Article

Which are more correctly diagnosed: conventional Papanicolaou smears or ThinPrep samples? A comparative study of 9 tears of external quality-assurance testing

Cummings, Margaret C., Marquart, Louise, Pelecanos, Anita M., Perkins, Gail, Papadimos, David, O'Rourke, Peter and Ross, Jennifer A. (2015). Which are more correctly diagnosed: conventional Papanicolaou smears or ThinPrep samples? A comparative study of 9 tears of external quality-assurance testing. Cancer Cytopathology, 123 (2), 108-116. doi: 10.1002/cncy.21498

Which are more correctly diagnosed: conventional Papanicolaou smears or ThinPrep samples? A comparative study of 9 tears of external quality-assurance testing

2015

Conference Publication

Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype

Kutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3

Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype

2014

Journal Article

Reply to J. Moline et al

Buchanan, Daniel D., Tan, Yen Y., Walsh, Michael D., Clendenning, Mark, Metcalf, Alexander M., Ferguson, Kaltin, Arnold, Sven T., Thompson, Bryony A., Lose, Felicity A., Parsons, Michael T., Walters, Rhiannon J., Pearson, Sally-Ann, Cummings, Margaret, Oehler, Martin K., Blomfield, Penelope B., Quinn, Michael A., Kirk, Judy A., Stewart, Colin J., Obermair, Andreas, Young, Joanne P., Webb, Penelope M. and Spurdle, Amanda B. (2014). Reply to J. Moline et al. Journal of Clinical Oncology, 32 (21), 2278-2279. doi: 10.1200/JCO.2014.55.8213

Reply to J. Moline et al

2014

Journal Article

COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment

Generali, D., Buffa, F. M., Deb, S., Cummings, M., Reid, L. E., Taylor, M., Andreis, D., Allevi, G., Ferrero, G., Byrne, D., Martinotti, M., Bottini, A., Harris, A. L., Lakhani, S. R. and Fox, S. B. (2014). COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment. British Journal of Cancer, 111 (1), 46-54. doi: 10.1038/bjc.2014.236

COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment

2014

Journal Article

Molecular classification of breast cancer

Vuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014). Molecular classification of breast cancer. Virchows Archiv, 465 (1), 1-14. doi: 10.1007/s00428-014-1593-7

Molecular classification of breast cancer

2014

Journal Article

Intratumour heterogeneity in the progression to breast cancer metastasis

Kutasovic, Jamie R., Sim, Sarah Y. M., McCart Reed, Amy E., Cummings, Margaret C. and Simpson, Peter T. (2014). Intratumour heterogeneity in the progression to breast cancer metastasis. Cancer Forum, 38 (2), 138-142.

Intratumour heterogeneity in the progression to breast cancer metastasis

2014

Journal Article

Metastatic progression of breast cancer: Insights from 50 years of autopsies

Cummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014). Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 (1), 23-31. doi: 10.1002/path.4288

Metastatic progression of breast cancer: Insights from 50 years of autopsies