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2016

Conference Publication

Inflammatory response sculpting by neutrophil inflammasomes

Chen, K., Gross, C., Wall, A., Stacey, K., Stow, J., Sweet, M. and Schroder, K. (2016). Inflammatory response sculpting by neutrophil inflammasomes. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

Inflammatory response sculpting by neutrophil inflammasomes

2016

Journal Article

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.

Schaale, K., Peters, K. M., Murthy, A. M., Fritzsche, A. K., Phan, M.-D., Totsika, M., Robertson, A. A. B., Nichols, K. B., Cooper, M. A., Stacey, K. J., Ulett, G. C., Schroder, K., Schembri, M. A. and Sweet, M. J. (2016). Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.. Mucosal Immunology, 9 (1), 124-136. doi: 10.1038/mi.2015.44

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.

2015

Journal Article

Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination"

Stacey, Katryn J., Watterson, Daniel, Modhiran, Naphak and Young, Paul R. (2015). Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination". Science Translational Medicine, 7 (318) 318lr4, 318lr4-318lr4. doi: 10.1126/scitranslmed.aad8657

Response to comment on "Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity" and "Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination"

2015

Journal Article

The inflammasome adaptor ASC induces procaspase-8 death effector domain filaments

Vajjhala, Parimala R., Lu, Alvin, Brown, Darren L., Pang, Siew Wai, Sagulenko, Vitaliya, Sester, David P., Cridland, Simon O., Hill, Justine M., Schroder, Kate, Stow, Jennifer L., Wu, Hao and Stacey, Katryn J. (2015). The inflammasome adaptor ASC induces procaspase-8 death effector domain filaments. Journal of Biological Chemistry, 290 (49), 29217-29230. doi: 10.1074/jbc.M115.687731

The inflammasome adaptor ASC induces procaspase-8 death effector domain filaments

2015

Journal Article

Response to Comment on "Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice".

Sester, David P. and Stacey, Katryn J. (2015). Response to Comment on "Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice".. Journal of Immunology, 195 (10), 4552-4553. doi: 10.4049/jimmunol.1501930

Response to Comment on "Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice".

2015

Journal Article

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

Modhiran, Naphak, Watterson, Daniel, Muller, David A., Panetta, Adele K., Sester, David P., Liu, Lidong, Hume, David A., Stacey, Katryn J. and Young, Paul R. (2015). Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Science Translational Medicine, 7 (304) 304ra142, 1-10. doi: 10.1126/scitranslmed.aaa3863

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

2015

Journal Article

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

Sester, David P., Sagulenko, Vitaliya, Thygesen, Sara J., Cridland, Jasmyn A., Loi, Yen Siew, Cridland, Simon O., Masters, Seth L., Genske, Ulrich, Hornung, Veit, Andoniou, Christopher E., Sweet, Matthew J., Degli-Esposti, Mariapia A., Schroder, Kate and Stacey, Katryn J. (2015). Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.. Journal of Immunology, 195 (3), 1233-1241. doi: 10.4049/jimmunol.1402859

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

2015

Journal Article

A novel pathway of cell death in response to cytosolic DNA in Drosophila cells

Vitak, Nazarii, Johnson, Karyn N., Sester, David P. and Stacey, Katryn J. (2015). A novel pathway of cell death in response to cytosolic DNA in Drosophila cells. Journal of Innate Immunity, 7 (2), 212-222. doi: 10.1159/000368276

A novel pathway of cell death in response to cytosolic DNA in Drosophila cells

2014

Journal Article

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

Chen, Kaiwen W., Groß, Christina J., Vasquez Sotomayor, Flor, Stacey, Katryn J., Tschopp, Jurg, Sweet, Matthew J. and Schroder, Kate (2014). The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge. Cell Reports, 8 (2), 570-582. doi: 10.1016/j.celrep.2014.06.028

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

2014

Journal Article

Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly

Vajjhala, Parimala R., Kaiser, Sebastian, Smith, Sarah J., Ong, Qi-Rui, Soh, Stephanie L., Stacey, Katryn J. and Hill, Justine M. (2014). Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly. Journal of Biological Chemistry, 289 (34), 23504-23519. doi: 10.1074/jbc.M114.553305

Identification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly

2014

Journal Article

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

Allam, Ramanjaneyulu, Lawlor, Kate E., Yu, Eric Chi-Wang, Mildenhall, Alison L., Moujalled, Donia M., Lewis, Rowena S., Ke, Francine, Mason, Kylie D., White, Michael J., Stacey, Katryn J., Strasser, Andreas, O'Reilly, Lorraine A., Alexander, Warren, Kile, Benjamin T., Vaux, David L. and Vince, James E. (2014). Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming. EMBO reports, 15 (9), 982-990. doi: 10.15252/embr.201438463

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

2013

Journal Article

Molecular mechanism for p202-mediated specific inhibition of aim2 inflammasome activation

Yin, Qian, Sester, David P., Tian, Yuan, Hsiao, Yu-Shan, Lu, Alvin, Cridland, Jasmyn A., Sagulenko, Vitaliya, Thygesen, Sara J., Choubey, Divaker, Hornung, Veit, Walz, Thomas, Stacey, Katryn J. and Wu, Hao (2013). Molecular mechanism for p202-mediated specific inhibition of aim2 inflammasome activation. Cell Reports, 4 (2), 327-339. doi: 10.1016/j.celrep.2013.06.024

Molecular mechanism for p202-mediated specific inhibition of aim2 inflammasome activation

2013

Journal Article

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection

Aachoui, Youssef, Sagulenko, Vitaliya, Miao, Edward A. and Stacey, Katryn J. (2013). Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection. Current Opinion in Microbiology, 16 (3), 319-326. doi: 10.1016/j.mib.2013.04.004

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection

2012

Journal Article

Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival

Liu, Xue Q., Stacey, Katryn J., Horne-Debets, Joshua M., Cridland, Jasmyn A., Fischer, Katja, Narum, David, Mackay, Fabienne, Pierce, Susan K. and Wykes, Michelle N. (2012). Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival. European Journal of Immunology, 42 (12), 3291-3301. doi: 10.1002/eji.201242689

Malaria infection alters the expression of B-cell activating factor resulting in diminished memory antibody responses and survival

2012

Journal Article

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

Schroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012). Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 (12), 1325-1329. doi: 10.1016/j.imbio.2012.07.020

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

2012

Journal Article

DEC-205 is a cell surface receptor for CpG oligonucleotides

Lahoud, Mireille H., Ahmet, Fatma, Zhang, Jian-Guo, Meuterb, Simone, Policheni, Antonia N., Kitsoulis, Susie, Lee, Chin-Nien, O’Keeffe, Meredith, Sullivan, Lucy C., Brooks, Andrew G., Berry, Richard, Rossjohn, Jamie, Mintern, Justine D., Vega-Ramos, Javier, Villadangos, Jose A., Nicola, Nicos A., Nussenzweig, Michel C., Stacey, Katryn J., Shortman, Ken, Heath, William R. and Caminschi, Irina (2012). DEC-205 is a cell surface receptor for CpG oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 109 (40), 16270-16275. doi: 10.1073/pnas.1208796109

DEC-205 is a cell surface receptor for CpG oligonucleotides

2012

Conference Publication

Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse

Sweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Oxford, United Kingdom: Wiley-Blackwell. doi: 10.1111/imm.12002

Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse

2011

Journal Article

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

Bokil, Nilesh J., Totsika, Makrina, Carey, Alison J., Stacey, Katryn J., Hancock, Viktoria, Saunders, Bernadette M., Ravasi, Timothy, Ulett, Glenn C., Schembri, Mark A. and Sweet, Matthew J. (2011). Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology, 216 (11), 1164-1171. doi: 10.1016/j.imbio.2011.05.011

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

2011

Journal Article

B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9

Roberts, Tara L., Turner, Marian L., Dunn, Jasmyn A., Lenert, Petar, Ross, Ian L., Sweet, Matthew J. and Stacey, Katryn J. (2011). B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9. Immunology and Cell Biology, 89 (4), 517-525. doi: 10.1038/icb.2010.112

B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9

2011

Journal Article

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes

Roberts, Tara L., Dunn, Jasmyn A., Sweet, Matthew J., Hume, David A. and Stacey, Katryn J. (2011). The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes. Molecular Immunology, 48 (8), 1027-1034. doi: 10.1016/j.molimm.2011.01.011

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes